Page last updated: 2024-08-21

quinazolines and arginine

quinazolines has been researched along with arginine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (28.57)18.2507
2000's9 (42.86)29.6817
2010's5 (23.81)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Hattori, K; Kobayashi, Y; Shimoura, K; Shinozuka, K1
Bishop, JA; Bisset, GM; Calvert, AH; Hughes, LR; Jackman, AL; Marsham, PR; O'Connor, BM; Oldfield, J; Thornton, TJ1
Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M; Peska, M1
Chen, CF; Chiou, WF; Chou, CJ; Liao, JF; Sham, AY1
Chen, CF; Chiou, WF; Liao, JF1
Changchien, L; Maley, F; Montfort, WR; Strop, P1
Andersson, K; Fujiwara, M; Persson, K1
Chen, K; Keaney, JF; Thomas, SR1
Hayakawa, H; Hirata, Y; Homma, Y; Horie, S; Kawabe, K; Kitamura, T; Minowada, S; Nagai, R; Nagata, D; Nishimatsu, H; Ohta, N; Satonaka, H; Suzuki, E; Takeuchi, T1
Haapalahti, JP; Johnson, MS; Jouppila, A; Keinänen, K; Lampinen, M; Mottershead, DG; Nyrönen, T; Pentikäinen, OT; Settimo, L1
Chattopadhyay, S; Goldman, ID; Krupenko, N; Krupenko, SA; Zhao, R1
Fukuhara, T; Inoue, A; Kimura, Y; Maemondo, M; Morikawa, N; Nukiwa, T; Saijo, Y; Suzuki, T; Watanabe, H1
Fukui, T; Furuta, K; Kunitoh, H; Matsuno, Y; Nokihara, H; Ohe, Y; Sakamoto, H; Sekine, I; Takano, T; Tamura, T; Tateishi, U; Tsuta, K; Yamamoto, N; Yoshida, T1
Lin, R; Ling, YH; Perez-Soler, R1
Hu, GY; Li, D; Li, YJ; Liu, YZ; Peng, J; Wang, L; Zhou, Y1
Jia, S; Li, S; Liu, G; Ma, L; Yu, J; Zhang, D; Zhang, S; Zheng, P1
Bouwens, EA; Burnier, L; Griffin, JH; Mosnier, LO; Sinha, RK1
Chan, KS; Lim, KH; Lim, WT; Lynette, O; Montoya, J; Ng, QS; Sakktee Krisna, S; Takano, A; Tan, DS; Tan, EH1
Geng, D; Sun, D; Zhang, L; Zhang, W1
Alessandri, B; Jussen, D; Kempski, O; Krämer, TJ; Krenzlin, H; Sakas, W1
Chen, F; Liao, J; Lu, Q; Niu, C; Wang, H; Wang, S; Yu, Y1

Trials

1 trial(s) available for quinazolines and arginine

ArticleYear
Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jul-20, Volume: 24, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Antineoplastic Agents; Arginine; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; Feasibility Studies; Female; Gefitinib; Glutamic Acid; Humans; Leucine; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Staging; Positron-Emission Tomography; Prospective Studies; Quinazolines; Treatment Outcome

2006

Other Studies

20 other study(ies) available for quinazolines and arginine

ArticleYear
Role of nitric oxide from the endothelium on the neurogenic contractile responses of rabbit pulmonary artery.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Electric Stimulation; Electrochemistry; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Pulmonary Artery; Quinazolines; Rabbits; Sympathetic Nervous System; Tetrodotoxin

1992
Quinazoline antifolate thymidylate synthase inhibitors: benzoyl ring modifications in the C2-methyl series.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:11

    Topics: Animals; Antineoplastic Agents; Arginine; Cell Division; Folic Acid Antagonists; Leukemia L1210; Mice; Molecular Structure; Quinazolines; Structure-Activity Relationship; Thymidylate Synthase

1990
Arginine and ornithine metabolizing enzymes in testosterone-induced hypertrophic mouse kidney.
    The international journal of biochemistry & cell biology, 1995, Volume: 27, Issue:3

    Topics: Animals; Arginase; Arginine; Eflornithine; Enzyme Induction; Female; Folic Acid; Hypertrophy; Kidney; Male; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Putrescine; Quinazolines; Sex Factors; Testosterone

1995
The mechanism of the vasodilator effect of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa.
    European journal of pharmacology, 1994, May-12, Volume: 257, Issue:1-2

    Topics: Acetylcholine; Alkaloids; Animals; Arginine; Atropine; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indole Alkaloids; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Phenylephrine; Quinazolines; Rats; Rats, Sprague-Dawley; Triprolidine; Vasodilation; Yohimbine

1994
Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa.
    Journal of natural products, 1996, Volume: 59, Issue:4

    Topics: Alkaloids; Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Enzyme Inhibitors; In Vitro Techniques; Indole Alkaloids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Vasodilator Agents

1996
Crystal structures of a marginally active thymidylate synthase mutant, Arg 126-->Glu.
    Protein science : a publication of the Protein Society, 1997, Volume: 6, Issue:12

    Topics: Antineoplastic Agents; Arginine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyuracil Nucleotides; Dimerization; Folic Acid; Folic Acid Antagonists; Glutamic Acid; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Structure; Mutation; Phosphates; Quinazolines; Thymidylate Synthase

1997
Nitric oxide-induced cGMP accumulation in the mouse bladder is not related to smooth muscle relaxation.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: Animals; Arginine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phosphodiesterase Inhibitors; Piperazines; Piperidines; Purines; Quinazolines; Sildenafil Citrate; Sulfones; Urethra; Urinary Bladder

2000
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.
    The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8

    Topics: Animals; Aorta; Arginine; Calcium Signaling; Cells, Cultured; Chromones; Citrulline; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Morpholines; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Quinazolines; Signal Transduction; Swine; Tyrphostins

2002
Effects of intracavernous administration of adrenomedullin on erectile function in rats.
    Peptides, 2001, Volume: 22, Issue:11

    Topics: Adrenomedullin; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Erectile Dysfunction; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Peptides; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Rats; Rats, Wistar

2001
Determinants of antagonist binding at the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit, GluR-D. Role of the conserved arginine 507 and glutamate 727 residues.
    European journal of biochemistry, 2002, Volume: 269, Issue:24

    Topics: Animals; Arginine; Binding Sites; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Glutamic Acid; Imidazoles; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quinazolines; Rats; Receptors, Glutamate

2002
The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:2

    Topics: Amino Acid Substitution; Antineoplastic Agents; Arginine; Carrier Proteins; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Glutamates; Glycine; Guanine; Humans; Leucovorin; Methotrexate; Mutation; Pemetrexed; Phosphoribosylglycinamide Formyltransferase; Purines; Pyrimidines; Quinazolines; Receptors, Cell Surface; Thiophenes; Thymidylate Synthase

2006
Epidermal growth factor receptor mutation detection using high-resolution melting analysis predicts outcomes in patients with advanced non small cell lung cancer treated with gefitinib.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Sep-15, Volume: 13, Issue:18 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Antineoplastic Agents; Arginine; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; DNA Mutational Analysis; ErbB Receptors; Female; Gefitinib; Humans; Leucine; Lung Neoplasms; Male; Middle Aged; Mutation; Prognosis; Quinazolines; Survival Analysis; Treatment Outcome

2007
Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Molecular pharmacology, 2008, Volume: 74, Issue:3

    Topics: Amino Acid Substitution; Apoptosis; Arginine; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Cell Line, Tumor; Down-Regulation; Drug Screening Assays, Antitumor; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Humans; Leucine; Lung Neoplasms; Mitochondria; Mutation; Oxidative Phosphorylation; Protein Structure, Quaternary; Protein Transport; Quinazolines; Reactive Oxygen Species; RNA, Small Interfering

2008
Reduction of asymmetric dimethylarginine in the protective effects of rutaecarpine on gastric mucosal injury.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:10

    Topics: Amidohydrolases; Animals; Anti-Ulcer Agents; Arginine; Calcitonin Gene-Related Peptide; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Indicators and Reagents; Indole Alkaloids; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protective Agents; Quinazolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer

2008
Expression and regulation of amphiregulin in Gsα-mutated human bone marrow stromal cells of fibrous dysplasia of mandible.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:5

    Topics: Adolescent; Amino Acid Substitution; Amphiregulin; Arginine; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Coloring Agents; DNA Mutational Analysis; EGF Family of Proteins; Enzyme Inhibitors; ErbB Receptors; Female; Fibrous Dysplasia of Bone; Glycoproteins; GTP-Binding Protein alpha Subunits, Gs; Humans; Intercellular Signaling Peptides and Proteins; Mandibular Diseases; Mutation, Missense; Osteoblasts; Polymorphism, Restriction Fragment Length; Quinazolines; Signal Transduction; Stromal Cells; Tetrazolium Salts; Tyrphostins

2011
Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46.
    Blood, 2012, Dec-20, Volume: 120, Issue:26

    Topics: Animals; Arginine; Capillary Permeability; Catalytic Domain; Cells, Cultured; Drug Agonism; Endothelium, Vascular; HEK293 Cells; Humans; Mice; Models, Biological; Models, Molecular; Protein C; Proteolysis; Pyrroles; Quinazolines; Receptor, PAR-1

2012
Molecular profiling for druggable genetic abnormalities in carcinoma of unknown primary.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, May-10, Volume: 31, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arginine; Biopsy; Carboplatin; Carcinoma; Deoxycytidine; Disease-Free Survival; ErbB Receptors; Gefitinib; Gemcitabine; Humans; Immunohistochemistry; Leucine; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Staging; Neoplasms, Unknown Primary; Point Mutation; Quinazolines; Tomography, X-Ray Computed

2013
The therapy of gefitinib towards breast cancer partially through reversing breast cancer biomarker arginine.
    African health sciences, 2015, Volume: 15, Issue:2

    Topics: Adult; Antineoplastic Agents; Area Under Curve; Arginine; Breast Neoplasms; Case-Control Studies; Female; Gefitinib; Humans; Mass Spectrometry; Metabolomics; Predictive Value of Tests; Quinazolines; ROC Curve; Sensitivity and Specificity

2015
Thrombin contributes to the injury development and neurological deficit after acute subdural hemorrhage in rats only in collaboration with additional blood-derived factors.
    BMC neuroscience, 2018, Dec-27, Volume: 19, Issue:1

    Topics: Animals; Arginine; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hematoma, Subdural, Acute; Male; Motor Skills; Pipecolic Acids; Protein Serine-Threonine Kinases; Pyrroles; Quinazolines; Random Allocation; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Thrombin

2018
Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats.
    Food & function, 2022, Jun-20, Volume: 13, Issue:12

    Topics: Amino Sugars; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Metabolomics; Nucleotides; Proline; Quinazolines; Rats; Streptozocin; Tryptophan

2022