quinazolines and cl 387785

Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Enzyme Inhibitors; ErbB Receptors; Female; Mice; Mice, Nude; Models, Molecular; Neoplasm Transplantation; Neoplasms, Experimental; Phosphorylation; Quinazolines; Tumor Cells, Cultured

Topics: Animals; Cell Division; Cell Survival; Disease Models, Animal; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation, Enzymologic; Kidney Tubules, Collecting; Mice; Mice, Mutant Strains; Nephrons; Organ Culture Techniques; Phosphorylation; Polycystic Kidney Diseases; Protein-Tyrosine Kinases; Quinazolines

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mice; Mice, Inbred BALB C; Polycystic Kidney Diseases; Protein-Tyrosine Kinases; Quinazolines

Topics: Adenomatous Polyposis Coli; Aminoquinolines; Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Therapy, Combination; Enzyme Inhibitors; ErbB Receptors; Mice; Mice, Mutant Strains; Organic Chemicals; Quinazolines; Sulindac

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Isoquinolines; Kidney; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenotype; Polycystic Kidney Diseases; Quinazolines; Signal Transduction; Sulfonamides

Topics: Animals; Disease Models, Animal; ErbB Receptors; Gastric Lavage; Injections, Intraperitoneal; Male; Polycystic Kidney Diseases; Quinazolines; Rats; Rats, Sprague-Dawley

Topics: Aminoquinolines; Aniline Compounds; Animals; Cyclic AMP; Disease Models, Animal; ErbB Receptors; Female; Injections, Intraperitoneal; Intubation, Gastrointestinal; Kidney; Male; Organic Chemicals; Polycystic Kidney, Autosomal Recessive; Quinazolines; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Vasopressin; Severity of Illness Index

Topics: Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Mutation; Pharmacogenetics; Protein-Tyrosine Kinases; Quinazolines; Randomized Controlled Trials as Topic

Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Growth Processes; Cell Line, Tumor; DNA-Binding Proteins; Drug Interactions; ErbB Receptors; Gefitinib; Genes, erbB-1; Interleukin-3; Mice; Milk Proteins; Mutation; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; STAT5 Transcription Factor; Trans-Activators

Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Exons; Gefitinib; Genetic Therapy; Humans; Mice; Mice, Nude; Mutation; Neoplasms, Experimental; NIH 3T3 Cells; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; STAT3 Transcription Factor; Transfection; Tumor Stem Cell Assay

Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; ErbB Receptors; Eukaryotic Initiation Factor-4E; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunoblotting; Immunoprecipitation; Models, Biological; Phosphoproteins; Phosphorylation; Protein Kinases; Quinazolines; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Thymidine; TOR Serine-Threonine Kinases

Topics: Alleles; Animals; Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Amplification; Humans; Lung Neoplasms; Mice; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-3; RNA Interference; Transfection; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclin D; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Flavonoids; Gefitinib; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mutant Proteins; Mutation, Missense; Oligonucleotide Array Sequence Analysis; Piperidines; Quinazolines; Signal Transduction; Transcription, Genetic; Transfection

Topics: Apoptosis; Blotting, Western; Cell Proliferation; ErbB Receptors; Female; Humans; Mitogen-Activated Protein Kinase Kinases; Ovarian Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; U937 Cells

Topics: Cell Line, Tumor; Cyclin-Dependent Kinase 4; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Quinazolines; Structure-Activity Relationship

Topics: Blotting, Western; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Humans; Microfluidics; Microscopy, Confocal; Phosphorylation; Quinazolines; Receptor, IGF Type 1; Receptors, Opioid, delta; Transcriptional Activation; Tyrphostins

Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinoma, Acinar Cell; Cell Line, Tumor; Cell Movement; Cell Shape; Deoxycytidine; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gemcitabine; Gene Expression Profiling; Humans; Lung Neoplasms; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Quinazolines; Sequence Deletion

Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Image Processing, Computer-Assisted; Lung Neoplasms; Mice; Mice, Inbred BALB C; Multimodal Imaging; Positron-Emission Tomography; Protein Kinase Inhibitors; Quinazolines; Radiopharmaceuticals; Sulfonamides; Tomography, X-Ray Computed

Topics: Actins; Apoptosis; Blotting, Western; Cell Line; Cell Nucleus; Cell Proliferation; Cyclooxygenase 2; ErbB Receptors; Flow Cytometry; Heterocyclic Compounds, 4 or More Rings; Humans; Immunoprecipitation; Molecular Motor Proteins; Myosin Heavy Chains; Myosin Type II; Protein Binding; Quinazolines; Real-Time Polymerase Chain Reaction; RNA Interference

Topics: Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Everolimus; Extracellular Signal-Regulated MAP Kinases; Fluorouracil; Gene Amplification; Humans; Paclitaxel; Quinazolines; Receptor, ErbB-2; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stomach Neoplasms; TOR Serine-Threonine Kinases; Trastuzumab

Topics: Acrylamides; Afatinib; Aminopyridines; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Crizotinib; Drug Resistance, Neoplasm; Drugs, Investigational; ErbB Receptors; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Lung Neoplasms; Molecular Targeted Therapy; Mutation; Neoplasms; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Pyrimidines; Pyrrolidinones; Quinazolines; Quinolines; Signal Transduction; Up-Regulation; Vascular Endothelial Growth Factor Receptor-2

Topics: Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Quinazolines