quinazolines has been researched along with cb 3705 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cesar, D; Coll, RJ; Hynes, JB; Shane, B | 1 |
| Balmanno, K; Calvert, AH; Hughes, LR; Jackman, AL; Taylor, GA | 1 |
| Calvert, AH; Dady, PJ; Grzelakowska-Sztabert, B; Harrap, KR; Jones, TR; Paine, RM; Taylor, GA | 1 |
| Cook, RJ | 1 |
| Corona, P; Loriga, M; Paglietti, G; Vitale, G | 1 |
| DeRose, EF; Gabel, SA; Howell, EE; Lebetkin, MS; Levy, LA; Li, D; London, RE; Wall, MJ | 1 |
| Krupenko, SA; Vlasov, AP; Wagner, C | 1 |
| Caperelli, CA; Dahms, TE; Giroux, EL; Sainz, G; Smith, JL | 1 |
8 other study(ies) available for quinazolines and cb 3705
| Article | Year |
|---|---|
In vitro metabolism of 5,8-dideazafolates and 5,8-dideazaisofolates by mammalian folylpoly-gamma-glutamate synthetase.
Topics: Aminopterin; Animals; Folic Acid Antagonists; Kinetics; Liver; Peptide Synthases; Pteroylpolyglutamic Acids; Quinazolines; Structure-Activity Relationship; Substrate Specificity | 1991 |
Estimation of the in vitro and in vivo inhibitory effects of antifolates upon thymidylate synthase (TS) in whole cells.
Topics: Animals; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Mice; Mice, Inbred DBA; Quinazolines; Structure-Activity Relationship; Thymidylate Synthase; Time Factors; Tumor Cells, Cultured | 1989 |
Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance.
Topics: Animals; Cell Survival; Female; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Quinazolines; Thymidylate Synthase | 1980 |
Use of 10-formyl-5,8-dideazafolate as substrate for rat 10-formyltetrahydrofolate dehydrogenase.
Topics: Acyltransferases; Animals; Folic Acid; Hydrolysis; Hydroxymethyl and Formyl Transferases; Leucovorin; Molecular Structure; NADP; Oxidoreductases Acting on CH-NH Group Donors; Phosphoribosylglycinamide Formyltransferase; Quinazolines; Rats; Spectrophotometry; Stereoisomerism | 1997 |
Quinoxaline chemistry. Part 10. Quinoxaline 10-oxa-analogues of trimetrexate (TMQ) and of 5,8-dideazafolic acid. Synthesis and evaluation of in vitro anticancer activity.
Topics: Antineoplastic Agents; Humans; Quinazolines; Quinoxalines; Structure-Activity Relationship; Trimetrexate; Tumor Cells, Cultured | 1998 |
Interligand Overhauser effects in type II dihydrofolate reductase.
Topics: Binding Sites; Catalysis; Escherichia coli; Folic Acid; Kinetics; Ligands; Macromolecular Substances; Nuclear Magnetic Resonance, Biomolecular; Quinazolines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2001 |
On the role of conserved histidine 106 in 10-formyltetrahydrofolate dehydrogenase catalysis: connection between hydrolase and dehydrogenase mechanisms.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Conserved Sequence; Folic Acid; Histidine; Hydrogen Bonding; Hydrolases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Protein Folding; Protein Structure, Tertiary; Quinazolines; Sequence Homology, Amino Acid | 2001 |
The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase.
Topics: Apoproteins; Binding Sites; Catalysis; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Escherichia coli Proteins; Folic Acid; Humans; Hydrogen-Ion Concentration; Hydroxymethyl and Formyl Transferases; Models, Molecular; Phosphoribosylglycinamide Formyltransferase; Protein Binding; Protein Structure, Tertiary; Quinazolines; Substrate Specificity | 2005 |