quadazocine has been researched along with u 69593 in 5 studies
| Studies (quadazocine) | Trials (quadazocine) | Recent Studies (post-2010) (quadazocine) | Studies (u 69593) | Trials (u 69593) | Recent Studies (post-2010) (u 69593) |
|---|---|---|---|---|---|
| 81 | 0 | 0 | 524 | 0 | 75 |
| Protein | Taxonomy | quadazocine (IC50) | u 69593 (IC50) |
|---|---|---|---|
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0006 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.194 | |
| Delta-type opioid receptor | Homo sapiens (human) | 3.6437 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0021 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.058 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.588 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Dykstra, LA; Pitts, RC | 1 |
| de Costa, BR; Haaseth, RC; Horan, PJ; Hruby, VJ; Porreca, F; Rice, K | 1 |
| Archer, S; Bidlack, JM; Gatch, MB; Mello, NK; Negus, SS | 1 |
| DeYoung, MB; Lewis, JW; Sumpter, TL; Traynor, JR; Vivian, JA; Woods, JH | 1 |
5 other study(ies) available for quadazocine and u 69593
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.
Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzofurans; Dose-Response Relationship, Drug; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Saimiri | 1994 |
Differential antagonism of bremazocine- and U69,593-induced antinociception by quadazocine: further functional evidence of opioid kappa receptor multiplicity in the mouse.
Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzodiazepines; Benzomorphans; Cyclohexanes; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Structure-Activity Relationship; Thiophenes | 1993 |
Effects of the structurally novel opioid 14 alpha, 14' beta-[dithiobis [(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) on schedule-controlled behavior and thermal nociception in rhesus monkeys.
Topics: Analgesics; Animals; Azocines; Behavior, Animal; Benzeneacetamides; Female; Fentanyl; Hot Temperature; Hydromorphone; Macaca mulatta; Male; Morphine; Narcotic Antagonists; Pain; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1996 |
kappa-Opioid receptor effects of butorphanol in rhesus monkeys.
Topics: Analgesics, Opioid; Animals; Azocines; Benzeneacetamides; Butorphanol; Cinnamates; Conditioning, Operant; Discrimination Learning; Diuresis; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Injections, Intramuscular; Macaca mulatta; Male; Morphine Derivatives; Nalbuphine; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa | 1999 |