Page last updated: 2024-08-21

quinazolines and dpc 961

quinazolines has been researched along with dpc 961 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aubry, AF; Gray, V; Hobson, T; Rabel, S; Sebastian, D; Xie, M; Xu, JQ1
Cao, K; Chen, H; Chen, S; Du, A; Espina, R; Gan, LS; Mutlib, A; Nemeth, G; Prakash, S; Shockcor, J1
Aubry, AF; Boucher, RJ; Sebastian, DS; Williams, RC1
Aubry, AF; Edwards, JF; Joshi, AS; Williams, RC1
Bacheler, LT; Chidester, DR; Cocuzza, AJ; Cordova, BC; Diamond, S; Erickson-Viitanen, SK; Jeffrey, S; Klabe, RM; Ko, SS; Rodgers, JD; Weigelt, CA1
Aungst, BJ; Bindra, DS; Nguyen, NH; Taylor, NJ1
Confalone, PN; Davis, WP; Magnus, NA; Parsons, RL; Patel, M; Storace, L; Wood, CC1
Caballero, J; Castro, EA; Duchowicz, PR; Fernández, FM; Fernández, M1

Other Studies

8 other study(ies) available for quinazolines and dpc 961

ArticleYear
In-use testing of extemporaneously prepared suspensions of second generation non-nucleoside reversed transcriptase inhibitors in support of phase I clinical studies.
    Journal of pharmaceutical and biomedical analysis, 2000, Aug-15, Volume: 23, Issue:2-3

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Pharmaceutical Preparations; Quinazolines; Quinazolinones; Quinolones; Reverse Transcriptase Inhibitors; Solubility; Spectrophotometry, Ultraviolet

2000
Characterization of novel glutathione adducts of a non-nucleoside reverse transcriptase inhibitor, (S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3, 4-dihydro-2(1H)-quinazolinone (DPC 961), in rats. Possible formation of an oxirene metabolic inte
    Chemical research in toxicology, 2000, Volume: 13, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Epoxy Compounds; Female; Glutathione; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Protein Binding; Quinazolines; Quinazolinones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors

2000
Column selection and method development for the determination of the enantiomeric purity of investigational non-nucleoside reverse transcriptase inhibitors.
    Chirality, 2001, May-05, Volume: 13, Issue:4

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; HIV Infections; Humans; Quinazolines; Quinazolinones; Reproducibility of Results; Reverse Transcriptase Inhibitors; Stereoisomerism

2001
Chiral analysis of drug substance in clinical plasma extracts using achiral HPLC with circular dichroism detection.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 25, Issue:3-4

    Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Humans; Quinazolines; Quinazolinones; Stereoisomerism; Ultraviolet Rays

2001
4,1-Benzoxazepinone analogues of efavirenz (Sustiva) as HIV-1 reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 2001, Jun-04, Volume: 11, Issue:11

    Topics: Alkynes; Animals; Benzoxazines; Cyclopropanes; HIV Reverse Transcriptase; Humans; Macaca mulatta; Oxazines; Protein Binding; Quinazolines; Quinazolinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2001
Formulation and food effects on the oral absorption of a poorly water soluble, highly permeable antiretroviral agent.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:6

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Biological Availability; Chemistry, Pharmaceutical; Dogs; Female; Food-Drug Interactions; Models, Animal; Particle Size; Quinazolines; Quinazolinones; Solubility; Tablets; Water

2002
General scope of 1,4-diastereoselective additions to a 2(3H)-quinazolinone: practical preparation of HIV therapeutics.
    The Journal of organic chemistry, 2003, Feb-07, Volume: 68, Issue:3

    Topics: Anti-HIV Agents; Catalysis; Combinatorial Chemistry Techniques; HIV; Humans; Molecular Structure; Quinazolines; Quinazolinones; Reverse Transcriptase Inhibitors; Spectrophotometry, Infrared; Stereoisomerism

2003
QSAR for non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry, 2006, Sep-01, Volume: 14, Issue:17

    Topics: Alkynes; Benzoxazines; Combinatorial Chemistry Techniques; Cyclopropanes; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Mutation; Oxazines; Quantitative Structure-Activity Relationship; Quinazolines; Quinazolinones; Reverse Transcriptase Inhibitors

2006