quinazolines has been researched along with elacridar in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V | 1 |
| Fukumura, T; Hatori, A; Irie, T; Kanno, I; Kawamura, K; Konno, F; Kumata, K; Suzuki, K; Yamasaki, T; Yui, J; Zhang, MR | 1 |
| Agarwal, S; Elmquist, WF; Gallardo, JL; Ohlfest, JR; Sane, R | 1 |
| Balani, SK; Gan, L; Lee, FW; Liao, M; Liu, N; Milton, MN; Prakash, S; Wu, JT; Xia, CQ; Yang, JJ; Yu, S | 1 |
| Elmquist, WF; Mittapalli, RK; Sane, R | 1 |
| DeGroot, J; Jansen, HT; Kivits, S; Läppchen, T; Sio, CF; Steinbach, OC; van de Steeg, E; van der Hoorn, JW; van Driel, A; Vlaming, ML | 1 |
| Kanamitsu, K; Kusuhara, H; Schuetz, JD; Sugiyama, Y; Takeuchi, K | 1 |
| Crish, JF; Elmquist, WF; Gampa, G; Hinojosa, AQ; Kenchappa, RS; Kim, M; Luu, A; Mohammad, AS; Parrish, KE; Rosenfeld, SS; Sarkaria, JN; West, R | 1 |
8 other study(ies) available for quinazolines and elacridar
| Article | Year |
|---|---|
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [(11)C]gefitinib.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain; Carbon Radioisotopes; Gefitinib; Male; Mice; Neoplasm Proteins; Positron-Emission Tomography; Quinazolines; Radioactivity; Tetrahydroisoquinolines | 2009 |
Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active efflux.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Blood-Brain Barrier; Brain; Cell Line; Cell Membrane Permeability; Dogs; Gefitinib; Male; Mice; Mice, Knockout; Quinazolines; Tetrahydroisoquinolines; Tissue Distribution; Transfection | 2010 |
P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
Topics: Acridines; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Brain; Caco-2 Cells; Humans; Injections, Intravenous; Intestinal Mucosa; Male; Mice; Mice, Knockout; Neoplasm Proteins; Piperazines; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines | 2010 |
Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Brain; Cell Line; Dasatinib; Dogs; Drug Delivery Systems; Emulsions; Erlotinib Hydrochloride; Humans; Mice; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Solubility; Tetrahydroisoquinolines; Thiazoles | 2013 |
PET-CT imaging with [(18)F]-gefitinib to measure Abcb1a/1b (P-gp) and Abcg2 (Bcrp1) mediated drug-drug interactions at the murine blood-brain barrier.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Cell Line, Tumor; Drug Interactions; Fluorine Radioisotopes; Gefitinib; Humans; Male; Mice; Positron-Emission Tomography; Quinazolines; Tetrahydroisoquinolines; Tissue Distribution; Tomography, X-Ray Computed | 2015 |
Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-Brain Barrier.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acridines; Adenosine Triphosphate; Animals; Biological Transport; Blood-Brain Barrier; Brain; Central Nervous System; Cyclic GMP; Humans; Kinetics; Male; Methotrexate; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Ochratoxins; Pravastatin; Quinazolines; Quinolines; Tetrahydroisoquinolines; Thiophenes; Uric Acid | 2017 |
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzamides; Blood-Brain Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Glioblastoma; Humans; Kinesins; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Quinazolines; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays | 2020 |