Compounds > quinazolines
Page last updated: 2024-08-21

quinazolines and efavirenz

quinazolines has been researched along with efavirenz in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, PS; Bacheler, LT; Corbett, JW; Cordova, BC; Diamond, S; Erickson-Viitanen, SK; Garber, S; Gearhart, LA; Jeffrey, S; Klabe, RM; Ko, SS; Logue, K; Magnus, NA; Rodgers, JD; Trainor, GL1
Bacheler, LT; Chidester, DR; Cocuzza, AJ; Cordova, BC; Diamond, S; Erickson-Viitanen, SK; Jeffrey, S; Klabe, RM; Ko, SS; Rodgers, JD; Weigelt, CA1
Caballero, J; Castro, EA; Duchowicz, PR; Fernández, FM; Fernández, M1
Beumer, JH; Christner, SM; Gramignoli, R; Parise, RA; Pillai, VC; Rudek, MA; Strom, SC; Venkataramanan, R1
Anders, NM; Beumer, JH; Deeken, JF; Rudek, MA; Rusnak, M; Wanjiku, T1

Other Studies

5 other study(ies) available for quinazolines and efavirenz

ArticleYear
Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 2000, May-18, Volume: 43, Issue:10

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Blood Proteins; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Structure; Mutation; Oxazines; Protein Binding; Quinazolines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication

2000
4,1-Benzoxazepinone analogues of efavirenz (Sustiva) as HIV-1 reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 2001, Jun-04, Volume: 11, Issue:11

    Topics: Alkynes; Animals; Benzoxazines; Cyclopropanes; HIV Reverse Transcriptase; Humans; Macaca mulatta; Oxazines; Protein Binding; Quinazolines; Quinazolinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2001
QSAR for non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry, 2006, Sep-01, Volume: 14, Issue:17

    Topics: Alkynes; Benzoxazines; Combinatorial Chemistry Techniques; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Mutation; Oxazines; Quantitative Structure-Activity Relationship; Quinazolines; Quinazolinones; Reverse Transcriptase Inhibitors

2006
Ritonavir and efavirenz significantly alter the metabolism of erlotinib--an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:10

    Topics: 14-alpha Demethylase Inhibitors; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; Erlotinib Hydrochloride; Female; Half-Life; Hepatocytes; HIV Infections; HIV Protease Inhibitors; Humans; Ketoconazole; Male; Middle Aged; Neoplasms; Nucleic Acid Synthesis Inhibitors; Quinazolines; Rifampin; Ritonavir

2013
Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib.
    Cancer chemotherapy and pharmacology, 2015, Volume: 76, Issue:4

    Topics: Administration, Oral; Alkynes; Animals; Anti-Retroviral Agents; Antineoplastic Agents; Benzoxazines; Biological Availability; Biotransformation; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Drug Evaluation, Preclinical; Drug Interactions; Erlotinib Hydrochloride; Half-Life; Ketoconazole; Male; Metabolic Clearance Rate; Mice, Inbred Strains; Protein Kinase Inhibitors; Quinazolines; Ritonavir

2015