Page last updated: 2024-08-21

quinazolines and aniline

quinazolines has been researched along with aniline in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's10 (66.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
App, H; Chen, I; Chen, J; Gazit, A; Hirth, P; Levitzki, A; McMahon, G1
Ballard, P; Barlaam, BC; Bradbury, RH; Dishington, A; Hennequin, LF; Hickinson, DM; Hollingsworth, IM; Kettle, JG; Klinowska, T; Ogilvie, DJ; Pearson, SE; Scott, JS; Suleman, A; Whittaker, R; Williams, EJ; Wood, R; Wright, L1
Chandrasekara Reddy, G; Chandregowda, V; Kush, AK1
Azas, N; Dumètre, A; Gellis, A; Hutter, S; Kabri, Y; Laget, M; Vanelle, P; Verhaeghe, P1
Fujii, N; Ohno, H; Ohta, Y; Oishi, S; Tokimizu, Y1
Ge, ZM; Li, QY; Li, RD; Li, RT; Zhang, X1
Brdar, I; Deng, X; Faessler, R; Mani, NS; Roessler, A; Sales, ZS; Wu, J1
Hauf, S; Koch, A; Rauh, D; Richters, A; Rode, HB1
Feng, C; Wang, Z; Yan, Y; Zha, Z; Zhang, Y1
Kumar, M; Kumar, N; Kumar, V; Sharma, S1
Cheng, W; Hu, Y; Peng, P; Qiu, N; Sheng, R; Yuan, Y1
Cimarelli, C; Di Nicola, M; Diomedi, S; Giovannini, R; Hamprecht, D; Marcantoni, E; Properzi, R; Sorana, F1
Liu, K; Ma, X; Shu, X; Sun, Y; Wang, C; Wang, Q; Wu, B; Zhen, Y; Zhou, Y; Zhu, X1
An, L; Gao, CY; Li, CL; Liu, Y; Meng, L; Wu, XQ; Xu, L; Zhang, L; Zhang, WQ; Zheng, YG1
Abdel-Rahman, HM; Amin, NH; Elsaadi, MT; Zaki, SS1

Other Studies

15 other study(ies) available for quinazolines and aniline

ArticleYear
Tyrphostins IV--highly potent inhibitors of EGF receptor kinase. Structure-activity relationship study of 4-anilidoquinazolines.
    Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:8

    Topics: Aniline Compounds; ErbB Receptors; Phosphorylation; Protein Kinase C; Quinazolines; Staurosporine; Structure-Activity Relationship

1996
Neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase.
    Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22

    Topics: Administration, Oral; Aniline Compounds; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Dogs; Drug Synergism; Mice; Molecular Structure; Neoplasms; Quinazolines; Rats; Receptor, ErbB-2; Triazoles; Xenograft Model Antitumor Assays

2007
Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; ErbB Receptors; Gefitinib; Humans; Models, Molecular; Neoplasms; Phosphotransferases; Protein Structure, Tertiary; Quinazolines

2009
Original quinazoline derivatives displaying antiplasmodial properties.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:2

    Topics: Aniline Compounds; Animals; Antiprotozoal Agents; Cell Line; Drug Design; Humans; Inhibitory Concentration 50; Leishmania donovani; Phosphotransferases; Plasmodium falciparum; Quinazolines; Toxoplasma

2010
Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines.
    Organic letters, 2010, Sep-03, Volume: 12, Issue:17

    Topics: Aniline Compounds; Benzamidines; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Molecular Structure; Quinazolines

2010
Novel EGFR inhibitors prepared by combination of dithiocarbamic acid esters and 4-anilinoquinazolines.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Esters; Humans; Molecular Structure; Quinazolines; Structure-Activity Relationship; Thiocarbamates

2011
Direct, metal-free amination of heterocyclic amides/ureas with NH-heterocycles and N-substituted anilines in POCl3.
    The Journal of organic chemistry, 2011, Oct-21, Volume: 76, Issue:20

    Topics: Amides; Amination; Aniline Compounds; Anticholesteremic Agents; Azabicyclo Compounds; Benzamides; Catalysis; Chemistry, Pharmaceutical; Erlotinib Hydrochloride; Eszopiclone; Fluorobenzenes; Heterocyclic Compounds; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Hypoglycemic Agents; Imatinib Mesylate; Molecular Structure; Phosphorus Compounds; Piperazines; Prescription Drugs; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Rosiglitazone; Rosuvastatin Calcium; Sulfonamides; Thiazolidinediones; Urea

2011
A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase.
    ACS chemical biology, 2012, Apr-20, Volume: 7, Issue:4

    Topics: Aniline Compounds; Aurora Kinases; Drug Design; Genetic Engineering; Molecular Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines; Schizosaccharomyces

2012
Selective iodine-catalyzed intermolecular oxidative amination of C(sp3)-H bonds with ortho-carbonyl-substituted anilines to give quinazolines.
    Angewandte Chemie (International ed. in English), 2012, Aug-06, Volume: 51, Issue:32

    Topics: Amination; Aniline Compounds; Catalysis; Hydrogen Bonding; Iodine; Molecular Structure; Oxidation-Reduction; Quinazolines

2012
Metal-free transfer hydrogenation of nitroarenes in water with vasicine: revelation of organocatalytic facet of an abundant alkaloid.
    The Journal of organic chemistry, 2014, Oct-03, Volume: 79, Issue:19

    Topics: Alkaloids; Aniline Compounds; Catalysis; Chemical Phenomena; Hydrogenation; Justicia; Metals; Nitro Compounds; Plant Leaves; Quinazolines; Water

2014
Identification of novel 4-anilinoquinazoline derivatives as potent EGFR inhibitors both under normoxia and hypoxia.
    Bioorganic & medicinal chemistry, 2014, Dec-15, Volume: 22, Issue:24

    Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; HT29 Cells; Humans; Molecular Docking Simulation; NADP; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Quinazolines; Structure-Activity Relationship

2014
An efficient one-pot two catalyst system in the construction of 2-substituted benzimidazoles: synthesis of benzimidazo[1,2-c]quinazolines.
    Organic & biomolecular chemistry, 2015, Dec-28, Volume: 13, Issue:48

    Topics: Aniline Compounds; Benzimidazoles; Catalysis; Chemistry Techniques, Analytical; Molecular Structure; Quinazolines; Schiff Bases

2015
Novel Quinazoline Derivatives Bearing Various 4-Aniline Moieties as Potent EGFR Inhibitors with Enhanced Activity Against NSCLC Cell Lines.
    Chemical biology & drug design, 2016, Volume: 87, Issue:4

    Topics: Aniline Compounds; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Quinazolines; Spectrometry, Mass, Electrospray Ionization

2016
Design, synthesis and biological evaluation of 4-aniline quinazoline derivatives conjugated with hydrogen sulfide (H
    European journal of medicinal chemistry, 2020, Sep-15, Volume: 202

    Topics: Aniline Compounds; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Hydrogen Sulfide; Molecular Structure; Mutation; Protein Kinase Inhibitors; Quinazolines; Structure-Activity Relationship

2020
Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers.
    Bioorganic chemistry, 2020, Volume: 105

    Topics: A549 Cells; Aniline Compounds; Antineoplastic Agents; Apoptosis; Benzenesulfonamides; Caspase 3; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Sulfonamides

2020