quinazolines has been researched along with ag-490 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (81.82) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L; Shaw, PE | 1 |
| Arbel, R; Ben-Bassat, H; Hartzstark, Z; Klein, BY; Laufer, N; Levitzki, R; Rojansky, N | 1 |
| Dowlati, A; Kern, JA; Nethery, D | 1 |
| Briones, J; Ferrer, B; Forné, I; Juarez, C; Martinez-Gallo, M; Martinez-Lostao, L; Rodriguez-Sanchez, JL; Sierra, J | 1 |
| Cochet, O; Frelin, C; Imbert, V; Peyron, JF | 1 |
| Halgunset, J; Larsson, E; Skogseth, H | 1 |
| Arany, I; Megyesi, JK; Nelkin, BD; Safirstein, RL | 1 |
| Kankaanranta, H; Kärpänniemi, O; Korhonen, R; Moilanen, E; Nieminen, R; Sareila, O | 1 |
| Andina, N; Dahinden, CA; Didichenko, S; Schmidt-Mende, J; Simon, HU | 1 |
| Baik, EJ; Chung, JI; Jung, YS; Kim, YH; Lee, SH; Moon, CH; Suh-Kim, H; Woo, HG | 1 |
| Cai, X; Cao, P; Hu, C; Lu, W; Xu, X; Yang, J; Yu, Q | 1 |
11 other study(ies) available for quinazolines and ag-490
| Article | Year |
|---|---|
Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines.
Topics: Breast Neoplasms; Cell Division; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Female; Humans; Oncogene Proteins v-erbB; Phosphorylation; Quinazolines; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2002 |
Inhibitors that target protein kinases for the treatment of ovarian carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Catechols; Cell Cycle; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Nitriles; Ovarian Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Time Factors; Tumor Cells, Cultured; Tyrphostins | 2003 |
Combined inhibition of epidermal growth factor receptor and JAK/STAT pathways results in greater growth inhibition in vitro than single agent therapy.
Topics: Antibodies, Monoclonal; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Inhibitory Concentration 50; Phosphorylation; Quinazolines; Receptor, ErbB-2; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Tyrphostins | 2004 |
Role of the STAT1 pathway in apoptosis induced by fludarabine and JAK kinase inhibitors in B-cell chronic lymphocytic leukemia.
Topics: Aged; Aged, 80 and over; Apoptosis; Cell Survival; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Female; Flow Cytometry; Humans; Interferon-gamma; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; STAT1 Transcription Factor; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tyrphostins; Vidarabine | 2005 |
Constitutive activation of STAT proteins in the HDLM-2 and L540 Hodgkin lymphoma-derived cell lines supports cell survival.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Electrophoretic Mobility Shift Assay; Hodgkin Disease; Humans; Immunoprecipitation; Quinazolines; RNA, Small Interfering; Signal Transduction; STAT Transcription Factors; Tumor Cells, Cultured; Tyrphostins | 2006 |
Inhibitors of tyrosine kinase inhibit the production of urokinase plasminogen activator in human prostatic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Genistein; Humans; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Tumor Cells, Cultured; Tyrphostins; Urokinase-Type Plasminogen Activator | 2005 |
STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells.
Topics: Animals; Cell Line; Cell Survival; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Hydrogen Peroxide; Janus Kinase 2; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Quinazolines; Signal Transduction; STAT3 Transcription Factor; Tyrosine; Tyrphostins | 2006 |
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages.
Topics: Animals; Blotting, Western; Cell Nucleus; Enzyme Inhibitors; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Janus Kinase 1; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Polymerase Chain Reaction; Quinazolines; Tyrphostins | 2006 |
Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils.
Topics: Adenine; Androstadienes; Apoptosis; Cells, Cultured; Chromones; Eosinophils; Humans; Hypersensitivity; Interleukin-5; Janus Kinase 2; Microscopy, Confocal; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-pim-1; Quinazolines; Tyrphostins; Wortmannin; Xanthenes | 2009 |
Differential regulation of proliferation and differentiation in neural precursor cells by the Jak pathway.
Topics: Animals; Blotting, Western; Brain; Cell Differentiation; Cell Proliferation; Cells, Cultured; Immunohistochemistry; Janus Kinase 2; Janus Kinase 3; Mice; Neurogenesis; Neurons; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stem Cells; Tyrphostins | 2010 |
Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Interleukin-6; Janus Kinase 2; Liver Neoplasms; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Quinazolines; RNA Interference; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Tyrphostins; Xenograft Model Antitumor Assays | 2013 |