quinazolines has been researched along with dimethylenastron in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V | 1 |
| Huo, L; Li, M; Liu, J; Liu, M; Yu, H; Zhou, J | 1 |
| Castedo, M; Jemaá, M; Kepp, O; Kroemer, G; Métivier, D; Rello-Varona, S; Senovilla, L; Vitale, I | 1 |
| Dallinger, D; Kaan, HY; Kappe, CO; Kozielski, F; Prokopcová, H; Rath, O; Ulaganathan, V | 1 |
| Giannis, A; Grisanti, S; Lüke, J; Lüke, M; Merz, H; Nassar, K; Tura, A | 1 |
| Kenny, AE; Lee, K; Rieder, CL | 1 |
| Li, DW; Liu, M; Luo, YG; Shi, XJ; Sun, XD; Sun, XO; Wu, XJ; Yao, CF; Yu, HY; Zhou, J | 1 |
| DeBonis, S; Garcia-Saez, I; Indorato, RL; Kozielski, F; Skoufias, DA | 1 |
| Becker, J; Bicknell, R; Bikfalvi, A; Exertier, P; Franco, M; Godard, V; Hagedorn, M; Herbert, J; Javerzat, S; Nivelles, O; Ormenese, S; Pineau, R; Platonova, N; Pujol, N; Wang, B; Wilting, J; Winandy, M | 1 |
| Sun, L; Sun, X; Xie, S; Yu, H; Zhong, D | 1 |
10 other study(ies) available for quinazolines and dimethylenastron
| Article | Year |
|---|---|
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
Validating the mitotic kinesin Eg5 as a therapeutic target in pancreatic cancer cells and tumor xenografts using a specific inhibitor.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Female; Humans; Kinesins; Mice; Mice, Nude; Pancreatic Neoplasms; Quinazolines; Thiones; Xenograft Model Antitumor Assays | 2008 |
Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Gene Knockdown Techniques; Humans; Kinesins; Mitosis; Neoplasms; Polyploidy; Quinazolines; RNA, Small Interfering; Thiones | 2009 |
Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol.
Topics: Antimitotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Resistance, Multiple; Humans; Kinesins; Models, Molecular; Protein Conformation; Protein Structure, Tertiary; Pyrimidines; Quinazolines; Stereoisomerism; Structure-Activity Relationship; Thiones | 2010 |
The effect of adjuvant dimethylenastron, a mitotic Kinesin Eg5 inhibitor, in experimental glaucoma filtration surgery.
Topics: Animals; Antimitotic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Filtering Surgery; Inflammation; Injections, Intraocular; Intraocular Pressure; Postoperative Complications; Quinazolines; Rabbits; Thiones; Time Factors; Wound Healing | 2010 |
Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells.
Topics: Caspase Inhibitors; Caspases; Cell Line; Genes, cdc; Humans; Mitosis; Mitotic Index; Nocodazole; Quinazolines; Retinal Pigment Epithelium; RNA, Small Interfering; Spindle Apparatus; Thiones | 2011 |
Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5.
Topics: Allosteric Regulation; Cell Line, Tumor; Cell Movement; Humans; Kinesins; Neoplasm Invasiveness; Pancreatic Neoplasms; Quinazolines; Thiones | 2011 |
STLC-resistant cell lines as tools to classify chemically divergent Eg5 targeting agents according to their mode of action and target specificity.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Allosteric Site; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cysteine; Drug Resistance, Neoplasm; Humans; Kinesins; M Phase Cell Cycle Checkpoints; Point Mutation; Quinazolines; Thiadiazoles; Thiones | 2013 |
Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5.
Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Gene Expression; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Kinesins; Mice; Mitosis; Neovascularization, Pathologic; Quinazolines; Recombinant Proteins; Thiones; Vascular Endothelial Growth Factor A; Zebrafish | 2013 |
Significant decrease of ADP release rate underlies the potent activity of dimethylenastron to inhibit mitotic kinesin Eg5 and cancer cell proliferation.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Humans; Kinesins; Mitosis; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quinazolines; Thiones | 2014 |