Page last updated: 2024-08-21

quinazolines and changrolin

quinazolines has been researched along with changrolin in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199024 (66.67)18.7374
1990's9 (25.00)18.2507
2000's1 (2.78)29.6817
2010's2 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ding, GS; Hu, GJ; Li, LQ; Qu, ZX; Wang, ZM; Yang, XY; Zeng, YL1
Chen, WZ; Ding, GS; Dong, YL1
Fang, DC; Wu, YJ2
Chen, YH; Cheng, JH; Dai, DZ; Huang, J; Huang, WL; Liu, J; Peng, SX; Qiu, YT; Rong, P1
Chen, KJ; Chen, YQ1
Kuang, Y; Liu, TP1
Pan, H; Shen, WQ; Xu, B; Yu, ZM1
Chen, WZ; Gu, PK; Jin, ZJ; Liu, QY; Wei, PJ1
Chen, HZ; Chen, WZ; Gong, ZX; Guo, Q; Jin, PY; Pen, BZ; Shen, JY; Yang, XY; Yang, YZ1
Chen, WZ; Ding, GS; Li, HQ1
Chen, WZ; Ding, RQ; Dong, YL; Zhang, X1
Chen, JR; Chen, WZ; Guo, Q; Jin, PY; Yang, XY; Yang, YZ1
Chen, WZ; Chen, YM; Li, CF; Qi, HM; Shen, LY; Wang, CG; Xu, JM; Yin, XL1
Bao, YX; Bian, YT; Zheng, DS1
Gu, PK; Jin, ZJ; Yu, FS; Yu, Y1
Cai, NS; Chen, WZ; Wang, CG; Yang, XY; Zhu, JR1
Ding, GS; Wang, CG; Wang, ZM; Zhang, YF1
Li, ZY1
Chen, YL; Gu, PK; Jin, ZJ; Liu, XJ; Shang, M; Wang, BY1
Gu, SL; Shen, YT; Wu, PM; Xu, NS1
Chen, WZ; Ding, GS; Li, RS; Zhang, YF1
Chen, WZ; Ding, GS; Dong, YL; Gu, CG1
Chen, EH; Tu, ZH; Wu, WW; Yang, HH1
Chen, WZ; Dong, YL; Shen, YT; Wan, FT; Wu, PM1
Gu, HM; Qu, ZX; Xu, GY; Yi, QC; Zeng, YL1
Barcelon-Yang, C; Brown, BS; Matier, WL; Reynolds, RD; Stout, DM1
Cao, CY; Qu, ZX; Zhuang, YH1
Ji, RY; Shen, J; Shu, Y; Sun, CJ; Wang, PP; Yang, XZ; Zhang, XY1
Carmeliet, E; Xu, YQ1
Habuchi, Y; Lu, LL; Morikawa, J; Tanaka, H1
Feng, JL; Gu, YB; Liu, CX; Sun, JL; Wei, GL; Xiao, SH1
Lü, LL1
Li, S; Liu, G; Lu, Y; Wang, Y; Yang, D; Yu, C1
Chen, WH; Wang, WY; Wang, YP; Yang, D; Zhang, J2

Reviews

2 review(s) available for quinazolines and changrolin

ArticleYear
[Computer simulation in studies on mechanisms of action of antiarrhythmic agents].
    Sheng li ke xue jin zhan [Progress in physiology], 1992, Volume: 23, Issue:1

    Topics: Anti-Arrhythmia Agents; Computer Simulation; Lidocaine; Quinazolines

1992
[Advances in the research on the treatment of arrhythmia with traditional Chinese medicine].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991, Volume: 11, Issue:7

    Topics: Acupuncture Therapy; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drugs, Chinese Herbal; Humans; Quinazolines

1991

Other Studies

34 other study(ies) available for quinazolines and changrolin

ArticleYear
Studies on a new antiarrhythmic drug changrolin-4-(3',5'-bis [(N-pyrrolidinyl) methyl]-4'-hydroxyanilino)-quinazoline.
    Scientia Sinica, 1979, Volume: 22, Issue:10

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electrocardiography; Heart Rate; Humans; Quinazolines; Rabbits; Rats

1979
[Cardiovascular effect of a new antiarrhythmic drug--changrolin (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1979, Volume: 14, Issue:12

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output; Cardiovascular System; Dogs; Electrocardiography; Pyrrolidines; Quinazolines; Tachycardia; Vascular Resistance

1979
[Modelling and kinetic analysis on changrolin block of cardiac Na+ channels].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:4

    Topics: Anti-Arrhythmia Agents; Computer Simulation; Membrane Potentials; Myocardium; Quinazolines; Sodium Channels

1991
Anti-arrhythmic activities of six indole derivatives of changrolin.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Guinea Pigs; Indoles; Mexiletine; Myocardial Reperfusion Injury; Quinazolines; Tachycardia; Ventricular Fibrillation

1991
Rate-dependent depression of maximal rate of depolarization in guinea pig papillary muscle action potentials by changrolin.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Female; Guinea Pigs; In Vitro Techniques; Male; Mexiletine; Papillary Muscles; Piperidines; Quinazolines; Quinidine

1990
[Frequency- and voltage-dependent effects of changrolin on maximal upstroke velocity of action potentials in guinea pig papillary muscles].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:4

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electronic Data Processing; Female; Guinea Pigs; In Vitro Techniques; Male; Microelectrodes; Papillary Muscles; Quinazolines

1990
[Electrophysiological effects of changrolin on single ventricular myocytes isolated from adult guinea pig].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Electrophysiology; Female; Male; Membrane Potentials; Mice; Myocardium; Quinazolines

1989
[Cytotoxic effects of changrolin, lidocaine and amiodarone on ultrastructure of cultured rat beating cardiac myocytes].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Lidocaine; Myocardium; Quinazolines; Rats

1989
[Antagonistic effects of changrolin on the contraction of rabbit aortic rings evoked by norepinephrine, potassium and calcium].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1985, Volume: 6, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Calcium Chloride; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Quinazolines; Rabbits

1985
[Autoradiographic studies on the distribution of [14C]changrolin in mice].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Autoradiography; Male; Mice; Quinazolines; Tissue Distribution

1986
[Cytotoxic effects of changrolin, lidocaine and amiodarone on cultured beating rat heart cells].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Aspartate Aminotransferases; Cells, Cultured; Lidocaine; Myocardium; Quinazolines; Rats; Rats, Inbred Strains

1987
[Plasma drug concentration and cardiac function in arrhythmic patients during continuous drip of changrolin].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiography, Impedance; Female; Hemodynamics; Humans; Male; Middle Aged; Quinazolines

1987
[Further exploration on the effect of some Chinese anti-arrhythmics on cardiac conductive system].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1987, Volume: 7, Issue:9

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Blood Pressure; Dogs; Drugs, Chinese Herbal; Electrocardiography; Female; Heart Conduction System; Male; Panax; Plants, Medicinal; Quinazolines

1987
[Electrophysiologic effects of changrolin on the cardiac conduction system in anesthetized rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Bundle of His; Electric Stimulation; Electrophysiology; Female; Heart Conduction System; Male; Procainamide; Quinazolines; Rabbits

1987
[Clinical pharmacokinetics of the anti-arrhythmic agent changrolin].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:7

    Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Kinetics; Male; Middle Aged; Quinazolines

1985
[Comparison of antiarrhythmic effects of intravenous injections of changrolin and BL-4712A(author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Indoles; Injections, Intravenous; Isoindoles; Male; Quinazolines; Rabbits; Rats

1982
[Effect of anti-arrhythmic drug changrolin on fast and slow response potentials of myocardial cell of rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Female; Heart; In Vitro Techniques; Male; Quinazolines; Rats; Refractory Period, Electrophysiological

1982
[Effects of changrolin on electrophysiological properties of canine Purkinje fibers].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1983, Volume: 4, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Heart Conduction System; In Vitro Techniques; Procaine; Purkinje Fibers; Quinazolines

1983
[Effects of intravenous infusion of changrolin on cardiac function of patients with arrhythmia].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1983, Volume: 4, Issue:4

    Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Hemodynamics; Humans; Male; Middle Aged; Quinazolines

1983
[Effects of changrolin on contractility and excitability of isolated cat papillary muscle].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Chloride; Cats; Female; Male; Myocardial Contraction; Niacinamide; Papillary Muscles; Quinazolines; Verapamil

1984
[Anti-arrhythmic effect of changrolin combined with nicotinamide in experimental arrhythmia].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Combinations; Female; Guinea Pigs; Lethal Dose 50; Male; Mice; Niacinamide; Quinazolines; Rabbits; Rats

1984
[Effects of changrolin and pyracrine phosphate on ATPase of rabbit heart sarcolemma].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:3

    Topics: Adenosine Triphosphatases; Aminoacridines; Animals; Anti-Arrhythmia Agents; Calcium-Transporting ATPases; In Vitro Techniques; Myocardium; Quinazolines; Rabbits; Sarcolemma; Sodium-Potassium-Exchanging ATPase

1982
[Effects of antiarrhythmic drug changrolin on myocardial contractility in anesthetized dogs (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:1

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Dogs; Myocardial Contraction; Quinazolines

1981
[Physiological disposition of changrolin (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1981, Volume: 2, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Half-Life; Kinetics; Quinazolines; Rabbits; Rats; Tissue Distribution

1981
Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 1. Heteroarylamine derivatives.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Guinea Pigs; Ileum; Male; Muscle Contraction; Parasympatholytics; Quinazolines

1983
[The effects of infusion rate of Changrolin on drug concentration in blood and ECG (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1980, Volume: 15, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Electrocardiography; Heart Rate; Infusions, Parenteral; Pyrrolidines; Quinazolines

1980
[Studies on drugs for coronary diseases. II. Synthesis of compounds related to changrolin as potential antiarrhythmic drugs (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1981, Volume: 16, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Quinazolines; Rats; Structure-Activity Relationship

1981
Electrophysiological effects of changrolin, a new antiarrhythmic drug, on isolated cardiac preparations.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 253, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Kinetics; Purkinje Fibers; Quinazolines; Sheep

1981
Electrophysiological effects of changrolin, an anti-arrhythmic agent derived from Dichroa febrifuga, on guinea-pig and rabbit heart cells.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:5

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Function; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Ion Transport; Patch-Clamp Techniques; Potassium; Quinazolines; Rabbits; Species Specificity; Ventricular Function

1995
Pharmacokinetic-pharmacodynamic analysis of changrolin in dogs with arrhythmia.
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electrocardiography; Male; Quinazolines

1996
Effects of changrolin on potassium currents in guinea pig and rabbit single heart cells.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:11

    Topics: Animals; Anti-Arrhythmia Agents; Cell Separation; Guinea Pigs; Myocardium; Patch-Clamp Techniques; Potassium Channels; Quinazolines; Rabbits

1999
Liquid chromatography/tandem mass spectrometry for the determination of changrolin in rat plasma: application to a bioavailability study.
    Journal of pharmaceutical and biomedical analysis, 2009, Sep-08, Volume: 50, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Biological Availability; Calibration; Chromatography, Liquid; Quinazolines; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2009
State-dependent blockade of human ether-a-go-go-related gene (hERG) K(+) channels by changrolin in stably transfected HEK293 cells.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:8

    Topics: Anti-Arrhythmia Agents; Cell Line; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Kidney; Patch-Clamp Techniques; Quinazolines; Transfection

2010
Cellular electrophysiological effects of changrolin in isolated rat cardiac myocytes.
    European journal of pharmacology, 2010, Nov-25, Volume: 647, Issue:1-3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channels; Drugs, Chinese Herbal; Electrophysiological Phenomena; Heart Ventricles; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Quinazolines; Rats; Rats, Sprague-Dawley; Sodium Channels

2010