quinacrine and mitoxantrone

quinacrine has been researched along with mitoxantrone in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Denny, WA; Feigon, J; Kearns, DR; Leupin, W1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cechinel Filho, V; Corrêa, R; Klein-Júnior, LC; Vander Heyden, Y1
Darzynkiewicz, Z; Kapuscinski, J1
Bjermer, L; Eksborg, S; Gruber, A; Henriksson, R; Sandström, T; Sue-Chu, M1
Agarwal, R; Shaw, P1
Field, RA; Maxwell, A; Mitchenall, LA; Rejzek, M; Taylor, JA1
Agarwal, R; Shaw, PH1
Al-Mugotir, M; Bessho, M; Bessho, T; Borgstahl, GEO; George, J; Kolar, C; Lovelace, JJ; Natarajan, A; Pal, D; Rana, S; Struble, L1

Reviews

3 review(s) available for quinacrine and mitoxantrone

ArticleYear
All that glitters is not gold: Panning cytotoxic natural products and derivatives with a fused tricyclic backbone by the estimation of their leadlikeness for cancer treatment.
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Antineoplastic Agents; Biological Products; Chemical Phenomena; Humans; Macrocyclic Compounds

2019
Pleurodesis for malignant pleural effusions.
    The Cochrane database of systematic reviews, 2004, Issue:1

    Topics: Humans; Mitoxantrone; Pleural Effusion, Malignant; Pleurodesis; Propionibacterium acnes; Quinacrine; Randomized Controlled Trials as Topic; Sclerosing Solutions; Talc; Tetracycline

2004
WITHDRAWN: Pleurodesis for malignant pleural effusions.
    The Cochrane database of systematic reviews, 2013, Nov-20, Issue:11

    Topics: Humans; Mitoxantrone; Pleural Effusion, Malignant; Pleurodesis; Propionibacterium acnes; Quinacrine; Randomized Controlled Trials as Topic; Sclerosing Solutions; Talc; Tetracycline

2013

Trials

1 trial(s) available for quinacrine and mitoxantrone

ArticleYear
Effects of intrapleural mitoxantrone and mepacrine on malignant pleural effusion--a randomised study.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:13-14

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fever; Humans; Male; Middle Aged; Mitoxantrone; Pain; Pleural Effusion, Malignant; Quality of Life; Quinacrine; Radiography; Remission Induction; Suction; Survival Rate

1995

Other Studies

8 other study(ies) available for quinacrine and mitoxantrone

ArticleYear
Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Antineoplastic Agents; Base Composition; Chemical Phenomena; Chemistry; DNA; Hydrogen Bonding; Intercalating Agents; Kinetics; Magnetic Resonance Spectroscopy; Structure-Activity Relationship

1984
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Condensation of DNA in situ in metaphase chromosomes induced by intercalating ligands and its relationship to chromosome banding.
    Cytometry, 1988, Volume: 9, Issue:1

    Topics: Acridine Orange; Animals; Base Sequence; Cell Line; Chromosome Banding; Chromosomes; Cricetinae; Cricetulus; DNA; Female; Intercalating Agents; Ligands; Metaphase; Microscopy, Phase-Contrast; Mitoxantrone; Ovary; Quinacrine

1988
Application of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VI.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Anthraquinones; Arabidopsis; Archaeal Proteins; DNA Topoisomerases, Type II; Drug Evaluation, Preclinical; Escherichia coli; Hexylresorcinol; Methanosarcina; Mitoxantrone; Quinacrine; Sulfolobus; Suramin; Topoisomerase II Inhibitors; Topoisomerase Inhibitors

2013
Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: Apoptosis; BRCA1 Protein; Cell Death; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; Doxorubicin; Fluorescence; High-Throughput Screening Assays; Homologous Recombination; Humans; Mitoxantrone; Neoplasms; Protein Binding; Quinacrine; Rad52 DNA Repair and Recombination Protein; Replication Protein A; Small Molecule Libraries

2021