Page last updated: 2024-08-21

quinazolines and evp 4593

quinazolines has been researched along with evp 4593 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Ahlijanian, M; Bezprozvanny, I; Chen, X; Chesworth, R; Diggins, L; Glushankova, L; Hrdlicka, L; Kaznacheyeva, E; Koenig, G; Mahoney, M; Mozhayeva, GN; Shapiro, G; Shih, HP; Singh, C; Vigont, V; Wu, J; Wu, Q; Zimina, O1
de Barros, NB; de Figueiredo Nicolete, LD; Ferreira, Ados S; Macedo, SR; Nicolete, R1
Bhatt, ML; Dubey, P; Kumar, V; Mati Goel, M; Misra, S; Singh Baghel, K; Singh Negi, MP; Tewari, BN; Tripathi, C1
Hsu, FT; Pan, PJ; Tsai, JJ1
Chung, JG; Hsu, FT; Lin, SS; Wu, JY1
Brands, RC; El-Mesery, M; Hartmann, S; Kübler, AC; Müller-Richter, UDA; Scheurer, MJJ; Seher, A1
Bezprozvanny, I; Chernyuk, D; Kabirova, M; Popugaeva, E; Zernov, N1
Gu, ZL; Huang, J; Zhen, LL1
Deng, Y; Gao, H; Xu, YQ; Zhu, SB1
Al-Gayyar, MMH; Alattar, A; Alshaman, R; Hamdan, AM1
Cavina, B; De Luise, M; Fornasa, A; Gasparre, G; Ghelli, A; Iommarini, L; Iorio, M; Kurelac, I; Lama, E; Miglietta, S; Musiani, F; Nasiri, HR; Porcelli, AM; Sollazzo, M; Traversa, D1
Grekhnev, DA; Kaznacheyeva, EV; Kruchinina, AA; Vigont, VA1

Reviews

1 review(s) available for quinazolines and evp 4593

ArticleYear
The Mystery of EVP4593: Perspectives of the Quinazoline-Derived Compound in the Treatment of Huntington's Disease and Other Human Pathologies.
    International journal of molecular sciences, 2022, Dec-11, Volume: 23, Issue:24

    Topics: Humans; Huntingtin Protein; Huntington Disease; Neurons; Phenyl Ethers; Quinazolines

2022

Other Studies

11 other study(ies) available for quinazolines and evp 4593

ArticleYear
Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment.
    Chemistry & biology, 2011, Jun-24, Volume: 18, Issue:6

    Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Disease Models, Animal; Drosophila; Fura-2; Glutamic Acid; Huntingtin Protein; Huntington Disease; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; NF-kappa B; Nuclear Proteins; Phenyl Ethers; Quinazolines; RNA Interference; RNA, Small Interfering; TRPC Cation Channels

2011
The pentavalent antimonial therapy against experimental Leishmania amazonensis infection is more effective under the inhibition of the NF-κB pathway.
    International immunopharmacology, 2015, Volume: 28, Issue:1

    Topics: Animals; Antiprotozoal Agents; Drug Therapy, Combination; Interleukin-10; Interleukin-12; Interleukin-1beta; Leishmania mexicana; Leishmaniasis, Cutaneous; Macrophages, Peritoneal; Meglumine; Meglumine Antimoniate; Mice, Inbred BALB C; NF-kappa B; Organometallic Compounds; Phenyl Ethers; Quinazolines; Signal Transduction

2015
A study on local expression of NF-κB, CCL2 and their involvement in intratumoral macrophage infiltration in breast cancer.
    Cellular and molecular biology (Noisy-le-Grand, France), 2016, Feb-29, Volume: 62, Issue:2

    Topics: Adult; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Breast Neoplasms; Cell Line, Tumor; Chemokine CCL2; Female; Gene Expression Regulation; Humans; Immunohistochemistry; Macrophages; Middle Aged; NF-kappa B; Odds Ratio; Phenyl Ethers; Quinazolines; Real-Time Polymerase Chain Reaction; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger

2016
Regorafenib induces extrinsic and intrinsic apoptosis through inhibition of ERK/NF-κB activation in hepatocellular carcinoma cells.
    Oncology reports, 2017, Volume: 37, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; NF-kappa B; Phenyl Ethers; Phenylurea Compounds; Phosphorylation; Pyridines; Quinazolines; X-Linked Inhibitor of Apoptosis Protein

2017
Fluoxetine Inhibits DNA Repair and NF-ĸB-modulated Metastatic Potential in Non-small Cell Lung Cancer.
    Anticancer research, 2018, Volume: 38, Issue:9

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; DNA Repair; Fluoxetine; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Metastasis; NF-kappa B; Phenyl Ethers; Quinazolines; Signal Transduction

2018
The Selection of NFκB Inhibitors to Block Inflammation and Induce Sensitisation to FasL-Induced Apoptosis in HNSCC Cell Lines Is Critical for Their Use as a Prospective Cancer Therapy.
    International journal of molecular sciences, 2019, Mar-15, Volume: 20, Issue:6

    Topics: Amides; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Fas Ligand Protein; Head and Neck Neoplasms; Humans; Hydrocortisone; Interleukin-8; NF-kappa B; Phenyl Ethers; Pyrimidines; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Tumor Necrosis Factor-alpha

2019
Antagonist of neuronal store-operated calcium entry exerts beneficial effects in neurons expressing PSEN1ΔE9 mutant linked to familial Alzheimer disease.
    Neuroscience, 2019, 07-01, Volume: 410

    Topics: Alzheimer Disease; Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Cells, Cultured; Gene Expression; Hippocampus; Membrane Proteins; Mice; Mice, Transgenic; Mutation; Neurons; Phenyl Ethers; Presenilin-1; Quinazolines; Treatment Outcome

2019
Knockdown of otubain 2 inhibits liver cancer cell growth by suppressing NF-κB signaling.
    The Kaohsiung journal of medical sciences, 2020, Volume: 36, Issue:6

    Topics: Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Hepatoblastoma; Humans; Liver Neoplasms; Luciferases; Phenyl Ethers; Phenylenediamines; Phosphorylation; Quinazolines; RNA, Small Interfering; Signal Transduction; Survival Analysis; Thiolester Hydrolases; Transcription Factor RelA

2020
NF-κB inhibitor QNZ protects human chondrocyte degeneration by promoting glucose uptake through Glut4 activation.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:9

    Topics: Aged; Cells, Cultured; Chondrocytes; Female; Glucose; Glucose Transporter Type 4; Humans; Male; Middle Aged; NF-kappa B; Phenyl Ethers; Quinazolines

2020
QNZ alleviated hepatocellular carcinoma by targeting inflammatory pathways in a rat model.
    Cytokine, 2021, Volume: 148

    Topics: alpha-Fetoproteins; Animals; beta Catenin; Carcinoma, Hepatocellular; Disease Models, Animal; Glycogen Synthase Kinase 3; Hepatocytes; Inflammation; Liver; Liver Neoplasms; MAP Kinase Kinase Kinase 5; NF-kappa B; Organ Specificity; Phenyl Ethers; Quinazolines; Rats; Rats, Sprague-Dawley; Survival Analysis; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha

2021
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors.
    Open biology, 2022, Volume: 12, Issue:11

    Topics: Electron Transport Complex I; Humans; Metformin; Molecular Docking Simulation; NADH Dehydrogenase; Neoplasms; Quinazolines

2022