quinazolines has been researched along with clonidine in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (84.29) | 18.7374 |
| 1990's | 6 (8.57) | 18.2507 |
| 2000's | 4 (5.71) | 29.6817 |
| 2010's | 1 (1.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kellaway, GS | 1 |
| Petrie, JC | 1 |
| Gain, JM; Mahony, JF; Raftos, J; Stewart, JH; Stokes, GS | 1 |
| Charness, ME; Robertson, D; Snyder, SH; U'Prichard, DC | 1 |
| Lam, E; Timmermans, PB; van Zwieten, PA | 2 |
| Commarato, MA; Dugan, DH; Kaplan, HR; Langley, AE; Lattime, EC; Smith, RD; Tessman, DK | 1 |
| Glossmann, H; Hornung, R; Presek, P | 1 |
| Cavero, I; Lefèvre, F; Roach, AG | 2 |
| Timmermans, PB; Van Zwieten, PA | 1 |
| Constantine, JW; McShane, WK; Weeks, RA | 1 |
| Fang, P; Hua, A; Kincaid-Smith, P; Laver, MC; Macdonald, IM | 1 |
| Fernandes, M; Onesti, G | 1 |
| Kontro, J; Kyöstilä, S; Mattila, MJ; Pitkäjärvi, T | 1 |
| Hammond, JJ; Kirkendall, WM; Overturf, ML; Thomas, JC; Zama, A | 1 |
| Kuokkanen, K; Mattila, MJ | 1 |
| Cavero, I; Dennis, T; Lefèvre-Borg, F; Perrot, P; Roach, AG; Scatton, B | 1 |
| Baumann, N; Chermat, R; Lachapelle, F; Simon, P | 1 |
| Cavero, I; Roach, AG | 2 |
| Bateman, FJ; Curtis, JR | 1 |
| Datey, KK | 1 |
| Evans, RG; Hayes, IP; Ludbrook, J | 1 |
| Akimoto, Y; Fujiwara, M; Kurahashi, K; Sono, K | 1 |
| Nagatomo, T; Tsuchihashi, H | 1 |
| Davies, J | 1 |
| Campbell, SF; Danilewicz, JC; Greengrass, CW; Plews, RM | 1 |
| Aono, J; Nagatomo, T; Nakamura, T; Tajiri, A; Tsuchihashi, H | 1 |
| Aono, J; Sakai, K | 1 |
| Agid, Y; Cash, R; Lasbennes, F; Sercombe, R; Seylaz, J | 1 |
| Jurna, I; Sanders, KH | 1 |
| Kimura, T; Satoh, S; Uchida, W | 1 |
| Buller, A; Conforti, A; Dias Souza, J; Gillis, RA; Kellar, KJ; Quest, JA; Spera, AC | 1 |
| Lyon, TF; Randall, WC | 1 |
| Ali, FK; Kwa, HY; Timmermans, PB; van Zwieten, PA | 1 |
| Mitchell, HC; Pettinger, WA | 1 |
| McPherson, GA; Summers, RJ | 1 |
| Shoji, T | 1 |
| Howe, JR; Wang, JY; Yaksh, TL | 1 |
| Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Hilakivi, I; Leppävuori, A | 1 |
| Drayer, JI; Weber, MA | 1 |
| McCarthy, L; McMahon, KK; Schimmel, RJ | 1 |
| Culvenor, AJ; Jarrott, B; Louis, WJ; Summers, RJ | 1 |
| Cardot, A; Dausse, JP; Meyer, P; Miach, PJ | 1 |
| Davey, MJ | 1 |
| Cardo, B; Kempf, E; Velley, L | 1 |
| Cella, SG; Müller, EE; Picotti, GB | 1 |
| Bühler, FR; Hulthén, UL; Kiowski, W; Ritz, R | 1 |
| De Robertis, E; Levi de Stein, M; Wolfman, C | 1 |
| Heilman, RD; Lee, JY; Radzialowski, FM; Walsh, GM | 1 |
| Cotterell, DJ; Munday, KA; Poat, JA | 1 |
| Drayer, JI; Hubbell, FA; Rose, DE; Weber, MA | 1 |
| Arnold, H; Hörmann, E; Schaffler, K | 1 |
| Díaz Novás, J; Gamio Capestany, F; García-Barreto, D; González-Gómez, A; Rodríguez de la Vega, A | 1 |
| Bhatnagar, RK; Cannon, JG; Chatterjee, TK; Long, JP | 1 |
| Kaplan, HR; Smith, RD; Tessman, DK | 1 |
| Bentley, GA; McLennan, PL | 1 |
| Andréjak, M; Coevoet, B; Comoy, E; De Fremont, JF; Fievet, P; Fournier, A; Makdassi, R | 1 |
| Chen, SY; Chern, JW; Tao, PL; Tseng, CJ; Yen, MH | 1 |
| Chiba, S; Nakane, T; Ren, LM | 1 |
| Arai, M; Fujiwara, H; Fujiwara, T; Kariya, T; Koshiji, M; Minatoguchi, S; Ohno, T; Uno, Y; Yamashita, K | 1 |
| Asakura, Y; Ebihara, Y; Hasegawa, H; Nakamura, Y; Shinmura, K; Suganuma, Y; Tani, M | 1 |
| Endo, T; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Satoh, Y; Suzuguchi, T | 1 |
| Endo, T; Hamaue, N; Hirafuji, M; Kato, K; Minami, M; Ogawa, T; Parvez, H | 1 |
| Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB | 1 |
| Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T | 1 |
| Angeli, P; Buccioni, M; Giardinà, D; Gulini, U; Marucci, G; Melchiorre, C; Sagratini, G; Testa, R | 1 |
| Fälting, JM; Holmström, TE; Mattsson, CL; Nedergaard, J; Wang, Y | 1 |
3 review(s) available for quinazolines and clonidine
| Article | Year |
|---|---|
Recent acquisitions in antihypertensive therapy: clonidine, minoxidil and prazosin.
Topics: Animals; Clonidine; Dogs; Hemodynamics; Humans; Hypertension; Minoxidil; Prazosin; Pyrimidines; Quinazolines; Rats | 1978 |
Central and peripheral blockade of the sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Indoramin; Labetalol; Methyldopa; Prazosin; Quinazolines; Reserpine; Sympathetic Nervous System; Sympatholytics | 1984 |
The pharmacology of prazosin, a novel antihypertensive agent.
Topics: Adrenal Glands; Animals; Antihypertensive Agents; Brain; Clonidine; Dogs; Heart Rate; Humans; Hypotension, Orthostatic; Norepinephrine; Phentolamine; Prazosin; Quinazolines; Rabbits; Rats; Receptors, Adrenergic, alpha; Renin; Substrate Specificity | 1980 |
7 trial(s) available for quinazolines and clonidine
| Article | Year |
|---|---|
Changing concepts in the management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Animals; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Diazoxide; Diet, Sodium-Restricted; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Methyldopa; Piperazines; Quinazolines; Reserpine; Vasodilator Agents | 1975 |
Antihypertensive drug combinations: prazosin, hydrochlorothiazide and clonidine.
Topics: Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Drug Combinations; Drug Evaluation; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines; Time Factors | 1977 |
Prazosin and clonidine for moderately severe hypertension.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Polythiazide; Prazosin; Quinazolines | 1978 |
Antihypertensive effect of prazosin in combination with methyldopa, clonidine, or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Combinations; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Placebos; Prazosin; Propranolol; Quinazolines | 1979 |
Use of prazosin in management of hypertension in patients with chronic renal failure and in renal transplant recipients.
Topics: Adult; Aged; Antihypertensive Agents; Chlorothiazide; Clinical Trials as Topic; Clonidine; Drug Evaluation; Drug Therapy, Combination; Edetic Acid; Female; Furosemide; Humans; Hypertension, Renal; Hypotension, Orthostatic; Kidney Failure, Chronic; Kidney Transplantation; Male; Methyldopa; Middle Aged; Piperazines; Propranolol; Quinazolines | 1975 |
Comparative antihypertensive and endocrinologic effects of clonidine and prazosin in patients with essential hypertension.
Topics: Adult; Blood Pressure; Catecholamines; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Prazosin; Quinazolines; Random Allocation; Renin-Angiotensin System; Time Factors | 1984 |
[Changes in vigilance after acute and repeated administration of the antihypertensive agents clonidine and prazosin].
Topics: Adult; Attention; Clonidine; Female; Humans; Hypertension; Long-Term Care; Male; Prazosin; Quinazolines; Saccades | 1983 |
60 other study(ies) available for quinazolines and clonidine
| Article | Year |
|---|---|
Adverse drug reactions during treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Drug Interactions; Humans; Hydralazine; Male; Methyldopa; Middle Aged; Piperazines; Practolol; Quinazolines | 1976 |
Diseases of the cardiovascular system Hypertension--II.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Debrisoquin; Diazoxide; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Methyldopa; Phytotherapy; Piperazines; Plants, Medicinal; Quinazolines; Rauwolfia | 1976 |
Long-term use of prazosin in combination or alone for treating hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines | 1977 |
Prazosin: differential affinities for two populations of alpha-noradrenergic receptor binding sites.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dihydroergotoxine; In Vitro Techniques; Male; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
The interaction between prazosin and clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Heart Rate; Prazosin; Quinazolines; Rats | 1978 |
Prazosin and phentolamine: comparative cardiovascular and autonomic profiles.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Female; Guinea Pigs; Heart; In Vitro Techniques; Leg; Male; Phenoxybenzamine; Phentolamine; Prazosin; Quinazolines; Rats; Sympathetic Nervous System; Vasodilator Agents | 1978 |
Alpha adrenoceptors in rat brain: direct identification with prazosin.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Clonidine; Hydrogen-Ion Concentration; In Vitro Techniques; Membranes; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sulfhydryl Reagents; Time Factors | 1979 |
Differential effects of prazosin on the pre- and postsynaptic alpha-adrenoceptors in the rat and dog [proceedings].
Topics: Animals; Clonidine; Dogs; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Species Specificity | 1977 |
Influence of structural changes in the imidazolidine ring of clonidine on hypotensive activity.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Evaluation, Preclinical; Heart Rate; Hypotension; Imidazoles; Male; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Thiazoles | 1978 |
Prazosin and presynaptic alpha-receptors in the cardioaccelerator nerve of the dog.
Topics: Animals; Clonidine; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Male; Myocardial Contraction; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vagotomy; Yohimbine | 1978 |
The interaction between prazosin and clonidine at alpha-adrenoceptors in rats and cats.
Topics: Anesthesia; Animals; Blood Pressure; Cats; Clonidine; Drug Interactions; Female; Hemodynamics; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Spinal Cord | 1979 |
Effects of prazosin and phentolamine on cardiac presynaptic alpha-adrenoceptors in the cat, dog and rat.
Topics: Animals; Cats; Clonidine; Depression, Chemical; Dogs; Electric Stimulation; Female; Heart Rate; Imidazoles; Male; Phentolamine; Phenylephrine; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1978 |
Effects of clonidine, prazosin and phentolamine on heart rate and coronary sinus catecholamine concentration during cardioaccelerator nerve stimulation in spinal dogs.
Topics: Animals; Catecholamines; Clonidine; Coronary Vessels; Dogs; Drug Interactions; Electric Stimulation; Female; Heart; Heart Rate; Male; Phentolamine; Prazosin; Quinazolines; Spinal Cord; Time Factors | 1979 |
Anticonvulsant effect of yohimbine in quaking mice: antagonism by clonidine and prazosine.
Topics: Animals; Anticonvulsants; Clonidine; Male; Mice; Mice, Quaking; Phentolamine; Prazosin; Quinazolines; Seizures; Yohimbine | 1979 |
The effects of prazosin on the clonidine induced hypotension and bradycardia in rats and sedation in chicks [proceedings].
Topics: Animals; Blood Pressure; Chickens; Clonidine; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Prazosin; Quinazolines; Rats | 1978 |
V World Congress of Cardiology Souvenir Oration. Recent trends in the management of hypertension.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hypertension; Male; Piperazines; Quinazolines; Relaxation Therapy; Yoga | 1975 |
Effects of alpha-adrenoceptor antagonists and clonidine on the haemodynamic response to acute hypovolaemia in conscious rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hemorrhage; Injections, Intravenous; Pharmaceutical Vehicles; Plasma Volume; Quinazolines; Rabbits; Yohimbine | 1992 |
Effects of specific alpha-adrenoceptive agents on extraneuronal uptake (uptake2) of isoproterenol in perfused rat heart.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Guanabenz; Isoproterenol; Male; Methoxamine; Myocardium; Neurons; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Sulfonamides; Tropolone | 1989 |
Alpha-blocking potencies of antihypertensive agents (prazosin, terazosin, bunazosin, SGB-1534 and ketanserin) having with quinazoline or quinazolinedione as assessed by radioligand binding assay methods in rat brain.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Brain; Cell Membrane; Clonidine; Dihydroalprenolol; Ketanserin; Male; Prazosin; Quinazolines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1989 |
Effects of tizanidine, eperisone and afloqualone on feline dorsal horn neuronal responses to peripheral cutaneous noxious and innocuous stimuli.
Topics: Air; Analgesics; Animals; Cats; Clonidine; Hot Temperature; Injections, Intravenous; Iontophoresis; Muscle Relaxants, Central; Neurons; Peripheral Nerves; Propiophenones; Quinazolines; Skin; Spinal Cord | 1989 |
2,4-Diamino-6,7-dimethoxyquinazolines. 4. 2-[4-(substituted oxyethoxy) piperidino] derivatives as alpha 1-adrenoceptor antagonists and antihypertensive agents.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Half-Life; Hydrogen-Ion Concentration; Prazosin; Quinazolines; Rabbits | 1988 |
Effect of 3-[2-[4-(o-methoxyphenyl)-1-piperazinyl]ethyl]-2,4(1H,3H)- quinazolinedione monophydrochloride (SGB-1534), an antihypertensive agent, on 3H-prazosin and 3H-p-aminoclonidine binding to alpha 1- and alpha 2-adrenoceptors in dog brain and aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Brain; Clonidine; Dogs; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Prazosin; Quinazolines; Receptors, Adrenergic, alpha | 1988 |
Investigations into the mechanism of the antihypertensive effect of SGB-1534, a novel alpha 1-adrenoceptor antagonist, in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1988 |
Adrenergic receptors on cerebral microvessels in control and parkinsonian subjects.
Topics: Aged; Alprenolol; Capillaries; Cerebrovascular Circulation; Clonidine; Dihydroalprenolol; Humans; Kinetics; Parkinson Disease; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reference Values | 1985 |
Effects of urapidil, clonidine, prazosin and propranolol on autonomic nerve activity, blood pressure and heart rate in anaesthetized rats and cats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Cats; Clonidine; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Neurons; Piperazines; Prazosin; Propranolol; Quinazolines; Rats; Rats, Inbred Strains; Species Specificity; Splanchnic Nerves; Sympathetic Nervous System; Vagus Nerve | 1985 |
Presence of presynaptic inhibitory alpha 1-adrenoceptors in the cardiac sympathetic nerves of the dog: effects of prazosin and yohimbine on sympathetic neurotransmission to the heart.
Topics: Animals; Clonidine; Dogs; Female; Heart Rate; Male; Methoxamine; Myocardium; Norepinephrine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Stellate Ganglion; Sympathetic Nervous System; Synaptic Transmission; Tachycardia; Yohimbine | 1984 |
Comparative effects of urapidil, prazosin, and clonidine on ligand binding to central nervous system receptors, arterial pressure, and heart rate in experimental animals.
Topics: Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Piperazines; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Muscarinic | 1984 |
Multiple central WB-4101 binding sites and the selectivity of prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Brain; Cattle; Clonidine; Dioxanes; Dioxins; In Vitro Techniques; Kinetics; Membranes; Norepinephrine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha | 1980 |
Prazosin and its analogues UK-18,596 and UK-33,274: a comparative study on cardiovascular effects and alpha-adrenoceptor blocking activities.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Clonidine; Doxazosin; Heart Rate; Hemodynamics; Hexobarbital; Injections, Intraventricular; Male; Phenylephrine; Prazosin; Quinazolines; Rats | 1980 |
Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Body Weight; Clonidine; Diastole; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Minoxidil; Norepinephrine; Posture; Prazosin; Propranolol; Quinazolines; Renin; Systole | 1981 |
[3H]prazosin and [3H]clonidine binding to alpha-adrenoceptors in membranes prepared from regions of rat kidney.
Topics: Animals; Binding Sites; Clonidine; In Vitro Techniques; Kidney; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Species Specificity; Tritium | 1981 |
Comparison of pre- and postsynaptic alpha-adrenoceptor blocking effects of E-643 in the isolated vas deferens of the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1981 |
Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Hot Temperature; Hydroxydopamines; Injections, Spinal; Male; Methoxamine; Norepinephrine; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spinal Cord; Yohimbine | 1983 |
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction | 1984 |
Effects of methoxamine, and alpha-1 adrenoceptor agonist, and prazosin, an alpha-1 antagonist, on the stages of the sleep-waking cycle in the cat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cats; Clonidine; Dose-Response Relationship, Drug; Male; Methoxamine; Prazosin; Quinazolines; Sleep; Sleep Stages; Sleep, REM; Wakefulness | 1984 |
Alpha 1-adrenergic stimulation of hamster brown adipocyte respiration.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue, Brown; Animals; Clonidine; Cricetinae; Isoproterenol; Kinetics; Male; Mesocricetus; Methoxamine; Norepinephrine; Oxygen Consumption; Phenylephrine; Prazosin; Propranolol; Quinazolines; Receptors, Adrenergic, alpha | 1983 |
Characterization of alpha-adrenoceptors in rat and guinea pig tissues using radiolabeled agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Clonidine; Dioxanes; Dioxins; Guinea Pigs; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
3H-Prazosin binds specifically to 'alpha 1'-adrenoceptors in rat brain.
Topics: Animals; Brain; Clonidine; In Vitro Techniques; Kinetics; Male; Prazosin; Quinazolines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha | 1980 |
Aspects of the pharmacology of prazosin.
Topics: Animals; Cats; Clonidine; Femoral Artery; Femoral Vein; In Vitro Techniques; Mesenteric Arteries; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Pulmonary Artery; Quinazolines; Rabbits; Receptors, Adrenergic, alpha; Vasodilation; Yohimbine | 1980 |
Locomotor activity of rats after stimulation of the nucleus locus coeruleus region or after lesion of the dorsal noradrenergic bundle: effects of clonidine, prazosin and yohimbine.
Topics: Animals; Brain Stem; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Exploratory Behavior; Hippocampus; Hydroxydopamines; Locus Coeruleus; Male; Motor Activity; Neural Pathways; Norepinephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Yohimbine | 1982 |
alpha2-Adrenergic stimulation enhances growth hormone secretion in the dog: a presynaptic mechanism?
Topics: Animals; Clonidine; Dogs; Female; Growth Hormone; Kinetics; Male; Prazosin; Quinazolines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Reserpine; Synapses; Yohimbine | 1983 |
Alpha 2 adrenoceptor-mediated vasoconstriction of arteries.
Topics: Adult; Brachial Artery; Clonidine; Drug Interactions; Female; Hemodynamics; Humans; Infusions, Intra-Arterial; Male; Phentolamine; Prazosin; Quinazolines; Receptors, Adrenergic, alpha; Vasoconstriction | 1983 |
Time course of changes in [3H]prazosin binding after catecholaminergic denervation by 6-hydroxydopamine in rat cerebral cortex. Inhibitory effects of ascorbic acid on the alpha 1-adrenoceptor.
Topics: Animals; Ascorbic Acid; Brain; Catecholamines; Clonidine; Female; Hydroxydopamines; Kinetics; Male; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathectomy, Chemical; Time Factors | 1983 |
Differential blocking effects of prazosin and yohimbine on vasopressor responses to sympathetic nerve stimulation and intravenous norepinephrine in the pithed rat.
Topics: Animals; Blood Pressure; Clonidine; Electric Stimulation; Male; Norepinephrine; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction; Yohimbine | 1984 |
The binding of [3H]prazosin and [3H]clonidine to rat jejunal epithelial cell membranes.
Topics: Animals; Binding, Competitive; Cell Membrane; Clonidine; Epithelium; Jejunum; Kinetics; Male; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1984 |
Clonidine and prazosin in the treatment of hypertensive outpatients--a preliminary study.
Topics: Adult; Ambulatory Care; Blood Pressure; Clonidine; Drug Therapy, Combination; Drug Tolerance; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines; Time Factors | 1983 |
Interaction of dihydroxy-2-aminotetralin derivatives at sites labelled with [3H]clonidine, [3H]prazosin and [3H]spiperone in rat brain membranes.
Topics: Animals; Binding Sites; Brain; Butyrophenones; Cell Membrane; Cerebral Cortex; Clonidine; Drug Interactions; Male; Naphthalenes; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Spiperone; Tetrahydronaphthalenes | 1984 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin | 1981 |
Effects of prazosin and piperoxan on central cardiovascular actions of St 91 in cats.
Topics: Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Female; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Injections, Intravenous; Male; Piperidines; Piperoxan; Prazosin; Quinazolines; Vertebral Artery | 1982 |
Lack of antagonism in the antihypertensive effects of clonidine and prazosin in man.
Topics: Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines | 1981 |
Antihypertensive effects of AT-112, a newly synthesized quinazoline derivative, in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Clonidine; Endothelium, Vascular; Female; Hypertension; Male; Phenylephrine; Prazosin; Quinazolines; Rats; Rats, Inbred SHR; Serotonin; Vasodilation | 1995 |
Characteristics of the responses of isolated and perfused canine splenic arteries to vasoactive substances and to periarterially electrical stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Electric Stimulation; Female; Imidazoles; In Vitro Techniques; Male; Norepinephrine; Quinazolines; Splenic Artery; Vasoconstriction; Vasoconstrictor Agents | 1994 |
Infarct size-reducing effect of ischemic preconditioning is related to alpha1b-adrenoceptors but not to alpha1a-adrenoceptors in rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Ischemic Preconditioning, Myocardial; Male; Phenoxybenzamine; Piperazines; Quinazolines; Rabbits; Receptors, Adrenergic, alpha-1 | 1997 |
Effects of alpha 1-adrenoreceptor subtype blockade on ischemia-reperfusion injury.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Dioxanes; Energy Metabolism; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Quinazolines; Rats; Rats, Sprague-Dawley | 1997 |
[Signal transduction of serotonin release from enterochromaffin cells in mouse ileal crypts].
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Enterochromaffin Cells; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Norepinephrine; Phosphodiesterase Inhibitors; Prazosin; Pyrrolidinones; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rolipram; Serotonin; Signal Transduction; Yohimbine | 1998 |
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Ileum; In Vitro Techniques; Male; Methoxamine; Mice; Mice, Inbred ICR; Norepinephrine; Pertussis Toxin; Phenylephrine; Quinazolines; Quinoxalines; Receptors, Adrenergic, alpha-2; Serotonin; Virulence Factors, Bordetella; Yohimbine | 2001 |
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: functional evaluation in rat and rabbit tissues.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methoxamine; Molecular Structure; Muscle Contraction; Norepinephrine; Quinazolines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens; Vasoconstriction | 2005 |
In brown adipocytes, adrenergically induced β₁-/β₃-(Gs)-, α₂-(Gi)- and α₁-(Gq)-signalling to Erk1/2 activation is not mediated via EGF receptor transactivation.
Topics: Adipocytes, Brown; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Antagonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Animals; Clonidine; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Imidazoles; Male; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Norepinephrine; Phosphorylation; Quinazolines; Receptors, Adrenergic; Tyrphostins | 2013 |