quinazolines has been researched along with 6,7-dimethoxy-2-(pyrrolidin-1-yl)-n-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Arrowsmith, CH; Bleich, RM; Brown, PJ; Butler, KV; Frye, SV; Herold, JM; Janzen, WP; Jin, J; Korboukh, V; Li, F; Ma, A; Norris, JL; Tripathy, A; Vedadi, M; Yu, W | 1 |
| Appella, E; Arrowsmith, CH; Giannini, G; Gryder, B; Hager, GL; Hu, Y; Jin, J; Khan, J; Lam, N; Liu, Z; Ma, A; Mazur, SJ; Ozbun, L; Souza, BK; Thiele, CJ; Veschi, V; Voss, TC; Yan, C | 1 |
| Fujii, T; Hamamoto, R; Honjoh, H; Inoue, F; Kaneko, S; Kashiyama, T; Kojima, M; Komatsu, M; Kukita, A; Miyamoto, Y; Mori-Uchino, M; Osuga, Y; Sone, K; Taguchi, A; Takahashi, Y; Tanikawa, M; Tsuruga, T; Wada, M; Wada-Hiraike, O | 1 |
3 other study(ies) available for quinazolines and 6,7-dimethoxy-2-(pyrrolidin-1-yl)-n-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine
| Article | Year |
|---|---|
Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
Topics: Calorimetry; Histone-Lysine N-Methyltransferase; Pyrrolidines; Quinazolines; Structure-Activity Relationship; Surface Plasmon Resonance | 2014 |
Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.
Topics: Cell Differentiation; Cell Proliferation; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Humans; Neuroblastoma; Quinazolines; RNA, Small Interfering; Tumor Suppressor Protein p53 | 2017 |
Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Inhibitory Concentration 50; Lysine; Ovarian Neoplasms; Prognosis; Quinazolines; RNA, Small Interfering; Transfection; Up-Regulation | 2020 |