quetiapine-fumarate and zopiclone

Alopecia has previously been reported with the atypical antipsychotic medicines olanzapine and risperidone, but has not been described with quetiapine. Case reports of alopecia associated with quetiapine reported to the New Zealand Intensive Medicines Monitoring Programme were reviewed. The World Health Organization international spontaneous reporting database was also searched for additional case reports. Literature searches were conducted for previous reports of alopecia associated with quetiapine. The Intensive Medicines Monitoring Programme database included two case reports of alopecia associated with quetiapine. Assessment of these cases suggested a causal relationship with the medicine. The World Health Organization international database included a further 15 case reports, providing evidence supporting this association. No previously published reports of alopecia associated with quetiapine were identified. In conclusion, these are the first published case reports of alopecia associated with quetiapine.

Topics: Adult; Affective Disorders, Psychotic; Alopecia; Antipsychotic Agents; Azabicyclo Compounds; Bipolar Disorder; Citalopram; Clonazepam; Dibenzothiazepines; Female; Humans; Hypnotics and Sedatives; Piperazines; Quetiapine Fumarate