Page last updated: 2024-08-21

quinazolines and ag 1879

quinazolines has been researched along with ag 1879 in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's27 (75.00)29.6817
2010's9 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berk, BC; Chen, K; Keaney, JF; Vita, JA1
Barrett, KE; McCole, DF; Uribe, JM1
Li, J; Majumdar, AP; Xiao, ZQ1
Arbel, R; Ben-Bassat, H; Hartzstark, Z; Klein, BY; Laufer, N; Levitzki, R; Rojansky, N1
Bader, B; Glienke, J; Sturz, A; Thierauch, KH1
Slomiany, A; Slomiany, BL2
Anaganti, S; Billaud, M; Carlomagno, F; Fusco, A; Guida, T; Ryan, AJ; Santoro, M; Vecchio, G1
Baumgarten, CM; Ren, Z1
Delamere, NA; Tamiya, S1
Bigner, DD; Kwatra, MM; Richardson, MD; Yamaguchi, K1
Churg, A; Vincent, R; Wang, RD; Wang, X; Xie, C1
Ali, N; Fujita, Y; Ishizawa, K; Izawa, Y; Kanematsu, Y; Ohnishi, H; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Kim, SY; Kim, YK; Kwon, CH; Lee, JS1
Cai, K; Enomoto, A; Hosoi, Y; Li, Z; Matsumoto, Y; Miyagawa, K; Morita, A; Nakagawa, K; Tanno, Y1
Alagarsamy, S; Alexander, LD; Cui, XL; Ding, Y; Douglas, JG1
Boron, WF; Bouyer, P; Zhou, Y1
Azar, ZM; Mehdi, MZ; Srivastava, AK1
Ascoli, M; Shiraishi, K1
Abel, J; Cline, JE; Fritsche, E; Moors, M1
Botta, M; Manetti, F; Schenone, S1
Chen, YR; Cheng, HH; Fu, YN; Huang, SF; Tsai, SF; Yang, CH; Yeh, CL1
Bhattacharya, S; Johnson, LR; Ray, RM1
Cruz-Rangel, S; Islas, LD; Lezama, RA; Pasantes-Morales, H; Ramos-Mandujano, G; Vázquez-Juárez, E1
Cheon, H; Cho, S; Kim, HJ; Kim, HS; Lee, JY; Sohn, J; Won, NH; Woo, YS1
Linsdell, P; McDonald, TF; Missan, S1
Choi, WS; Han, JW; Jeong, KJ; Kang, JK; Kim, YK; Lee, HY; Lee, KB; Park, CG; Park, SY; Seo, JH1
Bareford, MD; Cruickshanks, N; Dai, Y; Dent, P; Grant, S; Hamed, HA; Hubbard, N; Mitchell, C; Tang, Y; Tye, G; Yacoub, A1
Blanco, G; Jansson, K; Nguyen, AN; Reif, GA; Sánchez, G; Sharma, M; Wallace, DP1
Adès, L; Boehrer, S; Bouteloup, C; de Botton, S; Fenaux, P; Galluzzi, L; Gardin, C; Harper, F; Kroemer, G; Lainey, E; Pierron, G; Sébert, M; Tailler, M; Thépot, S1
Cicha, I; Daniel, WG; Garlichs, CD; Urschel, K1
Chen, SY; Hsu, HC; Huang, CY; Tang, CH; Tsai, HC1
Jeong, YJ; Kim, CH; Kim, DJ; Kim, JC; Lee, KB; Oh, SM; Park, JH1
Liu, Y; Wang, Y; Wu, W; Xu, Y; Zhang, H1
Jensen, RT; Moody, TW; Moreno, P; Nuche-Berenguer, B1
Ciotkowska, A; Gratzke, C; Hennenberg, M; Herlemann, A; Janich, S; Liu, C; Rutz, B; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R; Wang, Y1

Reviews

1 review(s) available for quinazolines and ag 1879

ArticleYear
SRC inhibitors and angiogenesis.
    Current pharmaceutical design, 2007, Volume: 13, Issue:21

    Topics: Angiogenesis Inhibitors; Animals; Humans; Neoplasms; Neovascularization, Physiologic; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Quinazolines; src-Family Kinases; Structure-Activity Relationship

2007

Other Studies

35 other study(ies) available for quinazolines and ag 1879

ArticleYear
c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
    The Journal of biological chemistry, 2001, May-11, Volume: 276, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aorta; Benzoquinones; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Genistein; GRB2 Adaptor Protein; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Pyrimidines; Quinazolines; Quinones; Rifabutin; Swine; Transcriptional Activation; Tyrphostins

2001
Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:4

    Topics: Antibodies; Blotting, Western; Carbachol; Cell Line; Cell Membrane; Chlorides; Colon; Enzyme Inhibitors; ErbB Receptors; Humans; Immunosorbent Techniques; Interferon-gamma; Intestinal Mucosa; Kinetics; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Transforming Growth Factor alpha; Tyrphostins

2002
Regulation of TGF-alpha-induced activation of AP-1 in the aging gastric mucosa.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:2

    Topics: Aging; Animals; DNA; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Gastric Mucosa; Male; Mitogen-Activated Protein Kinase Kinases; Pyrimidines; Quinazolines; Rats; Rats, Inbred F344; Signal Transduction; src-Family Kinases; Transcription Factor AP-1; Transforming Growth Factor alpha

2003
Inhibitors that target protein kinases for the treatment of ovarian carcinoma.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Catechols; Cell Cycle; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Nitriles; Ovarian Neoplasms; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Time Factors; Tumor Cells, Cultured; Tyrphostins

2003
EphB4 signaling is capable of mediating ephrinB2-induced inhibition of cell migration.
    Biochemical and biophysical research communications, 2004, Jan-02, Volume: 313, Issue:1

    Topics: Animals; Cell Movement; Cells, Cultured; CHO Cells; Cricetinae; Endothelium, Vascular; Enzyme Inhibitors; Ephrin-B2; ErbB Receptors; Humans; Microcirculation; Phosphorylation; Pyrimidines; Quinazolines; Receptor Protein-Tyrosine Kinases; Receptor, EphB4; Recombinant Proteins; Signal Transduction; src-Family Kinases; Vascular Endothelial Growth Factors

2004
Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation.
    Biochemical and biophysical research communications, 2004, May-21, Volume: 318, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Androstadienes; Animals; Bucladesine; Choline; Colforsin; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Isoproterenol; Phosphoinositide-3 Kinase Inhibitors; Phospholipids; Pyrimidines; Quinazolines; Rats; Receptors, Adrenergic, beta; Saliva; src-Family Kinases; Sublingual Gland; Transcriptional Activation; Wortmannin

2004
Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors.
    Oncogene, 2004, Aug-12, Volume: 23, Issue:36

    Topics: Carcinoma, Medullary; Catalytic Domain; Cell Line; Drug Resistance; Enzyme Inhibitors; Mitogens; Piperidines; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Pyrazoles; Pyrimidines; Quinazolines; Receptor Protein-Tyrosine Kinases; Signal Transduction; Thyroid Neoplasms; Valine

2004
Antagonistic regulation of swelling-activated Cl- current in rabbit ventricle by Src and EGFR protein tyrosine kinases.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6

    Topics: Animals; Cadmium; Chloride Channels; Enzyme Inhibitors; ErbB Receptors; Genistein; Heart Ventricles; Membrane Potentials; Pyrimidines; Quinazolines; Rabbits; src-Family Kinases; Tamoxifen; Ventricular Function

2005
Porphyromonas gingivalis lipopolysaccharide-induced up-regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation.
    IUBMB life, 2004, Volume: 56, Issue:10

    Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; ErbB Receptors; Lipopolysaccharides; Mucins; Oligopeptides; Porphyromonas gingivalis; Pyrimidines; Quinazolines; Rats; Saliva; Salivary Glands; src-Family Kinases; Time Factors; Transcriptional Activation; Trypan Blue; Up-Regulation

2004
Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:6

    Topics: Animals; Blotting, Western; Cell Proliferation; Enzyme Inhibitors; Epithelium; Lens, Crystalline; Organ Culture Techniques; Phosphorylation; Phosphotyrosine; Proliferating Cell Nuclear Antigen; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Swine; Tyrosine; Tyrphostins

2005
Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:6

    Topics: Acetophenones; Benzopyrans; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Intracellular Signaling Peptides and Proteins; Oligonucleotides, Antisense; Phosphorylation; Protein Kinase C-delta; Pyrimidines; Quinazolines; Receptors, Neurokinin-1; RNA, Small Interfering; Signal Transduction; Tyrphostins

2005
Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.
    Toxicology and applied pharmacology, 2005, Oct-01, Volume: 208, Issue:1

    Topics: Air Pollutants; Animals; Binding, Competitive; Biological Transport; Deferoxamine; Dust; Epithelial Cells; Ferric Compounds; Free Radical Scavengers; In Vitro Techniques; NF-kappa B; Particle Size; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiourea; Time Factors; Titanium; Trachea; Tyrphostins

2005
Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation.
    Endocrinology, 2006, Volume: 147, Issue:3

    Topics: Atherosclerosis; Benzoquinones; Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Cells, Cultured; Cinnamates; CSK Tyrosine-Protein Kinase; Disease Progression; Endothelial Cells; Endothelium, Vascular; Humans; Immunoblotting; Immunoprecipitation; Lactams, Macrocyclic; Ligands; Lysophosphatidylcholines; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Quinones; Rifabutin; src-Family Kinases; Transcriptional Activation; Transfection; Vascular Endothelial Growth Factor Receptor-2

2006
EGFR-dependent ERK activation triggers hydrogen peroxide-induced apoptosis in OK renal epithelial cells.
    Archives of toxicology, 2006, Volume: 80, Issue:6

    Topics: Animals; Apoptosis; Butadienes; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hydrogen Peroxide; Kidney Tubules, Proximal; MAP Kinase Kinase 1; Membrane Potentials; Mitochondrial Membranes; Nitriles; Opossums; Oxidants; Pyrimidines; Quinazolines; Transfection; Tyrphostins

2006
Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.
    Biochemical and biophysical research communications, 2006, Mar-10, Volume: 341, Issue:2

    Topics: Androstadienes; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Radiation; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanosine Triphosphate; Humans; Immunoblotting; Immunoprecipitation; Infrared Rays; Intracellular Signaling Peptides and Proteins; Kinetics; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; Radiation, Ionizing; Signal Transduction; src-Family Kinases; Temperature; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Wortmannin; X-Rays

2006
Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptor.
    Kidney international, 2006, Volume: 69, Issue:10

    Topics: Angiotensin II; Animals; Arachidonic Acid; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Glutathione Transferase; Kidney Tubules, Proximal; Kinetics; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Quinazolines; Rabbits; Recombinant Fusion Proteins; Transcriptional Activation; Tyrphostins

2006
Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules.
    American journal of physiology. Renal physiology, 2006, Volume: 291, Issue:2

    Topics: Absorption; Animals; Bicarbonates; Carbon Dioxide; Dimethyl Sulfoxide; Enzyme Inhibitors; Female; Genistein; Imidazoles; Kidney Tubules, Proximal; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Rabbits; Receptor Protein-Tyrosine Kinases; Receptors, Cell Surface; Signal Transduction

2006
Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:7

    Topics: Animals; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Focal Adhesion Kinase 2; Hydrogen Peroxide; Immunoblotting; Insulin-Like Growth Factor I; Models, Biological; Muscle, Smooth, Vascular; Oxidants; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Quinazolines; Receptor, IGF Type 1; src-Family Kinases; Tyrosine; Tyrphostins

2006
Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.
    Endocrinology, 2007, Volume: 148, Issue:7

    Topics: Animals; Blotting, Western; Butadienes; Cell Proliferation; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP; Dipeptides; Epidermal Growth Factor; Flavonoids; Immunohistochemistry; Inositol Phosphates; Leydig Cells; Luteinizing Hormone; Male; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Pyrazoles; Pyrimidines; Quinazolines; Rats; Recombinant Proteins; Signal Transduction; Steroids; Tyrphostins

2007
ERK-dependent and -independent pathways trigger human neural progenitor cell migration.
    Toxicology and applied pharmacology, 2007, May-15, Volume: 221, Issue:1

    Topics: Astrocytes; Blotting, Western; Cell Differentiation; Cell Movement; Cell Survival; Cells, Cultured; Flavonoids; Humans; Indoles; Maleimides; Methylmercury Compounds; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Protein Kinase C; Pyrimidines; Quinazolines; Signal Transduction; Spheroids, Cellular; src-Family Kinases; Stem Cells; Sulfonamides; Tetradecanoylphorbol Acetate; Tyrphostins

2007
EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.
    Oncogene, 2008, Feb-07, Volume: 27, Issue:7

    Topics: Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Gefitinib; Humans; Immunoprecipitation; Lung Neoplasms; Phosphorylation; Point Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Quinazolines; Sequence Deletion; Tyrosine

2008
EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells.
    Cellular signalling, 2007, Volume: 19, Issue:12

    Topics: Animals; Apoptosis; Cell Survival; Cycloheximide; Eflornithine; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibronectins; Integrin beta3; Intestinal Mucosa; MAP Kinase Kinase Kinases; Mice; Mutation; Oligopeptides; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Protein Kinase Inhibitors; Putrescine; Pyrimidines; Quinazolines; Rats; Signal Transduction; src-Family Kinases; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

2007
Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 455, Issue:5

    Topics: Animals; Calcium; Cell Size; Chloride Channels; Chlorides; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Estrenes; Hemostatics; Mice; Osmotic Pressure; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pyrimidines; Pyrrolidinones; Quinazolines; Signal Transduction; src-Family Kinases; Swiss 3T3 Cells; Taurine; Thrombin; Tritium; Tyrphostins

2008
Signaling pathway for 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages.
    Experimental & molecular medicine, 2007, Aug-31, Volume: 39, Issue:4

    Topics: Animals; Benzoflavones; Cell Differentiation; Cell Line, Tumor; Enzyme Activation; ErbB Receptors; Genistein; Hazardous Substances; Humans; Macrophages; MAP Kinase Signaling System; Mice; Phosphorylation; Polychlorinated Dibenzodioxins; Pyrimidines; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; src-Family Kinases; Tumor Necrosis Factor-alpha

2007
Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 456, Issue:3

    Topics: Action Potentials; Animals; Cell Size; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; ErbB Receptors; Genistein; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Kinetics; Myocytes, Cardiac; Osmotic Pressure; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Signal Transduction; src-Family Kinases; Tyrphostins; Vanadates

2008
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
    Experimental & molecular medicine, 2008, Dec-31, Volume: 40, Issue:6

    Topics: Butadienes; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Cyclooxygenase 2; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Lysophospholipids; Nitriles; Ovarian Neoplasms; Pertussis Toxin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrimidines; Quinazolines; Receptors, Lysophosphatidic Acid; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins

2008
Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death.
    Cancer biology & therapy, 2011, Aug-01, Volume: 12, Issue:3

    Topics: Animals; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Benzimidazoles; Benzodioxoles; Breast Neoplasms; Cell Death; Cell Line, Transformed; Cell Transformation, Neoplastic; Checkpoint Kinase 1; Dasatinib; Female; Fibroblasts; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Protease Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Pyrimidines; Quinazolines; Radiation Tolerance; src-Family Kinases; Thiazoles

2011
Ouabain activates the Na-K-ATPase signalosome to induce autosomal dominant polycystic kidney disease cell proliferation.
    American journal of physiology. Renal physiology, 2011, Volume: 301, Issue:4

    Topics: beta-Cyclodextrins; Caveolin 1; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; ErbB Receptors; Humans; MAP Kinase Kinase Kinases; Ouabain; Phosphorylation; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-fyn; Pyrimidines; Quinazolines; Signal Transduction; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Tyrphostins

2011
Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.
    Cell cycle (Georgetown, Tex.), 2011, Sep-15, Volume: 10, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Biomarkers, Tumor; Enzyme Activation; Erlotinib Hydrochloride; Flow Cytometry; G1 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Microscopy, Electron; Microscopy, Fluorescence; Microtubule-Associated Proteins; Phosphorylation; Pyrimidines; Quinazolines; Signal Transduction; Sirolimus; src-Family Kinases; Stilbenes; TOR Serine-Threonine Kinases

2011
VEGFR2 signalling contributes to increased endothelial susceptibility to TNF-α under chronic non-uniform shear stress.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Active Transport, Cell Nucleus; Blotting, Western; Cell Adhesion; Cells, Cultured; Chromones; Coculture Techniques; Dose-Response Relationship, Drug; E-Selectin; Fluorescent Antibody Technique; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Mechanotransduction, Cellular; Monocytes; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; RNA Interference; src-Family Kinases; Stress, Mechanical; Transfection; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor Receptor-2

2011
Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:10

    Topics: Acetophenones; Adult; Amino Acid Chloromethyl Ketones; Benzopyrans; Chemokine CCL2; Enzyme Inhibitors; ErbB Receptors; Humans; Middle Aged; Osteoblasts; Protein Kinase C; Pyrimidines; Quinazolines; Receptor, PAR-1; Signal Transduction; src-Family Kinases; Thrombin; Transcriptional Activation; Tyrphostins

2012
RIP2/RICK-dependent cytokine production upon Yersinia enterocolitica infection in macrophages with TLR4 deficiency.
    Scandinavian journal of immunology, 2013, Volume: 78, Issue:5

    Topics: Animals; Enzyme Inhibitors; Gefitinib; Imidazoles; Interleukin-10; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Quinazolines; Receptor-Interacting Protein Serine-Threonine Kinase 2; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Yersinia enterocolitica; Yersinia Infections

2013
Dysregulated activation of c-Src in gestational trophoblastic disease contributes to its aggressive progression.
    Placenta, 2014, Volume: 35, Issue:10

    Topics: Benzodioxoles; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chorionic Gonadotropin; Enzyme Inhibitors; Female; Gestational Trophoblastic Disease; Humans; Pregnancy; Pyrimidines; Quinazolines; src-Family Kinases

2014
CI-988 Inhibits EGFR Transactivation and Proliferation Caused by Addition of CCK/Gastrin to Lung Cancer Cells.
    Journal of molecular neuroscience : MN, 2015, Volume: 56, Issue:3

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dipeptides; ErbB Receptors; Gastrins; Gefitinib; Hormone Antagonists; Humans; Indoles; Lung Neoplasms; Meglumine; Pyrimidines; Quinazolines

2015
Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2.
    British journal of pharmacology, 2016, Volume: 173, Issue:23

    Topics: Blotting, Western; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Prostate; Prostatic Hyperplasia; Pyrimidines; Quinazolines; Real-Time Polymerase Chain Reaction; src-Family Kinases; Stromal Cells

2016