Page last updated: 2024-08-21

quinazolines and homocysteine

quinazolines has been researched along with homocysteine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bagshawe, KD; Bradshaw, T; Mellor, B; Melton, RG; Pedley, RB; Searle, F; Sherwood, RF1
Algazy, K; Giantonio, B; Haller, DG; Hardy, C; Kluijtmans, LA; O'Dwyer, PJ; Redlinger, M; Stevenson, JP; Sun, W; Whitehead, AS1
Chen, CS; Chern, JW; Chien, TC; Yu, FH1
Beutel, G; Cassidy, J; Chick, J; Gill, S; Glen, H; Schöffski, P; Twelves, C1
Berlin, JD; Chick, J; Drolet, DW; Horan, J; Papadopoulos, KP; Quaratino-Baker, C; Ricart, AD; Rothenberg, ML; Rowinsky, EK; Syed, S; Tolcher, AW; Vermeulen, W1

Trials

3 trial(s) available for quinazolines and homocysteine

ArticleYear
Phase I clinical and pharmacogenetic trial of irinotecan and raltitrexed administered every 21 days to patients with cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Oct-15, Volume: 19, Issue:20

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Diarrhea; Dose-Response Relationship, Drug; Fatigue; Female; Genotype; Homocysteine; Humans; Irinotecan; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasms; Neutropenia; Oxidoreductases Acting on CH-NH Group Donors; Quinazolines; Thiophenes

2001
Phase I study of OSI-7904L, a novel liposomal thymidylate synthase inhibitor in patients with refractory solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-01, Volume: 11, Issue:15

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Deoxyuridine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genotype; Glutarates; Homocysteine; Humans; Infusions, Intravenous; Isoindoles; Liposomes; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Polymorphism, Genetic; Quinazolines; Sepsis; Thymidylate Synthase; Time Factors; Treatment Outcome

2005
Phase I, pharmacokinetic and biological correlative study of OSI-7904L, a novel liposomal thymidylate synthase inhibitor, and cisplatin in patients with solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Dec-01, Volume: 14, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Genotype; Glutarates; Homocysteine; Humans; Isoindoles; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Quinazolines; Thymidylate Synthase

2008

Other Studies

2 other study(ies) available for quinazolines and homocysteine

ArticleYear
Carboxypeptidase G2 and trimetrexate cause growth delay of human colonic cancer cells in vitro.
    Biochemical pharmacology, 1990, Jun-01, Volume: 39, Issue:11

    Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Cell Division; Colonic Neoplasms; Culture Media; Homocysteine; Humans; Methionine; Mice; Quinazolines; Rabbits; Trimetrexate; Tumor Cells, Cultured

1990
Nucleosides XI. Synthesis and antiviral evaluation of 5'-alkylthio-5'-deoxy quinazolinone nucleoside derivatives as S-adenosyl-L-homocysteine analogs.
    Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:12

    Topics: Antiviral Agents; Homocysteine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleosides; Quinazolines; S-Adenosylhomocysteine; Spectrometry, Mass, Fast Atom Bombardment

2004