Page last updated: 2024-08-21

quinazolines and capsaicin

quinazolines has been researched along with capsaicin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (51.85)29.6817
2010's13 (48.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoshikuma, K; Kamiya, T; Kobayashi, Y; Nakano, Y; Yokoo, Y1
Hoshikuma, K; Kamiya, T; Kizaki, M; Kobayashi, Y; Nakano, Y; Yokoo, Y1
Deng, HW; Hu, CP; Li, YJ; Xiao, L1
Deng, HW; Hu, CP; Li, NS; Li, YJ; Xiao, L1
Kobayashi, Y1
Bizik, F; Blumberg, PM; Kedei, N; Kozikowski, AP; Pearce, LV; Petukhov, PA; Szabo, T1
Deng, PY; Hu, CP; Li, YJ; Tan, GS; Xu, KP; Yu, J1
Deng, HW; Du, YH; Hu, CP; Li, YJ; Peng, J; Rang, WQ; Xu, KP; Ye, F1
Baskin, EP; Corcoran, HA; Hargreaves, RJ; Hershey, JC; Kane, SA; Koblan, KS; Mosser, S; Salvatore, CA; Williams, TM1
Akerman, S; Goadsby, PJ; Gupta, S; Saxena, PR; van den Brink, AM; van den Maagdenberg, AM1
Avezaat, CJ; de Vries, R; Garrelds, IM; Gupta, S; Lozano-Cuenca, J; MaassenVanDenBrink, A; Saxena, PR; van Kats, JP; Villalón, CM1
de Hoon, JN; De Lepeleire, I; Depre, M; Kane, SA; Sinclair, SR; Van der Schueren, BJ; Van Hecken, A; Vanmolkot, FH1
Chen, Y; Miriel, VA; Rivers, RJ1
Bhatt, DK; Boni, LJ; Gupta, S; Olesen, J1
Fischer, MJ; Messlinger, K; Sixt, ML1
Bakthavatchalam, R; Blum, CA; Boyce, S; Brielmann, H; Burnaby-Davies, N; Caldwell, T; Capitosti, S; Chenard, BL; Conley, R; Cortright, D; Crandall, M; De Lombaert, S; Hodgetts, KJ; Jones, AB; Kershaw, MT; Krause, JE; Martin, WJ; Mason, G; Matson, D; Murphy, BA; Perrett, H; Rycroft, W; Zheng, X1
Chen, XP; Hu, CP; Li, D; Li, TT; Li, YJ; Peng, J; Wang, CJ; Zhou, Z1
Capó-Aponte, JE; Pan, Z; Reinach, PS; Wang, Z; Yang, H; Zhang, F1
Amrutkar, DV; Gupta, S; Hay-Schmidt, A; Jansen-Olesen, I; Mataji, A; Messlinger, K; Olesen, J; Salmasi, H; Sheykhzade, M1
Cavazzini, A; De Siena, G; Failli, P; Gees, M; Geppetti, P; Harrison, S; Mancini, F; Marchetti, N; Materazzi, S; Moretto, N; Nassini, R; Nilius, B; Patacchini, R; Pedretti, P; Preti, D1
Cheng, LC; Ching, LC; Kou, YR; Lee, TS; Pan, CC; Shyue, SK; Su, KH; Wei, J; Yu, YB1
Grandjean, PW; La Bounty, P; Leutholtz, B; Schwarz, NA; Spillane, M; Willoughby, DS1
Hishinuma, I; Ishii, N; Ohkuro, M; Shirato, M; Wakita, H1
Aoki, S; Dai, Y; Iwaoka, E; Kogure, Y; Matsuyoshi, N; Noguchi, K; Wang, S; Yamamoto, S1
Balboni, G; Byun, JS; Congiu, C; De Petrocellis, L; Deplano, A; Di Marzo, V; Garrido, M; Lee, JY; Messeguer, A; Onnis, V; Schiano Moriello, A; Sohn, JM; Vázquez-Romero, A; Zamponi, GW; Zhang, FX1
Dai, Y; Kogure, Y; Noguchi, K; Wang, S; Yamamoto, S; Zhang, W1
Aubdool, AA; Bátai, IZ; Brain, SD; Filotás, D; Hajna, Z; Helyes, Z; Nagy, L; Payrits, M; Pintér, E; Pozsgai, G; Sághy, É; Szőke, É1

Trials

2 trial(s) available for quinazolines and capsaicin

ArticleYear
Reproducibility of the capsaicin-induced dermal blood flow response as assessed by laser Doppler perfusion imaging.
    British journal of clinical pharmacology, 2007, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Analysis of Variance; Blood Flow Velocity; Capsaicin; Dose-Response Relationship, Drug; Forearm; Humans; Laser-Doppler Flowmetry; Male; Middle Aged; Piperazines; Quinazolines; Reproducibility of Results; Sensory System Agents; Skin; Treatment Outcome

2007
Capsaicin and evodiamine ingestion does not augment energy expenditure and fat oxidation at rest or after moderately-intense exercise.
    Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:12

    Topics: Adipose Tissue; Adolescent; Adult; Capsaicin; Capsicum; Cross-Over Studies; Energy Metabolism; Evodia; Exercise; Humans; Lipid Metabolism; Male; Oxidation-Reduction; Oxygen Consumption; Physical Exertion; Plant Extracts; Quinazolines; Rest; Thermogenesis; Young Adult

2013

Other Studies

25 other study(ies) available for quinazolines and capsaicin

ArticleYear
The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors.
    Planta medica, 2001, Volume: 67, Issue:3

    Topics: Alkaloids; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cardiotonic Agents; Dose-Response Relationship, Drug; Fruit; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Indole Alkaloids; Male; Myocardial Contraction; Plant Extracts; Platelet Aggregation Inhibitors; Purinergic Antagonists; Pyridoxal Phosphate; Quinazolines; Receptors, Drug; Rosales; Ruthenium Red; Stimulation, Chemical

2001
Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist.
    Planta medica, 2001, Volume: 67, Issue:7

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Temperature; Body Weight; Capsaicin; Cholesterol; Fatty Acids, Nonesterified; Fruit; Japan; Lipid Metabolism; Lipolysis; Liver; Male; Medicine, East Asian Traditional; Mice; Mice, Inbred C3H; Obesity; Phytotherapy; Plant Extracts; Plants, Medicinal; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rutaceae; Triglycerides

2001
The depressor and vasodilator effects of rutaecarpine are mediated by calcitonin gene-related peptide.
    Planta medica, 2003, Volume: 69, Issue:2

    Topics: Alkaloids; Animals; Aorta; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Evodia; Fruit; Indole Alkaloids; Injections, Intravenous; Injections, Subcutaneous; Male; Mesenteric Arteries; Phytotherapy; Quinazolines; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

2003
Involvement of capsaicin-sensitive sensory nerves in cardioprotection of rutaecarpine in rats.
    Regulatory peptides, 2003, Jun-15, Volume: 114, Issue:1

    Topics: Alkaloids; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cardiotonic Agents; Creatine Kinase; Heart; Indole Alkaloids; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Neurons, Afferent; Organ Size; Quinazolines; Rats; Rats, Wistar

2003
The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice.
    Planta medica, 2003, Volume: 69, Issue:5

    Topics: Acetic Acid; Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Evodia; Fruit; Ileum; Male; Mice; Mice, Inbred ICR; Motor Activity; Pain; Pain Measurement; Phytotherapy; Plant Extracts; Quinazolines

2003
Evodiamine functions as an agonist for the vanilloid receptor TRPV1.
    Organic & biomolecular chemistry, 2004, Aug-21, Volume: 2, Issue:16

    Topics: Animals; Calcium; Capsaicin; Cations, Divalent; CHO Cells; Cricetinae; Diterpenes; Ligands; Models, Biological; Molecular Conformation; Molecular Structure; Plant Extracts; Quinazolines; TRPV Cation Channels

2004
Involvement of CGRP in the inhibitory effect of rutaecarpine on vasoconstriction induced by anaphylaxis in guinea pig.
    Regulatory peptides, 2005, Feb-15, Volume: 125, Issue:1-3

    Topics: Alkaloids; Anaphylaxis; Animals; Antigens; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Capsaicin; Diphenhydramine; Female; Guinea Pigs; Indole Alkaloids; Male; Quinazolines; Receptors, Drug; Time Factors; TRPV Cation Channels; Vasoconstriction; Vasodilator Agents

2005
Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats.
    Planta medica, 2004, Volume: 70, Issue:12

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cardiotonic Agents; Creatine Kinase; Evodia; Infusions, Intravenous; Male; Myocardial Reperfusion Injury; Myocardium; Phytotherapy; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2004
Investigation of the species selectivity of a nonpeptide CGRP receptor antagonist using a novel pharmacodynamic assay.
    Regulatory peptides, 2005, Apr-15, Volume: 127, Issue:1-3

    Topics: Administration, Topical; Amino Acid Sequence; Animals; Biological Assay; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Dose-Response Relationship, Drug; Epidermis; Guinea Pigs; Humans; Intracellular Signaling Peptides and Proteins; Laser-Doppler Flowmetry; Macaca mulatta; Membrane Proteins; Molecular Sequence Data; Molecular Structure; Piperazines; Quinazolines; Rabbits; Rats; Receptor Activity-Modifying Proteins; Receptors, Calcitonin Gene-Related Peptide; Sequence Alignment; Vasodilation

2005
Intravital microscopy on a closed cranial window in mice: a model to study trigeminovascular mechanisms involved in migraine.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:11

    Topics: Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Disease Models, Animal; Dura Mater; Electric Stimulation; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Migraine Disorders; Piperazines; Quinazolines; Serotonin Receptor Agonists; Skull; Sumatriptan; Trigeminal Caudal Nucleus; Vasodilation

2006
Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Animals; Arteries; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Cyclic AMP; Dipeptides; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Piperazines; Piperidines; Potassium Channel Blockers; Potassium Chloride; Protein Kinase Inhibitors; Quinazolines; Swine; Vasodilation

2007
The involvement of CGRP, adrenomedullin, and sensory nerves in remote vasomotor responses within the hamster cheek pouch microcirculation.
    Microvascular research, 2009, Volume: 77, Issue:2

    Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Cheek; Cricetinae; Immunohistochemistry; Male; Mesocricetus; Methacholine Chloride; Microcirculation; Mouth Mucosa; Piperazines; Quinazolines; Receptors, Adrenomedullin; Receptors, Peptide; Sensory Receptor Cells; Vasodilation; Vasomotor System

2009
Improvement of the closed cranial window model in rats by intracarotid infusion of signalling molecules implicated in migraine.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:1

    Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Carotid Arteries; Cerebrovascular Circulation; Dipeptides; Disease Models, Animal; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Microscopy; Migraine Disorders; Piperazines; Pituitary Adenylate Cyclase-Activating Polypeptide; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents

2010
Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus.
    Brain : a journal of neurology, 2009, Volume: 132, Issue:Pt 11

    Topics: Animals; Biomarkers; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Dipeptides; Extracellular Signal-Regulated MAP Kinases; Humans; Male; Migraine Disorders; Neurons; Pain; Piperazines; Proto-Oncogene Proteins c-fos; Quinazolines; Rats; Rats, Wistar; Trigeminal Nucleus, Spinal

2009
Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists.
    Journal of medicinal chemistry, 2010, Apr-22, Volume: 53, Issue:8

    Topics: Analgesics; Animals; Biological Availability; Capsaicin; Chlorocebus aethiops; COS Cells; Hot Temperature; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Microsomes, Liver; Naphthyridines; Pain; Pyrazines; Pyridines; Pyrimidines; Quinazolines; Quinolines; Rats; Structure-Activity Relationship; TRPV Cation Channels

2010
Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide.
    Journal of hypertension, 2010, Volume: 28, Issue:5

    Topics: Adult; Adult Stem Cells; Angiotensin II; Animals; Base Sequence; Calcitonin Gene-Related Peptide; Capsaicin; Cellular Senescence; DNA Primers; Endothelial Cells; Female; Humans; Hypertension; In Vitro Techniques; Indole Alkaloids; Male; Middle Aged; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; TRPV Cation Channels

2010
Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.
    Experimental eye research, 2010, Volume: 91, Issue:3

    Topics: Benzoxazines; Blotting, Western; Capsaicin; Cell Movement; Cell Proliferation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; ErbB Receptors; Fluorescent Antibody Technique, Indirect; Humans; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Morpholines; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Piperidines; Pyrazoles; Quinazolines; Receptor, Cannabinoid, CB1; Transcriptional Activation; TRPV Cation Channels; Tyrphostins

2010
Evidence for CGRP re-uptake in rat dura mater encephali.
    British journal of pharmacology, 2010, Volume: 161, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium; Capsaicin; Dipeptides; Dura Mater; Male; Peptide Fragments; Piperazines; Quinazolines; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells

2010
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.
    Pain, 2011, Volume: 152, Issue:7

    Topics: Animals; Antineoplastic Agents; Atropine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Cells, Cultured; Chromatography, High Pressure Liquid; Cisplatin; Cricetinae; Cricetulus; Dipeptides; Disease Models, Animal; Drug Interactions; Ganglia, Spinal; Gene Expression Regulation; Guinea Pigs; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Knockout; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Piperazines; Pulmonary Artery; Quinazolines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensory Receptor Cells; Spectrometry, Mass, Electrospray Ionization; Superoxides; Tissue Culture Techniques; Transient Receptor Potential Channels; TRPA1 Cation Channel

2011
Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.
    Cardiovascular research, 2011, Aug-01, Volume: 91, Issue:3

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cattle; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; RNA Interference; Signal Transduction; Time Factors; Transfection; TRPV Cation Channels

2011
A putative antipruritic mechanism of the phosphodiesterase-4 inhibitor E6005 by attenuating capsaicin-induced depolarization of C-fibre nerves.
    Experimental dermatology, 2015, Volume: 24, Issue:3

    Topics: Action Potentials; Animals; Antipruritics; Capsaicin; Cyclic AMP; Ganglia, Spinal; Male; Nerve Fibers; Phosphodiesterase 4 Inhibitors; Phthalic Acids; Quinazolines; Rats; Rats, Wistar; TRPV Cation Channels

2015
Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels.
    Journal of natural medicines, 2016, Volume: 70, Issue:1

    Topics: Alkaloids; Analgesics; Animals; Calcium; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Evodia; Ganglia, Spinal; HEK293 Cells; Hot Temperature; Humans; Hyperalgesia; Male; Medicine, Chinese Traditional; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Plant Extracts; Quinazolines; Quinolines; Rats; Rats, Sprague-Dawley; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels

2016
Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel.
    Pharmacological research, 2015, Volume: 99

    Topics: Analgesics; Animals; Calcium; Capsaicin; Cell Line; Fever; HEK293 Cells; Humans; Pain; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Peptide; Triazines; TRPV Cation Channels

2015
Partial Activation and Inhibition of TRPV1 Channels by Evodiamine and Rutaecarpine, Two Major Components of the Fruits of Evodia rutaecarpa.
    Journal of natural products, 2016, 05-27, Volume: 79, Issue:5

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Evodia; Fruit; HEK293 Cells; Humans; Indole Alkaloids; Molecular Structure; Quinazolines; TRPV Cation Channels

2016
Capsaicin-Sensitive Sensory Nerves Mediate the Cellular and Microvascular Effects of H2S via TRPA1 Receptor Activation and Neuropeptide Release.
    Journal of molecular neuroscience : MN, 2016, Volume: 60, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cell Line; Cells, Cultured; Dipeptides; Diterpenes; Female; Glyburide; Hydrogen Sulfide; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Potassium Chloride; Quinazolines; Receptors, Neurokinin-1; Sensory Receptor Cells; Substance P; Transient Receptor Potential Channels; Trigeminal Ganglion; TRPA1 Cation Channel; Vasodilation

2016