Page last updated: 2024-08-21

quinazolines and genistein

quinazolines has been researched along with genistein in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (16.22)18.2507
2000's28 (75.68)29.6817
2010's3 (8.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hollenberg, MD; Zheng, XL1
Klein, JM; McCarthy, TA1
Berthelemy, M; Dangles, V; Féménia, F; Lainé, V; Le Rhun, D; Levy, D; Poupon, MF; Schwartz-Cornil, I1
DeWild, LJ; Klein, JM; McCarthy, TA1
Akhand, AA; Kato, M; Kurokawa, K; Liu, W; Miyata, T; Nakashima, I; Uchida, K; Yokoyama, I1
Polk, DB; Tong, W1
Liu, R; Liu, XP; Trieu, VN; Uckun, FM1
Braun, L; Chase, CC; Frew, T; Hurley, DJ; Rowland, RR; Shaw, AM1
DeMattia, JA; Khoshyomn, S; Naraghi, S; Vane, DW1
Ghosh, S; Liu, XP; Myers, DE; Sudbeck, EA; Uckun, FM; Zheng, Y1
Berk, BC; Chen, K; Keaney, JF; Vita, JA1
Chavis, P; Westbrook, G1
Avkiran, M; Hearse, DJ; Snabaitis, AK1
Choi, BH; Choi, JS; Hahn, SJ; Jo, YH; Kim, MS; Min, DS; Rhie, DJ; Yoon, SH1
Park, SY; Seol, DW1
Baumgarten, CM; Ren, Z1
Long, HC; Wang, G; Wang, ZH; Wang, ZL; Xiao, BR1
Akhtar, S; Benter, IF; Yousif, MH1
Akhtar, S; Benboubetra, M; Benter, IF; Griffiths, SM; Yousif, MH1
Chicoine, LG; English, BK; Liu, Y; Nelin, LD; Reber, KM; Young, TL1
Halgunset, J; Larsson, E; Skogseth, H3
Davis, DA; Hussain, M; Li, Y; Sarkar, FH; Sarkar, SH1
Awooda, I; Barhoumi, R; Burghardt, RC; Mouneimne, Y; Safe, S1
Halgunset, J; Holt, RU; Larsson, E; Skogseth, H1
Boron, WF; Bouyer, P; Zhou, Y1
Follestad, T; Halgunset, J; Larsson, E; Skogseth, H1
Ben-Bassat, H; Klein, BY; Laufer, N; Mishani, E; Rojansky, N; Shushan, A1
Abbruzzese, J; Ali, IF; Ali, S; El-Rayes, BF; Philip, PA; Sarkar, FH1
Cheon, H; Cho, S; Kim, HJ; Kim, HS; Lee, JY; Sohn, J; Won, NH; Woo, YS1
Linsdell, P; McDonald, TF; Missan, S1
Akingbemi, BT; Braden, TD; Coleman, ES; Hancock, KD; Kemppainen, BW; Morrison, EE; Tao, YX1
Ali, S; Gadgeel, SM; Philip, PA; Sarkar, FH; Wozniak, A1
Ikejima, T; Onodera, S; Tashino, S; Wu, LJ; Yang, J1
Adhikary, S; Davey, RA; Garver, J; Johnson, L; Kolokoltsov, AA; Vela, EM1
Cheng, H; De Luo, B; Liu, ZG; Ren, Y; Zhang, YF; Zhu, H1

Reviews

1 review(s) available for quinazolines and genistein

ArticleYear
Tyrosine kinase inhibitors against EGF receptor-positive malignancies.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 166

    Topics: Adenocarcinoma; Amides; Aniline Compounds; Animals; Antineoplastic Agents; Breast Neoplasms; Drug Design; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; Humans; Leukemia; Macaca fascicularis; Mice; Mice, Inbred BALB C; Mice, SCID; Models, Molecular; Molecular Structure; Neoplasm Proteins; Neoplasms; Nitriles; Protein Conformation; Protein Structure, Tertiary; Quinazolines; Recombinant Fusion Proteins; Sequence Alignment; Species Specificity; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2001

Other Studies

36 other study(ies) available for quinazolines and genistein

ArticleYear
Tyrosine kinase inhibitor-sensitive contractile action of ethanol in gastric smooth muscle: comparison with the action of epidermal growth factor.
    Proceedings of the Association of American Physicians, 1997, Volume: 109, Issue:1

    Topics: 1-Propanol; Animals; Calcium; Catechols; Cyclohexanones; Enzyme Inhibitors; Epidermal Growth Factor; Ethanol; Fomepizole; Genistein; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Male; Maleimides; Methanol; Muscle Contraction; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyrazoles; Quinazolines; Signal Transduction; Stomach; Tyrphostins

1997
Inhibition of tyrosine kinase activity decreases expression of surfactant protein A in a human lung adenocarcinoma cell line independent of epidermal growth factor receptor.
    Biochimica et biophysica acta, 1997, Mar-01, Volume: 1355, Issue:3

    Topics: Benzylidene Compounds; Binding, Competitive; Blotting, Northern; Blotting, Western; Cell Survival; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Isoflavones; Lung; Lung Neoplasms; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Quinazolines; RNA, Messenger; Tumor Cells, Cultured; Tyrphostins

1997
Two- and three-dimensional cell structures govern epidermal growth factor survival function in human bladder carcinoma cell lines.
    Cancer research, 1997, Aug-15, Volume: 57, Issue:16

    Topics: Apoptosis; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Isoflavones; Neoplasm Proteins; Nitriles; Protein-Tyrosine Kinases; Quinazolines; Spheroids, Cellular; Time Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrphostins; Up-Regulation; Urinary Bladder Neoplasms

1997
Effect of tyrosine kinase inhibition on surfactant protein A gene expression during human lung development.
    The American journal of physiology, 1998, Volume: 274, Issue:4 Pt 1

    Topics: Embryonic and Fetal Development; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Genistein; Homeostasis; Humans; Lung; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Quinazolines; RNA, Messenger; Tyrosine; Tyrphostins

1998
4-hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition.
    Journal of cell science, 1999, Volume: 112 ( Pt 14)

    Topics: Aldehydes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cross-Linking Reagents; Enzyme Activation; ErbB Receptors; Genistein; Humans; Lipid Peroxidation; Oxidative Stress; Phosphoproteins; Phosphorylation; Quinazolines; Signal Transduction; Tyrosine; Tyrphostins

1999
Epidermal and hepatocyte growth factors stimulate chemotaxis in an intestinal epithelial cell line.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Animals; Cell Division; Cell Line, Transformed; Chemotaxis; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Extracellular Matrix; Fibroblast Growth Factor 1; Fibroblast Growth Factor 10; Fibroblast Growth Factor 2; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Flavonoids; Genistein; Growth Substances; Hepatocyte Growth Factor; Insulin-Like Growth Factor I; Intestines; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Quinazolines; Transforming Growth Factor beta; Type C Phospholipases; Tyrphostins

1999
A specific inhibitor of janus kinase-3 increases survival in a transgenic mouse model of amyotrophic lateral sclerosis.
    Biochemical and biophysical research communications, 2000, Jan-07, Volume: 267, Issue:1

    Topics: Animals; Antioxidants; Disease Models, Animal; Enzyme Inhibitors; Genetic Variation; Genistein; Heterozygote; Humans; Janus Kinase 3; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Motor Neuron Disease; Neuroprotective Agents; Paralysis; Protein-Tyrosine Kinases; Quinazolines; Superoxide Dismutase

2000
A role for bovine herpesvirus 1 (BHV-1) glycoprotein E (gE) tyrosine phosphorylation in replication of BHV-1 wild-type virus but not BHV-1 gE deletion mutant virus.
    Virology, 2000, Mar-01, Volume: 268, Issue:1

    Topics: Animals; Capsid; Cell Line; Dogs; Gene Deletion; Genistein; Herpesvirus 1, Bovine; Mutation; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Quinazolines; Tyrphostins; Viral Envelope Proteins; Viral Proteins; Virus Replication

2000
Receptor tyrosine kinase inhibition suppresses growth of pediatric renal tumor cells in vitro.
    Journal of pediatric surgery, 2000, Volume: 35, Issue:6

    Topics: Adult; Cell Division; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Genistein; Humans; Infant; Kidney Neoplasms; Male; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Quinazolines; Receptor Protein-Tyrosine Kinases; Rhabdoid Tumor; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrphostins; Wilms Tumor

2000
c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
    The Journal of biological chemistry, 2001, May-11, Volume: 276, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aorta; Benzoquinones; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Genistein; GRB2 Adaptor Protein; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Pyrimidines; Quinazolines; Quinones; Rifabutin; Swine; Transcriptional Activation; Tyrphostins

2001
Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse.
    Nature, 2001, May-17, Volume: 411, Issue:6835

    Topics: Animals; Antigens, CD; Calcium-Binding Proteins; Cell Adhesion; Cells, Cultured; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Genistein; Glutamic Acid; Hippocampus; Integrin beta3; Integrins; Intercellular Signaling Peptides and Proteins; Isoflavones; Membrane Glycoproteins; Models, Neurological; Nerve Tissue Proteins; Neurons; Oligopeptides; Peptides; Platelet Membrane Glycoproteins; Presynaptic Terminals; Protein Subunits; Quinazolines; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses; Synaptotagmin I; Synaptotagmins; Tyrphostins

2001
Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: Animals; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Genistein; Hydrogen Peroxide; Imidazoles; Immunoblotting; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Plant Proteins; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Rats; Rats, Wistar; Sarcolemma; Signal Transduction; Sodium-Hydrogen Exchangers; src-Family Kinases; Tyrphostins

2002
Direct inhibition of the cloned Kv1.5 channel by AG-1478, a tyrosine kinase inhibitor.
    American journal of physiology. Cell physiology, 2002, Volume: 282, Issue:6

    Topics: Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Genistein; Kv1.5 Potassium Channel; Membrane Potentials; Patch-Clamp Techniques; Phenols; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein-Tyrosine Kinases; Quinazolines; Rats; Time Factors; Transfection; Tyrphostins

2002
Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis.
    Biochemical and biophysical research communications, 2002, Jul-12, Volume: 295, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line; ErbB Receptors; Genistein; Membrane Glycoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinazolines; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2002
Antagonistic regulation of swelling-activated Cl- current in rabbit ventricle by Src and EGFR protein tyrosine kinases.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6

    Topics: Animals; Cadmium; Chloride Channels; Enzyme Inhibitors; ErbB Receptors; Genistein; Heart Ventricles; Membrane Potentials; Pyrimidines; Quinazolines; Rabbits; src-Family Kinases; Tamoxifen; Ventricular Function

2005
[Effect of tyrosine kinase inhibitors on airway remodeling in bronchial asthma].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2005, Volume: 36, Issue:1

    Topics: Animals; Asthma; Cells, Cultured; ErbB Receptors; Genistein; Male; Protein-Tyrosine Kinases; Quinazolines; Random Allocation; Rats; Rats, Sprague-Dawley; Trachea; Tyrphostins

2005
The role of tyrosine kinase-mediated pathways in diabetes-induced alterations in responsiveness of rat carotid artery.
    Autonomic & autacoid pharmacology, 2005, Volume: 25, Issue:2

    Topics: Animals; Benzothiazoles; Body Weight; Carotid Arteries; Diabetes Mellitus, Experimental; Enzyme Inhibitors; ErbB Receptors; Female; Genes, erbB-1; Genes, erbB-2; Genistein; In Vitro Techniques; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2005
Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.
    British journal of pharmacology, 2005, Volume: 145, Issue:6

    Topics: Angiotensin II; Animals; Carbachol; Cell Line; Diabetes Mellitus, Experimental; Endothelin-1; ErbB Receptors; Female; Genistein; Histamine; Humans; In Vitro Techniques; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Streptozocin; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2005
Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor.
    American journal of respiratory cell and molecular biology, 2005, Volume: 33, Issue:4

    Topics: Animals; Arginase; Cattle; Cells, Cultured; Cytokines; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; ErbB Receptors; Genistein; Growth Inhibitors; Humans; Isoenzymes; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Pulmonary Artery; Quinazolines; Tumor Necrosis Factor-alpha; Tyrphostins; Urea

2005
Inhibitors of tyrosine kinase inhibit the production of urokinase plasminogen activator in human prostatic cancer cells.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2005, Volume: 113, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Genistein; Humans; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Tumor Cells, Cultured; Tyrphostins; Urokinase-Type Plasminogen Activator

2005
Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line.
    BMC cancer, 2006, Jan-24, Volume: 6

    Topics: Antimitotic Agents; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA; DNA Primers; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genistein; Histones; Humans; Isoflavones; Kinesins; Male; Models, Statistical; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Spindle Apparatus; Tetrazolium Salts; Thiazoles

2006
The invasive behaviour of prostatic cancer cells is suppressed by inhibitors of tyrosine kinase.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2006, Volume: 114, Issue:1

    Topics: Basement Membrane; Biological Assay; Carcinoma; Cell Movement; Collagen; Drug Combinations; Genistein; Humans; Laminin; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plasminogen; Plasminogen Activators; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proteoglycans; Quinazolines; Tyrphostins

2006
Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells.
    Toxicology letters, 2006, Aug-20, Volume: 165, Issue:2

    Topics: Adult; Benzo(a)pyrene; Calcium; Calcium Signaling; Carcinogens, Environmental; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Enzyme Inhibitors; Epidermal Growth Factor; Female; Genistein; Humans; Myometrium; Oxytocin; Pregnancy; Protein-Tyrosine Kinases; Quinazolines; Tetraethylammonium; Tyrphostins

2006
Tyrosine kinase inhibitors alter adhesivity of prostatic cancer cells to extracellular matrix components.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2006, Volume: 114, Issue:3

    Topics: Cell Adhesion; Cell Line, Tumor; Cell Survival; Extracellular Matrix; Genistein; Humans; Integrins; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Quinazolines; Tyrphostins

2006
Urokinase plasminogen activator receptor (uPAR) expression is reduced by tyrosine kinase inhibitors.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2006, Volume: 114, Issue:4

    Topics: Adenocarcinoma; Cell Line, Tumor; Gene Expression; Genistein; Humans; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tyrphostins

2006
Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:2

    Topics: Absorption; Animals; Bicarbonates; Carbon Dioxide; Dimethyl Sulfoxide; Enzyme Inhibitors; Female; Genistein; Imidazoles; Kidney Tubules, Proximal; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Rabbits; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction

2006
Transcription levels of invasion-related genes in prostate cancer cells are modified by inhibitors of tyrosine kinase.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2006, Volume: 114, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genistein; Humans; Male; Metalloproteases; Prostatic Neoplasms; Protein Array Analysis; Protein-Tyrosine Kinases; Quinazolines; RNA, Messenger; Transcription, Genetic; Tyrphostins; Urokinase-Type Plasminogen Activator

2006
Inhibition of leiomyoma cell proliferation in vitro by genistein and the protein tyrosine kinase inhibitor TKS050.
    Fertility and sterility, 2007, Volume: 87, Issue:1

    Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Female; Genistein; Humans; Leiomyoma; Protein-Tyrosine Kinases; Quinazolines; Tumor Cells, Cultured; Uterine Neoplasms

2007
Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kappaB.
    Cancer research, 2006, Nov-01, Volume: 66, Issue:21

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Gemcitabine; Genistein; Humans; NF-kappa B; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction

2006
Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages.
    Experimental & molecular medicine, 2007, Aug-31, Volume: 39, Issue:4

    Topics: Animals; Benzoflavones; Cell Differentiation; Cell Line, Tumor; Enzyme Activation; ErbB Receptors; Genistein; Hazardous Substances; Humans; Macrophages; MAP Kinase Signaling System; Mice; Phosphorylation; Polychlorinated Dibenzodioxins; Pyrimidines; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; src-Family Kinases; Tumor Necrosis Factor-alpha

2007
Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 456, Issue:3

    Topics: Action Potentials; Animals; Cell Size; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; ErbB Receptors; Genistein; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Kinetics; Myocytes, Cardiac; Osmotic Pressure; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Signal Transduction; src-Family Kinases; Tyrphostins; Vanadates

2008
Genistein decreases androgen biosynthesis in rat Leydig cells by interference with luteinizing hormone-dependent signaling.
    Toxicology letters, 2009, Feb-10, Volume: 184, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic CMP; Dose-Response Relationship, Drug; Down-Regulation; Endocrine Disruptors; Enzyme Activators; Epidermal Growth Factor; ErbB Receptors; Genistein; Leydig Cells; Luteinizing Hormone; Male; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Long-Evans; Receptors, LH; Signal Transduction; Testosterone; Tyrphostins

2009
Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines.
    Cancer, 2009, May-15, Volume: 115, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Genistein; Humans; Lung Neoplasms; NF-kappa B; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines

2009
Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells.
    Free radical research, 2010, Volume: 44, Issue:7

    Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Antioxidants; Female; G2 Phase; Genistein; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Metaphase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidation-Reduction; Plant Extracts; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Reactive Oxygen Species; Signal Transduction

2010
Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin.
    Archives of virology, 2012, Volume: 157, Issue:1

    Topics: Antiviral Agents; Cell Line; Ebolavirus; Genistein; Hemorrhagic Fever, Ebola; Humans; Lassa Fever; Lassa virus; Protein Kinase Inhibitors; Quinazolines; Tyrphostins

2012
Synergistic inhibitory effects by the combination of gefitinib and genistein on NSCLC with acquired drug-resistance in vitro and in vivo.
    Molecular biology reports, 2012, Volume: 39, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Gefitinib; Genistein; Humans; Inhibitory Concentration 50; Lung Neoplasms; Mice; Mutation; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Xenograft Model Antitumor Assays

2012