quinacrine and verapamil

quinacrine has been researched along with verapamil in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199016 (29.63)18.7374
1990's21 (38.89)18.2507
2000's10 (18.52)29.6817
2010's7 (12.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daiku, Y; Hamano, S; Hasegawa, T; Kakisawa, H; Minami, N; Naitoh, T; Nomoto, K; Oinuma, H; Takamura, T1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chen, X; Chong, CR; Liu, JO; Shi, L; Sullivan, DJ1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Doh-Ura, K; Go, ML; Nguyen, T; Sakasegawa, Y1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Nicholson, GC; Papadimitriou, JM; Wood, DJ; Zheng, MH1
Baba, A; Matsuda, T; Shimizu, I1
Belzer, FO; Claesson, K; Lindell, S; Southard, JH1
Boesch, D; Loor, F; Muller, K; Pourtier-Manzanedo, A1
Kavaler, F; Shepherd, N; Spielman, W1
Heller, PH; Levine, JD; Taiwo, YO1
Fletcher, JE; Huggins, FJ; Rosenberg, H1
Gandhi, VC; Jones, DJ1
Das, DK; Jones, RM; Otani, H; Prasad, MR1
Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG1
Boscoboinik, D; Epand, RM1
Azuma, H; Nakajima, T; Satoh, A; Sekizaki, S1
Beck, WT; Cirtain, MC; Felsted, RL; Glover, CJ; Safa, AR1
Barnes, PJ; Cuss, FM; Grandordy, BM1
Danon, A; Davis, BB; Thomasson, DL; Zenser, TV1
Dorman, RV; Schwartz, MA; Terrian, DM1
Piper, PJ; Stewart, AG1
Beck, WT; Pearce, HL; Zamora, JM1
Bowers, CY; Chang, D; Sartor, O1
Kimura, T; Satoh, S1
Clark, JS; Jubb, SN; Maloney, PJ; Young, JM1
Battisti, L; DeLellis, R; Donowitz, M; Pike, G; Wicks, J1
Imanishi, S; Miyamae, S1
Gustafsson, JA; Hamberg, M; Mode, A; Tollet, P1
Käfer, A; Krug, HF1
Li, ZY; Lian, EC; Yu, TF1
Andersson, R; Ar'Rajab, A; Bengmark, S; Fabia, R; Willén, R1
Marcil, J; Ravindranath, N; Sairam, MR1
Arnould, T; Dieu, M; Knott, I; Michiels, C; Remacle, J1
Haque, A; Horiguchi, Y; Matsuda, M; Sugimoto, N1
Chang, JP; Garofalo, R; Neumann, CM1
Dazy, AC; Diogène, G; Marano, F; Venant, A1
López-Novoa, JM; Martínez-Salgado, C; Pérez de Lema, G; Rodríguez-Barbero, A; Rodríguez-Puyol, D1
Miller, DS; Pritchard, JB; Villalobos, AR1
Isoda, T; Kass, DA; Pagliaro, P; Paolocci, N; Recchia, FA; Senzaki, H; Sunagawa, G1
Bodin, P; Burnstock, G1
Castaing, M; Djoudi, L; Loiseau, A1
Dohgu, S; Higuchi, S; Katamine, S; Kataoka, Y; Naito, M; Niwa, M; Sawada, Y; Shirabe, S; Takata, F; Tsuruo, T; Yamauchi, A1
Eguchi, K; Katamine, S; Kataoka, Y; Nishida, N; Niwa, M; Satoh, K; Shirabe, S; Yamauchi, A1
Leader, JP; O'Donnell, MJ1
Balogh, Z; Fóris, G; Fülöp, P; Kassai, A; Kosztáczky, B; Paragh, G; Seres, I; Varga, Z1
Choi, YS; Hah, YS; Hwang, EM; Jeong, YS; Lee, SH; Ok, SH; Park, JY; Shin, IW; Sohn, JT1
Lehane, AM; Martin, RE; Nash, MN; Shafik, SH; Smith, PJ; Summers, RL; van Schalkwyk, DA1

Other Studies

54 other study(ies) available for quinacrine and verapamil

ArticleYear
Synthesis and biological evaluation of substituted benzenesulfonamides as novel potent membrane-bound phospholipase A2 inhibitors.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Animals; Benzene Derivatives; Cell Membrane; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Heart; Male; Myocardial Infarction; Phospholipases A; Phospholipases A2; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfonamides

1991
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A clinical drug library screen identifies astemizole as an antimalarial agent.
    Nature chemical biology, 2006, Volume: 2, Issue:8

    Topics: Animals; Antimalarials; Astemizole; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple; Humans; Mice; Plasmodium falciparum; Plasmodium yoelii

2006
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Anti-prion activities and drug-like potential of functionalized quinacrine analogs with basic phenyl residues at the 9-amino position.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Blood-Brain Barrier; Cell Line, Tumor; Dogs; Humans; Madin Darby Canine Kidney Cells; Mice; Peptide Fragments; Permeability; Piperazines; Piperidines; Prion Diseases; Prions; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Evidence that protein kinase-A, calcium-calmodulin kinase and cytoskeletal proteins are involved in osteoclast retraction induced by calcitonin.
    Experimental and molecular pathology, 1992, Volume: 57, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Resorption; Calcitonin; Cells, Cultured; Colchicine; Colforsin; Cytoskeletal Proteins; In Vitro Techniques; Isoquinolines; Neomycin; Osteoclasts; Phospholipases A; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Quinacrine; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Verapamil

1992
Na+ influx-induced decrease of (Na+ + K+)-ATPase activity in rat brain slices: role of Ca2+.
    European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3

    Topics: Amiloride; Animals; Bepridil; Brain; Calcium; Calcium Channel Blockers; Cell Membrane; Chelating Agents; Diazepam; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Monensin; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Quinacrine; Rats; Rats, Inbred Strains; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil; Veratrine

1991
Chlorpromazine, quinacrine, and verapamil as donor pretreatment in liver preservation, tested in the isolated perfused rat liver.
    Cryobiology, 1991, Volume: 28, Issue:5

    Topics: Animals; Bile; Chlorpromazine; Cold Temperature; Cryoprotective Agents; Drug Evaluation, Preclinical; Enzymes; In Vitro Techniques; Liver; Male; Organ Preservation; Perfusion; Quinacrine; Rats; Rats, Inbred Strains; Tissue Donors; Verapamil

1991
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative.
    Experimental cell research, 1991, Volume: 196, Issue:1

    Topics: Amiodarone; Animals; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Flow Cytometry; Leukemia, Experimental; Leukemia, Myeloid; Microscopy, Fluorescence; Quinacrine; Quinidine; Tumor Cells, Cultured; Verapamil

1991
Cadmium block of isometric contractions of isolated bullfrog atrial cells.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Animals; Atrial Function; Cadmium; Electric Stimulation; Heart Atria; In Vitro Techniques; Kinetics; Myocardial Contraction; Quinacrine; Rana catesbeiana; Sodium; Verapamil

1991
Characterization of distinct phospholipases mediating bradykinin and noradrenaline hyperalgesia.
    Neuroscience, 1990, Volume: 39, Issue:2

    Topics: Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Fluorescent Dyes; Hyperalgesia; Male; Neomycin; Nociceptors; Norepinephrine; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Inbred Strains; Skin; Type C Phospholipases; Verapamil

1990
The importance of calcium ions for in vitro malignant hyperthermia testing.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Quinacrine; Strontium; Succinylcholine; Verapamil

1990
Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Kinetics; Male; Nifedipine; Nitrendipine; Quinacrine; Rats; Rats, Inbred Strains; Spinal Cord; Trifluoperazine; Verapamil

1988
Mechanism of membrane phospholipid degradation in ischemic-reperfused rat hearts.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Coronary Disease; Fatty Acids, Nonesterified; Glycerol; Male; Membrane Lipids; Myocardial Reperfusion; Myocardium; Phospholipids; Quinacrine; Rats; Rats, Inbred Strains; Trifluoperazine; Verapamil

1989
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria.
    Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2

    Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil

1989
Increased cellular internalization of amphiphiles in a multidrug-resistant CHO cell line.
    Biochimica et biophysica acta, 1989, Oct-30, Volume: 1014, Issue:1

    Topics: Animals; Biological Transport; Carnitine; Cell Line; Cell Membrane; Cricetinae; Cyclosporins; Diffusion; Drug Resistance; Kinetics; Lysophosphatidylcholines; Palmitoylcarnitine; Quinacrine; Solubility; Verapamil

1989
Platelet aggregation caused by Carybdea rastonii toxins (CrTX-I, II and III) obtained from a jellyfish, Carybdea rastonii.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 182, Issue:1

    Topics: Animals; Blood Platelets; Calcium; Cell Membrane; Chromatography, Gel; Cnidarian Venoms; Dose-Response Relationship, Drug; Indomethacin; Membrane Potentials; Platelet Aggregation; Quinacrine; Rabbits; Scyphozoa; Sodium; Verapamil

1986
Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine.
    Biochemical and biophysical research communications, 1988, Jun-30, Volume: 153, Issue:3

    Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Survival; Chloroquine; Drug Interactions; Drug Resistance; Humans; Indoles; Leukemia; Membrane Glycoproteins; Photochemistry; Quinacrine; Quinine; Reserpine; Verapamil; Vinblastine; Vinca Alkaloids; Vindesine; Yohimbine

1988
Breakdown of phosphoinositides in airway smooth muscle: lack of influence of anti-asthmatic drugs.
    Life sciences, 1987, Sep-28, Volume: 41, Issue:13

    Topics: Animals; Carbachol; Cattle; Dexamethasone; Histamine; Hydrolysis; Isoproterenol; Muscle Contraction; Phosphatidylinositols; Phospholipases; Quinacrine; Theophylline; Trachea; Verapamil

1987
Effect of verapamil on prostaglandin E2 synthesis by hydronephrotic rabbit cortical interstitial cells in primary culture.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Diltiazem; Dinoprostone; Dose-Response Relationship, Drug; Hydronephrosis; Kidney Cortex; Magnesium; Male; Nifedipine; Prostaglandins E; Quinacrine; Rabbits; Trifluoperazine; Verapamil

1986
Depolarization-induced [3H]arachidonic acid accumulation: effects of external Ca2+ and phospholipase inhibitors.
    Brain research bulletin, 1988, Volume: 21, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium Channel Blockers; Cerebellum; Dibucaine; Enzyme Inhibitors; Phospholipases; Quinacrine; Rats; Verapamil

1988
Vasodilator actions of acetylcholine, A23187 and bradykinin in the guinea-pig isolated perfused heart are independent of prostacyclin.
    British journal of pharmacology, 1988, Volume: 95, Issue:2

    Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Calcimycin; Coronary Circulation; Diethylcarbamazine; Epoprostenol; Guinea Pigs; In Vitro Techniques; Male; Quinacrine; Vasodilation; Verapamil

1988
Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.
    Molecular pharmacology, 1988, Volume: 33, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry, Physical; Chloroquine; Computer Simulation; Doxorubicin; Drug Resistance; Humans; Leukemia; Naphthacenes; Podophyllotoxin; Quinacrine; Verapamil; Vinca Alkaloids

1988
Parallel studies of His-DTrp-Ala-Trp-DPhe-Lys-NH2 and human pancreatic growth hormone-releasing factor-44-NH2 in rat primary pituitary cell monolayer culture.
    Endocrinology, 1985, Volume: 116, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cadmium; Cadmium Chloride; Dose-Response Relationship, Drug; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Oligopeptides; Peptide Fragments; Pituitary Gland; Quinacrine; Rats; Rats, Inbred Strains; Verapamil

1985
Inhibitory effect of quinacrine on myocardial reactive hyperemia in the dog.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Acetylcholine; Adenosine; Animals; Blood Flow Velocity; Catechols; Coronary Circulation; Dogs; Female; Heart Rate; Hyperemia; Indomethacin; Male; Masoprocol; Pyrazoles; Quinacrine; Regional Blood Flow; Theophylline; Verapamil

1985
Pharmacological investigation of the mechanisms of platelet-activating factor induced mortality in the mouse.
    Prostaglandins, 1985, Volume: 30, Issue:4

    Topics: Anaphylaxis; Animals; Chloroquine; Chlortetracycline; Dexamethasone; Dose-Response Relationship, Drug; Female; Indomethacin; Injections, Intravenous; Male; Mice; Mice, Inbred DBA; Naproxen; Nicardipine; Nifedipine; Platelet Activating Factor; Pyrazoles; Quinacrine; Tetracycline; Verapamil

1985
Effect of Senokot on rat intestinal electrolyte transport. Evidence of Ca++ dependence.
    Gastroenterology, 1984, Volume: 87, Issue:3

    Topics: Adenylyl Cyclases; Animals; Biological Transport, Active; Calcium; Chlorides; Colon; Cyclic AMP; Intestinal Mucosa; Jejunum; Male; Quinacrine; Rats; Rats, Inbred Strains; Senna Extract; Sodium; Verapamil

1984
Hyperpolarization induced by sodium removal in rabbit sinoatrial node cells. Possible role of electrogenic sodium-calcium exchange.
    Journal of electrocardiology, 1995, Volume: 28, Issue:2

    Topics: Animals; Calcium; In Vitro Techniques; Lidocaine; Membrane Potentials; Ouabain; Quinacrine; Quinidine; Rabbits; Sinoatrial Node; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil

1995
Growth hormone signaling leading to CYP2C12 gene expression in rat hepatocytes involves phospholipase A2.
    The Journal of biological chemistry, 1995, May-26, Volume: 270, Issue:21

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Diglycerides; Enzyme Activation; Gene Expression Regulation; Growth Hormone; Insulin-Like Growth Factor I; Ketoconazole; Lactams, Macrocyclic; Liver; Phospholipases A; Phospholipases A2; Phospholipids; Phosphorylation; Proadifen; Protein-Tyrosine Kinases; Quinacrine; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Verapamil

1995
Effects of organometals on cellular signaling. I. Influence of metabolic inhibitors on metal-induced arachidonic acid liberation.
    Environmental health perspectives, 1994, Volume: 102 Suppl 3

    Topics: Arachidonic Acid; Calcium; Cell Communication; Culture Media; Egtazic Acid; Homeostasis; Humans; Organometallic Compounds; Pertussis Toxin; Phospholipases A; Phospholipases A2; Quinacrine; Tumor Cells, Cultured; Verapamil; Virulence Factors, Bordetella

1994
Purification and characterization of L-amino acid oxidase from king cobra (Ophiophagus hannah) venom and its effects on human platelet aggregation.
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:11

    Topics: Alprostadil; Amino Acid Oxidoreductases; Animals; Antimycin A; Aspirin; Blood Coagulation Tests; Blood Platelets; Catalase; Chromatography, Gel; Chromatography, Ion Exchange; Drug Interactions; Edetic Acid; Elapid Venoms; Electrophoresis, Polyacrylamide Gel; Heparin; Hirudins; Humans; Hydrogen Peroxide; Indomethacin; Isoelectric Point; L-Amino Acid Oxidase; Molecular Weight; Nitroprusside; Platelet Aggregation; Quinacrine; Thromboxane A2; Verapamil

1994
Effect of putative phospholipase A2 inhibitors on acetic acid-induced acute colitis in the rat.
    The British journal of surgery, 1993, Volume: 80, Issue:9

    Topics: Acetates; Acetic Acid; Acetophenones; Animals; Colitis; Colon; Enzyme Activation; Female; Intestinal Mucosa; Peroxidase; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Sprague-Dawley; Verapamil

1993
Cytotoxic activity of lutropin-gelonin conjugate in mouse Leydig tumor cells: potentiation of the hormonotoxin activity by different drugs.
    Molecular and cellular endocrinology, 1993, Volume: 92, Issue:1

    Topics: Animals; Antineoplastic Agents; Chloroquine; Drug Screening Assays, Antitumor; Drug Synergism; Leydig Cell Tumor; Leydig Cells; Luteinizing Hormone; Male; Mice; Monensin; Neoplasm Proteins; Plant Proteins; Progesterone; Protein Synthesis Inhibitors; Quinacrine; Receptors, LH; Ribosome Inactivating Proteins, Type 1; Testicular Neoplasms; Tumor Cells, Cultured; Verapamil

1993
Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acid; Calcium; Carbon Radioisotopes; Cell Hypoxia; Endothelium, Vascular; Humans; Indomethacin; Kinetics; Oxygen; Phospholipases A; Phospholipases A2; Prostaglandins; Quinacrine; Stearic Acids; Tritium; Umbilical Veins; Verapamil

1993
Coronary vasoconstriction is the most probable cause of death of rats intoxicated with botulinolysin, a hemolysin produced by Clostridium botulinum.
    Toxicon : official journal of the International Society on Toxinology, 1995, Volume: 33, Issue:9

    Topics: Animals; Aspirin; Blood Pressure; Botulinum Toxins; Botulism; Clostridium botulinum; Electrocardiography; Female; Heart Atria; Hemolysis; Hypotension; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Pulmonary Edema; Quinacrine; Rats; Rats, Sprague-Dawley; Vasoconstriction; Verapamil

1995
Differences in the acute actions of sGnRH and cGnRH-II on gonadotropin release in goldfish pituitary cells.
    General and comparative endocrinology, 1995, Volume: 100, Issue:3

    Topics: Acetophenones; Analysis of Variance; Animals; Calcium Channel Blockers; Cells, Cultured; Enzyme Inhibitors; Female; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins; Male; Masoprocol; Pituitary Gland; Quinacrine; Verapamil

1995
Differential effects of maitotoxin on calcium entry and ciliary beating in the rabbit ciliated tracheal epithelium.
    Biology of the cell, 1995, Volume: 85, Issue:2-3

    Topics: Animals; Arachidonic Acids; Biological Transport, Active; Bradykinin; Calcium; Calcium Channel Blockers; Chelating Agents; Cilia; Cyclic AMP; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Inhibitors; Epithelium; Indomethacin; Inositol Phosphates; Ionomycin; Kinetics; Lipoxygenase Inhibitors; Marine Toxins; Masoprocol; Motion; Oxocins; Phospholipases A; Quinacrine; Rabbits; Signal Transduction; Stimulation, Chemical; Terpenes; Thapsigargin; Trachea; Trifluoperazine; Verapamil

1995
Involvement of phospholipase A2 in gentamicin-induced rat mesangial cell activation.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2

    Topics: Acetates; Animals; Aristolochic Acids; Cell Division; Cell Survival; Cells, Cultured; Dinoprostone; Diterpenes; DNA; Enzyme Inhibitors; Gentamicins; Ginkgolides; Glomerular Mesangium; Kinetics; Lactones; Phenanthrenes; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinacrine; Rats; Rats, Wistar; Thymidine; Verapamil

1997
Organic cation transport in rat choroid plexus cells studied by fluorescence microscopy.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Animals; Animals, Newborn; Biological Transport; Cations; Choroid Plexus; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Monensin; Neurons; Potassium Cyanide; Quinacrine; Rats; Rats, Inbred F344; Tetraethylammonium; Verapamil; Video Recording

1999
Specificity of synergistic coronary flow enhancement by adenosine and pulsatile perfusion in the dog.
    The Journal of physiology, 1999, Oct-01, Volume: 520 Pt 1

    Topics: Adenosine; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Diastole; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Myocardium; Oxygen Consumption; Perfusion; Pinacidil; Quinacrine; Systole; Vasodilator Agents; Verapamil

1999
Evidence that release of adenosine triphosphate from endothelial cells during increased shear stress is vesicular.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:6

    Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Cells, Cultured; Endothelium, Vascular; Ethylmaleimide; Exocytosis; Glyburide; Humans; Infant, Newborn; Kinetics; Microscopy, Fluorescence; Monensin; Quinacrine; Secretory Vesicles; Stress, Mechanical; Umbilical Veins; Verapamil

2001
Effects of cholesterol on dye leakage induced by multidrug-resistance modulators from anionic liposomes.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2003, Volume: 18, Issue:1

    Topics: Acridines; Anions; Cholesterol; Coloring Agents; Detergents; Diltiazem; Drug Resistance, Multiple; Ethers; Liposomes; Octoxynol; Quinacrine; Rosaniline Dyes; Verapamil

2003
Uptake and efflux of quinacrine, a candidate for the treatment of prion diseases, at the blood-brain barrier.
    Cellular and molecular neurobiology, 2004, Volume: 24, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cation Transport Proteins; Cell Line; Cell Membrane; Cell Polarity; Cimetidine; Cyclosporine; Endothelial Cells; Fluorescein; Membrane Potentials; Mice; Prion Diseases; Quinacrine; Tetraethylammonium; Verapamil

2004
Toxicity of quinacrine can be reduced by co-administration of P-glycoprotein inhibitor in sporadic Creutzfeldt-Jakob disease.
    Cellular and molecular neurobiology, 2004, Volume: 24, Issue:6

    Topics: Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Creutzfeldt-Jakob Syndrome; Female; Humans; Male; Middle Aged; Quinacrine; Verapamil

2004
Transepithelial transport of fluorescent p-glycoprotein and MRP2 substrates by insect Malpighian tubules: confocal microscopic analysis of secreted fluid droplets.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 23

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Drosophila melanogaster; Epithelium; Fluorescent Dyes; Gryllidae; Malpighian Tubules; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Probenecid; Propionates; Quinacrine; Quinolines; Tetraethylammonium; Verapamil

2005
The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome.
    The Journal of membrane biology, 2006, Volume: 214, Issue:2

    Topics: Adult; Angiotensin I; Angiotensin II; Anticholesteremic Agents; Cholesterol; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Female; Fluvastatin; Homeostasis; Humans; Hypercholesterolemia; Indoles; Leukotriene C4; Male; Membrane Fluidity; Metabolic Syndrome; Middle Aged; Neutrophils; Pertussis Toxin; Protein Prenylation; Quinacrine; Signal Transduction; Superoxides; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

2006
The direct effect of levobupivacaine in isolated rat aorta involves lipoxygenase pathway activation and endothelial nitric oxide release.
    Anesthesia and analgesia, 2010, Feb-01, Volume: 110, Issue:2

    Topics: Anesthetics, Local; Animals; Aorta, Thoracic; Benzoquinones; Bupivacaine; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Levobupivacaine; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Chloride; Quinacrine; Rats; Rats, Sprague-Dawley; Verapamil

2010
Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs.
    The Journal of infectious diseases, 2016, Mar-01, Volume: 213, Issue:5

    Topics: Animals; Antimalarials; Biological Transport; Drug Resistance; Gene Expression Regulation; Genetic Variation; Membrane Transport Proteins; Methylene Blue; Oocytes; Plasmodium falciparum; Protozoan Proteins; Quinacrine; Verapamil; Xenopus laevis

2016