quinaprilat has been researched along with bradykinin in 13 studies
| Studies (quinaprilat) | Trials (quinaprilat) | Recent Studies (post-2010) (quinaprilat) | Studies (bradykinin) | Trials (bradykinin) | Recent Studies (post-2010) (bradykinin) |
|---|---|---|---|---|---|
| 92 | 23 | 4 | 14,195 | 355 | 1,520 |
| Protein | Taxonomy | quinaprilat (IC50) | bradykinin (IC50) |
|---|---|---|---|
| B2 bradykinin receptor | Homo sapiens (human) | 0.0018 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (69.23) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bara, AT; Busse, R; Hecker, M; Pörsti, I | 1 |
| Jackson, B; Johnston, CI; Perich, RB | 1 |
| Drexler, H; Hornig, B; Kohler, C | 1 |
| Haefeli, WE; Linder, L; Lüscher, TF | 1 |
| Anning, PB; Grocott-Mason, RM; Lewis, MJ | 1 |
| Arakawa, N; Drexler, H; Hornig, B | 1 |
| Abiko, Y; Hara, A; Hashizume, H; Ma, H; Yazawa, K | 1 |
| Allegrini, PR; Buser, PT; Hornstein, PS; Zaugg, CE; Zhu, P | 1 |
| Adnot, S; Belhassen, L; Benacerraf, S; Carville, C; Dubois-Randé, JL; Montagne, O; Sediame, S | 1 |
| Fujita, N; Manabe, H; Masui, Y; Matsumoto, N; Naito, Y; Ochiai, J; Uemura, M; Yoshida, N; Yoshikawa, T | 1 |
| Danser, AH; de Vries, R; Saxena, PR; Tom, B | 1 |
| Batenburg, WW; Danser, AH; de Bruijn, RJ; de Vries, R; Dive, V; Georgiadis, D; Tom, B; van Esch, JH; van Gool, JM; Yiotakis, A | 1 |
| de Bruin, RJ; Deinum, J; Dive, V; Hectors, M; Jan Danser, AH; Montgomery, HE; Payne, JR; van Esch, JH; van Gool, JM | 1 |
1 review(s) available for quinaprilat and bradykinin
| Article | Year |
|---|---|
Effect of ACE inhibition on endothelial dysfunction in patients with chronic heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Disease; Endothelium, Vascular; Heart Failure; Humans; Isoquinolines; Nitric Oxide; Tetrahydroisoquinolines; Treatment Outcome; Vasodilation | 1998 |
1 trial(s) available for quinaprilat and bradykinin
| Article | Year |
|---|---|
Improvement of bradykinin endothelium-mediated vasodilation of forearm resistance circulation by quinaprilat in patients with coronary artery disease with or without left ventricular dysfunction.
Topics: Acetylcholine; Adult; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Bradykinin; Coronary Angiography; Coronary Disease; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Forearm; Humans; Isoquinolines; Male; Middle Aged; Platelet Aggregation Inhibitors; Regional Blood Flow; Renin; Tetrahydroisoquinolines; Vasodilation; Vasomotor System; Ventricular Dysfunction, Left | 1999 |
11 other study(ies) available for quinaprilat and bradykinin
| Article | Year |
|---|---|
Release of nitric oxide by angiotensin-(1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Arginine; Bradykinin; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Isoquinolines; Molecular Sequence Data; Muscle Relaxation; Nitric Oxide; Nitroarginine; Peptide Fragments; Receptors, Angiotensin; Swine; Tetrahydroisoquinolines; Vasodilator Agents | 1994 |
Structural constraints of inhibitors for binding at two active sites on somatic angiotensin converting enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Bradykinin; Dipeptides; Indoles; Isoquinolines; Kidney; Lisinopril; Lung; Male; Peptidyl-Dipeptidase A; Pyridazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Substrate Specificity; Testis; Tetrahydroisoquinolines | 1994 |
Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans.
Topics: Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Bradykinin Receptor Antagonists; Drug Interactions; Endothelium, Vascular; Female; Humans; Hyperemia; Isoquinolines; Male; Nitroprusside; Radial Artery; Regional Blood Flow; Tetrahydroisoquinolines; Ultrasonography, Doppler; Vasodilation | 1997 |
Quinaprilat induces arterial vasodilation mediated by nitric oxide in humans.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arteries; Bradykinin; Female; Humans; Isoquinolines; Male; Nitric Oxide; Nitroprusside; Regional Blood Flow; Tetrahydroisoquinolines; Vasodilation; Vasodilator Agents | 1997 |
Effects of sulphydryl- and non-sulphydryl-containing ACE inhibitors on left ventricular relaxation in the isolated guinea pig heart.
Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diastole; Female; Free Radical Scavengers; Guinea Pigs; Heart Ventricles; Hemoglobins; Isoquinolines; Lisinopril; Male; Muscle Relaxation; Nitric Oxide; Receptor, Bradykinin B2; Simethicone; Stroke Volume; Sulfhydryl Compounds; Superoxide Dismutase; Systole; Tetrahydroisoquinolines; Ventricular Dysfunction, Left | 1997 |
Protective effect of quinaprilat, an active metabolite of quinapril, on Ca2+-overload induced by lysophosphatidylcholine in isolated rat cardiomyocytes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Calcium; Cell Size; Creatine Kinase; Enalapril; Enalaprilat; Isoquinolines; Lysophosphatidylcholines; Male; Micelles; Myocardium; Propranolol; Quinapril; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Vasodilator Agents | 1999 |
Bradykinin-dependent cardioprotective effects of losartan against ischemia and reperfusion in rat hearts.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Circulation; In Vitro Techniques; Isoquinolines; Losartan; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrahydroisoquinolines; Ventricular Function, Left; Ventricular Pressure | 1999 |
Inhibition of angiotensin-converting enzyme protects endothelial cell against hypoxia/reoxygenation injury.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aorta; Apoptosis; Bradykinin; Caspase 3; Caspases; Cell Hypoxia; Cell Line; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Isoquinolines; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen; Reactive Oxygen Species; Reperfusion Injury; Tetrahydroisoquinolines | 2000 |
Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Drug Synergism; Female; Humans; In Vitro Techniques; Isoquinolines; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Receptor, Bradykinin B2; Receptors, Bradykinin; Swine; Tetrahydroisoquinolines; Vasodilation | 2001 |
Selective angiotensin-converting enzyme C-domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Coronary Vessels; Dose-Response Relationship, Drug; Female; Femoral Artery; Humans; Male; Microcirculation; Middle Aged; Oligopeptides; Organ Specificity; Peptidyl-Dipeptidase A; Phosphinic Acids; Protein Structure, Tertiary; Solubility; Structure-Activity Relationship; Sus scrofa; Tetrahydroisoquinolines; Vasoconstriction | 2005 |
Different contributions of the angiotensin-converting enzyme C-domain and N-domain in subjects with the angiotensin-converting enzyme II and DD genotype.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Vessels; Enzyme Activation; Female; Genotype; Humans; In Vitro Techniques; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Phosphinic Acids; Point Mutation; Protein Structure, Tertiary; Sus scrofa; Tetrahydroisoquinolines; Vasoconstrictor Agents; Vasodilator Agents | 2008 |