quinacrine and allopurinol

quinacrine has been researched along with allopurinol in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's7 (31.82)18.2507
2000's8 (36.36)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Howl, JD; Publicover, SJ1
Paul, SM; Schwartz, RD; Skolnick, P1
Doteuchi, M; Hirose, F; Mizui, T; Sato, H1
Au, AM; Chan, PH; Fishman, RA1
Benicourt, C; Junien, JL; Lockhart, BP; Privat, A1
Bockaert, J; Culcasi, M; Lafon-Cazal, M; Pietri, S1
Bloom, SR; Ghatei, MA; Meleagros, L1
Boros, M; Karácsony, G; Kaszaki, J; Nagy, S1
Belzer, FO; Lindell, S; McAnulty, JF; Southard, JH; Vreugdenhil, PK1
McAnulty, JF1
Murphy, HS; Quddus, J; Yu, C1
Balasubramanian, KA; Karnik, S; Thomas, S1
HANDLER, P; RAJAGOPALAN, KV1

Other Studies

22 other study(ies) available for quinacrine and allopurinol

ArticleYear
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Permeabilisation of the sarcolemma in mouse diaphragm exposed to Bay K 8644 in vitro: time course, dependence on Ca2+ and effects of enzyme inhibitors.
    Acta neuropathologica, 1990, Volume: 79, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allopurinol; Animals; Calcium Channels; Cell Membrane Permeability; Diaphragm; Enzyme Inhibitors; Lipoxygenase; Masoprocol; Mice; Phospholipases; Quinacrine; Triazines

1990
Regulation of gamma-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: possible role of oxygen radicals.
    Journal of neurochemistry, 1988, Volume: 50, Issue:2

    Topics: Acetophenones; Animals; Brain; Chlorides; Fatty Acids; Free Radicals; Ion Channels; Male; Oxygen; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Serum Albumin, Bovine; Superoxide Dismutase; Synaptosomes; Xanthine; Xanthine Oxidase; Xanthines

1988
Effect of antiperoxidative drugs on gastric damage induced by ethanol in rats.
    Life sciences, 1987, Aug-10, Volume: 41, Issue:6

    Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Ethanol; Free Radicals; Gastric Mucosa; Iron; Lipid Peroxides; Male; Quercetin; Quinacrine; Rats; Rats, Inbred Strains; Stomach Diseases; Sulfhydryl Compounds; Xanthine Oxidase

1987
Stimulation of phospholipase A2 activity by oxygen-derived free radicals in isolated brain capillaries.
    Journal of cellular biochemistry, 1985, Volume: 27, Issue:4

    Topics: Animals; Brain; Capillaries; Chloroquine; Fatty Acids; Fatty Acids, Unsaturated; Free Radicals; Oxygen; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Quinacrine; Rats; Rats, Inbred Strains; Xanthine Oxidase

1985
Inhibitors of free radical formation fail to attenuate direct beta-amyloid25-35 peptide-mediated neurotoxicity in rat hippocampal cultures.
    Journal of neuroscience research, 1994, Nov-01, Volume: 39, Issue:4

    Topics: Allopurinol; Alzheimer Disease; Amino Acid Oxidoreductases; Amyloid beta-Peptides; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Embryo, Mammalian; Free Radical Scavengers; Free Radicals; Hippocampus; Humans; Indomethacin; Masoprocol; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Oxypurinol; Peptide Fragments; Quinacrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Xanthine Oxidase

1994
NMDA-dependent superoxide production and neurotoxicity.
    Nature, 1993, Aug-05, Volume: 364, Issue:6437

    Topics: Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Calcium Channels; Cell Death; Cells, Cultured; Cerebral Cortex; Computer Simulation; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Nitric Oxide Synthase; Nitroarginine; Quinacrine; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines

1993
Atrial natriuretic peptide and glucagon release in experimental intestinal ischaemia and reperfusion.
    The British journal of surgery, 1994, Volume: 81, Issue:4

    Topics: Allopurinol; Animals; Atrial Natriuretic Factor; Blood Pressure; Free Radicals; Glucagon; Intestines; Ischemia; Male; Quinacrine; Rats; Rats, Wistar; Reperfusion; Time Factors

1994
Reperfusion mucosal damage after complete intestinal ischemia in the dog: the effects of antioxidant and phospholipase A2 inhibitor therapy.
    Surgery, 1993, Volume: 113, Issue:2

    Topics: Allopurinol; Animals; Antioxidants; Dexamethasone; Dogs; Female; Ileum; Intestinal Mucosa; Ischemia; Male; Methylprednisolone; Phospholipases A; Phospholipases A2; Quinacrine; Quinolines; Reperfusion Injury

1993
Successful 7-day perfusion preservation of the canine kidney.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Adenosine; Allopurinol; Animals; Benzamidines; Creatinine; Dogs; Female; Glutathione; Graft Survival; Insulin; Kidney; Kidney Transplantation; Leupeptins; Mersalyl; Mitochondria; Organ Preservation; Organ Preservation Solutions; Oxygen Consumption; Perfusion; Quinacrine; Raffinose; Solutions; Time Factors

1993
A role for the mitochondrial permeability transition pore in ex vivo hypothermic resuscitation of warm ischemic kidney tissue.
    Transplantation proceedings, 1997, Volume: 29, Issue:8

    Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Calcium; Glutathione; In Vitro Techniques; Insulin; Kidney Cortex; Kinetics; Male; Mitochondria; Organ Preservation Solutions; Permeability; Quinacrine; Rabbits; Raffinose; Reperfusion Injury; Temperature

1997
Functional expression of NAD(P)H oxidase p47 in lung microvascular endothelial cells.
    Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3

    Topics: Allopurinol; Animal Population Groups; Animals; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; HL-60 Cells; Humans; Indomethacin; Mice; Mice, Inbred AKR; Microcirculation; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Phosphoproteins; Pulmonary Circulation; Quinacrine; Rotenone; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate

2000
Surgical manipulation of the small intestine and its effect on the lung.
    The Journal of surgical research, 2002, Volume: 106, Issue:1

    Topics: Allopurinol; alpha-Tocopherol; Animals; Arginine; Catalase; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Indomethacin; Intestine, Small; Lung; Male; Neutrophil Activation; Oxidative Stress; Peroxidase; Quinacrine; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase

2002
HEPATIC ALDEHYDE OXIDASE. 3. THE SUBSTRATE-BINDING SITE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Acetaldehyde; Aldehyde Oxidase; Animals; Arsenicals; Benzoates; Binding Sites; Cyanides; Dimercaprol; Enzyme Inhibitors; Liver; Mercaptoethanol; Methanol; Nitrobenzenes; Oxidoreductases; Phenazines; Purines; Pyridines; Quinacrine; Quinolines; Rabbits; Research; Spectrophotometry; Sulfhydryl Compounds; Xanthine Oxidase; Xanthines

1964