Compounds > quinazolines
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quinazolines and idoxuridine

quinazolines has been researched along with idoxuridine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erlichman, C; Hedley, DW; Pressacco, J1
DeGoeij, K; Mester, J; Sluyser, M1
Chao, Y; Chen, FD; Chi, KH; Chou, SL; Liu, RS; Wang, HE; Wang, YS; Yen, SH1
Adjei, AA; Ames, MM; Atherton, P; Burch, P; Erlichman, C; Galanis, E; Goldberg, R; Pitot, H; Reid, J; Rubin, J; Safgren, SL; Sloan, J; Witzig, TE1
Bavetsias, V; Forster, MD; Gibbs, DD; Green, M; Henderson, E; Jackman, AL; Mitchell, F; Raynaud, F; Theti, DS; Valenti, M; Wood, N1

Trials

1 trial(s) available for quinazolines and idoxuridine

ArticleYear
Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Humans; Idoxuridine; Male; Middle Aged; Neoplasms; Nucleic Acid Synthesis Inhibitors; Quinazolines; Thiophenes

2001

Other Studies

4 other study(ies) available for quinazolines and idoxuridine

ArticleYear
ICI D1694 and idoxuridine: a synergistic antitumor combination.
    Cancer research, 1994, Jul-15, Volume: 54, Issue:14

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA Damage; Drug Synergism; Humans; Idoxuridine; Quinazolines; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured

1994
Modulation of [5-125I]iododeoxyuridine incorporation into tumour and normal tissue DNA by methotrexate and thymidylate synthase inhibitors.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Female; Fluorouracil; Idoxuridine; Intestine, Small; Iodine Radioisotopes; Liver; Mammary Neoplasms, Experimental; Methotrexate; Mice; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Quinazolines; Thiophenes; Thymidylate Synthase; Uracil

1996
Preclinical evaluation of locoregional delivery of radiolabeled iododeoxyuridine and thymidylate synthase inhibitor in a hepatoma model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:2

    Topics: Animals; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Idoxuridine; Iodine Radioisotopes; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Quinazolines; Rats; Rats, Sprague-Dawley; Thymidylate Synthase; Tumor Cells, Cultured

2001
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
    Cancer research, 2005, Dec-15, Volume: 65, Issue:24

    Topics: Animals; Apoptosis; Biological Transport; Carrier Proteins; Cell Proliferation; Choriocarcinoma; Enzyme Inhibitors; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Idoxuridine; Iodine Radioisotopes; Leukemia L1210; Lung Neoplasms; Membrane Transport Proteins; Mice; Mice, Nude; Ovarian Neoplasms; Quinazolines; Receptors, Cell Surface; Reduced Folate Carrier Protein; Thymidylate Synthase; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured

2005