Page last updated: 2024-08-21

quinazolines and enzastaurin

quinazolines has been researched along with enzastaurin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stummer, W1
Bianco, R; Caputo, R; Ciardiello, F; Damiano, V; Daniele, G; Gelardi, T; Lahn, M; Pepe, S; Tortora, G1
Chhatwani, L; Colevas, AD; Decker, R; Fisher, GA; Krupitskaya, Y; Latz, JE; Padda, SK; San Pedro-Salcedo, M; Wakelee, HA1
Bernstein, ED; ClĂ©ment-DuchĂȘne, C; Dudek, AZ; Jahan, T; Krupitskaya, Y; Latz, JE; Natale, RB; Osarogiagbon, R; Sanborn, RE; Shi, P; Wakelee, HA1
Cartron, PF; Cheray, M; Nadaradjane, A; Pacaud, R; Vallette, FM1

Trials

2 trial(s) available for quinazolines and enzastaurin

ArticleYear
A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib in patients with advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Indoles; Male; Middle Aged; Neoplasms; Quinazolines

2012
A phase II study of enzastaurin in combination with erlotinib in patients with previously treated advanced non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2012, Volume: 78, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Erlotinib Hydrochloride; Female; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Quinazolines; Risk Factors; Treatment Outcome

2012

Other Studies

3 other study(ies) available for quinazolines and enzastaurin

ArticleYear
Perspectives in central nervous system malignancies.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Central Nervous System Neoplasms; Combined Modality Therapy; Drug Therapy, Combination; ErbB Receptors; Gefitinib; Glioma; Humans; Indoles; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Quinazolines; Randomized Controlled Trials as Topic; Sirolimus; TOR Serine-Threonine Kinases

2006
Enzastaurin inhibits tumours sensitive and resistant to anti-EGFR drugs.
    British journal of cancer, 2008, Aug-05, Volume: 99, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Culture Media, Conditioned; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Gefitinib; Humans; Indoles; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Quinazolines; Vascular Endothelial Growth Factor A

2008
Histone H3 phosphorylation in GBM: a new rational to guide the use of kinase inhibitors in anti-GBM therapy.
    Theranostics, 2015, Volume: 5, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Dacarbazine; Female; Glioblastoma; Histones; Humans; Indoles; Male; Middle Aged; Organophosphates; Phosphorylation; Prognosis; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrazoles; Pyrimidines; Quinazolines; Temozolomide

2015