Page last updated: 2024-08-21

quinazolines and ascorbic acid

quinazolines has been researched along with ascorbic acid in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Alvarez, R; Kenley, RA; Lin, LH; Venuti, MC; Visor, GC1
De Robertis, E; Levi de Stein, M; Wolfman, C1
Fujiwara, M; Noda, K; Saita, M; Soejima, Y; Takamori, M; Tsuji, M; Ueki, S1
Becker, B; Feitl, M; Krupin, T1
Bilgili, SF; Hess, JB; Pinion, JL1
Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H1
García-Martín, E; Gutiérrez-Merino, C; Martín-Romero, FJ1
Amano, O; Chu, Q; Kanda, Y; Kunii, S; Sakagami, H; Wang, Q1
Chen, X; Feng, S; Ji, P; Li, LL; Luo, SD; Ma, S; Pan, YL; Wang, ZR; Wei, YQ; Yang, SY; Zhong, L; Zhou, JP1
Bazzan, AJ; Deshmukh, S; Levine, M; Littman, S; Mitchell, E; Monti, DA; Newberg, AB; Pillai, MV; Yeo, CJ; Zabrecky, G1
Appadurai, DA; Manning, J; May, JM; Mitchell, B; Nganga, V; Pierce, LJ; Shakya, A; Spangrude, GJ; Swanson, PC; Tantin, D; Wang, H1
Aoki, I; Bakalova, R; Getsov, P; Ivanova, D; Lazarova, D; Zhelev, Z1
Benites, J; Buc Calderon, P; Muccioli, GG; Ríos, D; Valderrama, JA1

Trials

1 trial(s) available for quinazolines and ascorbic acid

ArticleYear
Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Gemcitabine; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Pulmonary Embolism; Quinazolines; Treatment Outcome

2012

Other Studies

12 other study(ies) available for quinazolines and ascorbic acid

ArticleYear
Electrochemical evaluation of the interaction between ascorbic acid and the cardiotonic drug RS-82856.
    Drug design and delivery, 1987, Volume: 2, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Ascorbic Acid; Cardiotonic Agents; Drug Interactions; Electrochemistry; Platelet Aggregation Inhibitors; Quinazolines; Quinolones; Solutions

1987
Time course of changes in [3H]prazosin binding after catecholaminergic denervation by 6-hydroxydopamine in rat cerebral cortex. Inhibitory effects of ascorbic acid on the alpha 1-adrenoceptor.
    Neuropharmacology, 1983, Volume: 22, Issue:9

    Topics: Animals; Ascorbic Acid; Brain; Catecholamines; Clonidine; Female; Hydroxydopamines; Kinetics; Male; Oxidopamine; Prazosin; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Sympathectomy, Chemical; Time Factors

1983
[Effects of quinazoline-2, 4(1H, 3H)-dione compound, H-88 and pyridopyrimidine-2, 4(1H, 3H)-dione compound, HN-37 on pituitary-adrenal axis in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:8

    Topics: Adrenal Glands; Adrenalectomy; Animals; Ascorbic Acid; Circadian Rhythm; Corticosterone; Dose-Response Relationship, Drug; Edema; Hypophysectomy; Male; Organ Size; Pituitary-Adrenal System; Pyrimidinones; Quinazolines; Rats

1980
Effect of prazosin on aqueous humor dynamics in rabbits.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1980, Volume: 98, Issue:9

    Topics: Administration, Topical; Animals; Aqueous Humor; Ascorbic Acid; Blood Pressure; Intraocular Pressure; Male; Phentolamine; Prazosin; Quinazolines; Rabbits; Vitreous Body

1980
The effects of halofuginone and salinomycin, alone and in combination, on live performance and skin characteristics of female broilers: influence of a high-proline diet supplemented with ascorbic acid and zinc.
    Poultry science, 1995, Volume: 74, Issue:2

    Topics: Animals; Ascorbic Acid; Body Weight; Chickens; Coccidiostats; Female; Food, Fortified; Piperidines; Proline; Pyrans; Quinazolines; Quinazolinones; Skin; Skin Physiological Phenomena; Tensile Strength; Zinc

1995
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
    Circulation, 2002, Feb-26, Volume: 105, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Carbazoles; Cardiac Catheterization; Carvedilol; Coronary Disease; Coronary Stenosis; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Hemodynamics; Male; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Quinazolines; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Stroke Volume; Survival Rate; Thiobarbituric Acid Reactive Substances; Ventricular Function, Left; Ventricular Remodeling

2002
Inhibition of oxidative stress produced by plasma membrane NADH oxidase delays low-potassium-induced apoptosis of cerebellar granule cells.
    Journal of neurochemistry, 2002, Volume: 82, Issue:3

    Topics: Animals; Antioxidants; Apoptosis; Ascorbic Acid; Cell Membrane; Cell Survival; Cell-Free System; Cells, Cultured; Cerebellum; Cytoprotection; DNA Fragmentation; Enzyme Inhibitors; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; NADP; Neurons; Oxidative Stress; Potassium; Quinazolines; Quinazolinones; Rats; Rats, Wistar; Superoxide Dismutase

2002
Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascorbic Acid; Autophagy; Carcinoma, Squamous Cell; Caspase 3; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Gefitinib; HL-60 Cells; Humans; Methotrexate; Mitoxantrone; Mouth; Mouth Neoplasms; Phytotherapy; Plant Extracts; Quinazolines; Sodium Fluoride; Tumor Cells, Cultured

2009
Systems biology modeling reveals a possible mechanism of the tumor cell death upon oncogene inactivation in EGFR addicted cancers.
    PloS one, 2011, Volume: 6, Issue:12

    Topics: Ascorbic Acid; Cell Death; Cell Line, Tumor; Computer Simulation; Enzyme Activation; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Silencing; Humans; Models, Biological; Neoplasms; Oncogenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Reactive Oxygen Species; Reproducibility of Results; Signal Transduction; Systems Biology

2011
Vitamin C promotes maturation of T-cells.
    Antioxidants & redox signaling, 2013, Dec-10, Volume: 19, Issue:17

    Topics: Animals; Ascorbic Acid; Azepines; Cells, Cultured; Culture Media; Epigenesis, Genetic; Gene Expression; Gene Rearrangement, T-Lymphocyte; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Immunologic Factors; Methylation; Mice; Mice, Inbred C57BL; Phthalimides; Protein Processing, Post-Translational; Quinazolines; Receptors, Antigen, T-Cell; T-Lymphocytes; Tryptophan

2013
Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib.
    Anticancer research, 2018, Volume: 38, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Ascorbic Acid; Cell Survival; Cells, Cultured; Everolimus; Humans; Jurkat Cells; Leukemia; Lipid Peroxides; Lymphocytes; Organophosphates; Protein Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Vitamin K 3; Vitamins

2018
In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study.
    Molecules (Basel, Switzerland), 2020, Feb-20, Volume: 25, Issue:4

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cell Proliferation; HSP90 Heat-Shock Proteins; Humans; MCF-7 Cells; Mice; Neoplasm Proteins; Neoplasms, Experimental; Quinazolines; Xenograft Model Antitumor Assays

2020