quinacrine and trifluoperazine

quinacrine has been researched along with trifluoperazine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199022 (64.71)18.7374
1990's6 (17.65)18.2507
2000's2 (5.88)29.6817
2010's3 (8.82)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Pajeva, I; Wiese, M1
Chen, IL; Chen, YL; Lu, CM; Tsao, LT; Wang, JP1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Dos Santos, JL; Fernandes, BC; Fernandes, GFDS; Valente, V1
Erb, L; Hicks-Taylor, CS; Landis, DM; Lustig, KD; Sportiello, MG; Weisman, GA; Zhang, X1
Ichikawa, M; Matsumoto, G; Urayama, M1
Anderson, RA; Bielfeld, P; Feathergill, KA; Johnson, SK; Zaneveld, LJ1
Pastuszko, A; Wilson, DF1
Gandhi, VC; Jones, DJ1
Bjerregaard, HF1
Das, DK; Jones, RM; Otani, H; Prasad, MR1
Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG1
Bentley, PJ; Hazard, RL; McGahan, MC1
Schaeffer, BE; Zadunaisky, JA1
Cooper, CL; Malik, KU1
Danon, A; Davis, BB; Thomasson, DL; Zenser, TV1
Grollman, EF; Luini, A; Marcocci, C; Santisteban, P1
Metz, SA1
Nakagawa, Y; Waku, K1
Lang, F; Rehwald, W1
Cooper, CL; Malik, KU; Shaffer, JE1
Folkert, VW; Schlondorff, D1
Bentley, PJ; McGahan, MC1
Homma, Y; Nagai, Y; Takenawa, T2
Folkert, VW; Schlondorff, D; Yunis, M1
Feinstein, MB; Opas, EE; Walenga, RW1
Dazy, AC; Diogène, G; Marano, F; Venant, A1
Kristufek, D; Kubicek, CP; Mach, RL; Zeilinger, S1
Bensalem, J; Bryksin, V; Fourrier, C; Hattersley, K; Hein, LK; Sargeant, TJ1

Reviews

1 review(s) available for quinacrine and trifluoperazine

ArticleYear
Recent advances in the discovery of small molecules targeting glioblastoma.
    European journal of medicinal chemistry, 2019, Feb-15, Volume: 164

    Topics: Animals; Central Nervous System Neoplasms; Drug Discovery; Glioblastoma; Humans; Neoplastic Stem Cells

2019

Other Studies

33 other study(ies) available for quinacrine and trifluoperazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured

1998
Synthesis and antiinflammatory evaluation of 9-anilinoacridine and 9-phenoxyacridine derivatives.
    Journal of medicinal chemistry, 2002, Oct-10, Volume: 45, Issue:21

    Topics: Acridines; Amsacrine; Aniline Compounds; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Degranulation; Cells, Cultured; Drug Screening Assays, Antitumor; Humans; Macrophages; Mast Cells; Mice; Neutrophils; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2002
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Mechanisms by which extracellular ATP and UTP stimulate the release of prostacyclin from bovine pulmonary artery endothelial cells.
    Biochimica et biophysica acta, 1992, Feb-19, Volume: 1134, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Cattle; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; Lipid Metabolism; Phospholipases A; Phospholipases A2; Pulmonary Artery; Quinacrine; Receptors, Cell Surface; Trifluoperazine; Uridine Triphosphate

1992
Anticalmodulin drugs block the sodium gating current of squid giant axons.
    The Journal of membrane biology, 1991, Volume: 120, Issue:3

    Topics: Animals; Axons; Biological Transport, Active; Calmodulin; Chlorpromazine; Decapodiformes; Diazepam; Imidazoles; Ion Channel Gating; Membrane Potentials; Phenothiazines; Potassium; Quinacrine; Sodium; Sulfonamides; Trifluoperazine

1991
Characterization and inhibitor sensitivity of human sperm phospholipase A2: evidence against pivotal involvement of phospholipase A2 in the acrosome reaction.
    Molecular reproduction and development, 1990, Volume: 27, Issue:4

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Acetophenones; Acrosome; Adult; Calcium; Deoxycholic Acid; Dimethyl Sulfoxide; Humans; Hydrogen-Ion Concentration; Kinetics; Lysophosphatidylcholines; Male; Phospholipases A; Phospholipases A2; Quinacrine; Spermatozoa; Temperature; Trifluoperazine

1990
Kainate-induced uptake of calcium by synaptosomes from rat brain.
    FEBS letters, 1985, Nov-11, Volume: 192, Issue:1

    Topics: Animals; Brain; Calcium; Cobalt; Ion Channels; Kainic Acid; Kinetics; Male; Potassium; Quinacrine; Rats; Rats, Inbred Strains; Synaptosomes; Trifluoperazine

1985
Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Kinetics; Male; Nifedipine; Nitrendipine; Quinacrine; Rats; Rats, Inbred Strains; Spinal Cord; Trifluoperazine; Verapamil

1988
Mechanism of calcium ionophore stimulated Cl secretion from frog skin glands.
    Pflugers Archiv : European journal of physiology, 1989, Volume: 414, Issue:2

    Topics: Amiloride; Animals; Calcimycin; Chlorides; Female; Indomethacin; Ion Channels; Male; Nervous System Physiological Phenomena; Potassium; Quinacrine; Rana esculenta; Skin; Sodium; Stimulation, Chemical; Tetrodotoxin; Trifluoperazine

1989
Mechanism of membrane phospholipid degradation in ischemic-reperfused rat hearts.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Coronary Disease; Fatty Acids, Nonesterified; Glycerol; Male; Membrane Lipids; Myocardial Reperfusion; Myocardium; Phospholipids; Quinacrine; Rats; Rats, Inbred Strains; Trifluoperazine; Verapamil

1989
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria.
    Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2

    Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil

1989
Melittin-induced changes in Na and Cl movements across the skin and cornea (in vitro) of the toad Bufo marinus.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 82, Issue:2

    Topics: Amphotericin B; Animals; Bee Venoms; Biological Transport, Active; Bufo marinus; Bumetanide; Chlorides; Cornea; Meclofenamic Acid; Melitten; Quinacrine; Skin; Sodium; Trifluoperazine; Vasopressins

1985
Mechanism for leukotriene C4 stimulation of chloride transport in cornea.
    The Journal of membrane biology, 1986, Volume: 93, Issue:3

    Topics: Animals; Biological Transport, Active; Chlorides; Cornea; Cyclic AMP; Dinoprostone; Endothelium; Epithelium; Indomethacin; Kinetics; Prostaglandins E; Quinacrine; Ranidae; SRS-A; Trifluoperazine

1986
Contribution of Ca++ and calmodulin to the action of norepinephrine on renal prostaglandin synthesis and vascular tone.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Calcium; Calcium Channel Blockers; Calmodulin; Indomethacin; Kidney; Male; Norepinephrine; Perfusion; Prazosin; Prostaglandins; Quinacrine; Rats; Rats, Inbred Strains; Trifluoperazine; Vasoconstriction

1986
Effect of verapamil on prostaglandin E2 synthesis by hydronephrotic rabbit cortical interstitial cells in primary culture.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Diltiazem; Dinoprostone; Dose-Response Relationship, Drug; Hydronephrosis; Kidney Cortex; Magnesium; Male; Nifedipine; Prostaglandins E; Quinacrine; Rabbits; Trifluoperazine; Verapamil

1986
Norepinephrine and thyrotropin stimulation of iodide efflux in FRTL-5 thyroid cells involves metabolites of arachidonic acid and is associated with the iodination of thyroglobulin.
    Endocrinology, 1987, Volume: 120, Issue:3

    Topics: Animals; Arachidonic Acids; Calcimycin; Calcium; Cell Line; Iodides; Kinetics; Norepinephrine; Quinacrine; Rats; Thyroglobulin; Thyroid Gland; Thyrotropin; Trifluoperazine

1987
Exogenous arachidonic acid promotes insulin release from intact or permeabilized rat islets by dual mechanisms. Putative activation of Ca2+ mobilization and protein kinase C.
    Diabetes, 1988, Volume: 37, Issue:11

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Radioisotopes; Cell Membrane Permeability; Cold Temperature; Dantrolene; Digitonin; Drug Synergism; Enzyme Activation; Ethers; Glucose; Insulin; Insulin Secretion; Ionomycin; Islets of Langerhans; Kinetics; Protein Kinase C; Quinacrine; Rats; Sodium; Tetradecanoylphorbol Acetate; Trifluoperazine

1988
Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists.
    Biochemical and biophysical research communications, 1988, Oct-31, Volume: 156, Issue:2

    Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Calmodulin; Chlorpromazine; Chromatography, High Pressure Liquid; Cytochalasin B; Linoleic Acid; Linoleic Acids; Macrophage Activation; Macrophages; Oleic Acid; Oleic Acids; Opsonin Proteins; Phosphatidylcholines; Phosphatidylinositols; Phospholipases A; Pulmonary Alveoli; Quinacrine; Rabbits; Sulfonamides; Trifluoperazine; Zymosan

1988
On the nature of delayed repolarization during sustained sodium coupled transport in frog proximal tubules.
    Pflugers Archiv : European journal of physiology, 1987, Volume: 410, Issue:4-5

    Topics: Animals; In Vitro Techniques; Indomethacin; Kidney Tubules, Proximal; Membrane Potentials; Microelectrodes; Perfusion; Phenylalanine; Quinacrine; Rana esculenta; Sodium; Trifluoperazine

1987
Mechanism of action of angiotensin II and bradykinin on prostaglandin synthesis and vascular tone in the isolated rat kidney. Effect of Ca++ antagonists and calmodulin inhibitors.
    Circulation research, 1985, Volume: 56, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Bradykinin; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Dantrolene; Diltiazem; Dinoprostone; Gallic Acid; Imidazoles; Indomethacin; Kidney; Male; Nicotinic Acids; Nimodipine; Prostaglandins E; Quinacrine; Rats; Rats, Inbred Strains; Ryanodine; Stimulation, Chemical; Sulfonamides; Trifluoperazine; Vasoconstriction

1985
Relationship between prostaglandin synthesis and phospholipid turnover in rat glomeruli: effect of trifluoperazine, A23187, and mepacrine.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 11

    Topics: Animals; Anti-Bacterial Agents; Calcimycin; Carbon Radioisotopes; Dinoprost; Dinoprostone; Kidney Glomerulus; Kinetics; Phospholipids; Prostaglandins; Prostaglandins E; Prostaglandins F; Quinacrine; Rats; Trifluoperazine

1983
A pharmacological analysis of chloride transport across the amphibian cornea.
    The Journal of physiology, 1982, Volume: 325

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport, Active; Bucladesine; Bufo marinus; Bumetanide; Calcimycin; Chlorides; Cornea; Dinoprostone; Epinephrine; In Vitro Techniques; Meclofenamic Acid; Models, Biological; Prostaglandins E; Quinacrine; Trifluoperazine

1982
Role of Ca2+ in phosphatidylinositol response and arachidonic acid release in formylated tripeptide- or Ca2+ ionophore A23187-stimulated guinea pig neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 130, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Female; Guinea Pigs; Lysophospholipids; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphatidylinositols; Phospholipids; Phosphorus Radioisotopes; Quinacrine; Trifluoperazine

1983
Prostaglandin synthesis linked to phosphatidylinositol turnover in isolated rat glomeruli.
    Biochimica et biophysica acta, 1984, Jul-06, Volume: 794, Issue:2

    Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dose-Response Relationship, Drug; Kidney Glomerulus; Male; Phosphates; Phosphatidylinositols; Prostaglandins; Quinacrine; Radioimmunoassay; Rats; Rats, Inbred Strains; Trifluoperazine

1984
Differential effects of calmodulin antagonists on phospholipases A2 and C in thrombin-stimulated platelets.
    The Journal of biological chemistry, 1981, Dec-10, Volume: 256, Issue:23

    Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Dibucaine; Fluphenazine; Humans; Kinetics; Phospholipases; Phospholipases A; Phospholipids; Platelet Aggregation; Quinacrine; Thrombin; Trifluoperazine; Type C Phospholipases

1981
Effect of calmodulin antagonists on lysosomal enzyme secretion and phospholipid metabolism in guinea-pig macrophages.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Acetylglucosaminidase; Animals; Arachidonic Acid; Arachidonic Acids; Calcium-Binding Proteins; Calmodulin; Dibucaine; Female; Guinea Pigs; Hexosaminidases; In Vitro Techniques; Lysosomes; Macrophages; Phospholipids; Quinacrine; Trifluoperazine; Triglycerides

1982
Differential effects of maitotoxin on calcium entry and ciliary beating in the rabbit ciliated tracheal epithelium.
    Biology of the cell, 1995, Volume: 85, Issue:2-3

    Topics: Animals; Arachidonic Acids; Biological Transport, Active; Bradykinin; Calcium; Calcium Channel Blockers; Chelating Agents; Cilia; Cyclic AMP; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Inhibitors; Epithelium; Indomethacin; Inositol Phosphates; Ionomycin; Kinetics; Lipoxygenase Inhibitors; Marine Toxins; Masoprocol; Motion; Oxocins; Phospholipases A; Quinacrine; Rabbits; Signal Transduction; Stimulation, Chemical; Terpenes; Thapsigargin; Trachea; Trifluoperazine; Verapamil

1995
Ca2+-calmodulin antagonists interfere with xylanase formation and secretion in Trichoderma reesei.
    Biochimica et biophysica acta, 1998, Jul-24, Volume: 1403, Issue:3

    Topics: Calcimycin; Calcium; Calmodulin; Chelating Agents; Chlorpromazine; Egtazic Acid; Ionophores; Lanthanum; Protein Kinases; Quinacrine; Subcellular Fractions; Transcription, Genetic; Trichoderma; Trifluoperazine; Xylan Endo-1,3-beta-Xylosidase; Xylosidases

1998
Comparison of chloroquine-like molecules for lysosomal inhibition and measurement of autophagic flux in the brain.
    Biochemical and biophysical research communications, 2021, 01-01, Volume: 534

    Topics: Animals; Autophagy; Brain; Chloroquine; Drug Evaluation, Preclinical; Female; HeLa Cells; Humans; Lysosomes; Macrolides; Male; Mefloquine; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Promazine; Quinacrine; Trifluoperazine

2021