quinaprilat has been researched along with losartan in 7 studies
| Studies (quinaprilat) | Trials (quinaprilat) | Recent Studies (post-2010) (quinaprilat) | Studies (losartan) | Trials (losartan) | Recent Studies (post-2010) (losartan) |
|---|---|---|---|---|---|
| 92 | 23 | 4 | 7,231 | 1,245 | 2,118 |
| Protein | Taxonomy | quinaprilat (IC50) | losartan (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 9.01 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.882 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.019 | |
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.0018 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0247 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0234 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0032 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.047 | |
| Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.025 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0118 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.019 | |
| Platelet glycoprotein VI | Homo sapiens (human) | 4 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.1481 | |
| Type-1 angiotensin II receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.2884 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Allegrini, PR; Buser, PT; Hornstein, PS; Zaugg, CE; Zhu, P | 1 |
| Appenroth, D; Beutinger, R; Fleck, C; Lupp, A | 1 |
| Cosentino, F; Delli Gatti, C; Eto, M; Kouroedov, A; Lüscher, TF; Osto, E; Shaw, S; Volpe, M | 1 |
| Balachandran, K; Ozkizilcik, A; Patel, S; Sysavanh, F; Tandon, I | 1 |
7 other study(ies) available for quinaprilat and losartan
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Bradykinin-dependent cardioprotective effects of losartan against ischemia and reperfusion in rat hearts.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Circulation; In Vitro Techniques; Isoquinolines; Losartan; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrahydroisoquinolines; Ventricular Function, Left; Ventricular Pressure | 1999 |
Effects of a therapy with losartan and quinaprilat on the progression of chronic renal failure in rats after a single dose of uranyl nitrate or 5/6 nephrectomy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Female; Hydroxyproline; Injections, Intraperitoneal; Kidney Failure, Chronic; Losartan; Nephrectomy; p-Aminohippuric Acid; Proteinuria; Rats; Rats, Wistar; Tetrahydroisoquinolines; Uranyl Nitrate | 2003 |
Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomechanical Phenomena; Cells, Cultured; Endothelial Cells; Hemorheology; Humans; Losartan; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Pulsatile Flow; Renin-Angiotensin System; Stress, Mechanical; Superoxides; Tetrahydroisoquinolines | 2008 |
Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve; Cells, Cultured; Fluorescent Antibody Technique; Losartan; Myofibroblasts; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Swine; Tetrahydroisoquinolines | 2021 |