Page last updated: 2024-08-21

quinazolines and halofuginone

quinazolines has been researched along with halofuginone in 138 studies

Research

Studies (138)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (31.16)	18.7374
1990's	43 (31.16)	18.2507
2000's	46 (33.33)	29.6817
2010's	6 (4.35)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Schein, E; Voigt, WP	1
Ferguson, AE; Leeson, S; Morrison, WD	1
Edgar, SA; Flanagan, C	2
Anderson, A; Christopher, DH; Woodhouse, RN	1
Ryley, JF; Wilson, RG	1
Casey, NH; Crosley, RI; Roosendaal, B; Smith, GA	1
Casey, NH; Crosley, RI; Smith, GA	1
Bocek, P; Foret, F; Krivánková, L	1
Adams, MH; Cabel, MC; Colberg, M; Izat, AL; Reiber, MA; Skinner, JT; Stilborn, HL; Waldroup, PW	1
Bartov, I; Granot, I; Hurwitz, S; Pines, M; Plavnik, I; Wax, E	1
Daniels, H; Halvorson, JC; Hoffbeck, SL; Noll, SL; Waibel, PE	1
Ares-Mazás, E; Peeters, JE; Theys, H; Vanopdenbosch, E; Villacorta, I	1
Cabel, MC; Waldroup, PW	1
Cabel, MC; Norton, RA; Waldroup, PW; Yazwinski, TA	1
de Vos, AJ; Shiels, I; Stewart, NP	1
Kinabo, LD; McKellar, QA; Murray, M	1
Mehlhorn, H; Raether, W	1
Dolan, TT	1
Lekaki, KA; Mbwambo, HA; Mkonyi, PA; Sondi, J	1
Baker, MN; Barrow, PA; Kirk, SJ; Simpson, JM	1
Ahmed, JS; Lendner, G; Sanft, S; Schein, E	1
Chema, S; Chumo, RS; Dolan, TT; Gathuma, JM; Irvin, AD; James, AD; Young, AS	1
Conder, GA; Folz, SD; Lee, BL; Nowakowski, LH	1
Cagniant, E; Devaux, P; Tillier, C	1
Enueme, JE; Grant, RJ; Halvorson, JC; Waibel, PE	1
Damron, BL; Fell, RV; Grant, RJ; Hebert, JA; Hellwig, HM; Johnson, ZB; Primo, RA; Siccardi, FJ; Waldroup, PW	1
Behr, KP; Lüders, H; Plate, C	1
Blagburn, BL; Ernest, JA; Lindsay, DS; Sundermann, CA	1
McDougald, LR	1
Chapman, HD	3
Humke, R; Kiltz, HH	1
Grant, RJ; Kennedy, T; Mathis, GF; McDougald, LR; Quarles, CL; Schwartz, J	1
Grant, RJ; Quarles, CL; Spencer, GK; Waibel, PE; Waldroup, PW	1
Chhabra, MB; Ruprah, NS; Sanyal, PK	1
Kitaly, JI; Maiseli, NC; Mkonyi, PA; Mleche, WC; Njau, BC	1
Divo, AA; Geary, TG; Jensen, JB	1
Ahmed, JS; Rehbein, G; Zweygarth, E	1
Bhattacharyulu, Y; Gill, BS; Kaur, D; Singh, A	1
Heydorn, AO; Voigt, WP	1
McHardy, N; Morgan, DW	1
Mehlhorn, H; Moltmann, U; Schein, E; Voigt, WP	1
De Vos, AJ; Roos, JA	1
Mathis, GF; McDougald, LR	1
Keshavarz, K; McDougald, LR	1
McDougald, LR; McQuistion, TE	1
Männer, K; Matuschka, FR	1
Anderson, A; Bliss, GW; Goodall, E; Woodhouse, RN	1
Norton, CC; Wise, DR	1
Bilgili, SF; Hess, JB; Pinion, JL	1
Bilgili, SF; Eckman, MK; Hess, JB; Pinion, JL	1
Rehg, JE	1
Brown, DM; Callow, AD; Choi, ET; Ryan, US; Sehgal, NL	1
Christensen, KD; Twining, P; Wyatt, CL; Zimmermann, NG	1
Naciri, M; Peeters, JE; Vanopdenbosch, E; Villacorta, I	1
Granot, I; Halevy, O; Hurwitz, S; Pines, M	1
Raghav, PR; Singh, DK; Thakur, M; Varshney, BC	1
Mancassola, R; Naciri, M; Peeters, JE; Yvoré, P	1
Chapman, HD; Hacker, AB	1
Buhr, RJ; Christensen, KD; Goodman, TN; Twining, PF; Wyatt, CL; Zimmermann, NG	1
Knopov, V; Levi-Schaffer, F; Nagler, A; Pines, M; Slavin, S	1
Cranfield, MR; Graczyk, TK; Hill, SL	1
Genina, O; Halevy, O; Levi-Schaffer, F; Nagler, A; Pines, M	1
Cotev, S; Feferman, R; Firman, N; Nagler, A; Pines, M; Shoshan, S	1
Nagler, A; Nyska, A; Nyska, M; Pines, M; Porat, S; Rivlin, E; Shoshan, S	1
Ernst, RA; Kratzer, FH; Kuhl, HJ; Vohra, P	1
Aingorn, H; Genina, O; Miao, HQ; Nagler, A; Pines, M; Vlodavsky, I	1
Daugschies, A; Haberkorn, A; Rommel, M; Stephen, B	1
Genina, O; Knopov, V; Lavelin, I; Nagler, A; Pines, M	1
Aingorn, H; Condiotti, R; Genina, O; Katz, A; Miao, HQ; Nagler, A; Pines, M; Vlodavsky, I	1
Nagler, A; Pines, M	2
McDougald, LR; Seibert, BP	1
Genina, O; Lavelin, I; Levi-Schaffer, F; Nagler, A; Pines, M; Raphael, J; Rivkind, AI	1
Daugschies, A; Gässlein, U; Rommel, M	1
Mehlhorn, H; Schein, E	1
Abe, T; Goto, Y; Iijima, K; Kondon, K; Liu, K; Matsukawa, M; Sekine, S; Yamagishi, I	1
Genina, O; Lavelin, I; Nagler, A; Ohana, M; Pines, M	1
Ariel, I; de-Groot, N; Elkin, M; Hochberg, A; Miao, HQ; Nagler, A; Pines, M; Vlodavsky, I	1
Aingorn, E; de-Groot, N; Elkin, M; Hochberg, A; Nagler, A; Pines, M; Reich, R; Vlodavsky, I	1
Albala, DM; Jahoda, A; Koleski, FC; Turk, TM; Wojcik, E	1
Abramovitch, R; Dafni, H; Nagler, A; Neeman, M; Pines, M	1
Genina, O; Gofrit, O; Nagler, A; Ohana, M; Pines, M; Pode, D	1
Nowak, RA	1
Aingorn, E; Dou, HL; Elkin, M; Hemo, I; Miao, HQ; Nagler, A; Pines, M; Reich, R; Vlodavsky, I	1
Sule, SD; Wigley, FM	1
Black, CM; Denton, CP	1
Aeed, H; Alexiev, R; Avni, Y; Bruck, R; Genina, O; Nagler, A; Pines, M	1
Chermette, R; Lefay, D; Naciri, M; Poirier, P	1
Alexiev, R; Domb, A; Genina, O; Inbar, J; Nagler, A; Ohana, M; Pines, M	1
Covey, JM; Egorin, MJ; Eiseman, JL; Hamburger, DR; Parise, RA; Stecklair, KP	1
Bona, C; McGaha, TL; Phelps, RG; Spiera, H	1
Barak, V; Eshhar, Z; Gavish, Z; Nagler, A; Pines, M; Pinthus, JH; Ramon, J	1
Nishioka, K; Yamamoto, T	1
Harris, AL; Streeter, EH	1
Breuer, R; Goldstein, RH; Or, R; Segel, MJ; Tzurel, A	1
Alexiev, R; Anbinder, N; Genina, O; Mawasi, N; Paizi, M; Pines, M; Spira, G	1
Bona, CA; Kodera, T; McGaha, TL; Pines, M; Spiera, H; Stan, AC	1
Bona, C; Kodera, T; McGaha, T; Phelps, R; Pines, M; Spiera, H	1
Daugschies, A; Joachim, A; Krull, T; Schwarzkopf, J	1
Berkelhammer, G	1
Cannavan, A; Elliott, CT; Kennedy, DG; Lövgren, T; Yakkundi, S	1
Nagler, A; Pines, M; Snyder, D; Yarkoni, S	1
Dafni, H; Gross, DJ; Nagler, A; Neeman, M; Pines, M; Reibstein, I; Slavin, S; Weiss, L	1
Ali-El-Dein, B; Bazeed, M; Hafez, AT; Jaidane, M; Mohsen, T; Ounaies, A	1
Felici, A; Flanders, KC; Fujii, M; Javelaud, D; Mauviel, A; Mitchell, JB; Piek, E; Reiss, M; Roberts, AB; Russo, A; Samuni, AM; Sowers, A; Xavier, S; Yarkoni, S	1
Abu-Amara, SN; Bruck, R; Geiger, B; Genina, O; Gnainsky, Y; Monsonego-Ornan, E; Nagler, A; Paizi, M; Pines, M; Spira, G	1
Doğusoy, G; Gümüştaş, K; Ozçelik, MF; Pekmezci, S; Saribeyoğlu, K; Unal, E	1
Al-Hendy, A; Copland, JA; Young, SL	1
Alper, R; Ilan, Y; Nagler, A; Ohana, M; Pines, M; Shapira, MY; Shibolet, O; Vlodavsky, I	1
Cadeddu, JA; Duchene, DA; Jacomides, L; Johnson, BD; Lindberg, G; Ogan, K; Pearle, MS	1
Daeseleire, E; Delahaut, P; Huet, AC; Mortier, L; Van Peteghem, C	1
Covey, JM; Egorin, MJ; Grossi, IM; Merrill, JW; Parise, RA; Peggins, JO; Sparrow, BR	1
Fevery, J; Nevens, F; Roskams, T; Van de Casteele, M; Van der Elst, I; van Pelt, JF	1
Holland, WG	1
Bruno, W; Heller, L; Klitzman, B; Levin, LS; Meade, R; Olbrich, KC	1
Daeseleire, E; Delahaut, P; Elliott, C; Fodey, T; Huet, AC; Mortier, L	1
Jarvie, BD; Leslie, KE; McKnight, DR; Peregrine, AS; Sharpe, PH; Todd, CG; Trotz-Williams, LA; Wallace, MM	1
Fridman, E; Genina, O; Mor, Y; Nagler, A; Pines, M; Pinthus, JH; Sheffer, Y	1
Arbell, D; Genina, O; Koplewitz, BZ; Nagler, A; Ohana, M; Pines, M; Udassin, R	1
Connolly, CM; Lawler, J; Pines, M; Yee, KO	1
Bauer, M; Niedobitek, E; Patsenker, E; Popov, Y; Schulze-Krebs, A; Schuppan, D	1
Haran, N; Leschinski, L; Pines, M; Rapoport, J	1
Eliashar, R; Maly, B; Nagler, A; Ochana, M; Pines, M; Sichel, JY	1
Bièche, I; Blanc, JF; Dugot-Senant, N; Laurendeau, I; Pines, M; Rosenbaum, J; Rullier, A; Taras, D	1
Cahalon, L; Hecht, I; Leiba, M; Lider, O; Nagler, A; Sela, U; Shimoni, A; Vlodavsky, I; Zanin-Zhorov, A	1
de Jonge, MJ; Dumez, H; Lacombe, D; Marréaud, S; Punt, CJ; Snyder, D; van Oosterom, A; Verweij, J; Yamaguchi, T; Yarkoni, S	1
Samant, BS; Sukhthankar, MG	1
Evans, P; McLaughlin, NP	1
Cortese, JF; Dignam, JD; Edenius, M; Hendrick, M; Keller, TL; Kim, YJ; Lee, HK; Mazitschek, R; Rao, A; Sundrud, MS; Whitman, M; Wirth, DF; Yeo, CY; Yum, J; Zocco, D	1
Schimmel, P; Sun, L; Yang, XL; Zhou, H	1
Evans, P; McLaughlin, NP; Pines, M	1
Bopp, SE; Clardy, J; Clish, CB; Cortese, JF; Derbyshire, ER; Estiu, G; Galinsky, K; Herman, JD; Keller, TL; Lindquist, S; Lukens, AK; Mazitschek, R; Mota, MM; Patel, V; Pepper, LR; Ribacke, U; Santos, SA; Schimmel, P; Sullivan, WJ; Whitman, M; Wiest, O; Wirth, DF; Zhou, H; Zuzarte-Luis, V	1
Evans, P; McLaughlin, NP; Smullen, S	1

Reviews

8 review(s) available for quinazolines and halofuginone

Article	Year
Halofuginone: a novel antifibrotic therapy. General pharmacology, 1998, Volume: 30, Issue:4 Topics: Animals; Collagen; Fibrosis; Humans; Liver Cirrhosis; Piperidines; Postoperative Complications; Protein Synthesis Inhibitors; Pulmonary Fibrosis; Quinazolines; Quinazolinones; Skin; Tissue Adhesions	1998
Novel therapy in the treatment of scleroderma. Expert opinion on investigational drugs, 2001, Volume: 10, Issue:1 Topics: Autoimmune Diseases; Bone Marrow Transplantation; Cysteine; Humans; Interferon-gamma; Nitric Oxide; Piperidines; Prostaglandins; Quinazolines; Quinazolinones; Relaxin; Scleroderma, Systemic; Tetracycline; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha	2001
Novel therapeutic strategies in scleroderma. Current rheumatology reports, 1999, Volume: 1, Issue:1 Topics: Clinical Trials as Topic; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Minocycline; Nitric Oxide; Piperidines; Prognosis; Quinazolines; Quinazolinones; Relaxin; Scleroderma, Systemic; Treatment Outcome	1999
Angiogenesis in bladder cancer--prognostic marker and target for future therapy. Surgical oncology, 2002, Volume: 11, Issue:1-2 Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Cyclohexanes; DNA-Binding Proteins; Drug Combinations; Endothelial Growth Factors; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Lymphokines; Mice; Mice, Nude; Neovascularization, Pathologic; Nuclear Proteins; O-(Chloroacetylcarbamoyl)fumagillol; Piperidines; Quinazolines; Quinazolinones; Sesquiterpenes; Thymidine Phosphorylase; Transcription Factors; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2002
Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2003, Volume: 9, Issue:7 Topics: Administration, Cutaneous; Animals; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Collagen Type I; Fibrosis; Graft vs Host Disease; Humans; Mice; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Scleroderma, Systemic	2003
Potential nonhormonal therapeutics for medical treatment of leiomyomas. Seminars in reproductive medicine, 2004, Volume: 22, Issue:2 Topics: Bexarotene; Female; Heparin; Humans; Interferon-alpha; Leiomyoma; ortho-Aminobenzoates; Piperidines; Pyridones; Quinazolines; Quinazolinones; Reproduction; Tetrahydronaphthalenes; Thiazolidinediones; Tocopherols; Uterine Neoplasms	2004
The chemistry and biology of febrifugine and halofuginone. Bioorganic & medicinal chemistry, 2014, Apr-01, Volume: 22, Issue:7 Topics: Antimalarials; Humans; Molecular Structure; Parasitic Sensitivity Tests; Piperidines; Plasmodium; Quinazolines; Quinazolinones; Structure-Activity Relationship	2014
Chemical synthesis of febrifugine and analogues. Bioorganic & medicinal chemistry, 2018, 05-15, Volume: 26, Issue:9 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Cyclization; Cycloaddition Reaction; Humans; Piperidines; Plasmodium falciparum; Quinazolines; Quinazolinones; Stereoisomerism	2018

Trials

7 trial(s) available for quinazolines and halofuginone

Article	Year
Influence of phased inclusion of halofuginone on broiler skin tensile strength and growth performance. Journal of the South African Veterinary Association, 1992, Volume: 63, Issue:1 Topics: Animals; Chickens; Coccidiostats; Piperidines; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength	1992
Influence of continuous dietary halofuginone on broiler skin tensile strength and growth performance. Journal of the South African Veterinary Association, 1992, Volume: 63, Issue:1 Topics: Animals; Chickens; Coccidiostats; Female; Food Additives; Male; Piperidines; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength	1992
Clinical trial of halofuginone lactate for the treatment of East Coast fever in Kenya. The Veterinary record, 1987, Jun-13, Volume: 120, Issue:24 Topics: Animals; Antiprotozoal Agents; Cattle; Clinical Trials as Topic; Follow-Up Studies; Kenya; Quinazolines; Quinazolinones; Theileriasis	1987
Efficacy of halofuginone lactate in the prevention of cryptosporidiosis in suckling calves. The Veterinary record, 2001, Jan-27, Volume: 148, Issue:4 Topics: Administration, Oral; Animals; Animals, Suckling; Antiprotozoal Agents; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Double-Blind Method; Feces; Female; Male; Parasite Egg Count; Quinazolines; Quinazolinones; Time Factors; Treatment Outcome	2001
Prevalence and control of bovine cryptosporidiosis in German dairy herds. Veterinary parasitology, 2003, Mar-25, Volume: 112, Issue:4 Topics: Animals; Anti-Infective Agents; Cattle; Cattle Diseases; Coccidiostats; Cryptosporidiosis; Cryptosporidium; Dairying; Diarrhea; Feces; Female; Germany; Oocysts; Piperidines; Prevalence; Quinazolines; Quinazolinones; Sulfamethazine; Surveys and Questionnaires	2003
Effect of halofuginone lactate on the occurrence of Cryptosporidium parvum and growth of neonatal dairy calves. Journal of dairy science, 2005, Volume: 88, Issue:5 Topics: Animals; Animals, Newborn; Cattle; Cattle Diseases; Coccidiostats; Cryptosporidiosis; Cryptosporidium parvum; Diarrhea; Feces; Male; Placebos; Quinazolines; Quinazolinones; Weaning; Weight Gain	2005
Phase I and pharmacokinetic study of halofuginone, an oral quinazolinone derivative in patients with advanced solid tumours. European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:12 Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Fatigue; Humans; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasms; Piperidines; Quinazolines; Quinazolinones; Vomiting	2006

Other Studies

123 other study(ies) available for quinazolines and halofuginone

Article	Year
Chemotherapy of bovine theileriosis with Halofuginone. Short communication. Acta tropica, 1979, Volume: 36, Issue:4 Topics: Animals; Apicomplexa; Body Temperature; Cattle; Piperidines; Quinazolines; Quinazolinones; Species Specificity; Theileriasis	1979
Efficacy of salinomycin and stenorol against various species of Eimeria and effect on chick performance. Poultry science, 1979, Volume: 58, Issue:5 Topics: Animals; Chickens; Coccidiosis; Coccidiostats; Ionophores; Male; Monensin; Piperidines; Poultry Diseases; Pyrans; Quinazolines; Quinazolinones; Roxarsone	1979
Efficacy of Stenorol (halofuginone). I. Against recent field isolates of six species of chicken coccidia. Poultry science, 1979, Volume: 58, Issue:6 Topics: Animals; Body Weight; Chickens; Coccidiosis; Coccidiostats; Drug Resistance; Eimeria; Feeding Behavior; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones	1979
Efficacy of Stenorol (halofuginone). II. Plus roxarsone or bacitracin MD against selected strains of chicken Eimeria. Poultry science, 1979, Volume: 58, Issue:6 Topics: Animals; Arsenicals; Bacitracin; Body Weight; Chickens; Coccidiosis; Coccidiostats; Drug Combinations; Eimeria; Feeding Behavior; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Roxarsone; Salicylates	1979
Analysis of the anti-coccidial drug, halofunginone, in chicken feed using gas-liquid chromatography and high-performance liquid chromatography. Journal of chromatography, 1979, Jan-21, Volume: 168, Issue:2 Topics: Animal Feed; Animals; Chickens; Chromatography, Gas; Chromatography, High Pressure Liquid; Coccidiostats; Food, Fortified; Methods; Minerals; Piperidines; Quinazolines; Quinazolinones	1979
Laboratory studies with some recent anticoccidials. Parasitology, 1975, Volume: 70, Issue:2 Topics: Administration, Oral; Animal Feed; Animals; Chickens; Coccidiosis; Coccidiostats; Eimeria; Feces; Lasalocid; Monensin; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones	1975
Determination of halofuginone in feedstuffs by the combination of capillary isotachophoresis and capillary zone electrophoresis in a column-switching system. Journal of chromatography, 1991, Jun-07, Volume: 545, Issue:2 Topics: Animal Feed; Animals; Coccidiostats; Electrophoresis; Piperidines; Poultry; Quinazolines; Quinazolinones	1991
Comparison of different anticoccidials on processing characteristics and parts yield of broiler chickens. Poultry science, 1991, Volume: 70, Issue:6 Topics: Animals; Body Weight; Chickens; Coccidiostats; Eating; Female; Male; Monensin; Muscle Development; Muscles; Piperidines; Pyrans; Quinazolines; Quinazolinones; Random Allocation	1991
Increased skin tearing in broilers and reduced collagen synthesis in skin in vivo and in vitro in response to the coccidiostat halofuginone. Poultry science, 1991, Volume: 70, Issue:7 Topics: Animals; Cells, Cultured; Chickens; Coccidiostats; Collagen; Dose-Response Relationship, Drug; Female; Fibroblasts; Monensin; Nicarbazin; Piperidines; Quinazolines; Quinazolinones; Random Allocation; Skin; Weight Gain	1991
Influence of virginiamycin on growth and efficiency of large white turkeys. Poultry science, 1991, Volume: 70, Issue:4 Topics: Amebicides; Amprolium; Animal Feed; Animals; Arsanilic Acid; Drug Interactions; Eating; Energy Metabolism; Female; Male; Monensin; Mortality; Piperidines; Quinazolines; Quinazolinones; Sex Characteristics; Turkeys; Virginiamycin; Weight Gain	1991
Efficacy of halofuginone lactate against Cryptosporidium parvum in calves. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:2 Topics: Animals; Animals, Newborn; Cattle; Cattle Diseases; Cryptosporidiosis; Dose-Response Relationship, Drug; Feces; Kinetics; Male; Quinazolines; Quinazolinones	1991
Effects of different coccidiostats on performance of large white turkeys. Poultry science, 1991, Volume: 70, Issue:2 Topics: Amprolium; Animal Feed; Animals; Coccidiostats; Dietary Fats; Dinitolmide; Eating; Female; Male; Monensin; Organotin Compounds; Piperidines; Pyrimidines; Quinazolines; Quinazolinones; Random Allocation; Sulfadimethoxine; Turkeys; Weight Gain	1991
Efficacy of different anticoccidials against experimental coccidiosis in large white turkeys. Poultry science, 1991, Volume: 70, Issue:2 Topics: Amprolium; Animals; Coccidiosis; Coccidiostats; Dinitolmide; Feces; Intestines; Male; Monensin; Organotin Compounds; Piperidines; Poultry Diseases; Pyrimidines; Quinazolines; Quinazolinones; Sulfadimethoxine; Turkeys; Weight Gain	1991
Elimination of Theileria buffeli infections from cattle by concurrent treatment with primaquine phosphate and halofuginone lactate. Tropical animal health and production, 1990, Volume: 22, Issue:2 Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Apicomplexa; Cattle; Drug Therapy, Combination; Fluorescent Antibody Technique; Piperidines; Primaquine; Quinazolines; Quinazolinones; Recurrence; Splenectomy; Theileriasis	1990
Determination of halofuginone in bovine plasma by competing-ion high performance liquid chromatography after solid phase extraction. Biomedical chromatography : BMC, 1989, Volume: 3, Issue:3 Topics: Administration, Oral; Animals; Cattle; Chromatography, High Pressure Liquid; Coccidiostats; Indicators and Reagents; Microchemistry; Piperidines; Quinazolines; Quinazolinones	1989
Effects of halofuginone lactate on lymphocytes and MDBK cells infected with Theileria annulata and/or vesicular stomatitis virus (VSV): an in vitro study. Parasitology research, 1988, Volume: 74, Issue:5 Topics: Animals; Apicomplexa; Cattle; Cell Line; Cell Survival; Cells, Cultured; Lymphocytes; Microscopy, Electron; Quinazolines; Quinazolinones; Theileriasis; Vesicular stomatitis Indiana virus	1988
Chemotherapy of East Coast fever. Treatment of infections induced by isolates of Theileria parva with halofuginone. Acta tropica, 1986, Volume: 43, Issue:2 Topics: Animals; Antiprotozoal Agents; Body Weight; Carrier State; Cattle; Leukocyte Count; Lymph Nodes; Male; Piperidines; Quinazolines; Quinazolinones; Theileriasis; Ticks	1986
Chemotherapy of field cases of East Coast fever using halofuginone lactate. Acta tropica, 1986, Volume: 43, Issue:4 Topics: Animals; Antiprotozoal Agents; Cattle; Quinazolines; Quinazolinones; Theileriasis	1986
The effect of halofuginone on the excretion of Salmonella typhimurium by experimentally infected chickens. Veterinary microbiology, 1988, Volume: 17, Issue:1 Topics: Animal Feed; Animals; Chickens; Coccidiostats; Colony Count, Microbial; Feces; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Salmonella Infections, Animal; Salmonella typhimurium; Specific Pathogen-Free Organisms	1988
Effect of chemotherapy on the biological functions of lymphoblastoid cells infected with Theileria annulata. Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1987, Volume: 34, Issue:6 Topics: Animals; Antiprotozoal Agents; Apicomplexa; Lymphocytes; Naphthoquinones; Quinazolines; Quinazolinones; Theileriasis; Triazines	1987
Anticoccidial evaluation of halofuginone, lasalocid, maduramicin, monensin and salinomycin. Veterinary parasitology, 1988, Volume: 28, Issue:1-2 Topics: Animals; Anti-Bacterial Agents; Body Weight; Chickens; Coccidiosis; Coccidiostats; Eimeria; Female; Ionophores; Lactones; Lasalocid; Male; Monensin; Piperidines; Poultry Diseases; Pyrans; Quinazolines; Quinazolinones	1988
Determination of halofuginone in poultry feeds by high-performance liquid chromatography. Journal of chromatography, 1988, Jun-10, Volume: 441, Issue:2 Topics: Animal Feed; Chromatography, High Pressure Liquid; Coccidiostats; Piperidines; Quinazolines; Quinazolinones; Solvents; Spectrophotometry, Ultraviolet	1988
Efficacy of halofuginone as a coccidiostat for turkeys. Poultry science, 1987, Volume: 66, Issue:10 Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Coccidiosis; Coccidiostats; Male; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Turkeys	1987
Response of broiler chickens to addition of bacitracin methylene disalicylate and roxarsone to diets containing halofuginone. Poultry science, 1987, Volume: 66, Issue:10 Topics: Animal Feed; Animals; Arsenicals; Bacitracin; Body Weight; Chickens; Coccidiosis; Coccidiostats; Female; Food Additives; Male; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Roxarsone	1987
[Tolerance of halofuginone (Stenorol) by geese (Anser anser f. dom.), flight ducks (Cairina moschata f. dom.) and Peking ducks (Anas platyrhynchos f. dom.)]. DTW. Deutsche tierarztliche Wochenschrift, 1986, Jan-07, Volume: 93, Issue:1 Topics: Animals; Body Weight; Coccidiostats; Ducks; Eating; Geese; Piperidines; Quinazolines; Quinazolinones	1986
Chemoprophylaxis of cryptosporidiosis in chickens, using halofuginone, salinomycin, lasalocid, or monensin. American journal of veterinary research, 1987, Volume: 48, Issue:3 Topics: Animals; Chickens; Coccidiostats; Cryptosporidiosis; Lasalocid; Monensin; Piperidines; Poultry Diseases; Pyrans; Quinazolines; Quinazolinones	1987
Halofuginone: laboratory titration of anticoccidial activity in young turkeys. Poultry science, 1986, Volume: 65, Issue:2 Topics: Animals; Body Weight; Coccidiosis; Coccidiostats; Feeding Behavior; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Turkeys	1986
Eimeria tenella: stability of resistance to halofuginone, decoquinate and arprinocid in the chicken. Research in veterinary science, 1986, Volume: 40, Issue:1 Topics: Adenine; Animals; Chickens; Coccidiosis; Coccidiostats; Decoquinate; Drug Resistance; Eimeria; Hydroxyquinolines; Piperidines; Quinazolines; Quinazolinones	1986
Eimeria tenella: experimental studies on the development of resistance to halofuginone. Veterinary parasitology, 1986, Volume: 21, Issue:2 Topics: Animals; Chickens; Coccidiosis; Coccidiostats; Drug Resistance, Microbial; Eimeria; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones	1986
Bovine theileriosis in Burundi: chemotherapy with halofuginone lactate. Tropical animal health and production, 1986, Volume: 18, Issue:3 Topics: Animals; Burundi; Cattle; Piperidines; Quinazolines; Quinazolinones; Theileriasis	1986
Anticoccidial efficacy of halofuginone in turkeys reared to market weight. Poultry science, 1986, Volume: 65, Issue:9 Topics: Animals; Coccidiosis; Coccidiostats; Female; Male; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Turkeys	1986
The use of bambermycins (Flavomycin) and halofuginone (Stenorol) in diets for growing turkeys. Poultry science, 1985, Volume: 64, Issue:7 Topics: Animals; Anti-Bacterial Agents; Arkansas; Bambermycins; Body Weight; Coccidiostats; Colorado; Female; Food Additives; Male; Minnesota; Piperidines; Quinazolines; Quinazolinones; Sex Factors; Turkeys	1985
Chemotherapeutic efficacy of sulphadimidine, amprolium, halofuginone and chloroquine phosphate in experimental Eimeria bareillyi coccidiosis of buffaloes. Veterinary parasitology, 1985, Volume: 17, Issue:2 Topics: Amprolium; Animals; Buffaloes; Chloroquine; Coccidiosis; Coccidiostats; Eimeria; Intestine, Small; Piperidines; Quinazolines; Quinazolinones; Sulfamethazine	1985
Treatment of field cases of East Coast fever with halofuginone lactate. Tropical animal health and production, 1985, Volume: 17, Issue:4 Topics: Animals; Cattle; Piperidines; Quinazolines; Quinazolinones; Theileriasis; Tick Infestations	1985
An in vitro assay system for the identification of potential antimalarial drugs. The Journal of parasitology, 1983, Volume: 69, Issue:3 Topics: Animals; Antimalarials; Cattle; Chloramphenicol; Chloroquine; Clindamycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Piperidines; Plasmodium falciparum; Quinazolines; Quinazolinones; Rabbits	1983
Development by genetic recombination of a line of Eimeria tenella resistant to robenidine, decoquinate and amprolium. Zeitschrift fur Parasitenkunde (Berlin, Germany), 1984, Volume: 70, Issue:4 Topics: Adenine; Amprolium; Animals; Chickens; Clopidol; Coccidiostats; Decoquinate; Drug Resistance, Microbial; Eimeria; Guanidines; Hydroxyquinolines; Picolines; Piperidines; Quinazolines; Quinazolinones; Recombination, Genetic; Robenidine	1984
The effect of halofuginone, Wellcome 993 C, oxytetracycline, and diminazene diaceturate on Babesia equi-infected lymphoblastoid cell cultures. The Journal of parasitology, 1984, Volume: 70, Issue:4 Topics: Amidines; Animals; Antiprotozoal Agents; Babesia; Cell Line; Diminazene; DNA; Lymphocytes; Naphthoquinones; Oxytetracycline; Piperidines; Quinazolines; Quinazolinones; Thymidine	1984
Chemotherapy of bovine tropical theileriosis: Theileria annulata infection. Research in veterinary science, 1984, Volume: 37, Issue:2 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Cattle; Drug Administration Schedule; Injections, Intramuscular; Piperidines; Quinazolines; Quinazolinones; Theileriasis	1984
Determination of halofuginone hydrobromide in medicated animal feeds. The Analyst, 1983, Volume: 108, Issue:1291 Topics: Animal Feed; Chromatography, High Pressure Liquid; Coccidiostats; Piperidines; Quinazolines; Quinazolinones	1983
Collaborative study of a method for the determination of residues of halofuginone in chicken tissue. Analytical Methods Committee, Royal Society of Chemistry. The Analyst, 1984, Volume: 109, Issue:2 Topics: Animals; Chickens; Chromatography, High Pressure Liquid; Coccidiostats; Meat; Piperidines; Quinazolines; Quinazolinones	1984
Chemotherapy of Sarcosporidiosis and theileriosis in domestic animals. Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious..., 1981, Volume: 250, Issue:1-2 Topics: Animals; Cattle; Coccidiostats; Drug Combinations; Goats; Oxytetracycline; Piperidines; Quinazolines; Quinazolinones; Sarcocystosis; Sheep; Sheep Diseases; Sulfadoxine; Theileriasis; Trimethoprim	1981
Comparison of the antitheilerial effect of Wellcome 993C and halofuginone. Research in veterinary science, 1982, Volume: 32, Issue:1 Topics: Animals; Antiprotozoal Agents; Apicomplexa; Cattle; Coccidiostats; Lymph Nodes; Male; Naphthoquinones; Piperidines; Quinazolines; Quinazolinones; Theileriasis	1982
Electron microscopical study on the effect of halofuginone on Theileria parva. Tropenmedizin und Parasitologie, 1981, Volume: 32, Issue:4 Topics: Animals; Apicomplexa; Cattle; Cattle Diseases; Lymphocytes; Piperidines; Quinazolines; Quinazolinones; Theileriasis	1981
Chemotherapy of Theileria parva lawrencei infections in cattle with halofuginone. The Onderstepoort journal of veterinary research, 1983, Volume: 50, Issue:1 Topics: Animals; Cattle; Coccidiostats; Piperidines; Quinazolines; Quinazolinones; Theileriasis	1983
Drug responsiveness of field isolates of chicken Coccidia. Poultry science, 1982, Volume: 61, Issue:1 Topics: Amprolium; Animals; Chickens; Coccidiostats; Drug Resistance; Eimeria; Intestines; Manure; Nicarbazin; Piperidines; Quinazolines; Quinazolinones; Robenidine	1982
Anticoccidial drugs: growth and performance depressing effects in young chickens. Poultry science, 1982, Volume: 61, Issue:4 Topics: Adenine; Animal Feed; Animals; Body Weight; Chickens; Coccidiostats; Growth; Lasalocid; Male; Monensin; Nicarbazin; Piperidines; Quinazolines; Quinazolinones	1982
Anticoccidial activity of arprinocid and halofuginone. Veterinary parasitology, 1981, Volume: 9, Issue:1 Topics: Adenine; Animals; Chickens; Coccidiosis; Coccidiostats; Eimeria; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Species Specificity	1981
[The development of weaned piglets experimentally infected with Isospora suis as a model for the effect of lasalocid and halofuginone on coccidia (author's transl)]. Zentralblatt fur Bakteriologie. 1. Abt. Originale. A: Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1981, Volume: 248, Issue:4 Topics: Animals; Body Weight; Coccidiosis; Feces; Isospora; Lasalocid; Piperidines; Quinazolines; Quinazolinones; Swine; Weaning	1981
Analysis of the anti-coccidial drug, halofuginone, in chicken tissue and chicken feed using high-performance liquid chromatography. Journal of chromatography, 1981, Aug-07, Volume: 212, Issue:3 Topics: Animal Feed; Animals; Chickens; Chromatography, High Pressure Liquid; Coccidiostats; Piperidines; Quinazolines; Quinazolinones; Tissue Distribution	1981
Anticoccidial drugs for preventive therapy in intensively reared pheasants. The Veterinary record, 1981, Dec-19, Volume: 109, Issue:25-26 Topics: Animals; Bird Diseases; Birds; Clopidol; Coccidiosis; Coccidiostats; Piperidines; Quinazolines; Quinazolinones	1981
The effects of halofuginone and salinomycin, alone and in combination, on live performance and skin characteristics of female broilers: influence of a high-proline diet supplemented with ascorbic acid and zinc. Poultry science, 1995, Volume: 74, Issue:2 Topics: Animals; Ascorbic Acid; Body Weight; Chickens; Coccidiostats; Female; Food, Fortified; Piperidines; Proline; Pyrans; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength; Zinc	1995
The effects of halofuginone and salinomycin, alone and in combination, on live performance and skin characteristics of broilers. Poultry science, 1995, Volume: 74, Issue:2 Topics: Animals; Body Weight; Chickens; Coccidiostats; Female; Food, Fortified; Male; Piperidines; Pyrans; Quinazolines; Quinazolinones; Sex Factors; Skin; Skin Physiological Phenomena; Tensile Strength	1995
The activity of halofuginone in immunosuppressed rats infected with Cryptosporidium parvum. The Journal of antimicrobial chemotherapy, 1995, Volume: 35, Issue:3 Topics: Animals; Colonic Diseases; Common Bile Duct; Cryptosporidiosis; Cryptosporidium parvum; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Feces; Female; Immunosuppression Therapy; Intestine, Large; Intestine, Small; Parasite Egg Count; Piperidines; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Treatment Outcome	1995
Halofuginone, a specific collagen type I inhibitor, reduces anastomotic intimal hyperplasia. Archives of surgery (Chicago, Ill. : 1960), 1995, Volume: 130, Issue:3 Topics: Anastomosis, Surgical; Animals; Blotting, Northern; Carotid Artery, Common; Cell Division; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Hyperplasia; Muscle, Smooth, Vascular; Piperidines; Procollagen; Quinazolines; Quinazolinones; Rabbits; RNA, Messenger; Tropoelastin; Tunica Intima	1995
Effect of halofuginone on broiler skin strength when used in a shuttle anticoccidial program. Poultry science, 1994, Volume: 73, Issue:2 Topics: Animal Feed; Animals; Chickens; Coccidiostats; Diet; Drug Administration Schedule; Female; Piperidines; Pyrans; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength	1994
Specific serum and local antibody responses against Cryptosporidium parvum during medication of calves with halofuginone lactate. Infection and immunity, 1993, Volume: 61, Issue:10 Topics: Animals; Antibodies, Protozoan; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium parvum; Male; Parasite Egg Count; Quinazolines; Quinazolinones	1993
Halofuginone: an inhibitor of collagen type I synthesis. Biochimica et biophysica acta, 1993, Feb-13, Volume: 1156, Issue:2 Topics: Animals; Birds; Cell Division; Cells, Cultured; Coccidiostats; Collagen; Embryo, Mammalian; Embryo, Nonmammalian; Fibroblasts; Gene Expression; Growth Plate; Matrix Metalloproteinase Inhibitors; Mice; Piperidines; Proline; Quinazolines; Quinazolinones; Rats; Species Specificity	1993
Chemotherapeutic trials with four drugs in crossbred calves experimentally infected with Theileria annulata. Research in veterinary science, 1993, Volume: 54, Issue:1 Topics: Animals; Antiprotozoal Agents; Cattle; Male; Naphthoquinones; Oxytetracycline; Quinazolines; Quinazolinones; Theileria annulata; Theileriasis	1993
The effect of halofuginone lactate on experimental Cryptosporidium parvum infections in calves. Veterinary parasitology, 1993, Volume: 45, Issue:3-4 Topics: Animals; Animals, Newborn; Antiprotozoal Agents; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium parvum; Dose-Response Relationship, Drug; Feces; Female; Male; Quinazolines; Quinazolinones	1993
The effects of shuttle programs upon the growth of broilers and the development of immunity to eimeria species. Poultry science, 1993, Volume: 72, Issue:4 Topics: Animals; Body Weight; Chickens; Coccidiosis; Coccidiostats; Diet; Eimeria; Feces; Immunity; Male; Nicarbazin; Parasite Egg Count; Piperidines; Poultry Diseases; Quinazolines; Quinazolinones; Robenidine	1993
Mitigating the effects of halofuginone on skin strength by feeding L-proline to broiler chickens. Poultry science, 1995, Volume: 74, Issue:10 Topics: Animals; Body Weight; Chickens; Coccidiostats; Collagen; Female; Food, Fortified; Male; Piperidines; Proline; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength	1995
Inhibition of collagen synthesis and changes in skin morphology in murine graft-versus-host disease and tight skin mice: effect of halofuginone. The Journal of investigative dermatology, 1996, Volume: 106, Issue:1 Topics: Animals; Collagen; Disease Models, Animal; Fibrosis; Graft vs Host Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Osmolar Concentration; Piperidines; Quinazolines; Quinazolinones; Scleroderma, Localized; Skin	1996
Therapeutic efficacy of halofuginone and spiramycin treatment against Cryptosporidium serpentis (Apicomplexa: Cryptosporidiidae) infections in captive snakes. Parasitology research, 1996, Volume: 82, Issue:2 Topics: Animals; Coccidiostats; Cryptosporidium; Feces; Intestine, Large; Intestine, Small; Piperidines; Quinazolines; Quinazolinones; Snails; Spiramycin; Stomach	1996
Inhibition of collagen type I synthesis by skin fibroblasts of graft versus host disease and scleroderma patients: effect of halofuginone. Biochemical pharmacology, 1996, Oct-11, Volume: 52, Issue:7 Topics: Adult; Coccidiostats; Collagen; Dose-Response Relationship, Drug; Female; Fibroblasts; Graft vs Host Disease; Humans; Middle Aged; Piperidines; Quinazolines; Quinazolinones; Time Factors	1996
Reduction in pulmonary fibrosis in vivo by halofuginone. American journal of respiratory and critical care medicine, 1996, Volume: 154, Issue:4 Pt 1 Topics: Animals; Bleomycin; Collagen; Lung; Male; Piperidines; Pulmonary Fibrosis; Quinazolines; Quinazolinones; Rats; Rats, Inbred Strains	1996
Topically applied halofuginone, an inhibitor of collagen type I transcription, reduces peritendinous fibrous adhesions following surgery. Connective tissue research, 1996, Volume: 34, Issue:2 Topics: Animals; Chickens; Collagen; Gene Expression Regulation; Hydroxyproline; Inflammation; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Statistics, Nonparametric; Tendon Injuries; Tissue Adhesions	1996
Effect of halofuginone (Stenorol) on Chukar partridge (Alectoris chukar). Poultry science, 1996, Volume: 75, Issue:12 Topics: Animals; Coccidiostats; Dose-Response Relationship, Drug; Feeding Behavior; Growth; Piperidines; Poultry; Quinazolines; Quinazolinones; Weight Gain	1996
Inhibition of collagen synthesis, smooth muscle cell proliferation, and injury-induced intimal hyperplasia by halofuginone. Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:1 Topics: Animals; Arteries; Cattle; Cell Division; Cells, Cultured; Collagen; Humans; Hyperplasia; Muscle, Smooth, Vascular; Piperidines; Quinazolines; Quinazolinones; Rabbits; Tunica Intima	1997
Studies of resistance to anticoccidials in Eimeria field isolates and pure Eimeria strains. Veterinary parasitology, 1997, Volume: 69, Issue:1-2 Topics: Animals; Chickens; Coccidiosis; Coccidiostats; Drug Resistance; Drug Resistance, Multiple; Eimeria; Germany; Lactones; Male; Monensin; Nicarbazin; Nitriles; Piperidines; Poultry Diseases; Pyrans; Quinazolines; Quinazolinones; Robenidine; Triazines	1997
Halofuginone, a specific inhibitor of collagen type I synthesis, prevents dimethylnitrosamine-induced liver cirrhosis. Journal of hepatology, 1997, Volume: 27, Issue:2 Topics: Alkaline Phosphatase; Animals; Collagen; Dimethylnitrosamine; Gene Expression; In Situ Hybridization; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Experimental; Male; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley	1997
Inhibition of glomerular mesangial cell proliferation and extracellular matrix deposition by halofuginone. Kidney international, 1997, Volume: 52, Issue:6 Topics: Animals; Carbon Radioisotopes; Cell Division; Cells, Cultured; Collagen; Extracellular Matrix; Gene Expression; Glomerular Mesangium; Piperidines; Proline; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Sulfates; Tritium	1997
Residual activity of anticoccidial drugs in chickens after withdrawal of medicated feeds. Veterinary parasitology, 1998, Jan-31, Volume: 74, Issue:2-4 Topics: Amprolium; Animal Feed; Animals; Chickens; Coccidiosis; Coccidiostats; Eimeria tenella; Feces; Female; Lasalocid; Male; Monensin; Nicarbazin; Nitriles; Piperidines; Poultry Diseases; Pyrans; Quinazolines; Quinazolinones; Random Allocation; Triazines	1998
Halofuginone--an inhibitor of collagen type I synthesis--prevents postoperative formation of abdominal adhesions. Annals of surgery, 1998, Volume: 227, Issue:4 Topics: Abdomen; Animals; Collagen; Histocytochemistry; In Situ Hybridization; Piperidines; Postoperative Complications; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Tissue Adhesions	1998
Comparative efficacy of anticoccidials under the conditions of commercial broiler production and in battery trials. Veterinary parasitology, 1998, Apr-15, Volume: 76, Issue:3 Topics: Animal Husbandry; Animals; Chickens; Clopidol; Coccidiosis; Coccidiostats; Drug Resistance; Eimeria; Feces; Food Industry; Ionophores; Monensin; Nicarbazin; Piperidines; Poultry Diseases; Predictive Value of Tests; Pyrans; Quinazolines; Quinazolinones; Quinolones	1998
Redescription of Babesia equi Laveran, 1901 as Theileria equi Mehlhorn, Schein 1998. Parasitology research, 1998, Volume: 84, Issue:6 Topics: Animals; Antiprotozoal Agents; Arachnid Vectors; Babesia; Erythrocytes; Horse Diseases; Horses; Life Cycle Stages; Lymphocytes; Naphthoquinones; Piperidines; Quinazolines; Quinazolinones; Theileria; Theileriasis; Ticks	1998
Halofuginone inhibits neointimal formation of cultured rat aorta in a concentration-dependent fashion in vitro. Heart and vessels, 1998, Volume: 13, Issue:1 Topics: Animals; Aorta; Coccidiostats; Culture Techniques; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Tunica Intima	1998
Halofuginone, an inhibitor of collagen type I synthesis, prevents postoperative adhesion formation in the rat uterine horn model. American journal of obstetrics and gynecology, 1999, Volume: 180, Issue:3 Pt 1 Topics: Administration, Oral; Animals; Collagen; Female; Gene Expression; In Situ Hybridization; Injections, Intraperitoneal; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Uterine Diseases	1999
Inhibition of bladder carcinoma angiogenesis, stromal support, and tumor growth by halofuginone. Cancer research, 1999, Aug-15, Volume: 59, Issue:16 Topics: Animals; Antineoplastic Agents; Cell Division; Humans; Male; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Stromal Cells; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1999
Inhibition of matrix metalloproteinase-2 expression and bladder carcinoma metastasis by halofuginone. Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:8 Topics: Animals; Antineoplastic Agents; Carcinoma; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Gelatin; Humans; Laminin; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C3H; Neoplasm Invasiveness; Neoplasm Transplantation; Piperidines; Promoter Regions, Genetic; Proteoglycans; Quinazolines; Quinazolinones; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1999
Topical treatment of cutaneous chronic graft versus host disease with halofuginone: a novel inhibitor of collagen type I synthesis. Transplantation, 1999, Dec-15, Volume: 68, Issue:11 Topics: Administration, Topical; Adult; Animals; Collagen; Gene Expression; Graft vs Host Disease; Humans; Male; Neck; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rabbits; Range of Motion, Articular; Sclerosis; Skin; Skin Transplantation	1999
Use of epidermal growth factor and collagen synthesis inhibition as adjuvant to healing of ureteroureteral anastomosis. Journal of endourology, 2000, Volume: 14, Issue:2 Topics: Adjuvants, Pharmaceutic; Anastomosis, Surgical; Animals; Collagen; Drug Evaluation; Epidermal Growth Factor; Female; Piperidines; Quinazolines; Quinazolinones; Random Allocation; Swine; Ureter; Wound Healing	2000
Inhibition of neovascularization and tumor growth, and facilitation of wound repair, by halofuginone, an inhibitor of collagen type I synthesis. Neoplasia (New York, N.Y.), 1999, Volume: 1, Issue:4 Topics: Animals; Antineoplastic Agents; Collagen; Dose-Response Relationship, Drug; In Situ Hybridization; Kinetics; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Time Factors; Tumor Cells, Cultured; Wound Healing	1999
The effect of halofuginone, an inhibitor of collagen type i synthesis, on urethral stricture formation: in vivo and in vitro study in a rat model. The Journal of urology, 2000, Volume: 164, Issue:5 Topics: Animals; Collagen; Disease Models, Animal; Immunohistochemistry; In Situ Hybridization; Male; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Urethral Stricture	2000
Novel therapeutic strategies for leiomyomas: targeting growth factors and their receptors. Environmental health perspectives, 2000, Volume: 108 Suppl 5 Topics: Antineoplastic Agents; Blotting, Western; Chromatography, Liquid; Female; Growth Inhibitors; Growth Substances; Humans; Hysterectomy; Hysteroscopy; Immunohistochemistry; Interferon-alpha; Leiomyoma; Phenoxyacetates; Piperidines; Polymers; Protein Synthesis Inhibitors; Pyridones; Quinazolines; Quinazolinones; Receptors, Growth Factor; Uterine Neoplasms	2000
Halofuginone: a potent inhibitor of critical steps in angiogenesis progression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:15 Topics: Angiogenesis Inhibitors; Animals; Aorta; Capillaries; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibroblast Growth Factor 2; Matrix Metalloproteinase 2; Neovascularization, Physiologic; Piperidines; Quinazolines; Quinazolinones; Rats	2000
Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats. Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:2 Topics: Animals; Cell Division; Liver; Liver Cirrhosis; Male; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Thioacetamide	2001
Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone. Biochemical pharmacology, 2001, Nov-01, Volume: 62, Issue:9 Topics: Administration, Topical; Animals; Cell Division; Collagen; Disease Models, Animal; Fibrosis; Male; Mast Cells; Mice; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Skin	2001
Pharmacokinetics and tissue distribution of halofuginone (NSC 713205) in CD2F1 mice and Fischer 344 rats. Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:5 Topics: Animals; Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Male; Mice; Piperidines; Protein Binding; Quinazolines; Quinazolinones; Rats; Rats, Inbred F344; Tissue Distribution	2001
Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts. The Journal of investigative dermatology, 2002, Volume: 118, Issue:3 Topics: Animals; Cells, Cultured; Collagen; Collagen Type I; DNA-Binding Proteins; Fibroblasts; Gene Expression; Hyperplasia; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Piperidines; Quinazolines; Quinazolinones; Receptors, Transforming Growth Factor beta; Sclerosis; Signal Transduction; Skin; Skin Diseases; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta	2002
Growth inhibition of prostate cancer xenografts by halofuginone. The Prostate, 2002, May-01, Volume: 51, Issue:2 Topics: Adenocarcinoma; Administration, Oral; Androgens; Animals; Antineoplastic Agents; Apoptosis; Collagen Type I; Disease Progression; DNA, Neoplasm; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization; Injections, Intraperitoneal; Male; Mice; Mice, SCID; Necrosis; Neovascularization, Pathologic; Phenotype; Piperidines; Prostatic Neoplasms; Quinazolines; Quinazolinones	2002
Analysis of the effect of halofuginone on bleomycin-induced scleroderma. Rheumatology (Oxford, England), 2002, Volume: 41, Issue:5 Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Scleroderma, Systemic; Specific Pathogen-Free Organisms; Treatment Outcome	2002
Halofuginone does not reduce fibrosis in bleomycin-induced lung injury. Life sciences, 2002, Aug-23, Volume: 71, Issue:14 Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Bleomycin; Blotting, Northern; Bronchoalveolar Lavage Fluid; Cell Count; Collagen; Fibroblasts; Gene Expression Regulation; Hydroxyproline; Intubation, Intratracheal; Lung; Male; Piperidines; Pulmonary Fibrosis; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; RNA; Transforming Growth Factor beta	2002
Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats. Journal of hepatology, 2002, Volume: 37, Issue:3 Topics: Animals; Collagen Type I; Extracellular Matrix; Liver Cirrhosis; Liver Regeneration; Male; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Thioacetamide	2002
Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism. Arthritis and rheumatism, 2002, Volume: 46, Issue:10 Topics: Administration, Topical; Animals; Cells, Cultured; Collagen; Collagen Type I; Drug Synergism; Fibroblasts; Gene Expression; Male; Mice; Mice, Mutant Strains; Mitogens; Phosphorylation; Piperidines; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Quinazolines; Quinazolinones; RNA, Messenger; Scleroderma, Systemic; Transcription Factor AP-1; Transcriptional Activation; Transforming Growth Factor beta; Transforming Growth Factor beta1	2002
Effect of halofuginone on the development of tight skin (TSK) syndrome. Autoimmunity, 2002, Volume: 35, Issue:4 Topics: Animals; Animals, Newborn; Collagen; Disease Models, Animal; Fibrosis; Humans; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Scleroderma, Systemic; Skin Diseases	2002
A medical compound derived from herbs. Science (New York, N.Y.), 2003, Mar-28, Volume: 299, Issue:5615 Topics: Animals; Antineoplastic Agents; Coccidiosis; Coccidiostats; Drugs, Chinese Herbal; Humans; Phytotherapy; Piperidines; Poultry; Poultry Diseases; Quinazolines; Quinazolinones; Veterinary Drugs	2003
Development and validation of a method for the confirmation of halofuginone in chicken liver and eggs using electrospray tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, May-05, Volume: 788, Issue:1 Topics: Calibration; Coccidiostats; Eggs; Liver; Piperidines; Quinazolines; Quinazolinones; Spectrometry, Mass, Electrospray Ionization	2003
Treatment with halofuginone results in marked growth inhibition of a von Hippel-Lindau pheochromocytoma in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Sep-01, Volume: 9, Issue:10 Pt 1 Topics: Animals; Antineoplastic Agents; Cell Division; Collagen; Collagen Type I; Disease Progression; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Pheochromocytoma; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Temperature; Time Factors; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Vascular Endothelial Growth Factor A; von Hippel-Lindau Disease; Von Hippel-Lindau Tumor Suppressor Protein	2003
The use of halofuginone in limiting urethral stricture formation and recurrence: an experimental study in rabbits. The Journal of urology, 2003, Volume: 170, Issue:5 Topics: Administration, Oral; Animals; Electrocoagulation; Fibrosis; Male; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rabbits; Secondary Prevention; Urethra; Urethral Stricture	2003
Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. The Journal of biological chemistry, 2004, Apr-09, Volume: 279, Issue:15 Topics: Animals; Blotting, Northern; Blotting, Western; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Cells, Cultured; COS Cells; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Fibrosis; Gene Deletion; Genes, Reporter; Humans; Immunoblotting; MAP Kinase Signaling System; Mice; Mice, Inbred C3H; Microscopy, Confocal; Microscopy, Fluorescence; Piperidines; Plasmids; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Radiation Pneumonitis; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Time Factors; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1	2004
Halofuginone, an inhibitor of collagen synthesis by rat stellate cells, stimulates insulin-like growth factor binding protein-1 synthesis by hepatocytes. Journal of hepatology, 2004, Volume: 40, Issue:2 Topics: Animals; Cell Movement; Collagen Type I; Hepatocytes; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Male; Oligonucleotide Array Sequence Analysis; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Thioacetamide; Tissue Inhibitor of Metalloproteinase-2	2004
The effect of halofuginone, a specific inhibitor of collagen type 1 synthesis, in the prevention of esophageal strictures related to caustic injury. American journal of surgery, 2004, Volume: 187, Issue:2 Topics: Animals; Burns, Chemical; Caustics; Collagen Type I; Esophageal Stenosis; Esophagus; Fibrosis; Injections, Intraperitoneal; Male; Models, Animal; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Sodium Hydroxide	2004
Suppression of hepatocellular carcinoma growth in mice by the alkaloid coccidiostat halofuginone. European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:9 Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Coccidiostats; Drug Screening Assays, Antitumor; Humans; Interferon-gamma; Interleukin-2; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Piperidines; Quinazolines; Quinazolinones	2004
Ureteral replacement using small-intestinal submucosa and a collagen inhibitor in a porcine model. Journal of endourology, 2004, Volume: 18, Issue:5 Topics: Animals; Collagen Type I; Female; Intestinal Mucosa; Intestine, Small; Piperidines; Postoperative Complications; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Swine; Ureter; Ureteral Obstruction	2004
Determination of halofuginone in eggs by liquid chromatography/tandem mass spectrometry after cleanup with immunoaffinity chromatography. Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:16 Topics: Animals; Chickens; Chromatography, Affinity; Chromatography, High Pressure Liquid; Coccidiostats; Eggs; Piperidines; Quinazolines; Quinazolinones; Spectrometry, Mass, Electrospray Ionization	2004
Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of halofuginone in plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Oct-15, Volume: 810, Issue:1 Topics: Animals; Chromatography, Liquid; Coccidiostats; Dogs; Indicators and Reagents; Mass Spectrometry; Molecular Weight; Piperidines; Quinazolines; Quinazolinones; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2004
Halofuginone can worsen liver fibrosis in bile duct obstructed rats. Liver international : official journal of the International Association for the Study of the Liver, 2004, Volume: 24, Issue:5 Topics: Aminopyrine; Animals; Bile Ducts; Breath Tests; Cholestasis, Extrahepatic; Collagen Type I; Collagen Type III; Disease Models, Animal; Ligation; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Piperidines; Portal Pressure; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2004
Veterinary antiparasitic needs: met and unmet. Trends in parasitology, 2005, Volume: 21, Issue:1 Topics: Animals; Antiparasitic Agents; Cattle; Cattle Diseases; Drug Resistance; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Quinazolines; Quinazolinones; Treatment Outcome; Vaccination	2005
Halofuginone inhibits collagen deposition in fibrous capsules around implants. Annals of plastic surgery, 2005, Volume: 54, Issue:3 Topics: Animals; Collagen Type I; Colorimetry; Fibrosis; Male; Muscles; Piperidines; Prostheses and Implants; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Silicone Elastomers; Subcutaneous Tissue; Transforming Growth Factor beta	2005
Screening for the coccidiostats halofuginone and nicarbazin in egg and chicken muscle: development of an ELISA. Food additives and contaminants, 2005, Volume: 22, Issue:2 Topics: Animals; Antibodies; Carbanilides; Chickens; Coccidiostats; Cross Reactions; Drug Residues; Eggs; Enzyme-Linked Immunosorbent Assay; Food Contamination; Muscles; Nicarbazin; Piperidines; Quinazolines; Quinazolinones; Reproducibility of Results	2005
Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression. The Journal of urology, 2005, Volume: 174, Issue:4 Pt 2 Topics: Angiogenesis Inhibitors; Animals; Cell Line; Child, Preschool; Collagen; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Injections, Intraperitoneal; Kidney Neoplasms; Mice; Mice, Nude; Neovascularization, Pathologic; Piperidines; Proto-Oncogene Proteins c-met; Quinazolines; Quinazolinones; Receptor, ErbB-2; Transplantation, Heterologous; Wilms Tumor; WT1 Proteins	2005
Prevention of esophageal strictures in a caustic burn model using halofuginone, an inhibitor of collagen type I synthesis. The Laryngoscope, 2005, Volume: 115, Issue:9 Topics: Animals; Burns, Chemical; Caustics; Collagen Type I; Esophageal Stenosis; In Vitro Techniques; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Radiography; Rats; Sodium Hydroxide; Transforming Growth Factor beta; Wound Healing	2005
Halofuginone inhibits tumor growth in the polyoma middle T antigen mouse via a thrombospondin-1 independent mechanism. Cancer biology & therapy, 2006, Volume: 5, Issue:2 Topics: Animals; Antigens, Viral, Tumor; Antineoplastic Agents; Breast Neoplasms; Collagen Type I; Mice; Mice, Transgenic; Neovascularization, Pathologic; Piperidines; Polyomavirus; Quinazolines; Quinazolinones; Smad2 Protein; Smad3 Protein; Thrombospondin 1; Transforming Growth Factor beta; Tumor Burden	2006
Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB. The Journal of biological chemistry, 2006, Jun-02, Volume: 281, Issue:22 Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Cells, Cultured; Collagenases; Enzyme Induction; Hepatocytes; Liver Cirrhosis; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Piperidines; Quinazolines; Quinazolinones; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction	2006
Inhibition of rat renal fibroblast proliferation by halofuginone. Nephron. Experimental nephrology, 2006, Volume: 104, Issue:1 Topics: Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Kidney Medulla; Male; Matrix Metalloproteinase Inhibitors; Piperidines; Platelet-Derived Growth Factor; Quinazolines; Quinazolinones; Rats; Rats, Wistar	2006
Halofuginone prevents subglottic stenosis in a canine model. The Annals of otology, rhinology, and laryngology, 2006, Volume: 115, Issue:5 Topics: Animals; Cells, Cultured; Disease Models, Animal; Dogs; Fibroblasts; Follow-Up Studies; Humans; In Vitro Techniques; Laryngostenosis; Mitomycin; Nucleic Acid Synthesis Inhibitors; Piperidines; Protein Synthesis Inhibitors; Quinazolines; Quinazolinones; Treatment Outcome	2006
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. Neoplasia (New York, N.Y.), 2006, Volume: 8, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Matrix Metalloproteinases, Membrane-Associated; Neoplasm Metastasis; Piperidines; Quinazolines; Quinazolinones; Rats; Rats, Inbred F344	2006
Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells. Journal of leukocyte biology, 2006, Volume: 80, Issue:2 Topics: Apoptosis; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Humans; Lymphocyte Activation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Quinazolines; Quinazolinones; Signal Transduction; T-Lymphocytes	2006
Synthesis and comparison of antimalarial activity of febrifugine derivatives including halofuginone. Medicinal chemistry (Shariqah (United Arab Emirates)), 2009, Volume: 5, Issue:3 Topics: Animals; Antimalarials; Benzoates; Cell Line; Piperidines; Plasmodium falciparum; Quinazolines; Quinazolinones	2009
Dihydroxylation of vinyl sulfones: stereoselective synthesis of (+)- and (-)-febrifugine and halofuginone. The Journal of organic chemistry, 2010, Jan-15, Volume: 75, Issue:2 Topics: Catalysis; Hydroxylation; Molecular Structure; Piperidines; Quinazolines; Quinazolinones; Stereoisomerism; Sulfones	2010
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nature chemical biology, 2012, Feb-12, Volume: 8, Issue:3 Topics: Amino Acyl-tRNA Synthetases; Animals; Cell Differentiation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mice; Mice, Inbred C57BL; Piperidines; Quinazolines; Quinazolinones; Structure-Activity Relationship; Th17 Cells	2012
ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase. Nature, 2013, Feb-07, Volume: 494, Issue:7435 Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Antimalarials; Binding Sites; Crystallography, X-Ray; Herbal Medicine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Medicine, Chinese Traditional; Models, Molecular; Piperidines; Proline; Quinazolines; Quinazolinones; RNA, Transfer	2013
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Science translational medicine, 2015, May-20, Volume: 7, Issue:288 Topics: Amino Acyl-tRNA Synthetases; Animals; Antimalarials; Computer-Aided Design; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Resistance; Enzyme Inhibitors; Erythrocytes; Liver; Malaria, Falciparum; Mice; Models, Molecular; Molecular Structure; Molecular Targeted Therapy; Piperidines; Plasmodium falciparum; Protozoan Proteins; Quinazolines; Quinazolinones; Structure-Activity Relationship; Time Factors	2015