quinacrine and proadifen

quinacrine has been researched along with proadifen in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's5 (35.71)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Dalvie, D; Hu, Q; Jones, P; Obach, RS; Pryde, DC; Tran, TD1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
DiPaola, M; Kao, PN; Karlin, A1
Harbison, RG; Ignarro, LJ; Kadowitz, PJ; Wood, KS1
Fiera, RA; Matthews, N; Neale, ML1
Ioannides, C; Lewis, DF; Parke, DV1
Nichol, AW1
Kaldany, RR; Karlin, A1
Gustafsson, JA; Hamberg, M; Mode, A; Tollet, P1
Sakuta, H; Yoneda, I1
Lavallée, M; Ming, Z; Parent, R1
Calders, P; Van de Voorde, J; Van den Bossche, I; Vanheel, B1
Barrantes, GE; Ortells, MO1

Other Studies

14 other study(ies) available for quinacrine and proadifen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Aldehyde oxidase: an enzyme of emerging importance in drug discovery.
    Journal of medicinal chemistry, 2010, Dec-23, Volume: 53, Issue:24

    Topics: Aldehyde Oxidase; Animals; Drug Discovery; Humans; Models, Molecular; Organ Specificity; Oxidation-Reduction; Pharmaceutical Preparations; Pharmacokinetics; Species Specificity; Substrate Specificity

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Mapping the alpha-subunit site photolabeled by the noncompetitive inhibitor [3H]quinacrine azide in the active state of the nicotinic acetylcholine receptor.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Acetylcholine; Affinity Labels; Amino Acid Sequence; Amphibian Venoms; Animals; Azides; Binding Sites; Bupivacaine; Chlorpromazine; Chromatography, High Pressure Liquid; Cyanogen Bromide; Molecular Sequence Data; Molecular Weight; Nicotinic Antagonists; Peptide Fragments; Peptide Mapping; Photochemistry; Proadifen; Quinacrine; Receptors, Nicotinic; Torpedo

1990
Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Bradykinin; Cattle; Endothelium; Enzyme Activation; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Methylene Blue; Nitric Oxide; Proadifen; Pulmonary Artery; Pulmonary Veins; Quinacrine; Solubility; Vasodilator Agents

1986
Involvement of phospholipase A2 activation in tumour cell killing by tumour necrosis factor.
    Immunology, 1988, Volume: 64, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonic Acids; Cell Survival; Dexamethasone; Humans; Indomethacin; Phospholipases; Phospholipases A; Phospholipases A2; Proadifen; Pyrazoles; Quinacrine; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1988
Molecular dimensions of the substrate binding site of cytochrome P-448.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Animals; Binding Sites; Computers; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochromes; Ellipticines; Enzyme Induction; Hydroxylation; Metyrapone; Models, Molecular; Proadifen; Protein Conformation; Quinacrine; Substrate Specificity

1986
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
    Biochimica et biophysica acta, 1970, Oct-27, Volume: 222, Issue:1

    Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles

1970
Reaction of quinacrine mustard with the acetylcholine receptor from Torpedo californica.
    The Journal of biological chemistry, 1983, May-25, Volume: 258, Issue:10

    Topics: Animals; Carbachol; Cell Membrane Permeability; Cobra Neurotoxin Proteins; Electric Organ; Ion Channels; Proadifen; Quinacrine; Quinacrine Mustard; Radioisotopes; Receptors, Cholinergic; Rubidium; Torpedo; Tritium; Tubocurarine

1983
Growth hormone signaling leading to CYP2C12 gene expression in rat hepatocytes involves phospholipase A2.
    The Journal of biological chemistry, 1995, May-26, Volume: 270, Issue:21

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Diglycerides; Enzyme Activation; Gene Expression Regulation; Growth Hormone; Insulin-Like Growth Factor I; Ketoconazole; Lactams, Macrocyclic; Liver; Phospholipases A; Phospholipases A2; Phospholipids; Phosphorylation; Proadifen; Protein-Tyrosine Kinases; Quinacrine; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Verapamil

1995
Inhibition by SKF 525A and quinacrine of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes.
    European journal of pharmacology, 1994, Jan-24, Volume: 252, Issue:1

    Topics: Animals; Benzopyrans; Cromakalim; Cytochrome P-450 Enzyme Inhibitors; Glyburide; Oocytes; Phospholipases A; Phospholipases A2; Potassium Channels; Proadifen; Pyrroles; Quinacrine; Xenopus laevis

1994
Nitric oxide-independent dilation of conductance coronary arteries to acetylcholine in conscious dogs.
    Circulation research, 1997, Volume: 81, Issue:6

    Topics: Acetylcholine; Adenosine; Animals; Aspirin; Coronary Circulation; Coronary Vessels; Dogs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proadifen; Quinacrine; Vasodilation

1997
Influence of some phospholipase A2 and cytochrome P450 inhibitors on rat arterial smooth muscle K+ currents.
    Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:7

    Topics: Animals; Calcium; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; Miconazole; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Potassium Channels; Proadifen; Quinacrine; Rats

1999
Understanding channel blocking in the nicotinic acetylcholine receptor.
    Receptors & channels, 2001, Volume: 7, Issue:4

    Topics: Acetylcholine; Animals; Binding Sites; Chlorisondamine; Ethidium; Hexamethonium; Lidocaine; Mice; Nicotinic Antagonists; Onium Compounds; Pempidine; Proadifen; Quinacrine; Receptors, Nicotinic; Trityl Compounds

2001