Compounds > quinazolines
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quinazolines and 2-guanidine-4-methylquinazoline

quinazolines has been researched along with 2-guanidine-4-methylquinazoline in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (91.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Cao, H; Chen, Z; Feng, EG; Jiang, H; Li, WG; Liu, H; Xu, TL; Yu, F; Yu, Y1
Cao, H; Chen, Z; Jiang, H; Li, WG; Xu, TL; Yang, H; Yu, Y1
Alijevic, O; Kellenberger, S1
Xiao, X; Xu, TL; Zhu, MX1
Gonzales, EB; Smith, RN1
Acosta, MC; Callejo, G; Castany, M; Castellanos, A; Gallar, J; Gasull, X; Giblin, JP; Gual, A; Luna, C1
Gonzales, EB; Snell, HD1
Besson, T; Lingueglia, E; Salinas, M1
Cheng, XY; Hu, YM; Liang, H; Liu, Y; Lu, XY; Niu, YY; Tian, Y; Wang, HS; Wang, J; Xu, TL; Yang, XN; Yang, Y; Yu, Y; Zhu, MX1
Callejo, G; Schuhmacher, LN; Smith, ESJ; Srivats, S1
Lo, YC; So, EC; So, KH; Wang, Y; Wu, SN; Yang, LQ1
Andreopoulou, E; Callejo, G; Chakrabarti, S; Greenhalgh, JC; Hockley, JRF; Pattison, LA; Rahman, T; Smith, ESJ1

Other Studies

12 other study(ies) available for quinazolines and 2-guanidine-4-methylquinazoline

ArticleYear
A nonproton ligand sensor in the acid-sensing ion channel.
    Neuron, 2010, Oct-06, Volume: 68, Issue:1

    Topics: Acid Sensing Ion Channels; Acids; Amiloride; Animals; Behavior, Animal; Biophysics; Calcium; Cells, Cultured; Cricetinae; Cricetulus; Disease Models, Animal; Dithionitrobenzoic Acid; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Spinal; Glutamates; Guanidines; Hydrogen-Ion Concentration; Ion Channel Gating; Ligands; Membrane Potentials; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Pain; Pain Measurement; Patch-Clamp Techniques; Protein Structure, Tertiary; Protons; Quinazolines; Rats; Sensory Receptor Cells; Sodium Channels; Sulfhydryl Reagents; Time Factors; Transfection

2010
Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.
    The Journal of biological chemistry, 2011, Jul-15, Volume: 286, Issue:28

    Topics: Acid Sensing Ion Channels; Animals; Calcium; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Guanidines; Humans; Ion Channel Gating; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Quinazolines; Sodium Channels

2011
Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline.
    The Journal of biological chemistry, 2012, Oct-19, Volume: 287, Issue:43

    Topics: Acid Sensing Ion Channels; Animals; CHO Cells; Cricetinae; Cricetulus; Guanidines; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Protein Structure, Tertiary; Quinazolines; Rats; Xenopus laevis

2012
2-Guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type γ-aminobutyric acid receptors.
    Neuropharmacology, 2013, Volume: 75

    Topics: Acetylcholine; Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agents; GABA Agents; gamma-Aminobutyric Acid; Glycine; Guanidines; Hippocampus; Humans; In Vitro Techniques; Mutation; Neurons; Protein Subunits; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2013
Protons and Psalmotoxin-1 reveal nonproton ligand stimulatory sites in chicken acid-sensing ion channel: Implication for simultaneous modulation in ASICs.
    Channels (Austin, Tex.), 2014, Volume: 8, Issue:1

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Animals; Chickens; CHO Cells; Cricetulus; Guanidines; Ligands; Peptides; Protons; Quinazolines; Spider Venoms

2014
Acid-sensing ion channels detect moderate acidifications to induce ocular pain.
    Pain, 2015, Volume: 156, Issue:3

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acids; Action Potentials; Amiloride; Animals; Blinking; Cnidarian Venoms; Cornea; Disease Models, Animal; Dry Eye Syndromes; Eye; Guanidines; Guinea Pigs; Hydrogen-Ion Concentration; Male; Nerve Fibers; Ocular Motility Disorders; Ovalbumin; Pain; Patch-Clamp Techniques; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Sensory Receptor Cells; Statistics, Nonparametric

2015
Amiloride and GMQ Allosteric Modulation of the GABA-A ρ1 Receptor: Influences of the Intersubunit Site.
    The Journal of pharmacology and experimental therapeutics, 2015, Volume: 353, Issue:3

    Topics: Amiloride; Amino Acid Sequence; Cells, Cultured; Diuretics; Guanidines; Histamine H2 Antagonists; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Quinazolines; Receptors, GABA-A

2015
Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ).
    Neuropharmacology, 2017, Volume: 125

    Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Amiloride; Animals; Elapid Venoms; Guanidines; Hydrogen-Ion Concentration; Membrane Potentials; Oocytes; Peptides; Protein Domains; Quinazolines; Rats; Recombinant Fusion Proteins; Spider Venoms; Xenopus

2017
The nonproton ligand of acid-sensing ion channel 3 activates mollusk-specific FaNaC channels via a mechanism independent of the native FMRFamide peptide.
    The Journal of biological chemistry, 2017, 12-29, Volume: 292, Issue:52

    Topics: Acid Sensing Ion Channels; Animals; CHO Cells; Cricetulus; Crystallography, X-Ray; Degenerin Sodium Channels; Epithelial Sodium Channels; FMRFamide; Guanidines; Hydrogen-Ion Concentration; Ion Channel Gating; Ligands; Mollusca; Oocytes; Peptides; Quinazolines; Xenopus laevis

2017
Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers.
    The Journal of biological chemistry, 2018, 02-02, Volume: 293, Issue:5

    Topics: Acid Sensing Ion Channels; Animals; Cell Membrane; Guanidines; Mole Rats; Protein Multimerization; Protein Subunits; Quinazolines

2018
Multiple regulatory actions of 2-guanidine-4-methylquinazoline (GMQ), an agonist of acid-sensing ion channel type 3, on ionic currents in pituitary GH
    Biochemical pharmacology, 2018, Volume: 151

    Topics: Acid Sensing Ion Channels; Action Potentials; Animals; Cell Line, Tumor; Guanidines; Ion Channel Gating; Ion Transport; Olfactory Receptor Neurons; Patch-Clamp Techniques; Pituitary Gland; Quinazolines; Rats; Sodium Channel Agonists

2018
In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3.
    Biochemical pharmacology, 2020, Volume: 174

    Topics: Acid Sensing Ion Channels; Allosteric Regulation; Animals; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Guanabenz; Guanidines; Protein Structure, Secondary; Quinazolines

2020