quinacrine and hydroxyurea

quinacrine has been researched along with hydroxyurea in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's1 (6.67)18.2507
2000's4 (26.67)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Palcic, B; Skarsgard, LD1
Cleaver, JE; Painter, RB1
Cristofalo, VJ; Gorman, SD1
Meneghini, R1
Kaplan, HS; Smith, KC; Town, CD1
Gaudin, D; Gregg, RS; Yielding, KL1
Fallon, RJ; Meiss, HK; Moser, GC1
Ganey, PE; Peters-Golden, M; Schiamberg, E; Tithof, PK1

Other Studies

15 other study(ies) available for quinacrine and hydroxyurea

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Absence of ultrafast processes of repair of single-strand breaks in mammalian DNA.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1975, Volume: 27, Issue:2

    Topics: Adenoviridae; Animals; Cell Line; Cells, Cultured; Cesium Isotopes; Cobalt Radioisotopes; Cricetinae; Cyanides; DNA Repair; Edetic Acid; Fibroblasts; Gamma Rays; Hot Temperature; Hydroxyurea; Iodoacetates; Mice; Oxygen; Quinacrine; Radiation Effects; Sodium

1975
Absence of specificity in inhibition of DNA repair replication by DNA-binding agents, cocarcinogens, and steroids in human cells.
    Cancer research, 1975, Volume: 35, Issue:7

    Topics: Animals; Bromodeoxyuridine; Carcinogens; Centrifugation, Density Gradient; Cyanides; Dimethyl Sulfoxide; DNA; DNA Repair; DNA Replication; Dogs; HeLa Cells; Humans; Hydroxyurea; Lymphocytes; Progesterone; Quinacrine; Radiation Effects; Thymidine; Ultraviolet Rays; Vitamin A

1975
Analysis of the G1 arrest position of senescent WI38 cells by quinacrine dihydrochloride nuclear fluorescence. Evidence for a late G1 arrest.
    Experimental cell research, 1986, Volume: 167, Issue:1

    Topics: Blood; Cell Line; Cell Nucleus; Cell Survival; Culture Media; Humans; Hydroxyurea; Interphase; Microscopy, Fluorescence; Quinacrine; Thymidine

1986
Repair replication of opossum lymphocyte DNA: effect of compounds that bind to DNA.
    Chemico-biological interactions, 1974, Volume: 8, Issue:2

    Topics: Acridines; Alkylating Agents; Animals; Autoradiography; Binding Sites; Bromodeoxyuridine; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA Repair; DNA Replication; Hydroxyurea; Kinetics; Lymphocytes; Mesylates; Opossums; Quinacrine; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays

1974
Influence of ultrafast repair processes (independent of DNA polymerase I) on the yield of DNA single-strand breaks in Escherichia coli K-12 x-irradiated in the presence of or absence of oxygen.
    Radiation research, 1972, Volume: 52, Issue:1

    Topics: Cells, Cultured; Centrifugation, Density Gradient; Cyanides; DNA Nucleotidyltransferases; DNA Repair; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Ethylmaleimide; Hydroxyurea; Iodoacetates; Oxygen; Quinacrine; Radiation Effects

1972
Inhibition of DNA repair replication by DNA binding drugs which sensitize cells to alkylating agents and X-rays.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Alkylating Agents; Caffeine; Chloroquine; Cyanides; Cyclophosphamide; Dinitrophenols; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Drug Combinations; Humans; Hydroxyurea; Injections, Intraperitoneal; Leukocyte Count; Lymphocytes; Protein Binding; Quinacrine; Quinolines; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium; Ultraviolet Rays

1972
Fluorimetric measurements and chromatin condensation patterns of nuclei from 3T3 cells throughout G1.
    Journal of cellular physiology, 1981, Volume: 106, Issue:2

    Topics: Animals; Cell Fusion; Cells, Cultured; Chromatin; Contact Inhibition; Culture Media; Hydroxyurea; Interphase; Isoleucine; Mice; Microscopy, Fluorescence; Mitosis; Quinacrine

1981
Phospholipase A2 is involved in the mechanism of activation of neutrophils by polychlorinated biphenyls.
    Environmental health perspectives, 1996, Volume: 104, Issue:1

    Topics: Animals; Arachidonic Acid; Aroclors; Aspirin; Cyclooxygenase Inhibitors; Hydroxyurea; In Vitro Techniques; Lipoxygenase Inhibitors; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phospholipases A; Phospholipases A2; Polychlorinated Biphenyls; Quinacrine; Rats; Superoxides; Terpenes; Tetradecanoylphorbol Acetate

1996