quinazolines has been researched along with endothelin-1 in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 13 (72.22) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahn, K; Cheng, XM; Doherty, AM; Emoto, N; Haleen, SJ; Herman, SB; Hupe, D; Kaw, S; Lee, C; Nikam, S; Pan, SM; Schroeder, RL; Sisneros, AM; Yanagisawa, M | 1 |
| Eguchi, S; Hirata, Y; Iwasaki, H; Marumo, F | 1 |
| Inoue, M; Iwamoto, A; Kanda, T; Kobayashi, I; Nagai, R; Sakamaki, T; Sato, K; Sumino, H; Takahashi, T | 1 |
| Ahn, K; Fahnoe, DC; Herman, SB; Johnson, GD | 1 |
| Bagnato, A; Catt, KJ; Tecce, R; Vacca, F | 1 |
| Chatziantoniou, C; Coffman, T; Dussaule, JC; Flamant, M; Henrion, D; Placier, S; Tharaux, PL | 1 |
| Chansel, D; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Placier, S; Tharaux, PL | 1 |
| Araie, M; Asai, Y; Hara, H; Ichikawa, M; Ishii, K; Okada, Y | 1 |
| Goto, K | 1 |
| Slomiany, A; Slomiany, BL | 2 |
| Goto, W; Ikeda, T; Oku, H; Okuno, T; Sugiyama, T | 1 |
| Bagnato, A; Di Castro, V; Elia, G; Natali, PG; Rosanò, L; Spinella, F | 1 |
| Akhtar, S; Benboubetra, M; Benter, IF; Griffiths, SM; Yousif, MH | 1 |
| Casas-González, P; García-Sáinz, JA | 1 |
| Chao, HH; Chen, YL; Cheng, TH; Chiu, WT; Hong, HJ; Lin, JW; Liu, JC; Shyu, KG; Wu, CH | 1 |
| Guo, RL; He, KW; Hu, YY | 1 |
| Corvetta, D; Di Pierro, AM; Eakins, E; Feistritzer, C; Gambato, R; Gastl, G; Gherlinzoni, F; Gottardi, M; Krampera, M; Langes, M; Marcheselli, L; Mazzoleni, G; Mega, A; Murphy, C; Pacquola, E; Perbellini, O; Piccin, A; Piva, E; Plebani, M; Pusceddu, I; Steurer, M; Tauber, M; Van Schilfgaarde, M; Veneri, D | 1 |
1 review(s) available for quinazolines and endothelin-1
| Article | Year |
|---|---|
[Prospects for endothelin-related drugs].
Topics: Animals; Aspartic Acid Endopeptidases; Bosentan; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Hemodynamics; Humans; Metalloendopeptidases; Organophosphonates; Peptides, Cyclic; Quinazolines; Receptors, Endothelin; Sulfonamides; Sulfonylurea Compounds; Tetracyclines; Tetrazoles | 2004 |
17 other study(ies) available for quinazolines and endothelin-1
| Article | Year |
|---|---|
Novel selective quinazoline inhibitors of endothelin converting enzyme-1.
Topics: Animals; Aspartic Acid Endopeptidases; CHO Cells; Cricetinae; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Metalloendopeptidases; Perfusion; Pressure; Protein Precursors; Quinazolines; Rats; Rats, Sprague-Dawley; Transfection | 1998 |
Endothelin-1 stimulates DNA synthesis of vascular smooth-muscle cells through transactivation of epidermal growth factor receptor.
Topics: Animals; Biotransformation; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Male; Muscle, Smooth, Vascular; Nitriles; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-fos; Quinazolines; Rats; Rats, Sprague-Dawley; Tyrphostins | 1998 |
Type V phosphodiesterase inhibition modulates endogenous immunoreactivities of endothelin-1 and endothelial nitric oxide synthase in pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Oral; Animals; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Endothelin-1; Hypertension, Pulmonary; Immunohistochemistry; Male; Monocrotaline; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Pulmonary Artery; Quinazolines; Rats; Rats, Wistar; Receptors, Endothelin | 1998 |
Disulfide bonds in big ET-1 are essential for the specific cleavage at the Trp(21)-Val(22) bond by soluble endothelin converting enzyme-1 from baculovirus/insect cells.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Baculoviridae; Bradykinin; Chromatography, High Pressure Liquid; Disulfides; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Glycopeptides; Glycosylation; Humans; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Peptide Fragments; Protein Precursors; Quinazolines; Recombinant Proteins; Spectrometry, Fluorescence; Spodoptera | 2000 |
Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Cell Division; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Ovarian Neoplasms; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proteins; Quinazolines; Receptor, Endothelin A; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice.
Topics: Animals; Aorta; Blood Pressure; Collagen Type I; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Fibrosis; Flavonoids; In Vitro Techniques; Luciferases; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Quinazolines; Tyrphostins; Vasoconstriction | 2003 |
Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition.
Topics: Animals; Capillaries; Collagen; Collagen Type I; Creatinine; Endothelin-1; ErbB Receptors; Fibrosis; Gefitinib; Gene Expression Regulation; Genes, Reporter; Glomerulosclerosis, Focal Segmental; Hypertension; Ischemia; Kidney; Kidney Cortex; Kidney Diseases; Kidney Glomerulus; Male; MAP Kinase Signaling System; Mice; Mice, Transgenic; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proteinuria; Quinazolines; Rats; Rats, Sprague-Dawley | 2004 |
Effects of topically instilled bunazosin, an alpha1-adrenoceptor antagonist, on constrictions induced by phenylephrine and ET-1 in rabbit retinal arteries.
Topics: Administration, Topical; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Dose-Response Relationship, Drug; Drug Combinations; Endothelin-1; Ganglionectomy; Injections; Male; Phenylephrine; Quinazolines; Rabbits; Receptors, Endothelin; Retinal Artery; Superior Cervical Ganglion; Vasoconstriction; Vasoconstrictor Agents; Vitreous Body | 2004 |
Porphyromonas gingivalis lipopolysaccharide-induced up-regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; ErbB Receptors; Lipopolysaccharides; Mucins; Oligopeptides; Porphyromonas gingivalis; Pyrimidines; Quinazolines; Rats; Saliva; Salivary Glands; src-Family Kinases; Time Factors; Transcriptional Activation; Trypan Blue; Up-Regulation | 2004 |
Amelioration of endothelin-1-induced optic nerve head ischemia by topical bunazosin.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Endothelin-1; Evoked Potentials, Visual; Injections; Intraocular Pressure; Ischemia; Optic Disk; Quinazolines; Rabbits; Regional Blood Flow; Retina; Vitreous Body | 2005 |
Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Induction; ErbB Receptors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor, Endothelin A; Signal Transduction; Transcriptional Activation; Tyrphostins | 2004 |
Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.
Topics: Angiotensin II; Animals; Carbachol; Cell Line; Diabetes Mellitus, Experimental; Endothelin-1; ErbB Receptors; Female; Genistein; Histamine; Humans; In Vitro Techniques; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Streptozocin; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Up-regulation in endothelin-1 by Helicobacter pylori lipopolysaccharide interferes with gastric mucin synthesis via epidermal growth factor receptor transactivation.
Topics: Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; ErbB Receptors; Gastric Mucins; Gastric Mucosa; Helicobacter pylori; In Vitro Techniques; Lipopolysaccharides; Metalloendopeptidases; Quinazolines; Rats; Rats, Sprague-Dawley; Transcriptional Activation; Up-Regulation | 2005 |
Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation.
Topics: Adrenergic alpha-Agonists; Androstadienes; Animals; Antibodies; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Endothelin-1; Epidermal Growth Factor; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Norepinephrine; Phenylalanine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Thiophenes; Tyrphostins; Wortmannin | 2006 |
Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Blotting, Northern; Blotting, Western; Butadienes; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Endothelin-1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Leptin; Male; Metalloendopeptidases; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Signal Transduction; Transcriptional Activation; Tyrosine; Tyrphostins | 2007 |
Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Benzylisoquinolines; Cells, Cultured; Down-Regulation; Drugs, Chinese Herbal; E-Selectin; Endothelin-1; Endothelium, Vascular; Evodia; Humans; Interleukin-1alpha; Lipopolysaccharides; Morphinans; Proline; Pyrazines; Quinazolines; Quinolizines; Swine; Thromboxane B2 | 2012 |
Observational retrospective study of vascular modulator changes during treatment in essential thrombocythemia.
Topics: Adrenomedullin; Aged; Aspirin; Blood Platelets; Case-Control Studies; Cell-Derived Microparticles; Endothelin-1; Endothelium, Vascular; Female; Humans; Hydroxyurea; Male; Middle Aged; Nitric Oxide; Quinazolines; Retrospective Studies; Thrombocythemia, Essential | 2017 |