Page last updated: 2024-08-21

quinazolines and digoxin

quinazolines has been researched along with digoxin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's4 (25.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Atwell, RB1
Chiba, S; Katsuyama, Y; Tada, A; Tsukada, M; Zenda, H1
Gokhale, RD; Plunkett, LM; Tackett, RL; Vallner, JJ1
Silke, B; Taylor, SH1
Blaufox, MD; Lee, HB; Scharf, SC; Wexler, JP1
Gale, EV; Kuan, P; Reuben, SR; Wilde, PM1
Benzing, G; Dillon, TR; Janos, GG; Kaplan, S; Meyer, RA1
Clarke, GM; Cope, GD; Hockings, BE; Taylor, RR1
Fantini, F; Franchi, F; Michelucci, A; Morace, G; Porciani, MC1
Abbara, C; Bonhomme-Faivre, L; Chu, C; Farinotti, R; Gonin, P; Noël-Hudson, MS; Thomas-Bourgneuf, L1
Brand, T; Friedrich, C; Graefe-Mody, EU; Ring, A; Sennewald, R; Woerle, HJ1
Ma, G; Wang, H; Yan, J; Yang, Q; Zhang, X; Zhu, X1
Johansson, S; Leese, PT; Li, Y; Lisbon, E; Martin, P; Mathews, D; Oliver, S; Read, J; Steinberg, M1
Arya, N; Bang, YJ; Beyer, J; Botbyl, J; Briley, LP; Cartee, L; Chu, Q; Chung, HC; Dar, MM; Koch, KM; Smith, DA; White, JH1
Erb-Zohar, K; Kropeit, D; McCormick, D; Rübsamen-Schaeff, H; Scheuenpflug, J; Stobernack, HP; Theis, JGW; Zimmermann, H1
Abdulrasool, LI; Endres, CJ; Lee, A; Mayor, JG; Rustia, EL; Sun, H; Topletz-Erickson, A; Walker, L1

Trials

3 trial(s) available for quinazolines and digoxin

ArticleYear
Evaluation of the pharmacokinetic interaction after multiple oral doses of linagliptin and digoxin in healthy volunteers.
    European journal of drug metabolism and pharmacokinetics, 2011, Volume: 36, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Cross-Over Studies; Digoxin; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Humans; Linagliptin; Male; Middle Aged; Purines; Quinazolines; Young Adult

2011
Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine.
    Clinical pharmacokinetics, 2014, Volume: 53, Issue:9

    Topics: Adolescent; Adult; Area Under Curve; Digoxin; Drug Interactions; Female; Humans; Male; Metformin; Midazolam; Middle Aged; Omeprazole; Piperidines; Quinazolines; Ranitidine; Young Adult

2014
Effect of lapatinib on oral digoxin absorption in patients.
    Clinical pharmacology in drug development, 2015, Volume: 4, Issue:6

    Topics: Administration, Oral; Adult; Alberta; Antineoplastic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cardiotonic Agents; Cross-Over Studies; Digoxin; Drug Interactions; Female; Gastrointestinal Absorption; Half-Life; Humans; Lapatinib; Metabolic Clearance Rate; Middle Aged; Protein Kinase Inhibitors; Quinazolines; Risk Assessment; Seoul

2015

Other Studies

13 other study(ies) available for quinazolines and digoxin

ArticleYear
The use of alpha blockade in the treatment of congestive heart failure associated with dirofilariasis and mitral valvular incompetence.
    The Veterinary record, 1979, Feb-10, Volume: 104, Issue:6

    Topics: Animals; Digoxin; Dirofilariasis; Dog Diseases; Dogs; Female; Furosemide; Heart Failure; Male; Mitral Valve Insufficiency; Prazosin; Quinazolines

1979
Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.
    Heart and vessels, 1987, Volume: 3, Issue:3

    Topics: Animals; Arteries; Blood Proteins; Cardenolides; Digoxin; Dogs; Ear, External; Epinephrine; Humans; Hypertension; In Vitro Techniques; Mesenteric Arteries; Ouabain; Phentolamine; Potassium Chloride; Quinazolines; Saponins; Vasoconstrictor Agents; Verapamil

1987
Prazosin alters free and total plasma digoxin levels in dogs.
    American heart journal, 1985, Volume: 109, Issue:4

    Topics: Animals; Digoxin; Dogs; Drug Interactions; Kinetics; Myocardial Contraction; Prazosin; Quinazolines; Radioimmunoassay

1985
The pharmacokinetic, pharmacodynamic and haemodynamic effects of acute and chronic alpha-adrenoceptor blockade in chronic heart failure.
    Annals of the Academy of Medicine, Singapore, 1981, Volume: 10, Issue:4 Suppl

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Digoxin; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Kinetics; Male; Middle Aged; Prazosin; Quinazolines

1981
Pharmacologic alterations in Tc-99m binding by red blood cells: concise communication.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1983, Volume: 24, Issue:5

    Topics: Animals; Blood Pressure; Captopril; Digoxin; Drug Interactions; Erythrocytes; Female; Hematocrit; Hypertension; Prazosin; Proline; Protein Binding; Quinazolines; Rats; Rats, Inbred Strains; Technetium; Time Factors

1983
Haemodynamic effects of prazosin in CHF.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 652

    Topics: Cardiac Catheterization; Cardiac Output; Digoxin; Drug Therapy, Combination; Furosemide; Heart Failure; Hemodynamics; Humans; Prazosin; Quinazolines

1981
Vasodilator therapy for congestive heart failure.
    The Journal of pediatrics, 1980, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Digoxin; Diuretics; Drug Therapy, Combination; Ferricyanides; Heart Failure; Humans; Infant; Nitroprusside; Prazosin; Quinazolines

1980
Comparison of vasodilator drug prazosin with digoxin in aortic regurgitation.
    British heart journal, 1980, Volume: 43, Issue:5

    Topics: Adult; Aortic Valve Insufficiency; Digoxin; Female; Hemodynamics; Humans; Male; Middle Aged; Prazosin; Quinazolines; Time Factors

1980
[Evaluation of long-term treatment with isosorbide dinitrate and prazosin in cardiac insufficiency].
    La Clinica terapeutica, 1980, Apr-15, Volume: 93, Issue:1

    Topics: Adult; Aged; Digoxin; Drug Evaluation; Female; Furosemide; Heart Failure; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Prazosin; Quinazolines; Time Factors

1980
Disposition of everolimus in mdr1a-/1b- mice and after a pre-treatment of lapatinib in Swiss mice.
    Biochemical pharmacology, 2009, May-15, Volume: 77, Issue:10

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Blotting, Western; Digoxin; Everolimus; Female; Intestinal Mucosa; Intestines; Lapatinib; Mice; Mice, Knockout; Quinazolines; Sirolimus; Substrate Specificity; Tissue Distribution

2009
Transport characteristics of tryptanthrin and its inhibitory effect on P-gp and MRP2 in Caco-2 cells.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2011, Volume: 14, Issue:3

    Topics: Antitubercular Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Diffusion; Digoxin; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Enzyme Inhibitors; Glyburide; Humans; Hypoglycemic Agents; Intestinal Mucosa; Intestines; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Permeability; Quinazolines

2011
The Effect of Oral Letermovir Administration on the Pharmacokinetics of a Single Oral Dose of P-Glycoprotein Substrate Digoxin in Healthy Volunteers.
    Clinical pharmacology in drug development, 2022, Volume: 11, Issue:1

    Topics: Acetates; Administration, Oral; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clinical Trials, Phase I as Topic; Digoxin; Healthy Volunteers; Humans; Quinazolines; United States

2022
Evaluation of Safety and Clinically Relevant Drug-Drug Interactions with Tucatinib in Healthy Volunteers.
    Clinical pharmacokinetics, 2022, Volume: 61, Issue:10

    Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inducers; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Digoxin; Drug Interactions; Gemfibrozil; Healthy Volunteers; Humans; Itraconazole; Midazolam; Oxazoles; Pyridines; Quinazolines; Rifampin; Tolbutamide

2022