Compounds > quinazolines
Page last updated: 2024-08-21

quinazolines and edatrexate

quinazolines has been researched along with edatrexate in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (80.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fleming, GF; Schilsky, RL1
Bertino, JR; Chang, YM; Li, WW; Lin, JT; Schweitzer, B1
Jansen, G; Peters, GJ; Pinedo, HM; Rijnboutt, S; Schornagel, JH; Westerhof, GR1
Jansen, G; Pinedo, HM; Rijnboutt, S; Schornagel, JH; Westerhof, GR1
Jansen, G; Jolivet, J; Kathmann, I; Molthoff, C; Pinard, MF; Ratnam, M; Schornagel, JH; Westerhof, R1
Allegra, CJ; Takimoto, CH1
Armand, JP1
Takimoto, CH1
Strømhaug, A; Warren, DJ1
Kris, MG; Miller, VA; Scher, HI; Sirotnak, FM; Zakowski, MF1

Reviews

4 review(s) available for quinazolines and edatrexate

ArticleYear
Antifolates: the next generation.
    Seminars in oncology, 1992, Volume: 19, Issue:6

    Topics: Aminopterin; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Clinical Trials as Topic; Drug Evaluation; Folic Acid Antagonists; Forecasting; Humans; Neoplasms; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate

1992
New antifolates in clinical development.
    Oncology (Williston Park, N.Y.), 1995, Volume: 9, Issue:7

    Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents; Drugs, Investigational; Folic Acid Antagonists; Humans; Neoplasms; Pyrimidines; Quinazolines; Thiophenes; Trimetrexate

1995
New anticancer drugs in Europe.
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24 Suppl 1

    Topics: Aminopterin; Anthraquinones; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Aziridines; Bridged-Ring Compounds; Bryostatins; Camptothecin; Dacarbazine; Deoxycytidine; Distamycins; Doxorubicin; Europe; Gemcitabine; Humans; Indolequinones; Indoles; Irinotecan; Lactones; Macrolides; Nitrogen Mustard Compounds; Nitrosourea Compounds; Pyrazoles; Quinazolines; Taxoids; Temozolomide; Thiophenes; Vinca Alkaloids

1997
Antifolates in clinical development.
    Seminars in oncology, 1997, Volume: 24, Issue:5 Suppl 18

    Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Clinical Trials as Topic; Drug Design; Enzyme Inhibitors; Folic Acid Antagonists; Glutamates; Guanine; Humans; Indoles; Isoindoles; Pemetrexed; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidylate Synthase

1997

Other Studies

6 other study(ies) available for quinazolines and edatrexate

ArticleYear
Prediction of antifolate efficacy in a rat sarcoma model.
    International journal of cancer, 1991, Sep-09, Volume: 49, Issue:2

    Topics: Aminopterin; Animals; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Male; Methotrexate; Methylcholanthrene; Quinazolines; Rats; Sarcoma, Experimental; Thymidylate Synthase; Trimetrexate

1991
Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.
    Cancer research, 1995, Sep-01, Volume: 55, Issue:17

    Topics: Aminopterin; Animals; Carrier Proteins; Cell Division; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Glutamates; Haplorhini; Humans; Kidney; Leucovorin; Methotrexate; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Quinazolines; Receptors, Cell Surface; Tetrahydrofolates; Thiophenes; Tumor Cells, Cultured

1995
Identification of a reduced folate/methotrexate carrier in human KB-cells expressing high levels of membrane associated folate binding protein.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: Aminopterin; Biological Transport; Carrier Proteins; Cell Division; Cell Membrane; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; KB Cells; Kinetics; Leucovorin; Methotrexate; Quinazolines; Receptors, Cell Surface; Structure-Activity Relationship

1993
Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:3

    Topics: Aminopterin; Antimetabolites, Antineoplastic; Binding Sites; Breast Neoplasms; Carrier Proteins; Cell Membrane; DNA, Complementary; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Polymerase Chain Reaction; Quinazolines; Receptors, Cell Surface; RNA, Messenger; Spectrometry, Fluorescence; Structure-Activity Relationship; Tetrahydrofolates; Thiophenes; Tumor Cells, Cultured

1996
A comparison of the effects of nine folate analogs on early and late murine hematopoietic progenitor cells in vitro.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:6

    Topics: Aminopterin; Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Hematopoietic Stem Cells; Methotrexate; Mice; Mice, Inbred BALB C; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate

2000
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Aminopterin; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carboplatin; Cell Division; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; ErbB Receptors; Female; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Male; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Prostatic Neoplasms; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Taxoids; Time Factors; Tumor Cells, Cultured; Vinblastine; Vinorelbine; Vulvar Neoplasms

2000