quinacrine and caffeine

quinacrine has been researched along with caffeine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's4 (12.90)18.2507
2000's8 (25.81)29.6817
2010's4 (12.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Doh-Ura, K; Go, ML; Nguyen, T; Sakasegawa, Y1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Cornelis, JJ; Hendrickx, B; Lakhanisky, T; Mouton, RF1
Clarke, CH; Shankel, DM4
Clarke, CH; Wade, MJ1
Hirose, H; Itoh, K; Kido, K; Koyama, K; Maruyama, H; Saruta, T1
Vassalle, M; Yang, L1
Fletcher, JE; Huggins, FJ; Rosenberg, H1
Hasegawa, J; Satoh, H; Vassalle, M1
Carlini, CR; Guimarães, JA; Ribeiro, JM1
Epler, JL; Worthy, TE1
Greengard, P; Quinn, GP; Reid, MB1
Gaudin, D; Gregg, RS; Yielding, KL1
Mason, RG; Read, MS; Saba, SR; Shermer, RW1
Persons, DL; Shankel, DM1
Berger, SP; Crawford, CA; Hsu, K; Reid, MS; Tolliver, BK1
Ardelt, B; Darzynkiewicz, Z; Kapuscinski, J; Piosik, J; Zdunek, M1
CARSTEN, ME; MOMMAERTS, WF1
Booth, D; Chvanov, M; Criddle, DN; Gerasimenko, JV; Gerasimenko, OV; Ghaneh, P; Green, GM; McLaughlin, E; Mukherjee, R; Murphy, JA; Neoptolemos, JP; Petersen, OH; Raraty, MG; Reeve, JR; Sherwood, M; Sutton, R; Tepikin, AV1

Reviews

1 review(s) available for quinacrine and caffeine

ArticleYear
Antimutagenesis in microbial systems.
    Bacteriological reviews, 1975, Volume: 39, Issue:1

    Topics: Acridines; Antipsychotic Agents; Bacteria; Caffeine; Chloramphenicol; Dactinomycin; Dibenzocycloheptenes; DNA Repair; Escherichia coli; Fungi; Genes; Histidine; Manganese; Mutagens; Mutation; Phenothiazines; Polyamines; Purine Nucleosides; Quinacrine; Radiation Effects; Rosaniline Dyes; Ultraviolet Rays; Uracil; Warfarin

1975

Other Studies

30 other study(ies) available for quinacrine and caffeine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Anti-prion activities and drug-like potential of functionalized quinacrine analogs with basic phenyl residues at the 9-amino position.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Blood-Brain Barrier; Cell Line, Tumor; Dogs; Humans; Madin Darby Canine Kidney Cells; Mice; Peptide Fragments; Permeability; Piperazines; Piperidines; Prion Diseases; Prions; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A serological study of removal of UV-induced photoproducts in the DNA of Tetrahymena pyriformis GL: influence of caffeine, quinacrine and chloroquine.
    Photochemistry and photobiology, 1979, Volume: 29, Issue:4

    Topics: Animals; Caffeine; Chloroquine; DNA; DNA Repair; Immunologic Techniques; Photochemistry; Quinacrine; Tetrahymena pyriformis; Ultraviolet Rays

1979
Antimutagens against mutT.
    Molecular & general genetics : MGG, 1977, Sep-09, Volume: 154, Issue:3

    Topics: Arabinose; Caffeine; Escherichia coli; Genes; Mutagens; Mutation; Quinacrine; Spermine

1977
Evidence that caffeine, 8-methoxypsoralen and steroidal diamines are frameshift mutagens for E. coli K-12.
    Mutation research, 1975, Volume: 28, Issue:1

    Topics: Caffeine; Culture Media; Diamines; Escherichia coli; Genetic Code; Hycanthone; Methoxsalen; Mutagens; Mutation; Quinacrine; Transcription, Genetic

1975
Arachidonic acid metabolites and alpha 2-adrenoceptor-mediated glucagon secretion in rats.
    Diabetes research and clinical practice, 1992, Volume: 16, Issue:3

    Topics: Animals; Arachidonic Acids; Aspirin; Caffeine; Clonidine; Glucose; In Vitro Techniques; Islets of Langerhans; Male; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha

1992
Acetylcholine, Ca2+ overload and oscillatory potentials in isolated ventricular myocytes.
    Cardiology, 1991, Volume: 79, Issue:1

    Topics: Acetylcholine; Animals; Caffeine; Calcium; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Myocardium; Norepinephrine; Quinacrine

1991
The importance of calcium ions for in vitro malignant hyperthermia testing.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:6

    Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Quinacrine; Strontium; Succinylcholine; Verapamil

1990
Antimutagenic specificity against spontaneous and nitrofurazone-induced mutations in Escherichia coli K12ND160.
    Mutagenesis, 1989, Volume: 4, Issue:1

    Topics: Caffeine; Cobalt; Colony Count, Microbial; Cytidine; Escherichia coli; Genetic Markers; Guanosine; Mutagenicity Tests; Mutagens; Mutation; Nitrofurazone; Quinacrine; Spermine

1989
On the characteristics of the inward tail current induced by calcium overload.
    Journal of molecular and cellular cardiology, 1989, Volume: 21, Issue:1

    Topics: Animals; Caffeine; Calcium; Electric Conductivity; Electrophysiology; Heart Conduction System; In Vitro Techniques; Membrane Potentials; Purkinje Fibers; Quinacrine; Sheep; Strophanthidin

1989
Antimutagens against spontaneous and induced reversion of a lacZ frameshift mutation in E. coli K-12 strain ND-160.
    Mutation research, 1988, Volume: 202, Issue:1

    Topics: beta-Galactosidase; Caffeine; Cobalt; Escherichia coli; Galactosidases; Guanosine; Isopropyl Thiogalactoside; Mutation; Quinacrine; Spermine; Thioglycosides

1988
Platelet release reaction and aggregation induced by canatoxin, a convulsant protein: evidence for the involvement of the platelet lipoxygenase pathway.
    British journal of pharmacology, 1985, Volume: 84, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Monophosphate; Animals; Arachidonate Lipoxygenases; Blood Platelets; Caffeine; Creatine Kinase; Drug Interactions; Edetic Acid; Epoprostenol; Guinea Pigs; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Lectins; Lipoxygenase; Phosphocreatine; Plant Proteins; Platelet Aggregation; Quinacrine; Rabbits; Species Specificity; Synaptosomes; Thrombin; Toxins, Biological

1985
Characterization of excision repair in Neurospora crassa.
    Journal of bacteriology, 1973, Volume: 115, Issue:2

    Topics: Acridines; Caffeine; Centrifugation, Density Gradient; Deuterium; Disinfectants; DNA; DNA Repair; DNA, Single-Stranded; Molecular Weight; Neurospora; Neurospora crassa; Nitrogen Isotopes; Phosphorus Isotopes; Quinacrine; Radiation Effects; Ultraviolet Rays

1973
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Inhibition of DNA repair replication by DNA binding drugs which sensitize cells to alkylating agents and X-rays.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Alkylating Agents; Caffeine; Chloroquine; Cyanides; Cyclophosphamide; Dinitrophenols; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Drug Combinations; Humans; Hydroxyurea; Injections, Intraperitoneal; Leukocyte Count; Lymphocytes; Protein Binding; Quinacrine; Quinolines; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium; Ultraviolet Rays

1972
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
    Thrombosis et diathesis haemorrhagica, 1972, Feb-29, Volume: 27, Issue:1

    Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds

1972
Effects of antimutagens on prophage induction in E coli lysogenic for lambda.
    Environmental mutagenesis, 1983, Volume: 5, Issue:1

    Topics: Acriflavine; Adenosine; Aminoacridines; Bacteriophage lambda; Caffeine; DNA Repair; Escherichia coli; Quinacrine; Spermine; Ultraviolet Rays; Virus Activation

1983
Evidence for the involvement of phospholipase A2 mechanisms in the development of stimulant sensitization.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:3

    Topics: Animals; Caffeine; Cocaine; Dose-Response Relationship, Drug; Locomotion; Male; Motor Activity; Neurons; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Sprague-Dawley

1996
The modulation of the DNA-damaging effect of polycyclic aromatic agents by xanthines. Part I. Reduction of cytostatic effects of quinacrine mustard by caffeine.
    Biochemical pharmacology, 2002, Feb-15, Volume: 63, Issue:4

    Topics: Antineoplastic Agents; Caffeine; Calorimetry; Cell Cycle; Cell Division; DNA; DNA Damage; Drug Interactions; HL-60 Cells; Humans; Models, Molecular; Quinacrine; Quinacrine Mustard; Spectrophotometry, Atomic; Titrimetry; Tumor Cells, Cultured; Xanthines

2002
THE ACCUMULATION OF CALCIUM IONS BY SARCOTUBULAR VESICLES.
    The Journal of general physiology, 1964, Volume: 48

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Adenosine Triphosphate; Amobarbital; Animals; Anti-Bacterial Agents; Antimycin A; Arsenic; Caffeine; Calcium; Calcium-Transporting ATPases; Chloromercuribenzoates; Dinitrophenols; Iodoacetates; Ions; Metabolism; Microsomes; Muscle Proteins; Nucleotides; Oxalates; Peptides; Pharmacology; Phosphates; Potassium; Pyridoxal Phosphate; Quinacrine; Rabbits; Research; Sodium; Sulfhydryl Compounds; Thiourea

1964
Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells.
    Gastroenterology, 2008, Volume: 135, Issue:2

    Topics: Acetylcholine; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Amylases; Anesthetics, Local; Aniline Compounds; Atropine; Caffeine; Calcium Signaling; Cell Polarity; Cholecystokinin; Cholinergic Agents; Cytosol; Exocytosis; Female; Fluorescent Dyes; Humans; Inositol 1,4,5-Trisphosphate Receptors; Male; Microscopy, Confocal; Middle Aged; Mitochondria; Muscarinic Antagonists; NAD; Pancreas, Exocrine; Quinacrine; Sincalide; Tetrodotoxin; Time Factors; Xanthenes

2008