Page last updated: 2024-08-21

quinazolines and acridines

quinazolines has been researched along with acridines in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.00)18.7374
1990's3 (10.00)18.2507
2000's11 (36.67)29.6817
2010's9 (30.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Michael, JP11
Grundon, MF3
Elslager, EF1
Gröger, D1
Elslager, EF; Haley, NF; McLean, JR; Potoczak, D; Veloso, H; Wheelock, RH1
Bernhardt, G; Buschauer, A; Gartner, M; Giannis, A; Gross, D; Müller, C; Sarli, V1
Brown, P; Chen, B; Cope, H; Heal, W; Mutter, R; Pascoe, C; Pratt, S1
Fukumura, T; Hatori, A; Irie, T; Kanno, I; Kawamura, K; Konno, F; Kumata, K; Suzuki, K; Yamasaki, T; Yui, J; Zhang, MR1
Sabisz, M; Skladanowski, A; Wesierska-Gadek, J1
Agarwal, S; Elmquist, WF; Gallardo, JL; Ohlfest, JR; Sane, R1
Balani, SK; Gan, L; Lee, FW; Liao, M; Liu, N; Milton, MN; Prakash, S; Wu, JT; Xia, CQ; Yang, JJ; Yu, S1
Al-Din, ES; El-Sabbagh, OI; Kadry, HH; Shabaan, MA1
Elmquist, WF; Mittapalli, RK; Sane, R1
Chen, C; Li, M; Pang, X; Su, X; Wen, L1
DeGroot, J; Jansen, HT; Kivits, S; Läppchen, T; Sio, CF; Steinbach, OC; van de Steeg, E; van der Hoorn, JW; van Driel, A; Vlaming, ML1
Bierbach, U; Ding, S1
Kanamitsu, K; Kusuhara, H; Schuetz, JD; Sugiyama, Y; Takeuchi, K1
Crish, JF; Elmquist, WF; Gampa, G; Hinojosa, AQ; Kenchappa, RS; Kim, M; Luu, A; Mohammad, AS; Parrish, KE; Rosenfeld, SS; Sarkaria, JN; West, R1

Reviews

15 review(s) available for quinazolines and acridines

ArticleYear
Quinoline, quinazoline, and acridone alkaloids.
    Natural product reports, 1992, Volume: 9, Issue:1

    Topics: Acridines; Alkaloids; Animals; Humans; Plants, Medicinal; Quinazolines; Quinolines

1992
Quinoline, quinazoline, and acridone alkaloids.
    Natural product reports, 1988, Volume: 5, Issue:3

    Topics: Acridines; Alkaloids; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

1988
Quinoline, quinazoline, and acridone alkaloids.
    Natural product reports, 1987, Volume: 4, Issue:3

    Topics: Acridines; Acridones; Alkaloids; Chemical Phenomena; Chemistry; Quinazolines; Quinolines

1987
Quinoline, quinazoline, and acridone alkaloids.
    Natural product reports, 1985, Volume: 2, Issue:5

    Topics: Acridines; Acridones; Alkaloids; Chemical Phenomena; Chemistry, Physical; Quinazolines; Quinolines

1985
Progress in malaria chemotherapy. 1. Repository antimalarial drugs.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1969, Volume: 13

    Topics: Acridines; Animals; Antimalarials; Chemical Phenomena; Chemistry; Dapsone; Delayed-Action Preparations; Guanidines; Injections; Methanol; Mice; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pyrimethamine; Quinazolines; Quinolines; Sulfonamides; Sulfones

1969
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 1997, Volume: 14, Issue:1

    Topics: Acridines; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Magnetic Resonance Spectroscopy; Molecular Structure; Plants; Quinazolines; Quinolines

1997
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 1999, Volume: 16, Issue:6

    Topics: Acridines; Alkaloids; Animals; Plants, Medicinal; Quinazolines; Quinolines

1999
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2000, Volume: 17, Issue:6

    Topics: Acridines; Acridones; Alkaloids; Animals; Molecular Structure; Quinazolines; Quinolines

2000
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2001, Volume: 18, Issue:5

    Topics: Acridines; Alkaloids; Amphibians; Animals; Antifungal Agents; Antimalarials; Antineoplastic Agents; Ants; Bacteria; Candida albicans; Coleoptera; Fungi; Molecular Structure; Plants, Medicinal; Plasmodium falciparum; Quinazolines; Quinolines; Rutaceae; Stereoisomerism; Structure-Activity Relationship

2001
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2002, Volume: 19, Issue:6

    Topics: Acridines; Acridones; Alkaloids; Animals; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

2002
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2003, Volume: 20, Issue:5

    Topics: Acridines; Acridones; Alkaloids; Animals; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

2003
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2004, Volume: 21, Issue:5

    Topics: Acridines; Acridones; Alkaloids; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

2004
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2005, Volume: 22, Issue:5

    Topics: Acridines; Acridones; Alkaloids; Animals; Bacteria; Fungi; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

2005
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2007, Volume: 24, Issue:1

    Topics: Acridines; Acridones; Alkaloids; Animals; Fungi; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

2007
Quinoline, quinazoline and acridone alkaloids.
    Natural product reports, 2008, Volume: 25, Issue:1

    Topics: Acridines; Acridones; Alkaloids; Animals; Fungi; Molecular Structure; Plants, Medicinal; Quinazolines; Quinolines

2008

Other Studies

15 other study(ies) available for quinazolines and acridines

ArticleYear
Anthranilic acid as precursor of alkaloids.
    Lloydia, 1969, Volume: 32, Issue:3

    Topics: Acridines; Alkaloids; Chemical Phenomena; Chemistry; ortho-Aminobenzoates; Pseudomonas aeruginosa; Quinazolines; Quinolines

1969
Inhibitors of platelet aggregation. 3. ((Dialkylamino)alkyl)thio heterocyclic compounds.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:1

    Topics: Acridines; Adenosine Diphosphate; Animals; Fibrinolytic Agents; Heterocyclic Compounds; Naphthyridines; Phenanthrolines; Platelet Adhesiveness; Quinazolines; Quinolines; Rabbits; Sulfhydryl Compounds; Xanthenes

1972
Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Flow Cytometry; Fluoresceins; Glioblastoma; Humans; Insecticides; Kinesins; Molecular Structure; Paclitaxel; Pyrimidines; Quinazolines; Rotenone; Spindle Apparatus; Tetrahydroisoquinolines; Thiones; Time Factors; Tubulin; Tubulin Modulators; Vinblastine

2007
Synthesis and SAR study of acridine, 2-methylquinoline and 2-phenylquinazoline analogues as anti-prion agents.
    European journal of medicinal chemistry, 2006, Volume: 41, Issue:10

    Topics: Acridines; Animals; Binding, Competitive; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Molecular Structure; Prions; Quinaldines; Quinazolines; Stereoisomerism; Structure-Activity Relationship

2006
In vivo evaluation of P-glycoprotein and breast cancer resistance protein modulation in the brain using [(11)C]gefitinib.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:3

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain; Carbon Radioisotopes; Gefitinib; Male; Mice; Neoplasm Proteins; Positron-Emission Tomography; Quinazolines; Radioactivity; Tetrahydroisoquinolines

2009
Increased cytotoxicity of an unusual DNA topoisomerase II inhibitor compound C-1305 toward HeLa cells with downregulated PARP-1 activity results from re-activation of the p53 pathway and modulation of mitotic checkpoints.
    Biochemical pharmacology, 2010, May-15, Volume: 79, Issue:10

    Topics: Acridines; Apoptosis; Blotting, Western; Cell Cycle; Cell Death; Cyclin B1; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Gene Expression Regulation; HeLa Cells; Humans; Mitosis; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polyploidy; Proteasome Endopeptidase Complex; Quinazolines; Topoisomerase II Inhibitors; Triazoles; Tumor Suppressor Protein p53

2010
Distribution of gefitinib to the brain is limited by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2)-mediated active efflux.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:1

    Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport, Active; Blood-Brain Barrier; Brain; Cell Line; Cell Membrane Permeability; Dogs; Gefitinib; Male; Mice; Mice, Knockout; Quinazolines; Tetrahydroisoquinolines; Tissue Distribution; Transfection

2010
P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
    Drug metabolism letters, 2010, Volume: 4, Issue:4

    Topics: Acridines; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Brain; Caco-2 Cells; Humans; Injections, Intravenous; Intestinal Mucosa; Male; Mice; Mice, Knockout; Neoplasm Proteins; Piperazines; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines

2010
Synthesis of new nonclassical acridines, quinolines, and quinazolines derived from dimedone for biological evaluation.
    Archiv der Pharmazie, 2010, Volume: 343, Issue:9

    Topics: Acridines; Anti-Bacterial Agents; Antineoplastic Agents; Cyclohexanones; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Microbial Sensitivity Tests; Quinazolines; Quinolines

2010
Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:4

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Brain; Cell Line; Dasatinib; Dogs; Drug Delivery Systems; Emulsions; Erlotinib Hydrochloride; Humans; Mice; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Solubility; Tetrahydroisoquinolines; Thiazoles

2013
Diverse tandem cyclization reactions of o-cyanoanilines and diaryliodonium salts with copper catalyst for the construction of quinazolinimine and acridine scaffolds.
    Organic letters, 2014, Dec-05, Volume: 16, Issue:23

    Topics: Acridines; Aniline Compounds; Catalysis; Copper; Cyclization; Heterocyclic Compounds, 4 or More Rings; Imines; Mesylates; Molecular Structure; Nitrogen; Onium Compounds; Quinazolines; Salts

2014
PET-CT imaging with [(18)F]-gefitinib to measure Abcb1a/1b (P-gp) and Abcg2 (Bcrp1) mediated drug-drug interactions at the murine blood-brain barrier.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:11

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Cell Line, Tumor; Drug Interactions; Fluorine Radioisotopes; Gefitinib; Humans; Male; Mice; Positron-Emission Tomography; Quinazolines; Tetrahydroisoquinolines; Tissue Distribution; Tomography, X-Ray Computed

2015
Linker design for the modular assembly of multifunctional and targeted platinum(ii)-containing anticancer agents.
    Dalton transactions (Cambridge, England : 2003), 2016, Aug-16, Volume: 45, Issue:33

    Topics: Acridines; Amines; Antineoplastic Agents; Dendrimers; Indoles; Organophosphorus Compounds; Platinum; Quinazolines; Tamoxifen

2016
Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4) in the Active Efflux of Anionic Drugs Across the Blood-Brain Barrier.
    Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:9

    Topics: 2,4-Dichlorophenoxyacetic Acid; Acridines; Adenosine Triphosphate; Animals; Biological Transport; Blood-Brain Barrier; Brain; Central Nervous System; Cyclic GMP; Humans; Kinetics; Male; Methotrexate; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Ochratoxins; Pravastatin; Quinazolines; Quinolines; Tetrahydroisoquinolines; Thiophenes; Uric Acid

2017
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
    Scientific reports, 2020, 04-16, Volume: 10, Issue:1

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzamides; Blood-Brain Barrier; Brain; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Glioblastoma; Humans; Kinesins; Mice; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasm Proteins; Quinazolines; Tetrahydroisoquinolines; Xenograft Model Antitumor Assays

2020