Page last updated: 2024-08-21

quinazolines and cyclopamine

quinazolines has been researched along with cyclopamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batra, SK; Depreux, P; Hénichart, JP; Lin, MF; Mimeault, M; Moniaux, N; Moore, E1
Bonde, P; Broor, A; Dhara, S; Duncan, M; Feldmann, G; Harmon, JW; Maitra, A; Marti, G; Montgomery, E; Sui, G; Wang, J1
Batra, SK; Depreux, P; Henichart, JP; Johansson, SL; Lin, MF; Mimeault, M; Moore, E; Vankatraman, G1
Hu, WG; Liu, T; Wang, CY; Xiong, JX1
Batra, SK; Depreux, P; Hauke, R; Henichart, JP; Lin, MF; Mehta, PP; Mimeault, M1
Batra, SK; Depreux, P; Henichart, JP; Johansson, SL; Mimeault, M1
Behrman, SW; Chitkara, D; Danquah, M; Kumar, N; Kumar, V; Mahato, RI; Singh, S1
Airiau, K; Avril, T; Belaud-Rotureau, MA; Belloc, F; Dugay, F; Eimer, S; Quillien, V1
Che, J; Shen, XJ; Sun, KK; Wu, XY; Yang, D; Zhao, H; Zhong, N1
Bahra, M; Boas-Knoop, S; Bova, R; Bradtmöller, M; Guse, K; Kamphues, C; Koch, A; Lippert, S; Neuhaus, P; Riedlinger, D; Sauer, IM; Seehofer, D1
Armstrong, BE; Henner, A; Stankunas, K; Stewart, S1

Other Studies

11 other study(ies) available for quinazolines and cyclopamine

ArticleYear
Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells.
    International journal of cancer, 2006, Feb-15, Volume: 118, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Proliferation; DNA Damage; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Hedgehog Proteins; Humans; Male; Prostatic Neoplasms; Quinazolines; Signal Transduction; Trans-Activators; Tumor Cells, Cultured; Veratrum Alkaloids

2006
Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model.
    The Journal of surgical research, 2006, Volume: 134, Issue:1

    Topics: Animals; Apoptosis; Cell Line, Tumor; ErbB Receptors; Esophageal Neoplasms; Gefitinib; Hedgehog Proteins; Male; MAP Kinase Signaling System; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Trans-Activators; Veratrum Alkaloids

2006
Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Cytochromes c; Docetaxel; ErbB Receptors; Gefitinib; Hedgehog Proteins; Humans; Immunohistochemistry; Male; Membrane Potential, Mitochondrial; Neoplasm Invasiveness; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Quinazolines; Signal Transduction; Taxoids; Tumor Cells, Cultured; Veratrum Alkaloids

2007
Blockade of sonic hedgehog signal pathway enhances antiproliferative effect of EGFR inhibitor in pancreatic cancer cells.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:8

    Topics: Apoptosis; Cell Cycle; Cell Proliferation; ErbB Receptors; Gefitinib; Hedgehog Proteins; Humans; Pancreatic Neoplasms; Quinazolines; Signal Transduction; Veratrum Alkaloids

2007
Improvement of cytotoxic effects induced by mitoxantrone on hormone-refractory metastatic prostate cancer cells by co-targeting epidermal growth factor receptor and hedgehog signaling cascades.
    Growth factors (Chur, Switzerland), 2007, Volume: 25, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Synergism; ErbB Receptors; Gefitinib; Hedgehog Proteins; Humans; Hydrogen Peroxide; Male; Membrane Potential, Mitochondrial; Mitoxantrone; Neoplasm Invasiveness; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Quinazolines; Signal Transduction; Veratrum Alkaloids

2007
Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Apoptosis; Cell Fractionation; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Docetaxel; Drug Evaluation, Preclinical; ErbB Receptors; Gefitinib; Humans; Male; Neoplasm Invasiveness; Phosphorylation; Prostate; Prostatic Neoplasms; Quinazolines; Taxoids; Transcription Factors; Veratrum Alkaloids; Zinc Finger Protein GLI1

2010
Micellar delivery of cyclopamine and gefitinib for treating pancreatic cancer.
    Molecular pharmaceutics, 2012, Aug-06, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gefitinib; Humans; Male; Mice; Mice, Nude; Micelles; Pancreatic Neoplasms; Quinazolines; Veratrum Alkaloids

2012
Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures.
    Neuro-oncology, 2012, Volume: 14, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Comparative Genomic Hybridization; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Flow Cytometry; Fluorescent Antibody Technique; Glioblastoma; Humans; In Situ Hybridization, Fluorescence; Neoplastic Stem Cells; Quinazolines; Veratrum Alkaloids

2012
Cyclopamine increases the radiosensitivity of human pancreatic cancer cells by regulating the DNA repair signal pathway through an epidermal growth factor receptor‑dependent pathway.
    Molecular medicine reports, 2013, Volume: 8, Issue:4

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Repair; ErbB Receptors; Gefitinib; Histones; Humans; Pancreatic Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Quinazolines; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Veratrum Alkaloids

2013
Hedgehog pathway as a potential treatment target in human cholangiocarcinoma.
    Journal of hepato-biliary-pancreatic sciences, 2014, Volume: 21, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Animals; Benzamides; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cells, Cultured; Cholangiocarcinoma; Female; Gene Expression; Gentamicins; Hedgehog Proteins; Heterografts; Humans; Male; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Oncogene Proteins; Patched Receptors; Polymerase Chain Reaction; Quinazolines; Receptors, Cell Surface; RNA, Messenger; Signal Transduction; Trans-Activators; Veratrum Alkaloids; Zinc Finger Protein GLI1

2014
Shh promotes direct interactions between epidermal cells and osteoblast progenitors to shape regenerated zebrafish bone.
    Development (Cambridge, England), 2017, 04-01, Volume: 144, Issue:7

    Topics: Animal Fins; Animals; Basement Membrane; Benzamides; Bone Regeneration; Calcification, Physiologic; Cell Communication; Cell Movement; Cell Proliferation; Epidermal Cells; Green Fluorescent Proteins; Hedgehog Proteins; Osteoblasts; Quinazolines; Regeneration; Signal Transduction; Smoothened Receptor; Stem Cells; Time Factors; Transcription, Genetic; Veratrum Alkaloids; Zebrafish; Zebrafish Proteins

2017