quinazolines has been researched along with dinoprostone in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.36) | 18.7374 |
| 1990's | 4 (9.09) | 18.2507 |
| 2000's | 21 (47.73) | 29.6817 |
| 2010's | 14 (31.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gray, SJ; Heptinstall, S | 1 |
| Huttemeier, PC; Melvin, C; Morel, DR; Nguyenduy, T; Robinson, DR; Skoskiewicz, MJ; Zapol, WM | 1 |
| Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H | 1 |
| Abdel-Latif, AA; Yousufzai, SY | 1 |
| Dyer, RD; Huttner, JJ; Mulrow, PJ; Tan, SY | 1 |
| Pipili, E; Poyser, NL | 1 |
| Alvarez, R; Conti, M; Eglen, RM; Sette, C; Shelton, ER; Wilhelm, R; Yang, D | 1 |
| Baba, A; Kawamura, N; Makino, H; Ohta, Y; Sohda, T; Taketomi, S | 1 |
| Ahola, H; Carlstedt-Duke, J; Modéer, T; Yucel-Lindberg, T | 1 |
| Ikeda, M; Ishihara, T; Iwaki, K; Kohno, K; Kurimoto, M; Ushio, S | 1 |
| Alcaraz, MJ; Gonzalez-Tejero, A; Molina, P; Rioja, I; Tárraga, A; Terencio, MC; Ubeda, A | 1 |
| Baatar, D; Pai, R; Pavelka, M; Soreghan, B; Szabo, IL; Tarnawski, AS | 1 |
| Aga, M; Ikeda, M; Ishihara, T; Iwaki, K; Kimoto, T; Koya-Miyata, S; Kunikata, T; Kurimoto, M; Micallef, MJ; Ushio, S | 1 |
| Kim, SS; Lee, JY; Lee, SK; Lee, YS; Min, HY; Park, JH | 1 |
| Bagnato, A; Di Castro, V; Elia, G; Natali, PG; Rosanò, L; Spinella, F | 1 |
| Neufeld, AH; Zhang, X | 1 |
| Bao, Y; Ding, YB; Li, XY; Shi, RH; Tong, JD; Wang, XH; Wu, J; Xiao, WM; Yan, ZG; Yang, JG; Zhang, GX | 1 |
| Altundag, K; Altundag, O; Boruban, C; Silay, YS | 1 |
| Brown, DA; Canning, MT; Galvin, JW; Nay, SL; Peña, AV; Yarosh, DB | 1 |
| Cai, XF; Choi, YH; Kim, HP; Kim, YS; Lee, JJ; Shin, EM | 1 |
| Kawakami, T; Olsson, T; Yucel-Lindberg, T | 1 |
| Aasrum, M; Christoffersen, T; Dajani, OF; Guren, TK; Lilleby, P; Meisdalen, K; Sandnes, D; Thoresen, GH; Tveteraas, IH | 1 |
| Chen, X; Li, N; Newman, RA; Sood, S; Sun, Z; Yang, CS; Yang, P | 1 |
| Hu, Z; Wu, D | 1 |
| Hashizume, H; Kamio, N; Matsushima, K; Nakao, S; Sugiya, H | 1 |
| Ahmad, A; Ali, S; Banerjee, S; El-Rayes, BF; Philip, PA; Sarkar, FH | 1 |
| Chang, YL; Guh, JH; Huang, DY; Liao, CH; Liu, YN; Pan, SL; Peng, CY; Teng, CM | 1 |
| Ali, S; Gadgeel, SM; Philip, PA; Sarkar, FH; Wozniak, A | 1 |
| Kim, YM; Park, SY; Pyo, H | 1 |
| Chen, CL; Lo, HM; Tsai, YJ; Wu, PH; Wu, WB | 1 |
| Hudish, TM; Karoor, V; Keith, RL; Le, M; Miller, YE; Mozer, AB | 1 |
| Dumont, Y; Ma, W; Quirion, R; Vercauteren, F | 1 |
| Glenn, JR; Heptinstall, S; Iyu, D; White, AE | 1 |
| Banerjee, S; Bose, D; Chatterjee, N; Chattopadhyay, D; Das, S; Saha, KD | 1 |
| Aasrum, M; Christoffersen, T; Dajani, O; Guren, T; Müller, KM; Sandnes, D; Tveteraas, IH; Ødegård, J | 1 |
| Al-Omar, MA; Al-Salahi, RA; Alanazi, AM; Fouda, MM; Gamal-Eldeen, AM; Marzouk, MA | 1 |
| Fernández-Martínez, AB; Lucio Cazaña, FJ | 1 |
| Chae, IG; Chun, KS; Kwon, TK; Min, KJ; Woo, SM | 1 |
| Gong, S; Ma, C; Wang, S; Zhao, Z | 1 |
| Cha, JH; Cho, NC; Kim, D; Kim, H; Kim, T; Kim, YK; Kwak, J; Lee, J; Lee, KT; No, KT; Pae, AN; Park, KD; Seo, SH; Shin, JS | 1 |
| Fulton, AM; Kochel, TJ; Kundu, N; Ma, X; Reader, JC | 1 |
| Feng, NP; He, ZH; Li, Z; Xia, Q; Zhang, HY; Zhang, K; Zhang, YT; Zhao, JH | 1 |
| Bordignon, V; da Rosa, PRA; De Cesaro, MP; Duggavathi, R; Gonçalves, PBD; Pereira Dau, AM | 1 |
| Akin, JW; Brännström, M; Choi, Y; Curry, TE; Jo, M; Rosewell, KL | 1 |
1 trial(s) available for quinazolines and dinoprostone
| Article | Year |
|---|---|
Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine.
Topics: Administration, Cutaneous; Adult; Alkaloids; Anti-Inflammatory Agents; Biomimetics; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Erythema; Evodia; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; Indole Alkaloids; Keratinocytes; Middle Aged; Nicotinic Acids; Nitric Oxide; Plant Extracts; Quinazolines; Skin; Time Factors; Ultraviolet Rays | 2006 |
43 other study(ies) available for quinazolines and dinoprostone
| Article | Year |
|---|---|
Interactions between prostaglandin E2 and inhibitors of platelet aggregation which act through cyclic AMP.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Cyclic AMP; Dinoprostone; Humans; Imidazoles; In Vitro Techniques; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Quinazolines | 1991 |
Dose-dependent effects of a pyridoquinazoline thromboxane synthetase inhibitor on arachidonic acid metabolites and hemodynamics during E. coli endotoxemia in anesthetized sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Dinoprostone; Endotoxins; Escherichia coli; Hemodynamics; Kinetics; Lymph; Prostaglandins E; Prostaglandins F; Pulmonary Artery; Quinazolines; Sheep; Thromboxane B2; Thromboxane-A Synthase; Toxemia; Vascular Resistance | 1987 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
The effects of alpha 1-adrenergic and muscarinic cholinergic stimulation on prostaglandin release by rabbit iris.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Calcimycin; Calcium; Dinoprostone; Female; Inositol; Iris; Kinetics; Male; Microsomes; Norepinephrine; Prazosin; Prostaglandins E; Quinazolines; Rabbits; Tubocurarine; Yohimbine | 1984 |
Prostaglandin synthesis by vascular smooth muscle cells is stimulated by bradykinin, prazosin and hydralazine.
Topics: Animals; Aorta; Bradykinin; Cells, Cultured; Dinoprostone; Guinea Pigs; Hydralazine; Muscle, Smooth, Vascular; Prazosin; Prostaglandins; Prostaglandins E; Quinazolines | 1981 |
Differential effects of prazosin and rauwolsin on the release of prostaglandins I2 and E2 from the perfused mesenteric arterial bed of the rabbit following nerve stimulation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Electric Stimulation; Epoprostenol; Indomethacin; Male; Mesenteric Arteries; Norepinephrine; Phenylephrine; Prazosin; Prostaglandins; Prostaglandins E; Quinazolines; Rabbits; Vasoconstriction; Yohimbine | 1982 |
Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Enzyme Activation; Humans; Intracellular Fluid; Isoenzymes; Kinetics; Magnesium; Monocytes; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Precipitin Tests; Pyridazines; Quinazolines; Recombinant Proteins; Sensitivity and Specificity; Tumor Cells, Cultured | 1995 |
Studies on disease-modifying antirheumatic drugs: synthesis of novel quinoline and quinazoline derivatives and their anti-inflammatory effect.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Bone Resorption; Dinoprostone; Disease Models, Animal; Female; Magnetic Resonance Spectroscopy; Male; Pregnancy; Quinazolines; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship | 1996 |
Involvement of tyrosine kinases on cyclooxygenase expression and prostaglandin E2 production in human gingival fibroblasts stimulated with interleukin-1beta and epidermal growth factor.
Topics: Benzoquinones; Cells, Cultured; Child; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Interleukin-1; Isoenzymes; Lactams, Macrocyclic; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Quinazolines; Quinones; Rifabutin; RNA, Messenger; Sulfonamides; Time Factors | 1999 |
Tryptanthrin inhibits nitric oxide and prostaglandin E(2) synthesis by murine macrophages.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cyclooxygenase 2; Dinoprostone; Isoenzymes; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Quinazolines | 2000 |
Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives.
Topics: Alkaloids; Animals; Brassicaceae; Cells, Cultured; Chromatography, Thin Layer; Dinoprostone; Free Radical Scavengers; Humans; Inflammation; Inflammation Mediators; Inhibitory Concentration 50; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neutrophils; Nitric Oxide Synthase; Plants, Medicinal; Quinazolines; Structure-Activity Relationship; Xanthine Oxidase | 2001 |
Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy.
Topics: Animals; Cell Line; Colonic Neoplasms; Dinoprostone; Enzyme Inhibitors; ErbB Receptors; Gastric Mucosa; Genes, src; Humans; Hypertrophy; MAP Kinase Signaling System; Matrix Metalloproteinases; Mitogen-Activated Protein Kinase 1; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Transcriptional Activation; Tyrphostins | 2002 |
The natural plant product tryptanthrin ameliorates dextran sodium sulfate-induced colitis in mice.
Topics: Animals; Biological Factors; Colitis; Colon; Cytokines; Dextran Sulfate; Dinoprostone; Drugs, Chinese Herbal; Female; Gene Expression; Mice; Mice, Inbred C57BL; Mitogens; Nitric Oxide; Phytotherapy; Polygonum; Quinazolines; Spleen; Time Factors | 2002 |
Styrylquinazolines: a new class of inhibitors on prostaglandin E2 production in lipopolysaccharide-activated macrophage cells.
Topics: Cell Line; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Isoenzymes; Lipopolysaccharides; Macrophage Activation; Macrophages; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Quinazolines; Resveratrol; Stilbenes; Styrenes | 2004 |
Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Induction; ErbB Receptors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Protein Kinase Inhibitors; Pyridines; Quinazolines; Receptor, Endothelin A; Signal Transduction; Transcriptional Activation; Tyrphostins | 2004 |
Activation of the epidermal growth factor receptor in optic nerve astrocytes leads to early and transient induction of cyclooxygenase-2.
Topics: Animals; Astrocytes; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique, Indirect; Nitrobenzenes; Optic Nerve; Optic Nerve Injuries; Prostaglandin-Endoperoxide Synthases; Protein Tyrosine Phosphatases; Quinazolines; Rats; Rats, Wistar; Sulfonamides; Tyrphostins | 2005 |
PGE2 up-regulates vascular endothelial growth factor expression in MKN28 gastric cancer cells via epidermal growth factor receptor signaling system.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Immunoprecipitation; Mitogen-Activated Protein Kinase 1; Oxytocics; Phosphorylation; Quinazolines; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Transcriptional Activation; Tumor Cells, Cultured; Tyrphostins; Up-Regulation; Vascular Endothelial Growth Factor A | 2005 |
Cross-talk between cyclooxygenase-2 and epidermal growth factor receptor in non-small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2; Dinoprostone; Disease Progression; Docetaxel; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lung Neoplasms; Pyrazoles; Quinazolines; Signal Transduction; Sulfonamides; Taxoids; Treatment Outcome | 2005 |
Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Calcimycin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Leukotriene C4; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophages; Mice; NF-kappa B; Plant Extracts; Quinazolines | 2006 |
Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.
Topics: Arachidonic Acid; Blotting, Western; Cells, Cultured; Child; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Imidazoles; Indoles; Interleukin-1beta; Intramolecular Oxidoreductases; Maleimides; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin D2; Prostaglandin-E Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2006 |
Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Cells, Cultured; Culture Media, Serum-Free; Cyclin D; Cyclins; Dinoprostone; DNA; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Expression Regulation; Hepatocytes; Liver Neoplasms; Male; Pertussis Toxin; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins | 2008 |
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Dinoprostone; ErbB Receptors; Humans; Male; Mouth Mucosa; Mouth Neoplasms; Quinazolines; Receptor, ErbB-2 | 2008 |
Rutaecarpine induces chloride secretion across rat isolated distal colon.
Topics: Animals; Biological Transport; Chloride Channels; Chlorides; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; In Vitro Techniques; Indole Alkaloids; Potassium Channels; Quinazolines; Rats | 2008 |
Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp.
Topics: Adult; Calcium; Cells, Cultured; Dental Pulp; Dinoprostone; Fibrinolysin; Humans; Inflammation; Interleukin-8; Peptides; Pyrroles; Quinazolines; Receptor, PAR-1; RNA, Messenger | 2008 |
Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dinoprostone; DNA, Complementary; DNA, Neoplasm; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Fluorescence; Humans; Indoles; Mice; NF-kappa B; Pancreatic Neoplasms; Protein Binding; Pyrazoles; Quinazolines; Signal Transduction; Sulfonamides; Transfection; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2008 |
Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1alpha accumulation in RAW264.7.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Camptothecin; Cell Hypoxia; Cell Line; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Pyrrolidines; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Thiocarbamates | 2009 |
Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Genistein; Humans; Lung Neoplasms; NF-kappa B; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines | 2009 |
Cyclooxygenase-2 (COX-2) negatively regulates expression of epidermal growth factor receptor and causes resistance to gefitinib in COX-2-overexpressing cancer cells.
Topics: Cyclooxygenase 2; Dinoprostone; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HCT116 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Quinazolines; RNA, Messenger; Transcription, Genetic | 2009 |
Thrombin induces cyclooxygenase-2 expression and prostaglandin E2 release via PAR1 activation and ERK1/2- and p38 MAPK-dependent pathway in murine macrophages.
Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Enzyme Inhibitors; Epoprostenol; Flavonoids; Imidazoles; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrroles; Quinazolines; Receptor, PAR-1; Signal Transduction; Thrombin; Thromboxane A2 | 2009 |
Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.
Topics: Adenoma; Animals; Antineoplastic Agents; Cadherins; Cytochrome P-450 Enzyme System; Dinoprostone; Epoprostenol; ErbB Receptors; Female; Gefitinib; Intramolecular Oxidoreductases; Lung Neoplasms; Male; Mice; Mice, Transgenic; Protein Kinase Inhibitors; Quinazolines; Rats; Signal Transduction | 2010 |
Lipopolysaccharide induces calcitonin gene-related peptide in the RAW264.7 macrophage cell line.
Topics: Animals; Antibodies; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; Cell Line; Chemokines; Cycloheximide; Cyclooxygenase 2 Inhibitors; Cytokines; Dactinomycin; Dinoprostone; Enzyme Inhibitors; I-kappa B Proteins; Interleukin-1beta; Interleukin-6; Intracellular Signaling Peptides and Proteins; Kinetics; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Nerve Growth Factor; Nitriles; Nitrobenzenes; Peptide Fragments; Piperazines; Quinazolines; Receptor Activity-Modifying Proteins; Receptor, trkA; Receptors, Calcitonin; Sulfonamides; Sulfones; Toll-Like Receptor 4 | 2010 |
PGE(2) reverses G(s)-mediated inhibition of platelet aggregation by interaction with EP3 receptors, but adds to non-G(s)-mediated inhibition of platelet aggregation by interaction with EP4 receptors.
Topics: Acrylamides; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Dinoprostone; Humans; Microfilament Proteins; Naphthalenes; Phenylbutyrates; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Antagonists; Quinazolines; Receptors, G-Protein-Coupled; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfones | 2012 |
Exploring the anti-inflammatory activity of a novel 2-phenylquinazoline analog with protection against inflammatory injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Capillary Permeability; Carrageenan; Cell Line; Cell Survival; Cytokines; Dinoprostone; Female; Formaldehyde; Inflammation; Lipopolysaccharides; Liver; Liver Function Tests; Macrophages; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; NF-kappa B; Nitric Oxide; Quinazolines; Shock, Septic; Survival | 2012 |
Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Rats; Signal Transduction | 2012 |
Cytotoxicity and anti-inflammatory activity of methylsulfanyl-triazoloquinazolines.
Topics: Animals; Anti-Inflammatory Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dinoprostone; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Quinazolines; Tumor Necrosis Factor-alpha | 2013 |
Epidermal growth factor receptor transactivation by intracellular prostaglandin E2-activated prostaglandin E2 receptors. Role in retinoic acid receptor-β up-regulation.
Topics: Cell Line, Tumor; Dinoprostone; Enzyme Inhibitors; ErbB Receptors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Keratolytic Agents; Kidney Tubules, Proximal; Phosphorylation; Quinazolines; Receptors, Prostaglandin E; Receptors, Retinoic Acid; Transcriptional Activation; Tretinoin; Tyrphostins; Up-Regulation; Vascular Endothelial Growth Factor A | 2013 |
Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways.
Topics: Alprostadil; Antioxidants; Benzodioxoles; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; HCT116 Cells; HT29 Cells; Humans; Integrases; Kidney Neoplasms; Phosphorylation; Prostaglandin Antagonists; Quinazolines; Receptors, Prostaglandin E, EP2 Subtype; RNA Interference; RNA, Small Interfering; Signal Transduction; Silymarin; src-Family Kinases; STAT3 Transcription Factor; Wound Healing; Xanthones | 2015 |
Effect and mechanism of evodiamine against ethanol-induced gastric ulcer in mice by suppressing Rho/NF-кB pathway.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Catalase; Cell Line; Dinoprostone; Ethanol; Female; Gastric Mucosa; Glutathione; Humans; Interleukin-6; Malondialdehyde; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Quinazolines; Stomach; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2015 |
Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.
Topics: Amination; Animals; Anti-Inflammatory Agents; Cell Line; Dinoprostone; Interleukin-1beta; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Quinazolines; Receptor, PAR-2; Sepsis; Tumor Necrosis Factor-alpha | 2015 |
Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Movement; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxyprostaglandin Dehydrogenases; MCF-7 Cells; Mice, Inbred BALB C; Mice, SCID; Multidrug Resistance-Associated Proteins; Neoplasm Metastasis; Organic Anion Transporters; Propionates; Quinazolines; Quinolines; Receptors, Prostaglandin E, EP4 Subtype; RNA Interference; Signal Transduction; Time Factors; Transfection; Triple Negative Breast Neoplasms; Tumor Microenvironment; Tyrphostins | 2017 |
Co-delivery of evodiamine and rutaecarpine in a microemulsion-based hyaluronic acid hydrogel for enhanced analgesic effects on mouse pain models.
Topics: Analgesics; Animals; Dinoprostone; Drug Carriers; Emulsions; Guinea Pigs; Hyaluronic Acid; Hydrogels; Indole Alkaloids; Interleukin-6; Mice; Pain; Quinazolines; Skin Absorption; Tumor Necrosis Factor-alpha | 2017 |
Reversible meiotic arrest of bovine oocytes by EGFR inhibition and follicular hemisections.
Topics: Angiotensin II; Animals; Cattle; Cell Cycle Checkpoints; Cumulus Cells; Dinoprostone; Embryo Culture Techniques; ErbB Receptors; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Granulosa Cells; In Vitro Oocyte Maturation Techniques; Meiosis; Oocytes; Ovarian Follicle; Quinazolines; RNA, Messenger; Signal Transduction; Tyrphostins | 2017 |
FOS, a Critical Downstream Mediator of PGR and EGF Signaling Necessary for Ovulatory Prostaglandins in the Human Ovary.
Topics: Adult; Benzophenones; Cells, Cultured; Chorionic Gonadotropin; Dinoprostone; Epidermal Growth Factor; Female; Humans; Isoxazoles; Mifepristone; Ovarian Follicle; Ovulation; Primary Cell Culture; Progesterone; Proto-Oncogene Proteins c-fos; Quinazolines; Receptors, Progesterone; RNA, Small Interfering; Signal Transduction; Tyrphostins; Up-Regulation | 2018 |