quadazocine and norbinaltorphimine
quadazocine has been researched along with norbinaltorphimine in 4 studies
Compound Research Comparison
| Studies (quadazocine) | Trials (quadazocine) | Recent Studies (post-2010) (quadazocine) | Studies (norbinaltorphimine) | Trials (norbinaltorphimine) | Recent Studies (post-2010) (norbinaltorphimine) |
|---|---|---|---|---|---|
| 81 | 0 | 0 | 918 | 0 | 205 |
Protein Interaction Comparison
| Protein | Taxonomy | quadazocine (IC50) | norbinaltorphimine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0104 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0029 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.212 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.024 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0036 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Butelman, ER; DeCosta, BR; Walker, EA; Woods, JH | 1 |
| Butelman, ER; Ko, MC; Woods, JH | 1 |
| Bian, JS; Wang, HX; Wong, TM; Wu, S; Yu, XC; Zhang, WM | 1 |
Other Studies
4 other study(ies) available for quadazocine and norbinaltorphimine
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Opioid thermal antinociception in rhesus monkeys: receptor mechanisms and temperature dependency.
Topics: Alfentanil; Analgesics; Animals; Azocines; Benzimidazoles; Benzomorphans; Dose-Response Relationship, Drug; Female; Hot Temperature; Macaca mulatta; Male; Nalbuphine; Naltrexone; Nociceptors; Pyrrolidines; Receptors, Opioid; Tail | 1993 |
Activation of peripheral kappa opioid receptors inhibits capsaicin-induced thermal nociception in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Azocines; Benzomorphans; Capsaicin; Dynorphins; Female; Hot Temperature; Ligands; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Pain Measurement; Peptide Fragments; Receptors, Opioid, kappa | 1999 |
Effects of U50488 and bremazocine on [Ca2+]i and cAMP in naive and tolerant rat ventricular myocytes: evidence of kappa opioid receptor multiplicity in the heart.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Drug Resistance; Electric Stimulation; Heart; Heart Ventricles; Male; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 1999 |