Compounds > quinazolines
Page last updated: 2024-08-21

quinazolines and cp 100356

quinazolines has been researched along with cp 100356 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Dreslin, JA; Grizzuti, K; Gros, P; Kajiji, S1
Callaghan, R; Ferry, DR; Higgins, CF; Taylor, JC1
Higgins, CF; Konings, WN; Margolles, A; Müller, M; van Veen, HW1
Chupka, J; Feng, B; Fenner, KS; Frederick, KS; Kalgutkar, AS; Kempshall, S; Mireles, RJ; Troutman, MD1
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M1
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M; van de Steeg, E1
Fehling, SK; Groseth, A; Hirabayashi, A; Kajikawa, J; Miyamoto, S; Muramoto, Y; Nakano, M; Noda, T; Strecker, T; Takamatsu, Y; Takenaga, T; Urata, S; Zhang, Z1

Other Studies

7 other study(ies) available for quinazolines and cp 100356

ArticleYear
Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.
    Biochemistry, 1994, May-03, Volume: 33, Issue:17

    Topics: Amino Acid Sequence; Animals; Cell Survival; CHO Cells; Clone Cells; Cricetinae; Cyclosporine; Dibenzocycloheptenes; Drug Resistance; Glycoproteins; Isoquinolines; Mice; Phenylalanine; Point Mutation; Quinazolines; Quinolines; Recombinant Proteins; Serine; Transfection; Vinblastine

1994
The equilibrium and kinetic drug binding properties of the mouse P-gp1a and P-gp1b P-glycoproteins are similar.
    British journal of cancer, 1999, Volume: 81, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Drug Resistance, Multiple; Isoquinolines; Kinetics; Mice; Nicardipine; Progesterone; Protein Binding; Protein Isoforms; Quinazolines; Verapamil; Vinblastine

1999
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism.
    The EMBO journal, 2000, Jun-01, Volume: 19, Issue:11

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Bacterial Proteins; Benzimidazoles; Binding Sites; Biological Transport, Active; Calcium Channel Blockers; Catalysis; Cell Membrane; Dimerization; Drug Resistance, Multiple; Isoquinolines; Lactococcus lactis; Liposomes; Models, Molecular; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Photoaffinity Labels; Protein Structure, Tertiary; Quinazolines; Recombinant Fusion Proteins; Vanadates; Vinblastine

2000
N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a "chemical knock-out equivalent" to assess the impact of efflux transporters on oral drug absorption in the rat.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:12

    Topics: Animals; Anti-Allergic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Carrier Proteins; CHO Cells; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estradiol; Hypnotics and Sedatives; Intestinal Absorption; Isoquinolines; Male; Midazolam; Pharmaceutical Preparations; Prazosin; Quinazolines; Rats; Rats, Sprague-Dawley; Sympatholytics; Terfenadine

2009
Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Ketoconazole; Male; Quinazolines; Quinidine; Rats, Wistar; Rhodamine 123; Verapamil

2015
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 40

    Topics: Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colon; Cyclosporins; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Humans; Ileum; In Vitro Techniques; Isoquinolines; Jejunum; Ketoconazole; Male; Middle Aged; Quinazolines; Quinidine; Verapamil

2017
CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor.
    Viruses, 2021, 09-03, Volume: 13, Issue:9

    Topics: Animals; Antiviral Agents; Arenaviridae; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chlorocebus aethiops; Humans; Isoquinolines; Lassa Fever; Lassa virus; Lymphocytic choriomeningitis virus; Quinazolines; Receptors, Virus; Vero Cells; Vesicular Stomatitis; Viral Fusion Protein Inhibitors; Virus Internalization

2021