quinazolines has been researched along with gw2974 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ajiki, T; Digiovanni, J; Kawamoto, T; Kiguchi, K; Ruffino, L | 1 |
| Ajose-Adeogun, A; Coley, HM; Modjtahedi, H; Shotton, CF; Thomas, H | 1 |
| Berger, M; Lipton, A; Planas-Silva, MD; Viallet, J; Witkoski, A; Witters, LM | 1 |
| Bacus, SS; Hill, JE; Lyass, L; Pry, K; Seger, R; Smith, B; Spector, NL; Trusk, P; Xia, W; Yarden, Y | 1 |
| Chen, X; Li, N; Newman, RA; Sood, S; Sun, Z; Yang, CS; Yang, P | 1 |
| Ge, HB; Li, P; Sun, Z | 1 |
| Bacus, SS; Lyass, L; Pry, KJ; Shell, SA; Trusk, PB; Wappel, RL | 1 |
| Agarwal, S; Christensen, JG; Digiovanna, MP; Harris, LN; Kolmakova, J; Rimm, DL; Stern, DF; Zerillo, C | 1 |
| Greufe, S; Hayward, R; Hydock, DS; Schneider, CM; Wonders, KY | 1 |
| Altieri, V; De Placido, S; Di Carlo, A; Di Lorenzo, G; Ferro, M; Giordano, A; Macchia, V; Mariano, A; Mazzarella, C; Terracciano, D | 1 |
| Chang, HC; Connolly, K; DiGiovanni, J; Kiguchi, K; Kitamura, T; Moore, T; Ruffino, L; Rumi, M; Treece, D | 1 |
| Badinloo, M; Hajializadeh, Z; Jangi-Aghdam, H; Pooraboli, I; Rajabalian, S | 1 |
| Chen, JJ; Chen, ZS; Patel, A; Singh, S; Sodani, K; Sun, YL; Talele, TT; Tiwari, AK; Xiao, ZJ | 1 |
| Cui, K; Hao, A; Jin, G; Liu, Q; Nie, F; Wang, L; Wong, ST; Yao, L; Zhao, H | 1 |
14 other study(ies) available for quinazolines and gw2974
| Article | Year |
|---|---|
Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Blotting, Western; Body Weight; Carcinoma; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; ErbB Receptors; Gallbladder; Gallbladder Neoplasms; Gefitinib; Humans; In Situ Nick-End Labeling; MAP Kinase Signaling System; Mice; Mice, Transgenic; Microscopy, Fluorescence; Neoplasms, Experimental; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Receptor, ErbB-2; Tolonium Chloride | 2005 |
Receptor tyrosine kinase (RTK) inhibition is effective in chemosensitising EGFR-expressing drug resistant human ovarian cancer cell lines when used in combination with cytotoxic agents.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; ErbB Receptors; Female; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Neoplasm Proteins; Ovarian Neoplasms; Paclitaxel; Quinazolines; Receptor Protein-Tyrosine Kinases; Survivin | 2006 |
Synergistic inhibition of breast cancer cell lines with a dual inhibitor of EGFR-HER-2/neu and a Bcl-2 inhibitor.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzopyrans; Breast Neoplasms; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors; Humans; Indoles; Lapatinib; Nitriles; Prognosis; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Quinazolines; Receptor, ErbB-2 | 2007 |
Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Apoptosis; Calcium; Cells, Cultured; Enzyme Activation; ErbB Receptors; Fatty Acids; Female; Gene Expression; Humans; Models, Biological; Multienzyme Complexes; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2 | 2007 |
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Dinoprostone; ErbB Receptors; Humans; Male; Mouth Mucosa; Mouth Neoplasms; Quinazolines; Receptor, ErbB-2 | 2008 |
[Inhibiting effects of GW2974 on DMBA-induced hamster buccal pouch carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cricetinae; Disease Models, Animal; Male; Mouth Neoplasms; Protein-Tyrosine Kinases; Quinazolines | 2007 |
Activation of AMPK is necessary for killing cancer cells and sparing cardiac cells.
Topics: AMP-Activated Protein Kinases; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Enzyme Activation; ErbB Receptors; Genes, p53; Humans; Multienzyme Complexes; Mutation; Myocytes, Cardiac; Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Receptor, ErbB-2; Trastuzumab | 2008 |
Association of constitutively activated hepatocyte growth factor receptor (Met) with resistance to a dual EGFR/Her2 inhibitor in non-small-cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Quinazolines; Receptor, ErbB-2; Receptors, Growth Factor; Wound Healing | 2009 |
Endurance exercise training preserves cardiac function in rats receiving doxorubicin and the HER-2 inhibitor GW2974.
Topics: Animals; Antineoplastic Agents; Apoptosis; Body Weight; Caspase 3; Caspase 8; Doxorubicin; Exercise Therapy; Female; Heart; Heart Ventricles; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Quinazolines; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left; Ventricular Pressure | 2009 |
Effects of the ErbB1/ErbB2 kinase inhibitor GW2974 on androgen-independent prostate cancer PC-3 cell line growth and NSE, chromogranin A and osteopontin content.
Topics: Androgens; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Carcinoma; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Chromogranin A; Cytosol; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Male; Osteopontin; Prostatic Neoplasms; Quinazolines; Receptor, ErbB-2 | 2010 |
Dual inhibition of both the epidermal growth factor receptor and erbB2 effectively inhibits the promotion of skin tumors during two-stage carcinogenesis.
Topics: Algorithms; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Progression; Drug Evaluation, Preclinical; ErbB Receptors; Gene Expression Regulation, Neoplastic; Mice; Mice, Transgenic; Neoplasms, Glandular and Epithelial; Protein Kinase Inhibitors; Quinazolines; Receptor, ErbB-2; Skin Neoplasms; Treatment Outcome | 2010 |
Establishment, characterization, and drug sensitivity of a new Ewing sarcoma cell line (SS-ES-1).
Topics: Adolescent; Antineoplastic Agents; Biomarkers, Tumor; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Female; Humans; Neoplasm Proteins; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; Quinazolines; RNA-Binding Protein EWS; Sarcoma, Ewing; Soft Tissue Neoplasms; Tamoxifen; Tyrphostins | 2010 |
GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Models, Molecular; Neoplasm Proteins; Quinazolines; Receptor, ErbB-2; Sulfones | 2012 |
Differential effects of low- and high-dose GW2974, a dual epidermal growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; ErbB Receptors; Glioblastoma; Humans; Male; Mice; Mice, SCID; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Protein Array Analysis; Quinazolines; Receptor, ErbB-2; Xenograft Model Antitumor Assays | 2013 |