Compounds > quinacrine

quinacrine and vorinostat

quinacrine has been researched along with vorinostat in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Belkhiri, A; Chen, Z; El-Rifai, W; Lockhart, AC; Peng, D; Wang, L; Zhu, S1
Deng, J; Jin, J; Jing, B; Lei, H; Liu, M; Liu, W; Tong, Y; Wu, Y; Xiang, R; Xiao, X; Xu, H; Yang, L; Zhou, L1

Other Studies

4 other study(ies) available for quinacrine and vorinostat

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A Combination of SAHA and Quinacrine Is Effective in Inducing Cancer Cell Death in Upper Gastrointestinal Cancers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 04-15, Volume: 24, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Disease Models, Animal; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Gastrointestinal Neoplasms; Genes, Reporter; Histone Deacetylase Inhibitors; Humans; Mice; Mutation; Quinacrine; Tumor Suppressor Protein p53; Vorinostat; Xenograft Model Antitumor Assays

2018
Vorinostat and quinacrine have synergistic effects in T-cell acute lymphoblastic leukemia through reactive oxygen species increase and mitophagy inhibition.
    Cell death & disease, 2018, 05-22, Volume: 9, Issue:6

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Membrane Potential, Mitochondrial; Mice, Inbred NOD; Mice, SCID; Mitochondria; Mitophagy; Models, Biological; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Quinacrine; Reactive Oxygen Species; Vorinostat

2018