quinacrine and methotrexate

quinacrine has been researched along with methotrexate in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's3 (23.08)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Cohen, FE; Legname, G; May, BC; Prusiner, SB; Sherrill, J; Wallace, AC; Witkop, J; Zorn, JA1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Gasc, AM; Sicard, AM1
Bennett, A; Melhuish, PB; Patel, S; Randles, H; Stamford, IF1
Craddock, CG; Crandall, BF; Hinkes, E; Weber, F1
Bertino, JR; Booth, BA; Iannotti, AT; Johns, DG; Sartorelli, AC1
Birring, S; Brex, P; Galloway, J; Larkin, G; Murgatroyd, F; Paolino, A; Patel, A; Sado, D; Walsh, S1

Reviews

1 review(s) available for quinacrine and methotrexate

ArticleYear
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020

Other Studies

12 other study(ies) available for quinacrine and methotrexate

ArticleYear
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
    Journal of medicinal chemistry, 2007, Jan-11, Volume: 50, Issue:1

    Topics: Aminopyridines; Animals; Cell Line, Tumor; Combinatorial Chemistry Techniques; Membranes, Artificial; Mice; Models, Molecular; Nitriles; Permeability; PrPSc Proteins; Solubility; Structure-Activity Relationship

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Frame-shift mutants induced by quinacrine are recognized by the mismatch repair system in Streptococcus pneumoniae.
    Molecular & general genetics : MGG, 1986, Volume: 203, Issue:2

    Topics: Base Sequence; Chromosome Deletion; DNA Repair; Drug Resistance, Microbial; Genes, Bacterial; Methotrexate; Mutation; Quinacrine; Streptococcus pneumoniae; Transformation, Bacterial

1986
Cancer in mice: effects of prednisolone or mepacrine alone and with cytotoxic drugs.
    British journal of cancer, 1987, Volume: 55, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Male; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Prednisolone; Prostaglandins E; Quinacrine; Thromboxane B2

1987
Acute leukemia with C-G chromosome translocation.
    Blood, 1973, Volume: 41, Issue:2

    Topics: Adult; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Humans; Injections, Spinal; Karyotyping; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Pedigree; Prednisone; Quinacrine; Skin; Vincristine

1973
The identity of rabbit-liver methotrexate oxidase.
    Biochimica et biophysica acta, 1965, Aug-24, Volume: 105, Issue:2

    Topics: Animals; Chloromercuribenzoates; Cyanides; Enzymes; In Vitro Techniques; Liver; Methotrexate; Oxidoreductases; Quinacrine; Rabbits; Spectrophotometry; Subcellular Fractions; Surface-Active Agents; Vitamin K

1965
Clinical phenotypes and therapeutic responses in cutaneous-predominant sarcoidosis: 6-year experience in a tertiary referral service.
    Clinical and experimental dermatology, 2021, Volume: 46, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Clinical Protocols; Dermatologic Agents; Female; Humans; Hydroxychloroquine; Interleukin-12; Interleukin-23; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Phenotype; Prospective Studies; Quinacrine; Referral and Consultation; Remission Induction; Sarcoidosis; Skin Diseases; Tertiary Care Centers; Tumor Necrosis Factor Inhibitors; Young Adult

2021