Page last updated: 2024-08-21

quinazolines and guanosine triphosphate

quinazolines has been researched along with guanosine triphosphate in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's4 (28.57)29.6817
2010's3 (21.43)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Mansour, JM; Mansour, TE1
Hamel, E; Hesson, DP; Jiang, JB; Kang, GJ; Lin, CM; Luduena, RF; Roach, MC1
Chi, DM; Hamel, E; Ho, HH; Shahrik, LK1
Cazin, L; Mei, YA; Vaudry, H1
Liang, NC; Liu, XG1
Marcoux, N; Vuori, K1
Cai, K; Enomoto, A; Hosoi, Y; Li, Z; Matsumoto, Y; Miyagawa, K; Morita, A; Nakagawa, K; Tanno, Y1
Emri, Z; Héja, L; Kardos, J; Lasztóczi, B; Nyikos, L; Simon, A; Szárics, E1
Birtwistle, M; Calder, M; Gilbert, D; Grindlay, J; Kholodenko, B; Kolch, W; Orton, R; Pitt, A; Sturm, OE; Vyshemirsky, V1
Hamburger, AW; Lee, Y; Mitchell, BS; Nguyen, le XT; Sunwoo, JB; Urbani, L; Utz, PJ1
Chao, CY; Chen, WS; Chen, YJ; Chiu, HC; Hsieh, BY; Huang, YA; Hwang, E; Kao, PY1
Chen, J; Li, L; Liu, J; Mai, R; Zhao, H1
Chu, Y; Dai, J; He, Y; Ju, S; Li, J; Li, Q; Lin, Q; Peng, L; Rui, R1
Chen, J; Chen, T; Li, L; Lin, L; Liu, J; Mai, R; Peng, X; Shi, J; Yan, J; Zhao, H1

Other Studies

14 other study(ies) available for quinazolines and guanosine triphosphate

ArticleYear
Effect of some phosphodiesterase inhibitors on adenylate cyclase from the liver fluke, Fasciola hepatica.
    Biochemical pharmacology, 1979, Jun-15, Volume: 28, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Etazolate; Fasciola hepatica; Guanosine Triphosphate; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Quinazolines; Serotonin

1979
Investigation of the mechanism of the interaction of tubulin with derivatives of 2-styrylquinazolin-4(3H)-one.
    Molecular pharmacology, 1991, Volume: 40, Issue:5

    Topics: Antineoplastic Agents; Binding Sites; Colchicine; Guanosine Triphosphate; Quinazolines; Styrenes; Tropolone; Tubulin

1991
Tubulin-dependent hydrolysis of guanosine triphosphate as a screening test to identify new antitubulin compounds with potential as antimitotic agents: application to carbamates of aromatic amines.
    Cancer research, 1989, Mar-15, Volume: 49, Issue:6

    Topics: Antineoplastic Agents; Benzimidazoles; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Mitosis; Nocodazole; Pyrazines; Quinazolines; Structure-Activity Relationship; Tubulin Modulators

1989
Inhibitory effect of adenosine on electrical activity of frog melanotrophs mediated through A1 purinergic receptors.
    The Journal of physiology, 1994, Dec-01, Volume: 481 ( Pt 2)

    Topics: Action Potentials; Adenosine; alpha-MSH; Animals; Cells, Cultured; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Membrane Potentials; Patch-Clamp Techniques; Pertussis Toxin; Phenylisopropyladenosine; Pituitary Gland; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Quinazolines; Rana ridibunda; Tachyphylaxis; Theophylline; Triazoles; Virulence Factors, Bordetella

1994
Inhibitory effect and its kinetic analysis of tyrphostin AG1478 on recombinant human protein kinase CK2 holoenzyme.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:6

    Topics: Casein Kinase II; Caseins; DNA-Binding Proteins; Enzyme Inhibitors; Guanosine Triphosphate; Holoenzymes; Humans; Kinetics; Protein Serine-Threonine Kinases; Quinazolines; Recombinant Proteins; Tyrphostins

2002
EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2.
    Oncogene, 2003, Sep-04, Volume: 22, Issue:38

    Topics: Actins; Animals; Cell Adhesion; Cells, Cultured; COS Cells; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Guanosine Triphosphate; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Oncogene Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-vav; Quinazolines; rac GTP-Binding Proteins; Tyrosine; Tyrphostins

2003
Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.
    Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2

    Topics: Androstadienes; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanosine Triphosphate; Humans; Immunoblotting; Immunoprecipitation; Infrared Rays; Intracellular Signaling Peptides and Proteins; Kinetics; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; Radiation, Ionizing; Signal Transduction; src-Family Kinases; Temperature; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Wortmannin; X-Rays

2006
Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: involvement of a metabotropic glutamate receptor.
    Neurochemistry international, 2006, Volume: 49, Issue:1

    Topics: Age Factors; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cell Membrane; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; Male; Nerve Net; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Protein Subunits; Pyramidal Cells; Quinazolines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission

2006
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier.
    Science signaling, 2010, Dec-21, Volume: 3, Issue:153

    Topics: Animals; Butadienes; Cell Membrane; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Flow Cytometry; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoblotting; Immunoprecipitation; Indoles; Kinetics; MAP Kinase Kinase Kinases; Metabolic Networks and Pathways; Mice; Models, Theoretical; NIH 3T3 Cells; Nitriles; Phosphorylation; Quinazolines; ras Proteins; Signal Transduction

2010
Regulation of ribosomal RNA synthesis in T cells: requirement for GTP and Ebp1.
    Blood, 2015, Apr-16, Volume: 125, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Blotting, Western; Cell Proliferation; Cells, Cultured; DNA, Ribosomal; Gene Expression; Guanosine Triphosphate; HEK293 Cells; Humans; Jurkat Cells; Keratin-20; Lymphocyte Activation; Mutation; Mycophenolic Acid; Phosphorylation; Pol1 Transcription Initiation Complex Proteins; Proliferating Cell Nuclear Antigen; Promoter Regions, Genetic; Protein Binding; Protein Kinase C-delta; Pyrroles; Quinazolines; RNA Interference; RNA Polymerase I; RNA-Binding Proteins; RNA, Ribosomal; T-Lymphocytes

2015
Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons.
    Scientific reports, 2017, 02-13, Volume: 7

    Topics: alpha Karyopherins; Animals; beta Karyopherins; Cell Cycle Proteins; Centrosome; Guanosine Triphosphate; Hippocampus; Mice, Inbred C57BL; Microtubule-Associated Proteins; Microtubules; Models, Biological; Morphogenesis; Neurites; Neurons; Nuclear Proteins; Protein Binding; Protein Transport; Quinazolines; ran GTP-Binding Protein

2017
Discovery of ARS-1620 analogs as KRas G12C inhibitors with high in vivo antitumor activity.
    Bioorganic chemistry, 2022, Volume: 121

    Topics: Animals; Guanosine Triphosphate; Humans; Mice; Mice, Nude; Mutation; Neoplasms; Piperazines; Proto-Oncogene Proteins p21(ras); Quinazolines

2022
Effects of Ran-GTP/importin β inhibition on the meiotic division of porcine oocytes.
    Histochemistry and cell biology, 2022, Volume: 158, Issue:6

    Topics: Animals; beta Karyopherins; Guanosine Triphosphate; Mammals; Quinazolines; Signal Transduction; Swine

2022
Discovery of novel Quinazoline-based KRAS G12C inhibitors as potential anticancer agents.
    Bioorganic & medicinal chemistry, 2022, 10-01, Volume: 71

    Topics: Animals; Antineoplastic Agents; Guanosine Triphosphate; Humans; Mice; Mice, Nude; Mutation; Neoplasms; Proto-Oncogene Proteins p21(ras); Quinazolines

2022