quercetin has been researched along with catechol* in 1 studies
1 other study(ies) available for quercetin and catechol
Article | Year |
---|---|
Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives.
Aryl diketoacids have been identified as the first SARS-CoV NTPase/helicase inhibitors with a distinct pharmacophore featuring an arylmethyl group attached to a diketoacid. In order to search for the pharmacophore space around the diketoacid core, three classes of dihydroxychromone derivatives were prepared. Based on SAR study, an extended feature of the pharmacophore model of SARS-CoV NTPase/helicase was proposed which is constituted of a diketoacid core, a hydrophobic arylmethyl substituent, and a free catechol unit. Topics: Antiviral Agents; Catechols; Chromones; DNA Helicases; Enzyme Inhibitors; Severe acute respiratory syndrome-related coronavirus; Structure-Activity Relationship | 2009 |