quinazolines has been researched along with glycine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 10 (45.45) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Calligaro, DO; Lodge, D; McQuaid, LA; Mitch, CH; O'Malley, PJ; Ornstein, PL; Schoepp, DD; Smith, EC; South, KK; True, RA | 1 |
| Mantle, PG; Penn, J; Purcell, M | 1 |
| Kaneko, S; Koyanagi, T; Kumamoto, Y; Maru, A; Nishizawa, O; Orikasa, S; Togashi, M; Tsuchida, S; Tsukamoto, T; Yachiku, S | 1 |
| Allegra, CJ; Baram, J; Drake, JC; Hoang, K; Yeh, GC | 1 |
| Benkovic, SJ; Boger, DL; Cai, H; Greasley, SE; Wilson, IA; Yamashita, MM | 1 |
| Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ | 1 |
| Baek, DJ; Ha, JR; Oh, SW | 1 |
| Carlà, V; Catarzi, D; Colotta, V; Costagli, C; Filacchioni, G; Galli, A; Varano, F | 1 |
| Avendaño, C; Corzo-Suárez, R; Espada, M; Gago, F; García-Granda, S; Martín-Santamaría, S; Rzepa, HS | 1 |
| Becker, JW; Cameron, PM; Fitzgerald, CE; O'Keefe, SJ; Patel, SB; Pikounis, VB; Scapin, G; Zaller, D | 1 |
| Chalothorn, D; Faber, JE; Jackson, LF; Lee, DC; Zhang, H | 1 |
| Jin, Y; Qiao, QA; Wang, M; Yang, C; Zhang, Z | 1 |
| Higashiyama, S; Itoh, M; Joh, T; Kataoka, H; Nakao, H; Ohhara, H; Ohshima, T; Sasaki, M; Tanida, S; Watanabe, K | 1 |
| Chattopadhyay, S; Goldman, ID; Krupenko, N; Krupenko, SA; Zhao, R | 1 |
| Iwasaki, T; Kimura, H; Kitada, S; Maekura, R; Mori, M; Naka, N; Nakagawa, M; Nakazawa, Y; Namba, Y; Niinaka, M; Okada, T; Yano, Y; Yokota, S | 1 |
| Alzani, R; Ciomei, M; Degrassi, A; Fanti, S; Giusti, AM; Nanni, C; Patton, V; Pesenti, E; Russo, M; Texido, G | 1 |
| Xiao, X; Xu, TL; Zhu, MX | 1 |
| Asara, JM; Choi, JH; Cui, H; Ding, HF; Ding, J; Dong, Z; Huang, S; Li, T; Wang, X; Yang, L; Zha, Y; Zhao, E | 1 |
| Alpini, G; DeMorrow, S; Frampton, G; Galindo, C; McMillin, M; Standeford, H; Thompson, M; Whittington, E | 1 |
| Arimura-Omori, M; Hamada, N; Harada, E; Ikeda-Harada, C; Mikumo, H; Nakanishi, Y; Ogata-Suetsugu, S; Suzuki, K; Yanagihara, T; Yokoyama, T | 1 |
| Alam, KA; Engh, RA; Gani, OASBM | 1 |
| Anderman, MF; Bhargava, D; Boccuzzi, L; de Miguel, FJ; Doroshow, JH; Durkin, ME; Lowy, DR; Papageorge, AG; Politi, K; Qian, X; Tripathi, BK; Walters, KJ; Wang, D | 1 |
1 trial(s) available for quinazolines and glycine
| Article | Year |
|---|---|
[A double-blind trial on the effect of bunazosin hydrochloride for the symptoms of benign prostatic hypertrophy].
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Alanine; Chi-Square Distribution; Double-Blind Method; Drug Combinations; Glutamates; Glycine; Humans; Japan; Male; Middle Aged; Prostatic Hyperplasia; Quinazolines; Urination; Urination Disorders | 1990 |
21 other study(ies) available for quinazolines and glycine
| Article | Year |
|---|---|
Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glycine; Ibotenic Acid; Male; Quinazolines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship | 1992 |
Biosynthesis of glyantrypine by Aspergillus clavatus.
Topics: Alkaloids; Amino Acids; Aspergillus; Glycine; ortho-Aminobenzoates; Quinazolines; Tryptophan | 1992 |
Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
Topics: Acyltransferases; Antineoplastic Agents; Breast Neoplasms; Carbon Radioisotopes; Cell Line; Female; Floxuridine; Folic Acid; Glycine; Humans; Hydroxymethyl and Formyl Transferases; Kinetics; Methotrexate; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Polyglutamic Acid; Purines; Quinazolines; Trimetrexate | 1987 |
New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.
Topics: Binding, Competitive; Carbon Isotopes; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli; Glutamates; Glycine; Hydroxymethyl and Formyl Transferases; Ligands; Nuclear Magnetic Resonance, Biomolecular; Phosphoribosylglycinamide Formyltransferase; Protein Binding; Quinazolines; Ribonucleotides; Substrate Specificity | 1999 |
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection | 2000 |
In vivo antitumor efficacy of CW252053, a folate-based thymidylate synthase inhibitor.
Topics: Animals; Antineoplastic Agents; Female; Folic Acid Antagonists; Glycine; Lymphoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Quinazolines; Survival Analysis; Thymidylate Synthase; Tumor Cells, Cultured | 2001 |
Synthesis and biological evaluation of a new set of pyrazolo[1,5-c]quinazoline-2-carboxylates as novel excitatory amino acid antagonists.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Mice; Quinazolines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2002 |
Diastereoselective reactions in glycine templates containing an ent-ardeemin fragment.
Topics: Alkylation; Chemistry, Organic; Crystallography, X-Ray; Glycine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Pyrazines; Pyrimidinones; Quinazolines; Stereoisomerism | 2002 |
Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Enzyme Inhibitors; Glycine; Imidazoles; Inhibitory Concentration 50; Kinetics; Mice; Mitogen-Activated Protein Kinase 14; Mitogen-Activated Protein Kinases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Pyridazines; Pyridines; Pyrimidines; Quinazolines; Sequence Homology, Amino Acid | 2003 |
Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anthracenes; Aorta, Thoracic; Bacterial Proteins; Benzopyrans; Butadienes; Catheterization; Cell Division; Dipeptides; ErbB Receptors; Flavonoids; Glycine; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Organ Culture Techniques; Phenylephrine; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Thrombin; Tyrphostins | 2004 |
A quantum chemical study on the mechanism of glycinamide ribonucleotide transformylase inhibitor: 10-Formyl-5,8,10-trideazafolic acid.
Topics: Catalysis; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Glutamates; Glycine; Models, Chemical; Molecular Structure; Phosphoribosylglycinamide Formyltransferase; Quantum Theory; Quinazolines; Ribonucleotides; Stereoisomerism | 2005 |
Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.
Topics: ADAM Proteins; Cell Line, Tumor; Cell Proliferation; DNA; Enzyme Activation; ErbB Receptors; Flavonoids; Glycine; Helicobacter pylori; Humans; Hydroxamic Acids; Interleukin-8; MAP Kinase Kinase 1; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Transcriptional Activation; Tyrphostins | 2005 |
The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line.
Topics: Amino Acid Substitution; Antineoplastic Agents; Arginine; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Glutamates; Glycine; Guanine; Humans; Leucovorin; Methotrexate; Mutation; Pemetrexed; Phosphoribosylglycinamide Formyltransferase; Purines; Pyrimidines; Quinazolines; Receptors, Cell Surface; Thiophenes; Thymidylate Synthase | 2006 |
[A case of lung adenocarcinoma effectively treated with sivelestat and corcicosteroid for drug-induced lung disease due to gefitinib].
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Gefitinib; Glycine; Humans; Lung Diseases; Lung Neoplasms; Male; Prednisolone; Quinazolines; Serine Proteinase Inhibitors; Sulfonamides | 2008 |
Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging.
Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Antineoplastic Agents; Aspartic Acid; Cyclin-Dependent Kinases; Diagnostic Imaging; Disease Models, Animal; Drug Evaluation, Preclinical; Genes, ras; Glycine; Humans; Lung Neoplasms; Mice; Mice, Transgenic; Mutant Proteins; Pyrazoles; Quinazolines; Treatment Outcome | 2010 |
2-Guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type γ-aminobutyric acid receptors.
Topics: Acetylcholine; Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agents; GABA Agents; gamma-Aminobutyric Acid; Glycine; Guanidines; Hippocampus; Humans; In Vitro Techniques; Mutation; Neurons; Protein Subunits; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2013 |
The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation.
Topics: Animals; Autophagy; Azepines; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Epigenomics; Glycine; HeLa Cells; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Mice; Microtubule-Associated Proteins; Quinazolines; Ribosomes; Serine; Transcription, Genetic | 2013 |
Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline.
Topics: Animals; Azoxymethane; Benzamides; Body Temperature; Body Weight; Carcinogens; Chemokine CCL2; Disease Models, Animal; Enzyme Inhibitors; Glycine; Hepatic Encephalopathy; Liver; Male; Mice; Mice, Inbred C57BL; Microglia; Nervous System Diseases; Quinazolines; Signal Transduction; Time Factors; Up-Regulation | 2014 |
Neutrophil elastase inhibitor sivelestat ameliorates gefitinib-naphthalene-induced acute pneumonitis in mice.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Female; Gefitinib; Glycine; Humans; Kaplan-Meier Estimate; Leukocyte Count; Leukocyte Elastase; Lung; Mice, Inbred C57BL; Naphthalenes; Neutrophils; Pneumonia; Quinazolines; Serine Proteinase Inhibitors; Sulfonamides; Weight Loss | 2017 |
Inhibitor binding to mutants of protein kinase A with GGGxxG and GxGxxA glycine-rich loop motifs.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Substitution; Binding Sites; Cyclic AMP-Dependent Protein Kinases; Glycine; Mutation; Protein Kinase Inhibitors; Quinazolines; Staurosporine; Surface Plasmon Resonance | 2021 |
Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein.
Topics: Animals; Antineoplastic Agents; Benzodioxoles; Boron Compounds; Cell Line, Tumor; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; Gene Knockout Techniques; Glycine; GTPase-Activating Proteins; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; Lung Neoplasms; Mice; Mutagenesis, Site-Directed; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Stability; Proto-Oncogene Proteins p21(ras); Quinazolines; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2021 |