quinacrine and quinidine

quinacrine has been researched along with quinidine in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199025 (55.56)18.7374
1990's3 (6.67)18.2507
2000's11 (24.44)29.6817
2010's6 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Galanakis, D; Ganellin, CR1
Chen, X; Chong, CR; Liu, JO; Shi, L; Sullivan, DJ1
Harada, S; Huy, NT; Kamei, K; Maeda, A; Oida, T; Trang, DT; Uyen, DT1
Acharya, BN; Kaushik, MP; Saraswat, D1
Lombardo, F; Obach, RS; Waters, NJ1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Doh-Ura, K; Go, ML; Nguyen, T; Sakasegawa, Y1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Juan, H1
Boesch, D; Loor, F; Muller, K; Pourtier-Manzanedo, A1
Kehl, SJ1
Fehlau, R; Fuhrmann, GF; Knauf, PA; Schneider, H1
Cragoe, EJ; Jones, LR; Seiler, SM1
Holmes, J; Sapeika, N; Zwarenstein, H2
Almeyda, J; Levantine, A1
Goodman, HM; Schimmel, RJ1
Fain, JN; Pointer, RH1
Mason, RG; Read, MS; Saba, SR; Shermer, RW1
Ball, EG; Markus, HB1
Molinengo, L1
Jones, MT; Sideropoulos, AS; Specht, SM1
Bennett, T; Lot, TY1
Imanishi, S; Miyamae, S1
FERRARI, M1
KURNICK, NB; RADCLIFFE, IE1
MELVILLE, KI; VARMA, DR1
ARORA, RB; LAL, A1
MAEKAWA, M; NOHARA, Y1
CROSBY, WH; KAUFMAN, RM1
DIXON, JK1
McMILLAN, RL; ROSENBLUM, M; YOUNT, EH1
SCHAFFER, AI1
Emerson, LR; Kuchler, K; Skillman, BC; Wirth, DF; Wolfger, H1
EATON, CH; HILL, RL1
Almeida, GT; Corrêa Soares, JB; Egan, TJ; Ferreira-Pereira, A; Hunter, R; Kuter, D; Menezes, D; Oliveira, MF; Vannier-Santos, MA; Venancio, TM; Verjovski-Almeida, S; Zishiri, VK1

Reviews

1 review(s) available for quinacrine and quinidine

ArticleYear
Drug reactions. XVI. Lichenoid drug eruptions.
    The British journal of dermatology, 1971, Volume: 85, Issue:6

    Topics: Aminosalicylic Acids; Aniline Compounds; Arsphenamine; Chlorothiazide; Chlorpropamide; Dermatitis, Exfoliative; Gold; Humans; Hydrochlorothiazide; Lichen Planus; Methyldopa; Phenothiazines; Phenylbutazone; Quinacrine; Quinidine; Tetracycline; Thiazoles

1971

Other Studies

44 other study(ies) available for quinacrine and quinidine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.
    Bioorganic & medicinal chemistry letters, 2004, Aug-02, Volume: 14, Issue:15

    Topics: Animals; Apamin; Guinea Pigs; Hepatocytes; Kinetics; Molecular Conformation; Potassium Channels, Calcium-Activated

2004
A clinical drug library screen identifies astemizole as an antimalarial agent.
    Nature chemical biology, 2006, Volume: 2, Issue:8

    Topics: Animals; Antimalarials; Astemizole; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Drug Resistance, Multiple; Humans; Mice; Plasmodium falciparum; Plasmodium yoelii

2006
Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Animals; Antimalarials; Colorimetry; Crystallization; Drug Evaluation, Preclinical; Heme; Hemeproteins; Plasmodium falciparum; Polysorbates; Reproducibility of Results

2007
Pharmacophore based discovery of potential antimalarial agent targeting haem detoxification pathway.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:12

    Topics: Animals; Antimalarials; Drug Discovery; Heme; Isoniazid; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Stereoisomerism

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

    Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Anti-prion activities and drug-like potential of functionalized quinacrine analogs with basic phenyl residues at the 9-amino position.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Blood-Brain Barrier; Cell Line, Tumor; Dogs; Humans; Madin Darby Canine Kidney Cells; Mice; Peptide Fragments; Permeability; Piperazines; Piperidines; Prion Diseases; Prions; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship

2011
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Inhibition of the algesic effect of bradykinin and acetylcholine by mepacrine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 301, Issue:1

    Topics: Acetylcholine; Animals; Bradykinin; Female; Male; Pain; Prostaglandins E; Quinacrine; Quinidine; Rabbits; Time Factors; Vasoconstriction

1977
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative.
    Experimental cell research, 1991, Volume: 196, Issue:1

    Topics: Amiodarone; Animals; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Flow Cytometry; Leukemia, Experimental; Leukemia, Myeloid; Microscopy, Fluorescence; Quinacrine; Quinidine; Tumor Cells, Cultured; Verapamil

1991
Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs.
    British journal of pharmacology, 1991, Volume: 103, Issue:3

    Topics: Animals; Electrodes; Hydrogen-Ion Concentration; Male; Membrane Potentials; Pituitary Gland; Potassium Channels; Quinacrine; Quinidine; Rats; Rats, Inbred Strains

1991
The effect of ferricyanide with iodoacetate in calcium-free solution on passive cation permeability in human red blood cells: comparison with the Gardos-effect and with the influence of PCMBS on passive cation permeability.
    Biochimica et biophysica acta, 1989, Aug-07, Volume: 983, Issue:2

    Topics: 4-Chloromercuribenzenesulfonate; Calcimycin; Calcium; Cell Membrane Permeability; Erythrocyte Membrane; Ferricyanides; Humans; Iodoacetates; Iodoacetic Acid; Phenylmercury Compounds; Potassium Channels; Quinacrine; Quinidine; Sodium Channels; Solutions; Vanadates

1989
Demonstration of a Na+/H+ exchange activity in purified canine cardiac sarcolemmal vesicles.
    The Journal of biological chemistry, 1985, Apr-25, Volume: 260, Issue:8

    Topics: Alamethicin; Animals; Carrier Proteins; Dogs; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Myocardium; Quinacrine; Quinidine; Quinuclidinyl Benzilate; Sarcolemma; Sodium; Sodium-Hydrogen Exchangers; Subcellular Fractions

1985
Effect of quinoline, phthalazine and coumarin derivatives on the absorbance of NADPH.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1

    Topics: Chloroquine; Coumarins; Heterocyclic Compounds; Hydralazine; Indophenol; NADP; Novobiocin; Quinacrine; Quinidine; Quinine; Quinolines; Spectrophotometry; Warfarin

1974
Release of pre-formed free fatty acids from adipose tissue: acceleration by cyclic AMP.
    Endocrinology, 1972, Volume: 90, Issue:5

    Topics: Adipose Tissue; Animals; Butyrates; Culture Media; Cyclic AMP; Depression, Chemical; Drug Synergism; Epididymis; Epinephrine; Fatty Acids, Nonesterified; Hypophysectomy; In Vitro Techniques; Insulin; Male; Pituitary Gland; Quinacrine; Quinidine; Rats; Stimulation, Chemical; Theophylline

1972
Response of isolated white fat cells to anti-malarial drugs.
    Biochemical pharmacology, 1973, Dec-01, Volume: 22, Issue:23

    Topics: Adenylyl Cyclase Inhibitors; Adipose Tissue; Animals; Antimalarials; Bucladesine; Chloroquine; Drug Synergism; Fatty Acids, Nonesterified; Female; Glycerol; Norepinephrine; Primaquine; Proteins; Quinacrine; Quinidine; Rats; Theophylline; Triglycerides

1973
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts

1973
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
    Thrombosis et diathesis haemorrhagica, 1972, Feb-29, Volume: 27, Issue:1

    Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds

1972
Inhibition of lipolytic processes in rat adipose tissue by antimalaria drugs.
    Biochimica et biophysica acta, 1969, Dec-17, Volume: 187, Issue:4

    Topics: Adipose Tissue; Animals; Antimalarials; Chloroquine; Epididymis; Fatty Acids; Heparin; Hydroxychloroquine; Lipid Metabolism; Male; Primaquine; Quinacrine; Quinidine; Quinine; Rats

1969
On the pharmacological inhibition of epinephrine-induced ventricular automaticity.
    European journal of pharmacology, 1968, Volume: 5, Issue:1

    Topics: Acetanilides; Acetylcholine; Animals; Atropine; Benzoates; Emetine; Ephedrine; Epinephrine; Heart; Heart Ventricles; In Vitro Techniques; Male; Methanol; Muscle Contraction; Muscle, Smooth; Procainamide; Quinacrine; Quinidine; Rats; Secologanin Tryptamine Alkaloids; Solubility; Sympatholytics; Urethane; Ventricular Fibrillation

1968
Feasibility of testing DNA repair inhibitors for mutagenicity by a simple method.
    Mutation research, 1980, Volume: 74, Issue:2

    Topics: Depression, Chemical; DNA; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Escherichia coli; Genetic Techniques; Quinacrine; Quinidine; Quinine; Ultraviolet Rays

1980
Comparison of the effects of chloroquine quinacrine and quinidine on autonomic neuroeffector mechanisms.
    Medical biology, 1982, Volume: 60, Issue:6

    Topics: Animals; Autonomic Nervous System; Chickens; Chloroquine; Electric Stimulation; Female; Indomethacin; Male; Mice; Norepinephrine; Quinacrine; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Tetrodotoxin

1982
Hyperpolarization induced by sodium removal in rabbit sinoatrial node cells. Possible role of electrogenic sodium-calcium exchange.
    Journal of electrocardiology, 1995, Volume: 28, Issue:2

    Topics: Animals; Calcium; In Vitro Techniques; Lidocaine; Membrane Potentials; Ouabain; Quinacrine; Quinidine; Rabbits; Sinoatrial Node; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil

1995
[Clinical notes on quinidine therapy].
    Giornale di clinica medica, 1959, Volume: 40

    Topics: Anti-Arrhythmia Agents; Enzyme Inhibitors; Heart Diseases; Quinacrine; Quinidine

1959
Reaction between DNA and quinacrine and other antimalarials.
    The Journal of laboratory and clinical medicine, 1962, Volume: 60

    Topics: Antimalarials; Chloroquine; DNA; Quinacrine; Quinidine; Quinine

1962
Ventricular fibrillation induced by coronary occlusion during hypothermia in dogs and the effects of quinidine, quinacrine, and oxytocin.
    Canadian journal of biochemistry and physiology, 1963, Volume: 41

    Topics: Animals; Coronary Disease; Coronary Occlusion; Dogs; Hypothermia; Hypothermia, Induced; Oxytocin; Quinacrine; Quinidine; Ventricular Fibrillation

1963
ANTIMALARIAL DRUGS ON THE AUTOMATICITY OF SINO-AURICULAR AND ATRIO-VENTRICULAR NODES.
    The Indian journal of medical research, 1963, Volume: 51

    Topics: Administration, Intravenous; Amodiaquine; Animals; Anti-Arrhythmia Agents; Antimalarials; Atrioventricular Node; Atropine; Chloroquine; Dogs; Heart Conduction System; Humans; Hydroxychloroquine; Hypotension; Injections, Intravenous; Primaquine; Quinacrine; Quinidine; Research; Statistics as Topic

1963
[DRUGS FOR TREATING ARRHYTHMIA].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Arrhythmias, Cardiac; Chlorpromazine; Digitalis Glycosides; Humans; Pharmacology; Potassium; Procainamide; Quinacrine; Quinidine; Reserpine

1963
DRUG-INDUCED THROMBOCYTOPENIA.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Acetazolamide; Anticonvulsants; Arsphenamine; Chloramphenicol; Chlorothiazide; Colchicine; Gold; Hydantoins; Hypoglycemic Agents; Meprobamate; Perchlorates; Phenothiazines; Phenylbutazone; Pyrimethamine; Quinacrine; Quinidine; Quinine; Ristocetin; Streptomycin; Sulfonamides; Thrombocytopenia; Toxicology

1964
REFRACTORY VENTRICULAR TACHYCARDIA: REPORT OF A PATIENT SUCCESSFULLY TREATED WITH HIGH DOSES OF QUINIDINE INTRAVENOUSLY.
    Southern medical journal, 1964, Volume: 57

    Topics: Black People; Digitalis; Electrocardiography; Norepinephrine; Oxygen Inhalation Therapy; Procainamide; Quinacrine; Quinidine; Tachycardia; Tachycardia, Ventricular

1964
Use of quinidine in treatment of chronic auricular fibrillation; results obtained in a series of one hundred fifty-five patients.
    A.M.A. archives of internal medicine, 1952, Volume: 89, Issue:1

    Topics: Atrial Fibrillation; Quinacrine; Quinidine

1952
Procaine amide compared with quinidine as a therapy for arrhythmias.
    American heart journal, 1951, Volume: 42, Issue:4

    Topics: Arrhythmias, Cardiac; Humans; Procainamide; Procaine; Quinacrine; Quinidine

1951
The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.
    Annals of tropical medicine and parasitology, 2004, Volume: 98, Issue:6

    Topics: Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Cycloheximide; Drug Resistance, Multiple, Fungal; Gene Deletion; Genes, Fungal; Mefloquine; Mutation; Quinacrine; Quinidine; Quinine; Saccharomyces cerevisiae; Transcription, Genetic

2004
Atabrine in the treatment of cardiac arrhythmias.
    United States Armed Forces medical journal, 1950, Volume: 1, Issue:5

    Topics: Arrhythmias, Cardiac; Quinacrine; Quinidine

1950
Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.
    PLoS neglected tropical diseases, 2009, Jul-14, Volume: 3, Issue:7

    Topics: Animals; Anthelmintics; Female; Gastrointestinal Tract; Gene Expression Profiling; Hemeproteins; Intestinal Mucosa; Liver; Male; Mice; Parasite Egg Count; Quinacrine; Quinidine; Quinine; Schistosoma mansoni; Schistosomiasis mansoni

2009