quinaprilat has been researched along with captopril in 15 studies
| Studies (quinaprilat) | Trials (quinaprilat) | Recent Studies (post-2010) (quinaprilat) | Studies (captopril) | Trials (captopril) | Recent Studies (post-2010) (captopril) |
|---|---|---|---|---|---|
| 92 | 23 | 4 | 10,320 | 1,514 | 890 |
| Protein | Taxonomy | quinaprilat (IC50) | captopril (IC50) |
|---|---|---|---|
| Leukotriene A-4 hydrolase | Homo sapiens (human) | 3.6 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.084 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.0173 | |
| Succinyl-diaminopimelate desuccinylase | Haemophilus influenzae Rd KW20 | 3.3 | |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | 0.1004 | |
| Beta-lactamase | Pseudomonas aeruginosa | 5 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 0.011 | |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | 3.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, D; Essenburg, AD; Kaplan, HR; Roark, WH; Tinney, FJ | 1 |
| Blankley, CJ; Cohen, DM; Essenburg, AD; Fleming, RW; Hinkley, JM; Hoefle, ML; Holmes, A; Klutchko, S; Nordin, I; Werner, AE | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Dargie, HJ; Dominiczak, M; Godfrey, EG; Hamilton, CA; McMurray, J; Reid, JL; Stewart, J | 1 |
| Benigno, M; Bernocchi, P; Boraso, A; Cargnoni, A; Ferrari, R; Ghirardelli, N; Pedersini, P; Scotti, C | 1 |
| Bumpus, FM; Husain, A; Kinoshita, A; Urata, H | 1 |
| Anning, PB; Grocott-Mason, RM; Lewis, MJ | 1 |
| Akarawut, W; Lin, CJ; Smith, DE | 1 |
| Fabre, JE; Isner, JM; Magner, M; Rivard, A; Silver, M | 1 |
| Danser, AH; de Vries, R; Saxena, PR; Tom, B | 1 |
| Batenburg, WW; Danser, AH; de Bruijn, RJ; de Vries, R; Dive, V; Georgiadis, D; Tom, B; van Esch, JH; van Gool, JM; Yiotakis, A | 1 |
| Briggs, JP; Chen, L; Faulhaber-Walter, R; Huang, Y; Kim, SM; Mizel, D; Oppermann, M; Schnermann, J | 1 |
| Briggs, JP; Chen, L; Chen, M; Eisner, C; Gomez, RA; Huang, Y; Kim, SM; Li, L; Mizel, D; Oppermann, M; Schnermann, J; Sequeira Lopez, ML; Weinstein, LS | 1 |
15 other study(ies) available for quinaprilat and captopril
| Article | Year |
|---|---|
Synthesis and biological activity of modified peptide inhibitors of angiotensin-converting enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Chemical Phenomena; Chemistry; Dipeptides; Enalapril; Guinea Pigs; Hypertension, Renal; Indoles; Isoquinolines; Quinapril; Rats; Structure-Activity Relationship; Tetrahydroisoquinolines | 1985 |
Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Isoquinolines; Male; Molecular Conformation; Quinapril; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrahydroisoquinolines | 1986 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Effects of ACE inhibitors on oxidation of human low density lipoprotein.
Topics: Acetylcysteine; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Captopril; Copper; Female; Humans; Isoquinolines; Lipoproteins, LDL; Oxidation-Reduction; Tetrahydroisoquinolines | 1994 |
Effect of angiotensin converting enzyme inhibition with quinaprilat on the ischaemic and reperfused myocardium.
Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Creatine Kinase; Heart; Homeostasis; Isoquinolines; Lactates; Lactic Acid; Male; Myocardial Reperfusion Injury; Norepinephrine; Oxidation-Reduction; Phosphocreatine; Rabbits; Tetrahydroisoquinolines | 1994 |
Measurement of angiotensin I converting enzyme inhibition in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Captopril; Cricetinae; Dipeptides; Enalaprilat; Humans; Isoquinolines; Lisinopril; Male; Mesocricetus; Papillary Muscles; Tetrahydroisoquinolines | 1993 |
Effects of sulphydryl- and non-sulphydryl-containing ACE inhibitors on left ventricular relaxation in the isolated guinea pig heart.
Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diastole; Female; Free Radical Scavengers; Guinea Pigs; Heart Ventricles; Hemoglobins; Isoquinolines; Lisinopril; Male; Muscle Relaxation; Nitric Oxide; Receptor, Bradykinin B2; Simethicone; Stroke Volume; Sulfhydryl Compounds; Superoxide Dismutase; Systole; Tetrahydroisoquinolines; Ventricular Dysfunction, Left | 1997 |
Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Captopril; Carrier Proteins; Cell Membrane; Dipeptides; Dose-Response Relationship, Drug; Enalapril; Fosinopril; Isoquinolines; Kidney; Kinetics; Lipid Metabolism; Lipids; Lisinopril; Male; Microvilli; Peptide Transporter 1; Quinapril; Rabbits; Ramipril; Symporters; Tetrahydroisoquinolines | 1999 |
Tissue inhibition of angiotensin-converting enzyme activity stimulates angiogenesis in vivo.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Artery, Common; Endothelial Growth Factors; Femoral Artery; Hemodynamics; Hindlimb; Humans; Isoquinolines; Lymphokines; Muscle, Smooth, Vascular; Neovascularization, Physiologic; Peptidyl-Dipeptidase A; Rabbits; Recombinant Proteins; Regional Blood Flow; Tetrahydroisoquinolines; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vascular Resistance; Vasodilation | 1999 |
Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Drug Synergism; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Receptor, Bradykinin B2; Receptors, Bradykinin; Swine; Tetrahydroisoquinolines; Vasodilation | 2001 |
Selective angiotensin-converting enzyme C-domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Male; Microcirculation; Middle Aged; Oligopeptides; Organ Specificity; Peptidyl-Dipeptidase A; Phosphinic Acids; Protein Structure, Tertiary; Solubility; Structure-Activity Relationship; Sus scrofa; Tetrahydroisoquinolines; Vasoconstriction | 2005 |
Regulation of renin secretion and expression in mice deficient in beta1- and beta2-adrenergic receptors.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Furosemide; Mice; Mice, Knockout; Osmolar Concentration; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Renin; RNA, Messenger; Sodium Chloride, Dietary; Tetrahydroisoquinolines; Tetrazoles | 2007 |
Stimulation of renin secretion by angiotensin II blockade is Gsalpha-dependent.
Topics: Adenylyl Cyclases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Catecholamines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enalapril; Female; GTP-Binding Protein alpha Subunits, Gs; Juxtaglomerular Apparatus; Male; Mice; Mice, Knockout; Models, Animal; Nitric Oxide; Prostaglandins; Renin; Signal Transduction; Tetrahydroisoquinolines; Tetrazoles | 2010 |