quinazolines has been researched along with aspirin in 75 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 20 (26.67) | 18.7374 |
1990's | 6 (8.00) | 18.2507 |
2000's | 31 (41.33) | 29.6817 |
2010's | 16 (21.33) | 24.3611 |
2020's | 2 (2.67) | 2.80 |
Authors | Studies |
---|---|
Diamantis, W; Ludwig, BJ; Sofia, RD | 1 |
Ferber, RH; Parrish, SL; Vigdahl, RL | 1 |
Hill, RC; van Graffenried, B | 1 |
Holmes, IB | 1 |
Buchanan, JO; Buyniski, JP; Fleming, JS | 1 |
Komatsu, T; Yanagi, Y | 1 |
Chintagumpala, MM; Fernbach, DJ; Mahoney, DH; Ogden, AK; Steuber, CP | 1 |
Itoh, T; Kambayashi, J; Mori, T; Sakon, M; Tsujinaka, T; Uemura, Y | 1 |
Matsumoto, M | 1 |
Böhm, R | 1 |
Isomäki, H; Laitinen, O; Nissilä, M; Nuotio, P; Nykänen, E; Seppälä, E; Vapaatalo, H | 1 |
Feldman, S; Goldstein, P; London, R; Sundaram, GS | 1 |
Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
Fankhauser, S; Laube, W; Marti, HR; Schultheiss, HR; Vögtlin, J; von Graffenried, B | 1 |
Gillberg, RE; Korsan-Bengtsen, K; Magnusson, B; Nyberg, G; Schütz, W | 1 |
Beveridge, T; Crawford, M | 1 |
Gillberg, R; Korsan-Bengtsen, K; Magnusson, B; Nyberg, G | 1 |
Berger, M; Herrmann, U; Laube, W; Nüesch, E; Roth, F; Schultheiss, HR; Schürmann, P; von Graffenried, B | 1 |
Forbes, JA; Hughes, MK; White, EH; White, RW | 1 |
von Graffenried, B; Wood, AJ | 1 |
Clark, WF; Moriarity, TA; Reid, BD; Tevaarwerk, GJ | 1 |
Mughal, TI | 1 |
Ishizuka, Y; Kamisaki, T; Kawase, A; Sato, M; Shimamura, H; Tanaka, Y; Tanimura, T; Terashima, K | 1 |
Maricic, N; Peskar, BM | 1 |
Silverstein, MN; Tefferi, A | 1 |
Green, AR | 1 |
Hung, WC; Lee, YM; Sheu, JR; Wu, CH; Yen, MH | 1 |
Akaike, T; Egashira, K; Funakoshi, H; Huang, P; Kandabashi, T; Miyata, K; Okamoto, S; Shimokawa, H; Takeshita, A; Yogo, K | 1 |
Briere, J; Guilmin, F | 1 |
Bangerter, M; Griesshammer, M; Grünewald, M | 1 |
Tefferi, A; Wright, CA | 1 |
Solberg, LA | 1 |
Griesshammer, M; Langer, C | 1 |
Bartell, S; Mahajan, S; Tibbles, HE; Uckun, FM; Vassilev, A; Zheng, Y | 1 |
Schafer, AI | 1 |
Putti, MC; Randi, ML | 1 |
Deng, PY; Ding, JS; Hu, CP; Li, YJ; Shen, SS; Tan, GS; Wang, L; Zhu, HQ | 1 |
Bareford, D; Buck, G; Campbell, PJ; East, CL; Green, AR; Grigg, AP; Harrison, CN; Reilly, JT; Revell, P; van der Walt, JD; Wheatley, K; Wilkins, BS; Woodcock, BE | 1 |
Barbui, T; Finazzi, G | 2 |
Costello, R; O'Callaghan, T; Sébahoun, G | 1 |
Fishman, DA; Kang, S; Luo, R; Meng, Y; Smicun, Y | 1 |
Kanazawa, S; Kinoshita, Y; Komiyama, Y; Muramatsu, M; Nomura, S; Yamaguchi, K | 1 |
Petrides, PE | 2 |
Gisslinger, H | 1 |
Becker, JC; Berdel, WE; Brandts, C; Domschke, W; Fujimori, T; Ilea, AM; Müller-Tidow, C; Pohle, T; Serve, H; Stolte, M; Tickenbrock, L; Tidow, N | 1 |
Reilly, JT | 1 |
Bareford, D; Buck, G; Campbell, PJ; East, CL; Erber, WN; Green, AR; Harrison, CN; Paul, B; Wheatley, K; Wilkins, BS | 1 |
Cacciola, E; Cacciola, RR; Di Francesco, E; Giustolisi, R; Pezzella, F; Tibullo, D | 1 |
Kubo, K | 1 |
Birgegård, G | 1 |
Sundermeyer, M; Veeraputhiran, M | 1 |
Bengtsson, T; Grenegård, M; Lindahl, TL; Nylander, M | 1 |
Hanayama, K; Hirashima, T; Imamura, F; Kanazawa, S; Kinoshita, Y; Nomura, S; Sasada, S; Siomi, K; Tujimoto, M; Yamaguchi, K | 1 |
Beer, PA; Green, AR | 1 |
Ishar, MP; Paneerselvam, P; Raj, T; Rather, BA; Reddy, A; Sivakumar, S | 1 |
Demulder, AC; Malarme, M; Mesquita, Mdo C; Noubouossie, D; Sol, EB | 1 |
Grubbs, CJ; Juliana, MM; Lubet, RA; Steele, VE | 1 |
Vannucchi, AM | 1 |
Dowson, A; Frewin, R | 1 |
Alvarez-Larrán, A; Besses, C; Cervantes, F | 1 |
Haznedaroglu, IC | 1 |
Barthwal, MK; Khaliq, T; Mishra, V; Narender, T; Palit, G; Pandey, HP; Singh, VK; Tiwari, S | 1 |
Balasubramaniam, K; Dragone, J; Grose-Hodge, R; Martin, P; Preston, P; Troy, S; Viswanathan, G; Zaman, AG | 1 |
Birnbaum, Y; Kodakandla, M; Ling, S; Nanhwan, MK; Nylander, S; Ye, Y | 1 |
Miyamoto, T; Yoshimoto, G | 1 |
Brychtová, Y; Campr, V; Černá, O; Červinek, L; Cmunt, E; Doubek, M; Dulíček, P; Kissová, J; Křen, L; Maaloufová Soukupová, J; Ovesná, P; Penka, M; Schwarz, J | 1 |
Hoffman, R; Kremyanskaya, M; Mascarenhas, J | 1 |
Fujimura, K; Shimazu, Y | 1 |
Demeter, J; Dombi, P; Egyed, M; Homor, L; Illés, Á; Karadi, E; Simon, Z; Udvardy, M | 1 |
Corvetta, D; Di Pierro, AM; Eakins, E; Feistritzer, C; Gambato, R; Gastl, G; Gherlinzoni, F; Gottardi, M; Krampera, M; Langes, M; Marcheselli, L; Mazzoleni, G; Mega, A; Murphy, C; Pacquola, E; Perbellini, O; Piccin, A; Piva, E; Plebani, M; Pusceddu, I; Steurer, M; Tauber, M; Van Schilfgaarde, M; Veneri, D | 1 |
Usui, N | 1 |
Arimura, A; Fujii, K; Hashiguchi, T; Hayashida, M; Higashi, Y; Kanekura, T | 1 |
Demeter, J; Dombi, P; Egyed, M; Ercsei, I; Gasztonyi, Z; Gy Korom, V; Herczeg, J; Homor, L; Illes, A; Karadi, E; Kellner, A; Simon, Z; Szerafin, L; Udvardy, M | 1 |
24 review(s) available for quinazolines and aspirin
Article | Year |
---|---|
[Thrombocyte aggregation inhibitors--a new class of active substances. 2. Chemical and pharmacologic aspects of some agents].
Topics: Anti-Inflammatory Agents; Aspirin; Chemical Phenomena; Chemistry; Dipyridamole; Heterocyclic Compounds; Humans; Imidazoles; Phthalazines; Platelet Aggregation; Pyridazines; Pyridines; Pyrimidines; Quinazolines; Quinolines; Sulfinpyrazone | 1986 |
Primary thrombocythemia: a current perspective.
Topics: Aspirin; Diagnosis, Differential; Humans; Hydroxyurea; Interferon Type I; Myeloproliferative Disorders; Platelet Aggregation Inhibitors; Plateletpheresis; Quinazolines; Recombinant Proteins; Thrombocytosis | 1995 |
Role of prostaglandins in gastroprotection.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Gastric Mucosa; Humans; Prostaglandins; Quinazolines; Stomach Ulcer | 1998 |
Treatment of polycythaemia vera and essential thrombocythaemia.
Topics: Adult; Aged; Aspirin; Chlorambucil; Disease Progression; Female; Hemorrhage; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Middle Aged; Phlebotomy; Phosphorus Radioisotopes; Pipobroman; Polycythemia Vera; Primary Myelofibrosis; Prospective Studies; Quinazolines; Thrombocythemia, Essential; Thrombosis | 1998 |
The pathogenesis and management of essential thrombocythaemia.
Topics: Acute Disease; Alkylating Agents; Aspirin; Cardiovascular Diseases; Clone Cells; Gene Expression; Hemorrhage; Humans; Hydroxyurea; Leukemia, Myeloid; Megakaryocytes; Platelet Aggregation Inhibitors; Quinazolines; Risk; Thrombocythemia, Essential; Thrombophilia | 1999 |
Management of patients with essential thrombocythemia: current concepts and perspectives.
Topics: Adult; Aged; Aspirin; Case Management; Clinical Trials as Topic; Diagnosis, Differential; Disease Progression; Female; Hemorrhagic Disorders; Humans; Hydroxyurea; Interferons; Leukemia; Male; Middle Aged; Pipobroman; Platelet Aggregation Inhibitors; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; Quinazolines; Risk; Safety; Thrombocythemia, Essential; Thrombophilia | 2001 |
Current treatment practice for essential thrombocythaemia in adults.
Topics: Adult; Aspirin; Humans; Hydroxyurea; Interferon-alpha; Pipobroman; Prognosis; Quinazolines; Thrombocythemia, Essential | 2001 |
A single institutional experience with 43 pregnancies in essential thrombocythemia.
Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Anticoagulants; Aspirin; Busulfan; Erythromelalgia; Female; Fetal Death; Follow-Up Studies; Heparin; Humans; Hydroxyurea; Migraine Disorders; Obstetric Labor, Premature; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Platelet Count; Plateletpheresis; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Pregnancy Trimester, First; Pregnancy, Ectopic; Pregnancy, High-Risk; Quinazolines; Retrospective Studies; Risk; Thrombocythemia, Essential; Uterine Hemorrhage | 2001 |
Therapeutic options for essential thrombocythemia and polycythemia vera.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Busulfan; Fibrinolytic Agents; Humans; Hydroxyurea; Immunologic Factors; Immunosuppressive Agents; Interferon-alpha; Nucleic Acid Synthesis Inhibitors; Phosphorus Radioisotopes; Polycythemia Vera; Quinazolines; Risk Assessment; Thrombocytosis | 2002 |
Pharmacotherapy of essential thrombocythaemia: economic considerations.
Topics: Age Factors; Antineoplastic Agents; Aspirin; Clinical Trials, Phase II as Topic; Cost-Benefit Analysis; Humans; Hydroxyurea; Interferon-alpha; Pipobroman; Quinazolines; Risk Factors; Thrombocythemia, Essential | 2003 |
Thrombocytosis.
Topics: Aspirin; Clone Cells; Diagnosis, Differential; Humans; Hydroxyurea; Interferon-alpha; Plasmapheresis; Platelet Aggregation Inhibitors; Quinazolines; Thrombocythemia, Essential; Thrombocytosis | 2004 |
[Treatment of essential thrombocythemia].
Topics: Aspirin; Enzyme Inhibitors; Hemorrhage; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Platelet Aggregation Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Risk Factors; Thrombocythemia, Essential | 2005 |
Anagrelide: what was new in 2004 and 2005?
Topics: Antineoplastic Agents; Aspirin; Blood Platelets; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hemorrhage; History, 21st Century; Humans; Hydroxyurea; Male; Megakaryocytes; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Randomized Controlled Trials as Topic; Signal Transduction; Thrombocythemia, Essential | 2006 |
Update on diagnosis and management of essential thrombocythemia.
Topics: Age Factors; Antineoplastic Agents; Aspirin; Drug Antagonism; Female; Fibrinolytic Agents; Hemorrhage; Humans; Hydroxyurea; Interferon-alpha; Life Expectancy; Male; Quinazolines; Risk Factors; Thrombocythemia, Essential | 2006 |
[Primary thrombocythemia: diagnosis and therapy].
Topics: Adult; Aged; Aspirin; Child; Diagnosis, Differential; Drug Therapy, Combination; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Male; Mutation; Platelet Aggregation Inhibitors; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Primary Prevention; Prospective Studies; Quinazolines; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Thrombocythemia, Essential; Time Factors | 2006 |
[Drug-induced pulmonary edema].
Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Gefitinib; Glucocorticoids; Humans; Immunosuppressive Agents; Norepinephrine; Pulmonary Edema; Quinazolines; Respiration, Artificial; Risk Factors | 2007 |
Evidence and expertise in the management of polycythemia vera and essential thrombocythemia.
Topics: Aspirin; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Mutation; Phlebotomy; Polycythemia Vera; Quinazolines; Risk Factors; Survival Analysis; Thrombocythemia, Essential | 2008 |
Long-term management of thrombocytosis in essential thrombocythaemia.
Topics: Algorithms; Antineoplastic Agents; Aspirin; Female; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Pregnancy; PubMed; Quinazolines; Randomized Controlled Trials as Topic; Thrombocythemia, Essential; Thrombocytosis | 2009 |
Pathogenesis and management of essential thrombocythemia.
Topics: Acute Disease; Aged; Aspirin; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyurea; Interferon-alpha; Janus Kinase 2; Leukemia, Myeloid; Middle Aged; Models, Biological; Mutation, Missense; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Protein Kinase Inhibitors; Quinazolines; Thrombocythemia, Essential; Thrombophilia | 2009 |
JAK2 mutation and thrombosis in the myeloproliferative neoplasms.
Topics: Amino Acid Substitution; Aspirin; Cardiovascular Diseases; Clinical Trials as Topic; Fibrinolytic Agents; Humans; Incidence; Interferon-alpha; Janus Kinase 2; Multicenter Studies as Topic; Mutation, Missense; Myeloproliferative Disorders; Phenotype; Point Mutation; Quinazolines; Thrombophilia; Thrombosis | 2010 |
Headache in essential thrombocythaemia.
Topics: Alkylating Agents; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Headache Disorders; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Quinazolines; Radiopharmaceuticals; Risk Factors; Thrombocythemia, Essential | 2012 |
[Treatment of essential thrombocythemia].
Topics: Adult; Age Factors; Aged; Anticoagulants; Aspirin; Cell Transformation, Neoplastic; Disease Progression; Female; Hemorrhage; Heparin, Low-Molecular-Weight; Humans; Hydroxyurea; Intraoperative Complications; Janus Kinase 2; Leukemia, Myeloid, Acute; Life Expectancy; Male; Middle Aged; Mutation, Missense; Platelet Aggregation Inhibitors; Point Mutation; Pregnancy; Pregnancy Complications, Hematologic; Primary Myelofibrosis; Quinazolines; Risk Factors; Thrombocythemia, Essential; Thrombophilia | 2013 |
[Treatment strategy for myeloproliferative neoplasms].
Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy, Combination; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Immunosuppressive Agents; Janus Kinase 2; Molecular Targeted Therapy; Mutation; Nitriles; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Pyrazoles; Pyrimidines; Quinazolines; Receptors, Thrombopoietin; Thalidomide; Thrombocythemia, Essential | 2014 |
Anagrelide hydrochloride and ruxolitinib for treatment of polycythemia vera.
Topics: Aspirin; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Nitriles; Platelet Aggregation Inhibitors; Polycythemia Vera; Polyethylene Glycols; Pyrazoles; Pyrimidines; Quinazolines | 2015 |
13 trial(s) available for quinazolines and aspirin
Article | Year |
---|---|
Headache as a model for testing mild analgesics.
Topics: Adult; Aminopyrine; Analgesics; Antipyrine; Aspirin; Barbiturates; Caffeine; Clinical Trials as Topic; Dihydroergotamine; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Headache; Humans; Male; Placebos; Quinazolines | 1978 |
Episiotomy pain: efficacy and safety of fluproquazone compared to aspirin and placebo.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Episiotomy; Female; Humans; Pain, Postoperative; Prospective Studies; Quinazolines; Quinazolinones; Random Allocation | 1983 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
Antipyretic activity of fluproquazone in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Female; Fever; Humans; Male; Middle Aged; Quinazolines; Quinazolinones | 1981 |
Gastrointestinal blood loss, gastroscopy and coagulation factors in normal volunteers during administration of acetylsalicylic acid and fluproquazone.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Tests; Feces; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hemostasis; Humans; Male; Quinazolines; Quinazolinones | 1981 |
Analgesic effect of fluproquazone in postoperative patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Episiotomy; Female; Humans; Male; Middle Aged; Pain, Postoperative; Quinazolines; Quinazolinones | 1980 |
An evaluation of the analgesic efficacy of proquazone and aspirin in postoperative dental pain.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Pain, Postoperative; Quinazolines; Tooth, Impacted | 1980 |
Fluproquazone: analgesic activity in outpatients with non-migrainous headache.
Topics: Adult; Aged; Analgesics; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Placebos; Quinazolines; Quinazolinones; Time Factors | 1981 |
Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Primary Myelofibrosis; Quinazolines; Thrombocythemia, Essential; Thrombosis | 2005 |
Aspirin reduces adverse effects of gefitinib.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Female; Gefitinib; Humans; Lung Neoplasms; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Quinazolines; Thromboxane B2 | 2006 |
Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
Topics: Adult; Antineoplastic Agents; Aspirin; Biopsy; Blood Cell Count; Drug Therapy, Combination; Hematology; Humans; Hydroxyurea; Megakaryocytes; Observer Variation; Pathology, Clinical; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prospective Studies; Quinazolines; Thrombocytosis | 2008 |
Effect of anagrelide on platelet coagulant function in patients with essential thrombocythemia.
Topics: Adult; Aged; Antithrombin III; Aspirin; Drug Therapy, Combination; Female; Fibrin Fibrinogen Degradation Products; Hemorrhage; Humans; Hydroxyurea; Male; Middle Aged; Peptide Fragments; Peptide Hydrolases; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Factor 4; Prothrombin; Quinazolines; Thrombocythemia, Essential; Thrombosis | 2007 |
Antithrombotic properties of rafigrelide: a phase 1, open-label, non-randomised, single-sequence, crossover study.
Topics: Adult; Aspirin; Blood Coagulation; Blood Platelets; Cross-Over Studies; Drug Therapy, Combination; Headache; Humans; Imidazoles; Male; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Thrombelastography; Thrombocytopenia; Thrombosis | 2014 |
38 other study(ies) available for quinazolines and aspirin
Article | Year |
---|---|
Pharmacological properties of 2,3-dihydro-9H-isoxazolo [3,2-b] quinazolin-9-one (W-2429. Part 1: Analgesic, antipyretic and antiedema activity.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Body Temperature; Dextropropoxyphene; Drug Interactions; Drug Tolerance; Edema; Fever; Humans; Injections, Intravenous; Isoxazoles; Lethal Dose 50; Male; Mice; Narcotic Antagonists; Oxazoles; Quinazolines; Rats; Substance-Related Disorders; Time Factors | 1977 |
Evaluation of antiinflammatory and antithrombotic drugs in pulmonary and arterial thrombosis.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Anti-Inflammatory Agents; Arterial Occlusive Diseases; Aspirin; Benzophenones; Carotid Arteries; Cattle; Dipyridamole; Drug Evaluation; Fibrinolytic Agents; Humans; Imidazoles; Indoles; Indomethacin; Lung Diseases, Obstructive; Male; Mice; Platelet Aggregation; Prostaglandins; Pyridines; Quinazolines; Rats; Sulfinpyrazone; Sulfonamides; Suloctidil; Thiophenes | 1979 |
A comparison of the effect of proquazone, a new non-steroidal antiinflammatory compound, compound, and acetylsalicylic acid on blood platelet function in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Bronchial Spasm; Collagen; Guinea Pigs; In Vitro Techniques; Platelet Aggregation; Quinazolines; Rabbits; Serotonin; Time Factors | 1977 |
The effect of a potent inhibitor of platelet aggregation, BL-3459, on adrenaline-induced myocardial necrosis in beagle dogs.
Topics: Animals; Aspirin; Blood Pressure; Disease Models, Animal; Dogs; Epinephrine; Female; Imidazoles; Male; Myocardial Infarction; Necrosis; Phenoxybenzamine; Platelet Aggregation; Propranolol; Quinazolines | 1976 |
Inhibition of prostaglandin biosynthesis by SL-573.
Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Depression, Chemical; In Vitro Techniques; Indomethacin; Kinetics; Male; Microsomes; Prostaglandins; Prostaglandins E; Quinazolines; Quinazolinones; Seminal Vesicles | 1976 |
Essential thrombocythemia in a child: management with anagrelide.
Topics: Aspirin; Child; Drug Therapy, Combination; Humans; Male; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Thrombocythemia, Essential | 1991 |
Clinical application of a new in vitro bleeding time device on surgical patients.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aspirin; Bleeding Time; Epoprostenol; Hemorrhage; Hemostasis; Humans; Liver Cirrhosis; Platelet Aggregation Inhibitors; Platelet Function Tests; Postoperative Complications; Quinazolines; Skin; Thrombocytopenia; Ticlopidine | 1988 |
[Behavior of platelets and leukocytes on the luminal surface of small caliber prosthetic grafts].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aspirin; Blood Vessel Prosthesis; Cell Adhesion; Dogs; Graft Occlusion, Vascular; Leukocytes; Microscopy, Electron, Scanning; Platelet Adhesiveness; Polytetrafluoroethylene; Quinazolines; Thrombosis | 1988 |
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Dinoprostone; Guanidines; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Prednisolone; Prostaglandins; Prostaglandins E; Quinazolines; Synovial Fluid; Thromboxane B2 | 1985 |
Controlled comparison of gastric lesions and gastrointestinal blood loss with fluproquazone and acetylsalicylic acid (ASA) in healthy subjects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Factors; Blood Platelets; Female; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; Quinazolines; Quinazolinones; Stomach Ulcer | 1981 |
Effects of fluproquazone on platelet aggregation in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Collagen; Female; Humans; Male; Middle Aged; Platelet Aggregation; Quinazolines; Quinazolinones | 1981 |
Inhibitors of immune complex induced human platelet aggregation and release in plasma.
Topics: Antibodies; Antigen-Antibody Complex; Aspirin; Blood Platelets; Depression, Chemical; Dipyridamole; DNA; Humans; Imidazoles; Indomethacin; Lupus Erythematosus, Systemic; Male; Platelet Aggregation; Quinazolines; Receptors, Fc; Sulfinpyrazone | 1982 |
Studies on antiulcer agents. IV. Antiulcer effects of 2-benzylthio5,6,7,8-tetrahydro-4(3H)-quinazolinones and related compounds.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Disease Models, Animal; Duodenal Ulcer; Epirizole; Ethanol; Gastric Acid; Gastric Mucosa; Histamine; Indomethacin; Male; Quinazolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship | 1995 |
Antithrombotic effect of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, on platelet plug formation in in vivo experiments.
Topics: Adenosine Diphosphate; Alkaloids; Animals; Aspirin; Bleeding Time; Blood Pressure; Drugs, Chinese Herbal; Fluorescein; Indole Alkaloids; Mice; Mice, Inbred ICR; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Embolism; Quinazolines; Rats; Rats, Sprague-Dawley | 2000 |
Different vasculoprotective roles of NO synthase isoforms in vascular lesion formation in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aspirin; Carotid Arteries; Female; Fibrinolytic Agents; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Quinazolines; Tunica Intima | 2000 |
The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism.
Topics: Adenosine Diphosphate; Agammaglobulinaemia Tyrosine Kinase; Amides; Animals; Aspirin; Bleeding Time; Catalytic Domain; Collagen; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fibrinolytic Agents; Humans; Janus Kinase 3; Male; Mice; Mice, Inbred ICR; Nitriles; Peptide Fragments; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pulmonary Embolism; Quinazolines; Receptors, Collagen; Signal Transduction; Thrombin; Thromboembolism; Thromboplastin | 2003 |
Essential thrombocythaemia in children: is a treatment needed?
Topics: Adult; Aspirin; Child; Clinical Trials, Phase II as Topic; Humans; Interferon-alpha; Quinazolines; Thrombocythemia, Essential | 2004 |
The protective effects of rutaecarpine on gastric mucosa injury in rats.
Topics: Alkaloids; Animals; Anti-Ulcer Agents; Aspirin; Disease Models, Animal; Evodia; Female; Gastric Mucosa; Indole Alkaloids; Male; Phytotherapy; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 2005 |
When and how to treat essential thrombocythemia.
Topics: Antineoplastic Agents; Aspirin; Drug Therapy, Combination; Hemorrhage; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Platelet Aggregation Inhibitors; Primary Myelofibrosis; Quinazolines; Risk Factors; Thrombocythemia, Essential; Thrombosis | 2005 |
Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation.
Topics: Animals; Antigen Presentation; Antigens, Surface; Apoptosis; Aspirin; Cell Line, Tumor; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Female; Flavonoids; Humans; Lymphocyte Activation; Lymphocytes; Lysophospholipids; Membrane Glycoproteins; Nitrobenzenes; Ovarian Neoplasms; Quinazolines; Signal Transduction; Sulfonamides; Tumor Necrosis Factors; Tyrphostins | 2006 |
Acetylsalicylic acid enhances antiproliferative effects of the EGFR inhibitor gefitinib in the absence of activating mutations in gastric cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Blotting, Western; Cell Survival; Drug Synergism; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Gene Expression Profiling; Humans; Middle Aged; Mutation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stomach Neoplasms; Tumor Cells, Cultured | 2006 |
Practical approach to treating essential thrombocythaemia: case studies.
Topics: Adult; Aspirin; Disease Management; Female; Humans; Hydroxyurea; Interferon-alpha; Leg Ulcer; Male; Middle Aged; Pipobroman; Platelet Count; Pregnancy; Pregnancy Complications, Hematologic; Quinazolines; Thrombocythemia, Essential; Warfarin | 2007 |
Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin.
Topics: Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atenolol; Azetidines; Carcinoma, Non-Small-Cell Lung; Coronary Artery Disease; Drug Interactions; Erlotinib Hydrochloride; Ezetimibe; Female; Humans; Hyperlipidemias; Hypertension; Lung Neoplasms; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Quinazolines; Rhabdomyolysis; Simvastatin; Tomography, X-Ray Computed | 2008 |
The periodontal pathogen Porphyromonas gingivalis sensitises human blood platelets to epinephrine.
Topics: Adhesins, Bacterial; Apyrase; Aspirin; Blood Platelets; Calcium Signaling; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Epinephrine; Gingipain Cysteine Endopeptidases; Humans; In Vitro Techniques; Leupeptins; Nephelometry and Turbidimetry; Oligopeptides; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Porphyromonas gingivalis; Protease Inhibitors; Pyrroles; Quinazolines; Receptors, Proteinase-Activated; Virulence; Yohimbine | 2008 |
Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer.
Topics: Aged; Aspirin; Dose-Response Relationship, Drug; Erlotinib Hydrochloride; Exanthema; Female; Humans; Lung Neoplasms; Male; Platelet Activation; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Quinazolines; Thromboxane B2; Treatment Outcome | 2009 |
Synthesis and evaluation of novel 2-substituted-quinazolin-4(3H)-ones as potent analgesic and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Disease Models, Animal; Female; Indomethacin; Inflammation; Male; Mice; Pain; Pain Measurement; Quinazolines; Structure-Activity Relationship | 2010 |
Management of refractory essential thrombocythemia with anagrelide in a patient undergoing hemodialysis.
Topics: Aged; Aspirin; Blood Cell Count; Blood Chemical Analysis; Blood Transfusion; Drug Resistance; Erythropoietin; Fatal Outcome; Female; Humans; Hydroxyurea; Jehovah's Witnesses; Kidney Failure, Chronic; Kidney Function Tests; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Recombinant Proteins; Renal Dialysis; Thrombocythemia, Essential | 2009 |
Screening agents for preventive efficacy in a bladder cancer model: study design, end points, and gefitinib and naproxen efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Gefitinib; Naproxen; Quinazolines; Rats; Rats, Inbred F344; Research Design; Resveratrol; Stilbenes; Urinary Bladder Neoplasms | 2010 |
The therapeutic goals of essential thrombocythemia under the clouds of over-treatment and under-treatment.
Topics: Aspirin; Fibrinolytic Agents; Humans; Hydroxyurea; Interferon-alpha; Platelet Aggregation Inhibitors; Quinazolines; Risk Assessment; Thrombocythemia, Essential | 2013 |
Anti-secretory and cyto-protective effects of peganine hydrochloride isolated from the seeds of Peganum harmala on gastric ulcers.
Topics: Alcohols; Alkaloids; Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Cold Temperature; Disease Models, Animal; H(+)-K(+)-Exchanging ATPase; Male; Molecular Structure; Omeprazole; Peganum; Plant Extracts; Pylorus; Quinazolines; Rats; Rats, Sprague-Dawley; Seeds; Stomach Ulcer; Sucralfate | 2013 |
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Aspirin; Cardiotonic Agents; Clopidogrel; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Induction; Lipoxins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Pyrazoles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Ticagrelor; Ticlopidine; Triazoles; Up-Regulation | 2014 |
Thrombosis in thrombocythemic Ph- myeloproliferations is associated with higher platelet count prior to the event: results of analyses of prothrombotic risk factors from a registry of patients treated with anagrelide.
Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Aspirin; Female; Fusion Proteins, bcr-abl; Humans; Janus Kinase 2; Male; Mutation, Missense; Philadelphia Chromosome; Platelet Count; Prospective Studies; Quinazolines; Registries; Risk Factors; Thrombocytosis; Thrombosis | 2016 |
Acute pancreatitis as a side effect of anagrelide hydrochloride hydrate: a case report.
Topics: Abdominal Pain; Acute Disease; Aged; Aspirin; Drug Substitution; Female; Humans; Hydroxyurea; Janus Kinase 2; Mutation; Pancreatitis; Phosphodiesterase Inhibitors; Quinazolines; Thrombocythemia, Essential | 2016 |
Anagrelide reduces thrombotic risk in essential thrombocythaemia vs. hydroxyurea plus aspirin.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hungary; Hydroxyurea; Male; Middle Aged; Platelet Aggregation Inhibitors; Quinazolines; Risk; Thrombocythemia, Essential; Thrombosis | 2017 |
Observational retrospective study of vascular modulator changes during treatment in essential thrombocythemia.
Topics: Adrenomedullin; Aged; Aspirin; Blood Platelets; Case-Control Studies; Cell-Derived Microparticles; Endothelin-1; Endothelium, Vascular; Female; Humans; Hydroxyurea; Male; Middle Aged; Nitric Oxide; Quinazolines; Retrospective Studies; Thrombocythemia, Essential | 2017 |
JSH guideline for tumors of hematopoietic and lymphoid tissues-lukemia: 4. Chronic myelogenous leukemia (CML)/myeloproliferative neoplasms (MPN).
Topics: Algorithms; Aniline Compounds; Antineoplastic Agents; Aspirin; Blood Transfusion; Dasatinib; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Imidazoles; Japan; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloproliferative Disorders; Nitriles; Phlebotomy; Prognosis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyridazines; Pyrimidines; Quinazolines; Quinolines; Risk | 2017 |
Anagrelide with low-dose aspirin promptly epithelized ulceronecrotic lesion secondary to essential thrombocythemia.
Topics: Aspirin; Bone Marrow; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Janus Kinase 2; Karyotyping; Male; Middle Aged; Mutation; Necrosis; Quinazolines; Re-Epithelialization; Skin; Skin Ulcer; Thrombocythemia, Essential; Toes; Treatment Outcome | 2020 |
Anagrelide influences thrombotic risk, and prolongs progression-free and overall survival in essential thrombocythaemia vs hydroxyurea plus aspirin.
Topics: Aspirin; Drug Therapy, Combination; Health Care Surveys; Humans; Hungary; Hydroxyurea; Quinazolines; Registries; Thrombocythemia, Essential; Thrombosis; Treatment Outcome | 2020 |